• Title/Summary/Keyword: Res

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Resveratrol raises in vitro anticancer effects of paclitaxel in NSCLC cell line A549 through COX-2 expression

  • Kong, Fanhua;Zhang, Runqi;Zhao, Xudong;Zheng, Guanlin;Wang, Zhou;Wang, Peng
    • The Korean Journal of Physiology and Pharmacology
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    • v.21 no.5
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    • pp.465-474
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    • 2017
  • The aim of this study was to determine the raising anticancer effects of resveratrol (Res) on paclitaxel (PA) in non-small cell lung cancer (NSCLC) cell line A549. The $10{\mu}g/ml$ of Res had no effect on human fetal lung fibroblast MRC-5 cells or on A549 cancer cells and the 5 or $10{\mu}g/ml$ of PA also had no effect on MRC-5 normal cells. PA-L ($5{\mu}g/ml$) and PA-H ($10{\mu}g/ml$) had the growth inhibitory effects in NSCLC cell line A549, and Res increased these growth inhibitory effects. By flow cytometry experiment, after Res ($5{\mu}g/ml$)+PA-H ($10{\mu}g/ml$) treatment, the A549 cells showed the most apoptosic cells compared to other group treatments, and after additional treatment with Res, the apoptosic cells of both two PA concentrations were raised. Res+PA could reduce the mRNA and protein expressions of COX-2, and Res+PA could reduce the COX-2 related genes of VEGF, MMP-1, MMP-2, MMP-9, $NF-{\kappa}B$, Bcl-2, BclxL, procollagen I, collagen I, collagen III and CTGF, $TNF-{\alpha}$, $IL-1{\beta}$, iNOS and raise the TIMP-1, TIMP-2, TIMP-3, $I{\kappa}B-{\alpha}$, p53, p21, caspase-3, caspase-8, caspase-9, Bax genes compared to the control cells and the PA treated cells. From these results, it can be suggested that Res could raise the anticancer effects of PA in A549 cells, thus Res might be used as a good sensitizing agent for PA.

A Study on Detection and Resolving of Occlusion Area by Street Tree Object using ResNet Algorithm (ResNet 알고리즘을 이용한 가로수 객체의 폐색영역 검출 및 해결)

  • Park, Hong-Gi;Bae, Kyoung-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.10
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    • pp.77-83
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    • 2020
  • The technologies of 3D spatial information, such as Smart City and Digital Twins, are developing rapidly for managing land and solving urban problems scientifically. In this construction of 3D spatial information, an object using aerial photo images is built as a digital DB. Realistically, the task of extracting a texturing image, which is an actual image of the object wall, and attaching an image to the object wall are important. On the other hand, occluded areas occur in the texturing image. In this study, the ResNet algorithm in deep learning technologies was tested to solve these problems. A dataset was constructed, and the street tree was detected using the ResNet algorithm. The ability of the ResNet algorithm to detect the street tree was dependent on the brightness of the image. The ResNet algorithm can detect the street tree in an image with side and inclination angles.

Vehicle License Plate Recognition System using SSD-Mobilenet and ResNet for Mobile Device (SSD-Mobilenet과 ResNet을 이용한 모바일 기기용 자동차 번호판 인식시스템)

  • Kim, Woonki;Dehghan, Fatemeh;Cho, Seongwon
    • Smart Media Journal
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    • v.9 no.2
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    • pp.92-98
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    • 2020
  • This paper proposes a vehicle license plate recognition system using light weight deep learning models without high-end server. The proposed license plate recognition system consists of 3 steps: [license plate detection]-[character area segmentation]-[character recognition]. SSD-Mobilenet was used for license plate detection, ResNet with localization was used for character area segmentation, ResNet was used for character recognition. Experiemnts using Samsung Galaxy S7 and LG Q9, accuracy showed 85.3% accuracy and around 1.1 second running time.

A New Spray Chrysanthemum Cultivar, "Moon Festival" with Vigorous Semi-Double Flower Type and Light-ivory White Petals for Cut Flower

  • Lim, Jin-Hee;Shin, Hak-Ki;Park, Sang Kun;Cho, Hae-Ryong;Rhee, Hye-Kyung;Kim, Mi-Seon;Joung, Hyang Young
    • Korean Journal of Breeding Science
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    • v.40 no.3
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    • pp.336-339
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    • 2008
  • A new spray chrysanthemum cultivar, 'Moon Festival' was released by National Horticultural Research Institute (NHRI), Rural Development Administration (RDA), Korea in 2007. A cross was made in 2002 between '01B1-559', a breeding line of NHRI and 'Baeksokuk', a spray cultivar with white petals. Trials were conducted from 2005 to 2007 for evaluation and selection of this cultivar, including shading culture in summer and retarding culture in autumn. The natural flowering time of "Moon Festival" is late October, but year-round flowering is possible by shading and lighting treatment. The cultivar is semi- double type flowers with light-ivory white petals and green flower center. Flower neck and stem are very hardy. The diameter of flower is 67.5 mm. The number of flowers per stem and petals per flower is 11.5 and 100.5, respectively. The days to flowering under the short day is about 54 in autumn season.

Comparative Study on Hydropower Generation in the Han River Basin by Using HEC-ResPRM and Linear Programming (HEC-ResPRM과 선형계획법을 이용한 한강수계 댐 발전량 비교 연구)

  • Ji, Jungwon;Lee, Eunkyung;Yi, Jaeeung
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.141-141
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    • 2015
  • IPCC 5차 보고서에서 기술되어 있는 것처럼 기후시스템의 온난화는 명백하며, 1950년 이후 관측된 많은 변화들은 지난 수천 년간 전례가 없는 것이었다. 지구 온난화로 대표되는 기후변화는 이제 일부 국가에 국한되는 문제가 아니라 전 지구적인 문제가 되었다. RCP 시나리오에 따라 차이는 있으나 대한민국의 경우 연평균 강수 총량은 증가할 것이라 예상되는 반면 총 예상 강우 일수는 감소하여 집중호우의 발생빈도가 증가될 것이라 예상되고 있다. 이에 따라 수자원의 효율적 이용에 대한 필요성 또한 증가하고 있는 실정이다. 본 연구에서는 수자원의 효율적 이용을 위해 한강수계 9개 댐(화천, 춘천, 소양강, 의암, 청평, 충주, 괴산, 횡성, 팔당)을 대상으로 HEC-ResPRM과 선형계획법을 이용하여 발전량을 최적화 하였다. HEC-ResPRM은 미공병단 수문공학센터에서 개발한 저수지운영 최적화 모형으로 홍수 조절, 관개, 발전, 레크리에이션 등 다양한 요구조건을 만족시킬 수 있는 최적의 저수지 운영방안 도출이 가능하다. 본 연구에서는 HEC-ResPRM 모형과 선형계획법을 이용한 운형모형의 결과자료를 비교하였으며 이를 통해 HEC-ResPRM 모형의 특징과 활용 가능성을 확인하였다.

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A New Spray Chrysanthemum Cultivar, 'Golden Festival' with Vigorous Semi-Double Flower of Yellow Petals for Cut Flower

  • Lim, Jin-Hee;Shin, Hak-Ki;Park, Sang Kun;Cho, Hae-Ryong;Rhee, Hye-Kyung;Kim, Mi-Seon;Joung, Hyang Young
    • Korean Journal of Breeding Science
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    • v.40 no.4
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    • pp.495-498
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    • 2008
  • A new spray chrysanthemum cultivar, 'Golden Festival' was released by National Horticultural Research Institute (NHRI), Rural Development Administration (RDA), Korea in 2007. It was selected from the progenies of open-pollination of 'Torbay' in 2002. Trials were conducted from 2005 to 2007 for evaluation and selection of this cultivar, including shading culture in summer and retarding culture in autumn. The natural flowering time of 'Golden Festival' is late October, but year-round flowering is possible by shading and lighting treatment. The cultivar is semi-double type flowers with bright yellow petals and green flower center. Flower neck and stem are very hardy. The diameter of flower is 56.5 mm. The number of flowers per stem and petals per flower are 12.0 and 93.5, respectively. The days to flowering under the short day treatment is about 50 in spring season.

A New Spray Chrysanthemum Cultivar, "Cherry Blossom" with Resistant to White Rust, Single Flower Type and Bright Pink Petals for Cut Flower

  • Lim, Jin-Hee;Shin, Hak-Ki;Park, Sang Kun;Cho, Hae-Ryong;Rhee, Hye-Kyung;Kim, Mi-Seon;Joung, Hyang Young
    • Korean Journal of Breeding Science
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    • v.40 no.4
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    • pp.439-442
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    • 2008
  • A new spray chrysanthemum cultivar, 'Cherry Blossom' was released by National Horticultural Research Institute (NHRI), Rural Development Administration (RDA), Korea in 2007. A cross was made in 2002 between 'Relance', a spray cultivar with red petals and resistant to white rust and 'Yeonja', a spray cultivar with pink petals. Trials were conducted from 2005 to 2007 for the evaluation and selection of this cultivar, including shading culture in summer and retarding culture in autumn. The natural flowering time of "Cherry Blossom" is late October, but year-round flowering is possible by shading and lighting treatment. This cultivar is single type flowers with dark pink petals and green flower center and resistant to white rust. It is very stable color of petals when the variety is cultivated under high temperature conditions in summer season. The diameter of flower is 55.0 mm. The number of flowers per stem is 10.5 and the number of petals per flower is 24.0. The days to flowering under the short day treatment is about 45 in spring season.