• Restorative Dentistry and Endodontics
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• 제36권3호
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• pp.211-218
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• 2011

연구목적: 의도적 재식술은 재근관치료와 치근단 수술이 곤란하거나 실패한 경우 치아를 유지하기 위한 치료 방법이다. 성공적인 의도적 재식술을 위해서 파절 없는 안전한 발치는 필수적인 과정이다. 이를 위해 최근 의도적 재식술을 위한 비외상성 안전 발치법이 소개되었다. 환자 및 방법: 분당서울대학교 병원 치과 보존과에서 의도적 재식술을 시행한 96명의 환자를 대상으로 하였다. 재근관 치료가 실패하였거나 해부학적 접근의 어려움 등으로 치근단 수술이 곤란한 경우나 환자가 거부한 경우를 대상으로 하였다. 술전교정적 정출술을 약 2-3주간 시행하여 치아의 동요도를 증가시키고 동시에 치주인대의 양을 증가시켰다. 이후 Physics Forceps를 이용하여 발치하였으며 결과에 대해 분석하였다. 결과: 96개의 치아는 상,하악 소구치 또는 대구치였다. 완전한 발치 성공은 93% (n = 89)였으며 제한적인 성공(치근의 일부가 부러짐)은 2% (n = 2), 골절제술을 동반하여 발치한 경우가 5% (n = 5)였다. 임상적인 성공률은 95%였으며 전체적인 발치 성공률은 100% 였다. 결론: 비외상성 안전 발치법은 의도적 재식술을 위해 재현성 있고 예측가능한 발치방법으로 볼 수 있다.

• 한국환경복원기술학회지
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• 제10권3호
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• pp.52-59
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• 2007

This study was carried out to select proper species for early stage replantation in cutting-slope area of the Baekdu Range roadside. In the cutting-slope area and upper forest area of the cutting-slope area, sample plots of 46 were selected and their vegetations and environmental factors were investigated. We found total 90 species in the 46 plots. We found Festuca arundinacea in 27 plots of the 46 plots. We also found Lespedeza bicolor in 26 plots, Eragrostis curvula in 22 plots, Artemisia princeps var. orientalis in 19 plots, Erigeron annuus and Pinus densiflora in 15 plots, Lactuca indica var. laciniata in 14 plots, Miscanthus sinensis in 13 plots, Oenothera odorata, Commelina communis, and Humulus japonicus in 11 plots, Lespedeza cuneata in 10 plots, Salix koreensis and Salix hulteni in 9 plots, Festuca rubra, Youngia denticulata, Aster scaber, and Festuca arundinacea in 8 plots, Chenopodium album var. centrorubrum in 7 plots, Patrinia villosa and Erigeron canadensis in 6 plots, and Setaria viridis, Digitaria sanguinalis, and Dactylis glomerata in 5 plots.The dominancy of Festuca arundinacea, Eragrostis curvula, Lespedeza bicolor, Miscanthus sinensis, Pinus densiflora, Festuca arundinacea, Festuca rubra, Artemisia princeps var. orientalis, Erigeron annuus, Lespedeza cuneata, Dactylis glomerata, Salix koreensis, Alnus hirsuta, Pueraria thunbergiana, Medicago sativa, Lactuca indica var. laciniata, and Digitaria sanguinalis were 13.41% 11.87%, 4.88%, 4.56%, 3.38%, 2.29%, 2.14%, 2.14%, 1.99%, 1.95%, 1.54%, 1.47%, 1.44%, 1.37%, 1.15%, 1.13%, 1.07% in the roadside cutting-slope, respectively. The dominancy of Rhododendron mucronulatum, Lindera obtusiloba, Rhus trichocarpa, Quercus mongolica, Lespedeza bicolor, Rhododendron schlippenbachii, and Quercus serrata 22.15%, 13.36%, 13.14%, 12.03%, 11.74%, 11.20%, and 11.14% in shrub layer of the upper forest area, respectively. The species of Rhododendron mucronulatum, Lindera obtusiloba, Rhus trichocarpa, Rhododendron schlippenbachii, Zanthoxylum schinifolium, Weigela subsessilis, Stephanandra incisa, Rhamnus davurica, Ligustrum obtusifolium, Lindera erythrocarpa, Rosa multiflora, Rubus coreanus, Symplocos chinensis for. pilosa, Smilax china, Prunus sargentii, and Staphylea bumalda may be more helpful in stabilizing of the cutting-slope area and making harmony with the surrounding forest area.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제15권3호
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• pp.199-210
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• 1993

Many surgeons are on the point of bone excision and reconstruction of the bone defects by autograft. xenograft, and allograft in the treatment of begin and malignant tumors of bone. Of all type of bone grafts, we received the autograft as the best ideal bone graft. Of autogenic bone graft, replantation of excised autogenic bone for reconstructiong the bone defects has been the ideal method until now, but early bone healing reponses and tumor cell devitalization after replantation of excised autogenic bone have not been identified for clinical applications. So, to evaluate bone healing response after replantation in rabbit's calvarial bone, we divided the experimental group into three groups. Group 1 is a fresh autogenous bone group. Group 2 is a deep frozen group. Group 3 is freeze-dried demineralized group. Obtained result were as followed: 1. Inflammatory cell infiltration appeared at I week and disappeared at 4 weeks in all experimental group, Especially, severe inflammatory cell infiltration showed in fresh autogenous bone group at 2 weeks. Group 3 is the least showing group on the point of inflammatory cell infiltration. 2. Osteoblastic activity evenly increased upto 4 weeks and maintained to 6 weeks and decreased after this period, especially osteoblastic activity in group 2 is less than group 1 and group 3. We can't discriminate between osteoblastic activity of group 1 and that of group 3. 3. In new bone formation, group 3 was more active than any other groups at early stage, but there were little differences among three experimental groups at later state. 4. Bone resorption around the grafted bone slightly appeared at 1 week and disappeared at 4 weeks in all experimental groups. We can find the more bone resorption in group 2 at 2 weeks than any other groups. We could suggest, as appears from our results, that freeze-dried deminiralized bone graft is the useful bone graft in the clinical applications of excised autogenic bone.

• 한국환경복원기술학회지
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• 제7권1호
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• pp.59-67
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• 2004

This study was carried out to select proper species for early stage replantation in granite forest roads cut-slope. From one to fourteen year elapsed forest roads in eight regional areas of Gyeongsang-do and Jeolla-do, sample plots were selected, and their vegetations and environmental factors were investigated. Soil organic matter, total nitrogen, soil moisture content, and bulk density in the granite weathering soils were below 0.4%, 0.03%, 12.4%, and above 1.2g/$cm^3$, respectively. The result indicated that the soil was not good for plant growth. The environmental factors affecting distribution of species in the granite forest roads were the elapsed year, elevation, and cut-slope aspect. Invaded species with high frequency in the forest road cut-slope ordered Pinus densiflora, Lespedeza bicolor, Rubus crataegifolius, Alnus hirsuta, Youngia denticulata, Patrinia villosa, Artemisia princeps var. orientalis, Zanthoxylum schinifolium, and Dactylis glomerata. Herbs seeded in earth stage such as Dactylis glomerata, Eragrostis curvula, Festuca arundinacea, Lespedeza sp., and Amorpha fruticosa had changed into perennial herbs and shrubs such as Youngia denticulata, Patrinia villosa, Aster scaber, Patrinia scabiosaefolia, Melica onoei, Astilbe chinensis var. davidii, Chrysanthemum zawadskii var. latilobum, Pueraria thunbergiana, Stephanandra incisa, and Clematis apiifolia, and had changed into plants such as Artemisia princeps var. orientalis, Artemisia keiskeana, Miscanthus sinensis, Pinus densiflora, Rhododendron mucronulatum, Rubus crataegifolius, and Zanthoxylum schinifolium according to elapsed year of forest roads. Leguma such as Lespedeza sp., Pueraria thunbergiana, Amorpha fruticosa, etc., herbs such as Artemisia keiskeana, Artemisia princeps var. orientalis, Chrysanthemum zawadskii var. latilobum, Miscanthus sinensis, etc., and woody plants such as Pinus densiflora, Rubus crataegifolius, Rhododendron mucronulatum, etc., with foreign herbs were considered as proper species for replantation in granite forest road cut-slope.

• Journal of Periodontal and Implant Science
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• 제45권3호
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• pp.111-119
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• 2015

Purpose: The purpose of this animal study was to perform a histological and histomorphometric analysis in order to elucidate the effect of fibroblast growth factor-2 (FGF-2) on injured periodontal ligament (PDL) and cementum after tooth replantation in dogs. Methods: The roots of 36 mandibular premolars from six mongrel dogs were used in this study. The roots were randomly divided into three groups: (1) a positive control group (n=12), in which the PDL was retained; (2) a negative control group (n=12), in which the PDL and the cementum between the notches were removed; and (3) an experimental group (n=12), in which the PDL and the cementum between the notches were removed and the roots were soaked in an FGF-2 solution ($30{\mu}g/0.1mL$). After treating the root surfaces, the extracted roots were replanted into extraction sockets. The animals were sacrificed four and eight weeks after surgery for histologic and histomorphometric evaluation. Results: At four and eight weeks, normal PDLs covered the roots in the positive control group. In the negative control group, most replanted roots showed signs of replacement resorption. In the experimental group, new PDL-like tissue and cementum-like tissue were observed to partially occupy the region between the root surfaces and the newly formed bone. Histomorphometric analysis showed that the mean length of the newly formed cementum-like tissue on the roots treated with FGF-2 was significantly greater than that of the tissue on the roots in the negative control group (four weeks, P=0.008; eight weeks, P=0.042). However, no significant differences were observed between the roots treated with FGF-2 and the negative control roots with respect to newly formed PDL-like tissue. Conclusions: The results of this study suggest that use of FGF-2 on injured root surfaces promotes cementogenesis after tooth replacement in dogs.

• 대한소아치과학회지
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• 제26권4호
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• pp.688-702
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• 1999

치아 재식 후 시간경과에 따른 치수조직의 재혈관화와 신경재지배의 변화를 관찰하기위해 생후 35일 된 흰쥐 (Sprague dawley) 56마리를 대상으로 상악우측 제 1대구치를 발치 즉시 재식한 후 1일, 2일, 3일, 1주, 2주, 4주, 6주 간격으로 희생시켜 먹물을 이용한 혈관조영술과 CGRP를 이용한 면역조직화학적방법으로 각기 시행하여 다음과 같은 결론을 얻었다. 1. 재혈관화와 CGRP 면역반응신경섬유의 재지배는 재식후 1일에서 근심측 치수조직에서는 이미 이루어졌으나 원심측은 미약했다. 재식후 2일에 전치수조직에서 재혈관화와 신경재지배가 이루어졌으며 이후 6주까지 시간경과에 따라 분포밀도가 증가하였으나 대조군에 비해서는 약하게 나타났다. 2. 재식후 1주에서부터 술후 상아질이 형성되기 시작하였으며 재식후 6주에서는 대조군에 비해 상대적으로 치수강이 좁아진 양상을 보였다. 3. 재혈관화와 신경재지배는 거의 같은 시기에 이루어지는 것으로 나타났으며 밀접한 관련성이 있는 것으로 보인다.

• Restorative Dentistry and Endodontics
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• 제26권4호
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• pp.296-306
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• 2001

The purpose of this study was to observe the effect of dexamethasone and osteogenic protein-1(BMP-7) on bone, cementum and periodontal tissue regeneration. A total of 60 Sprague-Dawley white female mice were selected and beta-APN was used for five days to extract the maxillary first molar a traumatically. After the extraction of the teeth, the mesiobuccal root canal was filled with Caviton$^{\circledR}$. The teeth were etched with citric acid for 1 min and coated with one of four different experimental solutions : DEX(500nM/ml), DEX(1000nM/ml), OP-1(100$\mu\textrm{g}$/ml) and OP-1(500$\mu\textrm{g}$/ml) for three minutes depending on the group. All teeth were then replanted under microscope. All replantation procedures were done within 30 minutes. Teeth that were replanted after 30 minutes of bench dry only was used as positive control. All animals were sacrificed at 3 weeks following replantation and histologic observtion was done. The results were as follows ; 1. Active root resorption rate was decreased by the order of OP-1(500$\mu\textrm{g}$/ml), DEX(1000nM/ml), OP-1(100$\mu\textrm{g}$/ml), and DEX(500nM/ml). There was statistically less root resorption in OP-1 (500$\mu\textrm{g}$/ml) and DEX(1000nM/ml) group(P<0.05). 2. The group with higher concentration of dexamethasone(1000nM/ml) had statistically more bone union compared to positive control group(P<0.05),but there were no significant differences among four experimental groups. 3. OP-1(500$\mu\textrm{g}$/ml) and DEX(1000nM/ml) groups showed less degree of inflammation compared to the OP-1(100$\mu\textrm{g}$/ml). DEX(500nM/ml), and positive control group (P<0.05). In conclusion, the group with higher concentration of OP-1 had the best results on root resorption, bone ankylosis and anti-inflammatory effects compared to the other experimental groups, but a long-term study is also necessary to evaluate the exact pharmacological effects of the drugs in the future.

• 한국환경생태학회지
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• 제17권3호
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• pp.201-209
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• 2003

본 연구는 전라남도와 경상남도의 4개 시$.$군에서 개설 후 1∼15년 경과한 임도에서 경과년수별로 절토 사면에 조사구를 설치하고. 식생조사와 환경인자를 조사하였다. 경과년수에 따라 침입하는 종 수와 피복도는 점차 증가하였으며, 초본류의 출현비율은 감소하였고, 목본류의 출현비율은 증가하였다. Ordination 분석을 실시한 결과 종의 분포에 영향을 미치는 요인은 시공 후 경과년수, 절토경사, 해발고, 절토사면 방향 등으로 나타났다. 임도사면의 녹화를 위해서는 시공 초기에 파종하던 종 이외에 쑥. 뱀딸기, 참억새, 칡, 산초나무, 붉나무, 병꽃나무 등이 적합할 것으로 판단된다. 임도사면에 출현한 관속식물은 77과 190속 233종 38변종으로 총 271종이며. 그 중 귀화식물은 18종이 출현하였다. 출현종의 빈도 우선순위를 보면. 산딸기, 쑥, 산초나무, 칡, 소나무. 조록싸리, 큰까치 수영, 싸리. 이고들빼기. 참억새, 개망초 등의 순이다.

• Restorative Dentistry and Endodontics
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• 제36권1호
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• pp.19-25
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• 2011

연구목적: 인류지질학적으로 동양인에게서 많이 발견되는 C-형 근관계를 가진 하악 제2대구치는 근관치료나 비외과적 재치료에 실패하는 경우 외과적 재치료 방법으로 의도적 재식술을 시행하게 되는데 그 성공률에 대한 보고가 없었다. 따라서 본 연구의 목적은 C-형 근관계를 가진 하악 제2대구치에 의도적 재식술을 시행한 환자의 기록을 후향적으로 조사하여 치료 결과에 따른 성공률을 확인할 뿐 아니라 치료전 존재하던 치근단 병소가 성공률에 영향을 미치는 바에 대하여 알아보는 것이다. 연구 재료 및 방법: 연구를 위해 2005년 1월부터 2007년 12월에 걸쳐 서울대학교치과병원 치과보존과에 내원하여 하악 제2대구치에 의도적 재식술을 받은 52명의 환자 기록을 조사하였으며 7개의 치아는 정기적인 내원검진 기록이 없어서 조사 대상에서 제외하였고 다른 6개의 치아는 C-형 근관계의 조건에 해당되지 않아 연구에서 제외하였다. 정기 내원후 시행한 임상 검사와 방사선 사진 기록을 후향적으로 검토하여 성공이나 불완전한 치유 또는 실패등의 치료 결과에 대하여 판단하였다. 결과: C-형 근관계를 가진 29개의 하악 제2대구치에 시행한 의도적 재식술의 성공률은 72.4%로 관찰되었으며 치료전 치근단 병소가 존재한 경우의 성공률은 치근단 병소가 없었던 경우와 유사한 것으로 확인되었다. 결론: 본 연구결과 C-형 근관계를 가진 하악 제2대구치의 근관치료가 실패한 경우 시행하게 되는 의도적 재식술은 술전 병소의 존재 유무에 상관없이 치근단 수술의 성공률과 유사한 결과를 얻을 수 있는 치료라고 사료된다.

• 대한미세수술학회:학술대회논문집
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• 대한미세수술학회 1992년도 제12차 학술대회
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• pp.77-77
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• 1992