• Title/Summary/Keyword: Repeat time

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SWAT model calibration/validation using SWAT-CUP II: analysis for uncertainties of simulation run/iteration number (SWAT-CUP을 이용한 SWAT 모형 검·보정 II: 모의 실행 및 반복 횟수에 따른 불확실성 분석)

  • Yu, Jisoo;Noh, Joonwoo;Cho, Younghyun
    • Journal of Korea Water Resources Association
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    • v.53 no.5
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    • pp.347-356
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    • 2020
  • The main objective of the study is to propose the most efficient SWAT model calibration method using SWAT-CUP with less computing time and high performance. In order to achieve the goal, Case1-3 (250, 500, and 1,000 simulation runs) and Case4 (1,000 simulation runs in the first iteration and then 500 simulation runs for the following iterations) were defined to compare the results. When evaluating the values of the objective function, Case2 and Case3 reached the same value after the fourth iteration, and Case1 reached the closed value of Case2-3 after the eighth iteration. However, the final estimates of the parameters had different ranges in Cases1-3, and only the results of Case3 and Case4 converged similarly. Thus, it can be considered that the parameter calibration results are highly affected by the initial number of simulation runs. On the other hand, SWAT simulation results did not show the significant difference after the first iteration, unlike the parameter ranges. From the analysis results, we can conclude that the most suitable and effective method was to repeat one or two times of iterations with a sufficient number of simulation runs, as in Case4.

Phase II Study of Pemetrexed as Second or Third Line Combined Chemotherapy in Patients with Colorectal Cancer

  • Wu, Xue-Yan;Huang, Xin-En;You, Shan-Xi;Lu, Yan-Yan;Cao, Jie;Liu, Jin;Xiang, Jin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.3
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    • pp.2019-2022
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    • 2013
  • Purpose: To investigate the safety and efficacy of pemetrexed combined with chemotherapy as second or third line in patients with stage IV colorectal cancer (CRC). Patients and Methods: This trial was conducted to evaluate the effectiveness and safety of pemetrexed given to patients with recurrent or metastatic colorectal carcinoma who previously received 5-FU-based chemotherapy. All patients were required to have a histological diagnosis of colorectal adenocarcinoma with measurable metastatic disease and prior chemotherapy. Patients received pemetrexed at a dose of 500 $mg/m^2$ by 10 minute infusion on day 1, repeated every 21 days. Doses were modified depending on nadir counts. Combined chemotherapy included Oxaliplatin, Irinotecan and cis-platinum. Results: Thirty patients were enrolled and twenty-nine were evaluable for response. One patient did not have repeat radiological testing to determine response because he went off study after only one cycle of treatment for economic reasons. For 29 evaluable patients, 1 partial response, 6 stable disease and 22 progressive disease were recorded. Response rate was 3.45% (1/29). All responses occurred in patients receiving a starting dose of pemetrexed 500 $mg/m^2$. Median time to progression for all eligible patients was 2.5 months. The most common toxicities experienced were mild to moderate fever, hepatic damage, myelosuppression, nausea, vomiting, constipation, abdominal pain, diarrhea, and skin rash. Conclusion: Pemetrexed at 500 $mg/m^2$ given every three weeks combined with chemotherapy is associated with moderate response and good tolerability in patients with stage IV CRC.

Growth of Felonies after the 1997 Financial Crisis in Korea (외환위기 이후 흉악범죄의 증가와 정부의 범죄억지정책)

  • Kim, Duol;Kim, Jee Eun
    • KDI Journal of Economic Policy
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    • v.31 no.2
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    • pp.155-194
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    • 2009
  • The Korean economy successfully overcame the macroeconomic downturns driven from the Asian financial crisis in a very short period of time. The economic shock, however, generated a variety of social problems, one of which was the increase in felonies (homicides, robbery, rape, and arson), or degradation of public safety. We argue that the Korean criminal policy has not been effective to ameliorate the rising trends in crime caused by the financial crisis. In order to substantiate this claim, we assess the effectiveness of criminal policy: policing, sentencing, and corrections. First, there has been resource shortage in policing since the 1997 financial crisis. For the past ten years, the investment of human resource and budget in the police has been virtually stagnant, as well as in prosecutors' investigation activities. The insufficient resource allocation in policing caused a huge decline in arrest rates and prosecution rates. Second, the Korean judicial system has not increased the severity of punishment. Comparing the pre- and the post-financial crisis period, the average length of prison sentence by the courts has declined. Given the degrading in the quality of crime and the decreasing amount of inputs into the policing and prosecution, the government should have increased the severity of punishment to deter crime. Third, we found that the government hired more officers and allocated larger budget into prison and probation. However, it is difficult to suggest that the increased level of resources in correctional programs have been effective in preventing released prisoners from committing future crimes. This is because the number of repeat offenders convicted of more than a third offense increased dramatically since 1997, pushing felonies upward. In sum, the government organizations failed to respond respectively or to make coordinated actions, eventually causing a dramatic increase in crimes. This research brings explicit policy implications. In order to prevent possible additional degradation of public safety, the government must put more efforts into increasing the effectiveness of policy and to investing more resources into said policies. We also emphasize the importance of the institutional mechanisms which foster policy coordination among the Police, the Prosecutor's Office, the Ministry of Justice, and other relevant government organizations.

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Effects of an Anti-Smoking Program to Prevent Lung Cancer among Urban Aboriginals in Taiwan

  • Lin, Mei-Hsiang;Huang, Sheu-Jen;Shih, Whei-Mei Jean;Wang, Pao-Yu;Lin, Li-Hui;Hsu, Hsiu-Chin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6451-6457
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    • 2013
  • Background and Purpose: Indigenous people who leave their hometowns and move to the city to earn a living became urban aboriginals. During the process of adapting to urban living situations, they may use various coping strategies such as smoking to overcome their stress. Therefore, it is crucial to provide health education including smoking prevention, increasing knowledge regarding of tobacco hazard, self-efficacy of anti-smoking, and adjusting smoking behavior so as to empower their anti-smoking motivation to prevent lung cancer. The purpose of this study was to explore the effectiveness of an anti-smoking program on urban aboriginals in Taiwan. Methods: A quasi-experimental study design with purposeful sampling was employed. A total of 125 aboriginal subjects were recruited from two local churches at Shu Lin area in northern Taiwan. Subjects were divided into an experimental group (n =64 ) and a control group (n = 61). Both took pre-tests in order to set baseline values, and only the experimental group participated for 3-weeks in the anti-smoking program classes. Both groups took post-tests immediately after the intervention in order to evaluate the immediate effects of the teaching program, and a follow-up test was conducted four weeks after the intervention. Data were analyzed using descriptive statistics, one-way ANCOVA, and repeat measure ANCOVA. Results: After controlling for confounding variables, the results showed that there were statistically significant differences in the self-efficacy of anti-smoking and smoking behavior between experimental and control groups in the immediately post-test and the follow-up test (p < 0.05). However, there was no significant differences in the recognition of hazards of smoking at eiter time point. Conclusions and Implications for Practice: The findings of this study revealed that the anti-smoking program effectively improved self-efficacy of anti-smoking, and decreased the smoking behavior in urban aboriginals. They provide useful information as a reference regarding of aboriginal health promotion to health providers. It is imperative that anti-smoking be reinforced for those regular smokers to prevent induction of lung cancer.

Analysis of SNS(Social Networking Service) functions applicable to electronic commerce for building regular relationship with customers (전자상거래에서 단골관계 형성을 위한 SNS의 기능 분석 및 활용)

  • Gim, Mi-Su;Woo, Won-Seok
    • Journal of the Korea Society of Computer and Information
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    • v.20 no.4
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    • pp.131-138
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    • 2015
  • One of the most conspicuous characteristics of a business model that pursues expanding customer relationship is that it tries to lock in customers by encouraging them to repeat purchase in the long-term with the help of "Follow" function in Social Networking Service (SNS), which enables producers to automatically register the customers as potentially important ones and to offer them customized marketing services. In the value chain of the agriculture sector, producers of agricultural products can use SNS functions to provide loyal customers with valuable information and experiences such as the real-time information of their farm and products, hidden stories about the whole process from seeding to harvesting, and the storage and cooking methods of their products. These activities help the producers invoke customers' desire to live in the farm and to grow the products themselves. They also raise the accessibility of the producers' websites as customers are able to share a variety of news and knowledge such as the release of new products. This means that the producers's websites are now functioning to enable the producers to perform sales and promotion related activities. It is a big leap from the traditional e-commerce business model where sales and promotion of a product were separated and could be connected only through outside links. This two-way, viral characteristics of marketing services using SNS facilitate customers to share product information and their purchase experience with each other, which leads to more effective and efficient communication within the customer community.

The effects of music therapy on vital signs and pulsatile oxygen saturation of pediatric intensive care unit children (음악을 이용한 간호중재가 중환자실 환아의 활력징후와 산소포화도에 미치는 영향)

  • Yoo Cheong-Suk;Song Kei-Hee
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.6 no.3
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    • pp.382-396
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    • 1999
  • This study was attempted to prove the effect of emotional stability and vital signs applying music therapy program to the children admitted in the PICU. Data were collected from July to September, 1997. The subjects were 30 patients admitted in the PICU of 'S' University Hospital which were divided into two groups of experimental and control. Each group had 15 subjects. Method was nonequivalent control group pretest-postteset repeated design, observing vital signs and activity of subjects prior, during, and after the music intervention. The study tools were cassette tapes of 'Mother's music whose babies want to listen' and Space-lab patient monitor. Data were analyzed using the $SPSS/PC+;x^2$ test and t-test to analyze of the general characteristics ; paired t-test to prove hypotheses. Result were as follows; 1. Infants lower than seven months showed changing into stable vital signs from applying the music therapy, however infants from eight months to three-year old showed no change in vital signs. 2. Vital signs changed to stabilized condition in infants lower than seven months were heart rate and respiration rate. 3. The stability of vital signs during music therapy turned back to the previous state while terminating music therapy. 4. The effect of music therapy in the state of activity had on both infants group of lower than seven months and from eight months to three-year old, particularly more effective in the later group. I recommend follows on the base of above results ; 1. As above results shows, listening to music is effective on infants and toddler, intervention with music therapy appropriate to chidlren's age is hot recommended. 2. Comparative study with noise blocking effect and music therapy effect within the ICU environment be recommended. 3. The repeated study on when the exact time is and how many repeat the music therapy to show the above mentioned effect be recommended. 4. We recommend this music therapy to be done in the recovery room, isolating room, operating room as well as ICU.

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Implementation about measurement of the head SAR and variable parameter according to operation control mode in brain MR study with 1.5Tesia (1.57 BRAIN MRI검사에서의 작동제어모드를 통한 두부 SAR측정과 변화인자에 관한 고찰)

  • Lee, Kyu-Su;Sim, Hyun;Moon, Ji-Hoon;Oh, Jae-Cheol
    • Proceedings of the KIEE Conference
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    • 2007.04a
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    • pp.58-60
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    • 2007
  • Magnetic Resonance Imaging(MRI) has become a very widely used medical procedur e. Clo.sed and open systems are typically used with static magnetic fields at or below 2 Tesla. BWhole body SAR(specific absorbsion rate) is the value of SAR averaged over the entire body of the patient over any period of 15 minutes. Head SAR is the value of SAR averaged over the head of the patient for any period of 10 minutes. SAR is a measure of the absorption of electromagnetic energy in the body' (typically in watts per kilogram (W/kg)). The normal operating mode comprises values of head SAR not higher than 3 W/kg. The second level controlled operating mode comprises values higher than 3 W/kg. Current FDA guidance limits the SAR in the whole body. including the head to a range of 1.5 to 4.0 W/kg, depending on the patient's clinical condition. SAR, limit restrictions are incorporated in all MRI systems. and domestic' s guidance limits the SAR in a part body. including the head to 3.2w/kg and less. The purpose of this study is to evaluate on change of head SAR in using MRI pulse sequence and to check if exceed 3.2(w/kg) level in domestic a part exposure through measured head SAR. 23 patient's the average head SAR of pulse sequence is that T2WI sagittal is 0.5375. T2WI axial(FSE) is 0.4817, T1WI axial(SE) is, 0.8179. FLAIR axial is 0.4580. GRE axial is 0.0077, Diffusion is 0.0824w/kg. The head SAR exposed per patient was proved 2.3845w/kg less than the international standard. Coefficient of correlation for the relations body weight and SAR or for the relations ETL(echo train length) and SAR is 1 value. Coefficient of correlation for the relations between TR(time to repeat) and SAR is -0.602 value. so SAR increased relative to weight body and ETL. But the relations between TR and SAR is negative definite.

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A study about pattern and symbol shown in the mural painting of Koguryo dynasty's tomb (고구려(高句麗) 고분벽화(古墳壁畵)에 나타난 문양(紋樣)과 상징성(象徵性)에 관(關)한 고찰(考察))

  • Choe, Hye-Jeong
    • Journal of the Korean Society of Costume
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    • v.13
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    • pp.51-72
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    • 1989
  • In this thesis, I examined the mental, philosophical aspects and the aesthetic sense of our ancestors through the study of the patterns pictured in the mural paintings of Koguryo dynasty's old tomb. To view the mode of construction in Koguryo dynasty from present angle, the detailed analysis of the patterns was done. As a result, I could fully understand the formative consciousness of our nation. 1. I defined the process of transition of the mural paintings by putting some 70 mural aintings into the form of a diagram. 2. The cultural aspects of the mural paintings in Koguryo dynasty were characterized by the fusion of our primitive religion and Buddhism, Confucianism and Taoism which were introduced from China. From this fact, I could inferred that Koguryo people were giving off the strong desire for the faith by means of the mural paintings. Further more I found that configuration of the patterns such as religious elements. 3. The types of the patterns were classified into four types, this is, geometric type, natural type, cultural type and abstract type, Among these types, geometric type and natural type were nonsymbolic in nature but became cultured and abstracted in course of time. cultural pattern and abstract pattern got the symbolic meaning in the long run. Of all the constitution of the patterns represented in the mural paintings such as repeat constitution, left and right symmetric constitution, top and bottom symmetric constitution and rotary symmetric constitution, the left and right symmetric constitution was mainly used and some monotony of left and right symmetric constitution. The analysis of motif which was got from the mode of the patterns showed that the mixing of symbolic and nonsymbolic patterns made it possible to regard the separate symbol as compound in nonsymbolic patterns and the combination between nonsymbolic patterns ensured the understanding of other patterns in certain cases. Our ancestors made great efforts to transmit certain meaning symbolically. Also to heighten the symbolism, they drew the meangless patterns firstly and then appended meaning to those patterns secondly. Furthermore, they offered the background to the patterns comblined with symbolism, so that meaning transmission was clarified at last. As mentioned above, the patterns shown in the mural paintings of Koguryo dynasty's old tomb were characterized by natural beauty. And natural beauty was found out clearly in the form and constitution of the patterns. Therefore I concluded that our nation's religious, philosophical tradition was acted on the patterns strongly.

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Severity and Characteristics of Speeding Offenders at Signalized Intersection (신호교차로의 과속운전자 특성 및 심각도 분석)

  • PARK, Jeong Soon;OH, Ju Taek;CHO, Kyu Chul
    • Journal of Korean Society of Transportation
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    • v.35 no.1
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    • pp.11-24
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    • 2017
  • Although many efforts to stop speeding or inappropriate speed, it failed to reduce the number of speeding-related crashes. Therefore, it is important to analyze the characteristics of speeding offenders and the cause of speeding at hot spots. In this study, we investigate the level of severity in speeding by the characteristics of speeding offenders using the Ordered Logistics Regression Models(OLRM). For the analysis, we use the speeding data collected by 39 traffic enforcement cameras in city of Cheongju and other related data including the speeding ticket history of drivers during the most recent 3 years, their demographic characteristics, their own vehicles, and road environment factors. The major results of this study are as follows. Firstly, commercial fleet drivers are more likely to repeat the conviction of high-range speeding with more than 30km/h over speed limits than other drivers. Secondly, mid-range speeding are observed as 21,462 frequency which is 76.7% of total speeding frequency and occurred mostly at suburban and rural area. It concludes that contributory factors affecting the severity of speeding at signalized intersection are drivers' speeding offence history, posted speed limits, time of day, gender of driver, and location of the intersection as show by the OLRM developed in this study(McFadden R-square : 0.296).

A Study of Driver's Response to Variable Message Sign Using Evolutionary Game Theory (진화 게임을 이용한 VMS 정보에 따른 운전자의 행태 연구)

  • Kim, Joo Young;Na, Sung Yong;Lee, Seungjae;Kim, Youngho
    • Journal of Korean Society of Transportation
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    • v.32 no.5
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    • pp.554-566
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    • 2014
  • An objective of VMS(Variable Message Signs) is to make transportation system effective specifically for driver's path selection. The traffic solutions including a VMS problem can be modeled through Game Theory, however, the majority of the studies can not model various driver's response according to VMS information in game theory. So, this paper tries to analyze a driver's response according to VMS traffic informations through evolutionary game theory. We apply a behavior characteristics of driver to evolutionary game theory, then finds drivers are only accepting in case of the biggest pay-off, and if a traffic flow finds a balance over time, ratio of accepting information is converged as an evolutionary stable state gradually. Consequently, the strategy of the other drivers such as traffic problems can not be predicted accurately. In case, drivers repeat between groups and reasonable judgment by the experience, we expect that VMS can provide strategic information through evolutionary game theory.