• Smart Structures and Systems
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• 제21권6호
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• pp.741-749
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• 2018

Structural health monitoring (SHM) systems are necessary to achieve smart predictive maintenance and repair planning as well as they lead to a safe operation of mechanical structures. In the context of vibration-based SHM the measured structural responses are employed to draw conclusions about the structural integrity. This usually leads to a mathematically illposed inverse problem which needs regularization. The restriction of the solution set of this inverse problem by using prior information about the damage properties is advisable to obtain meaningful solutions. Compared to the undamaged state typically only a few local stiffness changes occur while the other areas remain unchanged. This change can be described by a sparse damage parameter vector. Such a sparse vector can be identified by employing $L_1$-regularization techniques. This paper presents a novel framework for damage parameter identification by combining sparse solution techniques with an Extended Kalman Filter. In order to ensure sparsity of the damage parameter vector the measurement equation is expanded by an additional nonlinear $L_1$-minimizing observation. This fictive measurement equation accomplishes stability of the Extended Kalman Filter and leads to a sparse estimation. For verification, a proof-of-concept example on a quadratic aluminum plate is presented.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2002년도 Proceedings of the International Welding/Joining Conference-Korea
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• pp.668-674
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• 2002

Structural integrity assessment is indispensable for preventing catastrophic failure of industrial structures/components/facilities. This diagnosis of operating components should be done periodically for safe maintenance and economical repair. However, conventional standard methods for mechanical properties have the problems of bulky specimen, destructive and complex procedure of specimen sampling. Especially, the mechanical properties at welded zone including weldment and heat affected zone could not be evaluated individually due to their size requirement problem. So, an advanced indentation technique has been developed as a potential method for non-destructive testing of in-field structures. This technique measures indentation load-depth curve during indentation and analyzes the mechanical properties related to deformation such as yield strength, tensile strength and work-hardening index. Also indentation technique can evaluate a residual stress based on the concept that indentation load-depth curves were shifted with the direction and the magnitude of residual stress applied to materials. In this study, we characterized the tensile properties and welding residual stress of various industrial facilities through the new techniques, and the results are introduced and discussed.

• Corrosion Science and Technology
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• 제11권5호
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• pp.173-178
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• 2012

To manage the wall thinning of carbon steel piping in nuclear power plants, the utility of Korea has performed thickness inspection for some quantity of pipe components during refueling outages and determined whether repair or replacement after evaluating UT (Ultrasonic Test) data. When the existing UT data evaluation methods, such as Band, Blanket, PTP (Point to Point) Methods, are applied to a certain pipe component, unnecessary re-inspecting situations may be generated even though the component does not thinned. In those cases, economical loss caused by repeated inspection and problems of maintaining the pipe integrity followed by decreasing of newly inspected components may be generated. EPRI (Electric Power Research Institute) in USA has suggested several statistical methods, TPM (Total Point Method), LSS (Least Square Slope) Method, etc. to distinguish whether multiple inspecting components have thinned or not. This paper presents the analysis results for multiple inspecting components over three times based on both NAM (Near Area of Minimum) Method developed by KEPCO-E&C and the other methods suggested by EPRI.

• 대한의생명과학회지
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• 제17권2호
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• pp.167-171
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• 2011

[ ${\alpha}$ ]synuclein (${\alpha}$-syn) is implicated in the pathogenesis of Parkinson's disease (PD) and other related diseases. We have previously reported that ${\alpha}$-syn binds to the cell membranes in a transient and reversible manner. However, little is known about the physiologic function and/or consequence of this association. Here, we examined whether chemically induced perturbations to the cellular membranes enhance the binding of ${\alpha}$-syn, based on hypothesis that ${\alpha}$-syn may play a role in maintenance of membrane integrity or repair. We induced membrane perturbations or alterations in ${\alpha}$-syn-overexpressing human neuroblastoma cells (SH-SY5Y) by treating the cells with hydrogen peroxide ($H_2O_2$) or oleic acid. In addition, membranes fractionated from these cells were perturbed by treating them with proteinase K or chloroform. Dynamic interaction of ${\alpha}$-syn to the membranes was analyzed by the chemical cross-linking assay that we developed in the previous study. We found that membrane interaction of ${\alpha}$-syn was increased upon treatment with membrane-perturbing reagents in a dose and time dependent manner. These results suggest that perturbations in the cellular membranes cause increased binding of ${\alpha}$-syn, and this may have significant implication in the physiological function of ${\alpha}$-syn in cells.

• Smart Structures and Systems
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• 제5권4호
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• pp.443-455
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• 2009

The use of fiber reinforced polymer (FRP) reinforcement in concrete structures has been on the rise due to its advantages over conventional steel reinforcement such as corrosion. Reinforcing steel corrosion has been the primary cause of deterioration of reinforced concrete (RC) structures, resulting in tremendous annual repair costs. One application of FRP reinforcement to be further explored is its use in RC frames. Nonetheless, due to FRP's inherently elastic behavior, FRP-reinforced (FRP-RC) members exhibit low ductility and energy dissipation as well as different damage mechanisms. Furthermore, current design standards for FRP-RC structures do not address seismic design in which the beam-column joint is a key issue. During an earthquake, the safety of beam-column joints is essential to the whole structure integrity. Thus, research is needed to gain better understanding of the behavior of FRP-RC structures and their damage mechanisms under seismic loading. In this study, two full-scale beam-column joint specimens reinforced with steel and GFRP configurations were tested under quasi-static loading. The control steel-reinforced specimen was detailed according to current design code provisions. The GFRP-RC specimen was detailed in a similar scheme. The damage in the two specimens is characterized to compare their performance under simulated seismic loading.

• 한국국방경영분석학회지
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• 제28권1호
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• pp.115-135
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• 2002

The limits of current DN(Defense networks), private and closed network, become to reality; for Example, high expense of construction and maintenance of networks, restriction of new subscribers on DN. Therefore, a network using web environment that reflect fast development of If and IS(Information Security) technology is demanded for MND. Meeting the requirement of reliable IS system and extension and improvement of DN using common network, we can reduce the expense to extend, maintain, repair DN, form the environment that makes military business cooperate better with civil company and government agency, advance implementing Defense computing and networking service for field small size units that was a exception of Defense digitalization. But it is essential to construct DN based on common network that there are security requisites; confidentiality, integrity, availability, efficiency, log, backup, restoration, that have to be realized at demanding level for IS. This thesis suggested four measurements; replacement DN with common network to resolve the requirements of building new network and improvement of performance for private DN, linkage with common network for new requirement, distribution of traffic using common network, configuration of DN using Internet and Proposed a refinement of IS management organization to treat security threat of common network flexibly, and LAN IS standard model of DN based on the web environment.

• BMB Reports
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• 제52권1호
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• pp.24-34
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• 2019

Sirtuin is an essential factor that delays cellular senescence and extends the organismal lifespan through the regulation of diverse cellular processes. Suppression of cellular senescence by Sirtuin is mainly mediated through delaying the age-related telomere attrition, sustaining genome integrity and promotion of DNA damage repair. In addition, Sirtuin modulates the organismal lifespan by interacting with several lifespan regulating signaling pathways including insulin/IGF-1 signaling pathway, AMP-activated protein kinase, and forkhead box O. Although still controversial, it is suggested that the prolongevity effect of Sirtuin is dependent with the level of and with the tissue expression of Sirtuin. Since Sirtuin is also believed to mediate the prolongevity effect of calorie restriction, activators of Sirtuin have attracted the attention of researchers to develop therapeutics for age-related diseases. Resveratrol, a phytochemical rich in the skin of red grapes and wine, has been actively investigated to activate Sirtuin activity with consequent beneficial effects on aging. This article reviews the evidences and controversies regarding the roles of Sirtuin on cellular senescence and lifespan extension, and summarizes the activators of Sirtuin including Sirtuin-activating compounds and compounds that increase the cellular level of nicotinamide dinucleotide.

• Structural Monitoring and Maintenance
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• 제10권3호
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• pp.221-242
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• 2023

Internal and external corrosion are common in pressure pipes used in a variety of industries, often resulting in defects that compromise their integrity. This economically and industrially significant problem calls for both preventive and curative technical solutions to guarantee the reliability of these structures. With this in mind, our study focuses on the influence of composite and metallic patch repairs on the limit loads of pipes, particularly elbows, the critical component of piping systems. To this end, we used the nonlinear extended finite element method (X-FEM) to study elbows, a priori corroded on the internal surface of the extrados section, then repaired with composite and metallic patches. In addition, the effect of the geometry of composite materials and metal patches was examined, in particular the effect of their thickness and material on the increase in limit loads of repaired structures. The results obtained provide information on the effectiveness and optimization of patch repair of corroded elbows, with the aim of increasing their service life.

• Geomechanics and Engineering
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• 제37권1호
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• pp.21-29
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• 2024

The effective management of damage in tunnels is crucial for ensuring their safety, longevity, and operational efficiency. In this paper, we propose an educational management model tailored specifically for addressing damage in tunnels, utilizing numerical solution techniques. By leveraging advanced computational methods, we aim to develop a comprehensive understanding of the factors contributing to tunnel damage and to establish proactive measures for mitigation and repair. The proposed model integrates principles of tunnel engineering, structural mechanics, and numerical analysis to facilitate a systematic approach to damage assessment, diagnosis, and management. Through the application of numerical solution techniques, such as finite element analysis, we demonstrate the efficacy of the proposed model in simulating various damage scenarios and predicting their impact on tunnel performance. Additionally, the educational component of the model provides valuable insights and training opportunities for tunnel management personnel, empowering them to make informed decisions and implement effective strategies for ensuring the structural integrity and safety of tunnel infrastructure. Overall, the proposed educational management model represents a significant advancement in tunnel management practices, offering a proactive and knowledge-driven approach to addressing damage and enhancing the resilience of tunnel systems.

• 대한정형외과 초음파학회지
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• 제1권2호
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• pp.78-85
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• 2008

목적: 회전근 개 파열 환자에서 수술 전의 자기 공명 영상 검사와 초음파 검사에 따른 관절경 소견을 비교하고, 수술 후 2주, 6주 및 3개월의 회전근 개의 건재 상태를 초음파로 확인하는데 있다. 대상 및 방법: 2008년 2월부터 5월까지 본원 정형외과에 내원하여 회전근 개 파열로 관절경적 치료를 시행한 환자 29명을 대상으로 초음파 검사와 자기 공명 영상 검사를 시행한 후 관절경적 시술을 이용하여 비교하였으며, 수술 후 2주, 6주 및 3 개월에 회전근 개의 건재 상태를 초음파를 이용하여 관찰하였다. 결과: 회전근 개 파열을 확인할 수 있는 초음파 검사와 자기 공명 영상 검사의 예민도는 각각 100%였다. 전층 회전근 개 파열에서 초음파 검사와 자기 공명 영상 검사의 예민도는 각각 95%, 82%였으며, 부분층 회전근 개 파열에서 초음파 검사는 50%, 자기 공명 영상 검사는 33%의 예민도를 나타내었다. 전체 환자에 대한 초음파 검사의 정확도는 86%, 자기 공명 영상 검사의 정확도는 69%이었다. 전층 회전근 개 파열로 복원술을 시행한 22예 중 수술 후 2주에 시행한 추시 관찰 초음파 검사상 11예(50%, 소 및 중 파열 2예, 대 및 광범위 파열 9예)에서 회전근 개의 봉합 부위에서 수술 소견과 일치하는 틈새로 진단되는 저에코를 확인할 수 있었으며, 수동적 신장 운동을 시행한 후 수술 6주의 추시 관찰 초음파 검사상 5예(23%, 소 및 중 파열 1예, 대 및 광범위 파열 4예)에서 재파열 소견을, 능동적 운동을 시행한 후 수술 3개월의 추시 관찰 초음파 검사상 7예(32%, 소 및 중파열 2예, 대 및 광범위 파열 5예)에서 재파열 소견을 보였다. 결론: 회전근 개 파열에 대한 관절경적 치료 후 초음파 연속 검사는 술 후 틈새와 술 후 재파열을 구분하는데 도움을 줄 수 있었으며, 수술 후 6주에 23%, 3개월에 32%의 재파열 소견을 보인 바 재활 치료시 추가 치료의 방침을 세우는데 도움을 줄 수 있을 것으로 생각되었다.