• 대한공업교육학회지
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• 제34권1호
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• pp.87-112
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• 2009

이 연구의 목적은 방송 산업 분야의 특성화고등학교로 전환을 위한 S특성화 방송고등학교의 실험 실습실 재구조 방안과 리모델링 모형 및 방향을 제시하는 것이다. 각 과별로 실험 실습실 재구조 방안은 첫째, 각 전공별로 개편할 실습실명과 평면도 및 투시도를 구성주의 철학에 맞도록 재구성 설계하였다.둘째, 과별로 주요 실험 실습실 개편에서 방송기계과에서는 방송무대기계실습실, 방송기계요소가공실, 방송기계설비실습실, 영상기계실습실 등, 방송전기통신과에서는 영상 음향편집실, 방송통신설비실, 방송시스템실습실, 무대조명실습실 등, 방송무대건축과에는 방송무대제작실습실, 방송무대디자인 실습실, 방송무대장식실습실 등 각과별로 7실을 제안하였다. 셋째, 과별 사무실을 세미나실로 배치하였고, 각 실습장은 전공별 전담제로 실습실 관리 및 연구실화하는 방향으로 설계하였다. 넷째, 과별로 산학협력실을 설치하여 외부의 기업체가 입주시켜 산학협력교육이 원활하게 이루어 질 수 있도록 산학 연계 교육의 장으로 구상하였다. 그리고 각 과별로 실험 실습장 1실에 대하여 개편 실습실명, 평면도 및 투시도, 실습실 운용 방안 등을 예를 들어 제시하였다. 특히 방송 관련 실험 실습실 운영을 효율적으로 하기 위해서는 산학겸임교사 활용, 방송기술관련 전문 동아리, 학교내 기업 유치 등을 중요한 요인으로 제시하였다. 끝으로 방송 산업 분야의 특성화고등학교로 성공하기 위한 실험 실습실 리모델링 및 장비 구입에 많이 예산이 소요되는 분야이므로 '민간자본유치사업(BTL)'을 유치하는 것도 바람직하다.

• 한국농촌건축학회논문집
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• 제16권4호
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• pp.67-74
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• 2014

Departmentalized Classroom System is new school operating system to apply social needs. Recent social needs are characterized as learning environment and self-learning system. The purpose of this study is to provide basic data for equal learning environment condition in middle school applying departmentalized classroom system. This study has progressed through analyzing on 11 remodelling case of middle school in Gangwon-Do. The method of this study is visiting middle schools that operate the system, grasping the condition for environment composition, and investigating and analyzing practical use of the environment. The results of this study are summarized as follows: 1) The space compositions for departmentalized classroom system are generally desirable, but some schools take irrational space composition, especially on home base-teacher laboratory, classroom-teacher laboratory. 2) The space area distributions are different in every school. This result is based on not taking standard criterion on space area distribution.

• 식물조직배양학회지
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• 제27권5호
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• pp.359-366
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• 2000

Epigenetics represents a chromatin-mediated transcriptional repression which plays a control role in both animal and plant development. A number of different mechanisms have been described to be involved in the formation of chromatin structure: especially DNA methylation, nucleosomal histone modification, DNA replication timing, and binding of chromatin remodelling proteins. Epigenetic phenomena include genomic imprinting, dosage compensation of X-chromosome linked genes, mutual allelic interactions, paramutation, transvection, silencing of invasive DNA sequences, etc. They are often unstable and inherited in a non-Mendelian way. A number of epigenetic defects has been preferentially described in floral development. Here, epigenetic phenomena in model angiosperm plants and their corresponding mechanisms are reviewed.

• 한국농촌건축학회논문집
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• 제17권4호
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• pp.83-90
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• 2015

The equalization policy needs various factors-standardization of educational environment, standardization of learning method, standardization of teacher ability, etc. Especially the standardization of educational environment is the base of various factors. But the recent educational environment condition of high school is not equal. The purpose of this study is to provide basic data for equal learning environment condition in high school applying departmentalized classroom system. This study has progressed through analyzing on 9 remodelling case of high school in Gangwon-Do. The method of this study is visiting high schools that operate the system, grasping the condition for environment composition, and investigating and analyzing practical use of the environment. The results of this study are summarized as follows: 1) The space compositions for departmentalized classroom system are generally desirable, but some schools take irrational space composition, especially on home base-teacher laboratory, classroom-teacher laboratory. 2) The space area distributions are different in every school. This result is based on not taking standard criterion on space area distribution.

• 대한임상검사과학회지
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• 제49권4호
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• pp.337-344
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• 2017

To date, no clear threshold that has been established for defining an adequate store of vitamin D for bone health. Therefore, this study aims to determine the required level of vitamin D to maintain a healthy skeleton based on bone remodelling process among healthy adult population. This was a cross sectional study, involving a healthy adult population in Kota Bharu, Malaysia, aged 18~50 years. We measured serum 25(OH)D (vitamin D), serum parathyroid hormone (PTH), serum C-terminal telopeptide of type 1 collagen (CTX), and Procollagen 1 Intact N-Terminal (P1NP) in 120 healthy adults selected via multi stage sampling (64 males, 56 females) from 6 subdistricts in Kota Bharu. The mean level of 25(OH)D was 23.50 (${\pm}8.74$) nmol/L. There was a significant difference of the vitamin D level between genders ($26.81{\pm}8.3nmol/L$ vs $19.72{\pm}7.68nmol/L$ in males and females respectively) (p value<0.001). More than 50% of female subjects had 25(OH)D less than 20 nmol/L, while only 20.3% of male subjects had 25(OH)D below 20 nmol/L. Based on the LOESS plot, the bone turnover markers showed a plateauing result, at the 25(OH)D level of 35 nmol/L for CTX and 20 nmol/L for P1NP. Contrastingly, PTH showed a step rise in the 25(OH)D level of 20 nmol/L. Based on the LOESS plot for CTX, P1NP and PTH versus 25(OH)D, level of vitamin D between 20 to 35 nmol/L is recommended to maintain healthy skeleton.

• Asian Pacific Journal of Cancer Prevention
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• 제15권15호
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• pp.6429-6436
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• 2014

Poly-ADP-ribosylation (PAR) is a post-translational modification of mainly chromosomal proteins. It is known to be strongly involved in several molecular events, including nucleosome-remodelling and carcinogenesis. In this investigation, it was attempted to evaluate PAR level as a reliable biomarker for early detection of cancer in blood lymphocyte histones. PAR of isolated histone proteins was monitored in normal and dimethylnitrosamine (DMN)-exposed mice tissues using a novel ELISA-based immuno-probe assay developed in our laboratory. An inverse relationship was found between the level of PAR and period of DMN exposure in various histone proteins of blood lymphocytes and spleen cells. With the increase in the DMN exposure period, there was reduction in the PAR level of individual histones in both cases. It was also observed that the decrease in the level of PAR of histones resulted in progressive relaxation of genomic DNA, perhaps triggering activation of genes that are involved in initiation of transformation. The observed effect of carcinogen on the PAR of blood lymphocyte histones provided us with a handy tool for monitoring biochemical or physiological status of individuals exposed to carcinogens without obtaining biopsies of cancerous tissues, which involves several medical and ethical issues. Obtaining blood from any patient and separating blood lymphocytes are routine medical practices involving virtually no medical intervention, post-procedure medical care or trauma to a patient. Moreover, the immuno-probe assay is very simple, sensitive, reliable and cost-effective. Therefore, combined with the ease of preparation of blood lymphocytes and the simplicity of the technique, immuno-probe assay of PAR has the potential to be applied for mass screening of cancer. It appears to be a promising step in the ultimate goal of making cancer detection simple, sensitive and reliable in the near future.