• Title/Summary/Keyword: Reliability-Reproducibility of Results

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Applicability of the digital instrument to improve the reproducibility of motor unit number index

  • Ahn, Suk-Won
    • Annals of Clinical Neurophysiology
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    • v.20 no.1
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    • pp.26-30
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    • 2018
  • Background: The motor unit number index (MUNIX) and motor unit size index (MUSIX) refer to the electrophysiological measurement of the motor units using the surface electromyographic interference pattern (SIP) recorded during graded muscle contraction. In order to improve the reliability and reproducibility of MUNIX by the systematization of the graded muscle contractions, we applied a digital hand instrument to the procedure of recording SIP signals. Methods: We tested the applicability of the digital instrument in the MUNIX technique by assessing the mean values and the reproducibility of the MUNIX involving the abductor pollicis brevis (APB) and the abductor digiti minimi (ADM) muscles in 30 healthy adults. Results: The digital dynamometer was successfully applied to the MUNIX measurements of the APB and ADM muscles, and showed high reproducibility across trials. Conclusions: Application of the digital instrument would be useful in improving the reliability and reproducibility of MUNIX.

Reproducible Chemical Mechanical Polishing Characteristics of Shallow Trench Isolation Structure using High Selectivity Slurry

  • Jeong, So-Young;Seo, Yong-Jin;Kim, Sang-Yong
    • Transactions on Electrical and Electronic Materials
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    • v.3 no.4
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    • pp.5-9
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    • 2002
  • Chemical mechanical polishing (CMP) has become the preferred planarization method for multilevel interconnect technology due to its ability to achieve a high degree of feature level planarity. Especially, to achieve the higher density and greater performance, shallow trench isolation (STI)-CMP process has been attracted attention for multilevel interconnection as an essential isolation technology. Also, it was possible to apply the direct STI-CMP process without reverse moat etch step using high selectivity slurry (HSS). In this work, we determined the process margin with optimized process conditions to apply HSS STI-CMP process. Then, we evaluated the reliability and reproducibility of STI-CMP process through the optimal process conditions. The wafer-to-wafer thickness variation and day-by-day reproducibility of STI-CMP process after repeatable tests were investigated. Our experimental results show, quite acceptable and reproducible CMP results with a wafer-to-wafer thickness variation within 400$\AA$.

Reproducibility of Statistical Motor Unit Number Estimate in Amyotrophic Lateral Sclerosis: Comparisons between Size-and Number-Weighted Modifications (근위축성 측삭 경화증에서의 Statistical Motor Unit Number Estimate 재연성: Size-and Number-Weighted Modifications간의 비교)

  • Kwon, Oh Yun;Lee, Kwang-Woo
    • Annals of Clinical Neurophysiology
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    • v.5 no.1
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    • pp.27-33
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    • 2003
  • Background: Motor unit number estimation (MUNE) can directly assess motor neuron populations in muscle and quantify the degree of physiologic and/or pathologic motor neuron degeneration. A high degree of reproducibility and reliability is required from a good quantitative tool. MUNE, in various ways, is being increasingly applied clinically and statistical MUNE has several advantages over alternative techniques. Nevertheless, the optimal method of applying statistical MUNE to improve reproducibility has not been established. Methods: We performed statistical MUNE by selecting the most compensated compound muscle action potential (CMAP) area as a test area and modified the results obtained by weighted mean surface-recorded motor unit potential (SMUP). Results: MUNE measures in amyotrophic lateral sclerosis (ALS) patients showed better reproducibility with sizeweighted modification. Conclusions: We suggest size-weighted MUNE testing of "neurogenically compensated"CMAP areas present an optimal method for statistical MUNE in ALS patients.

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Mini-Review of Studies Reporting the Repeatability and Reproducibility of Diffusion Tensor Imaging

  • Seo, Jeong Pyo;Kwon, Young Hyeon;Jang, Sung Ho
    • Investigative Magnetic Resonance Imaging
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    • v.23 no.1
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    • pp.26-33
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    • 2019
  • Purpose: Diffusion tensor imaging (DTI) data must be analyzed by an analyzer after data processing. Hence, the analyzed data of DTI might depend on the analyzer, making it a major limitation. This paper reviewed previous DTI studies reporting the repeatability and reproducibility of data from the corticospinal tract (CST), one of the most actively researched neural tracts on this topic. Materials and Methods: Relevant studies published between January 1990 and December 2018 were identified by searching PubMed, Google Scholar, and MEDLINE electronic databases using the following keywords: DTI, diffusion tensor tractography, reliability, repeatability, reproducibility, and CST. As a result, 15 studies were selected. Results: Measurements of the CSTs using region of interest methods on 2-dimensional DTI images generally showed excellent repeatability and reproducibility of more than 0.8 but high variability (0.29 to 1.00) between studies. In contrast, measurements of the CST using the 3-dimensional DTT method not only revealed excellent repeatability and reproducibility of more than 0.9 but also low variability (repeatability, 0.88 to 1.00; reproducibility, 0.82 to 0.99) between studies. Conclusion: Both 2-dimensional DTI and 3-dimensional DTT methods appeared to be reliable for measuring the CST but the 3-dimensional DTT method appeared to be more reliable.

Evaluation of Reliability of Automatic System for Measuring Sizing Degree by Basis Weight Variation of Paper (종이 평량의 차이에 따른 자동 사이즈도 측정 시스템의 신뢰성 평가)

  • Lee, Ji-Young;Kim, Chul-Hwan;Lee, Ji-Young;Nam, Hye-Gyeong;Lee, Gyeong-Sun;Jo, Hu-Seung;Park, Hyung-Hun
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.46 no.3
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    • pp.11-19
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    • 2014
  • Reliability of the novel automatic system capable of measuring both St$\ddot{o}$ckigt sizing degree and contact angle at a time was evaluated through the calculation of its repeatability and reproducibility based on TAPPI Standard Method T 1200. As the basis weight of paper specimen increased, the repeatability and reproducibility of the automatic system became more improved than those from Hercules sizing test and contact angle test designated on TAPPI Standard Method T 530 and T 558. The more improved repeatability and reproducibility implies that a single tester can obtain the similar results under similar test conditions in spite of repetitive testing using the automatic system, and likewise that multiple testers can respectively reproduce similar data without big variation from the same paper specimen using the automatic system. In conclusion, this study is greatly meaningful in having developed the world's first automatic system to measure both St$\ddot{o}$ckigt sizing degree and contact angle simultaneously with excellent repeatability and reproducibility.

A STUDY ON THE DESIGN OF SIMPLE RECORDING DEVICE TO TRACE THE MANDIBULAR MOVEMENTS (하악골운동 추적을 위한 단순기록장치 고안에 관한 연구)

  • Kim, Sang-Soo;Yoon, Chang-Keun
    • The Journal of Korean Academy of Prosthodontics
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    • v.25 no.1
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    • pp.253-267
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    • 1987
  • The purpose of this study was to improve limitations and disadvantages of the mechanical pantograph and the Visi-Trainer, and to design the reliable and reproducible device mandibular movement tracking device (MMTD) that is more simple, convenient and save the chair time than the mechanical pantograph and Visi-Trainer. MMTD was consist of head frame, horizontal bar, condylar path tracking stylus holders, anterior path tracking stylus holder, two condylar path plastic recording plates, one anterior path plastic recording plate, toggles and open occlusal clutch. To prove the reliability and reproducibility of MMTD, a five adults were selected and mandibular condylar movement was recorded one time by the mechanical pantographic tracing and MMTD. The border movement recording of the mandibular incisor (frontal, sagittal and horizontal) was also recorded by Visi-Trainer and the MMTD. The obtained results were as follows; 1. The condylar movement path (sagittal, horizontal) of the MMTD was not coincidence with that of mechanical pantograph. 2. Measurements of the angulation which established between working and balancing path records by use of the mechanical pantograph and MMTD, there was no significance. 3. In a view of MMTD's reproducibility, there was revealed almost similar recording pattern. 4. The border movement recording of the mandibular incisor by the MMTD and the Visi-Trainer showed almost same reliability and reproducibility. 5. The subjects were able to his original mandibular movements by use of open occlusal clutch in the MMTD.

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Improvement of the repeatability and reproducibility of the meridian impedance measurement system MIR-2 (경락노선상 임피던스 측정기(MIR-2)의 측정신뢰도 개선방안 연구)

  • Yin, Chang-Shik;Lee, Hye-Jung;Kim, Jong-Yeol;Lee, Woo-Cheol
    • Korean Journal of Acupuncture
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    • v.24 no.4
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    • pp.55-67
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    • 2007
  • Objectives : The repeatability and reproducibility of MIR-2, a newly developed impedance measurement device (four electrode method) on skin are of the meridian system, is evaluated and a method to improve the reliability is discussed. Methods : Multiple gage R&R studies were conducted for the impedance measurements over bilateral KI3 acupoint in ten participants by three assessors using MIR-2 device. Gage R&R studies were repeated after controlling the acupoint locating method or one value correction by replacing one assessor's outlying value with an average of the other assessors' values to explore any feasibility of improvement of measurement reliability. Results : Controlling acupoint locating method and replacing one value with an average of other assessors' value led to improved variation metrics in a gage R&R study. Conclusions : Measurement reliability can be improved by controlling measurement procedures or by using repeated measurement method, which will facilitate development of clinically applicable measurement device with reliability.

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The Analysis on the Reliability of Measuring Pulse-Respiration Ratio (맥솔(脈率) 측정방법(測定方法)의 신뢰도(信賴度) 분석(分析))

  • Kim, Dong-Hoon;Yang, Dong-Hoon;Huh, Woong;Park, Young-Jae;Park, Young-Bae
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.9 no.2
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    • pp.123-144
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    • 2005
  • Objectives: Pulse-Respiration Ratio has been used for estimating subject's Han-Yeol [寒熱] status since it mentioned in suwen [素問]. In practicing Pulse-Respiration Ratio over 5 means the status of Yeol [熱], Pulse-Respiration Ratio below 3 means the status of Han [寒]. We performed this study to examine the Optimum Standard for Measuring Pulse-Respiration Ratio on the Basis of Repeatability and Reproducibility. Methods: After subject's 5 minutes rest we measured subject's ECG, respiration pattern, EEG, EMG simultaneously. In this research examiner's number is two, subject's number is four, and the number of repeat is two. We calculated Pulse-Respiration Ratio through dividing Respiration cycle average by Pulse cycle average according to each standard including time section, $EEG(relative-{\alpha}$ density, $relative-{\beta}$ density, ${\alpha}/{\beta}$ and EMG. We analyzed these data through Gage R&R study using MINITAB 13.20 program and considered the results of below 30 %R&R and over 4 Number of Distinct Categories to have a significance. Results: 1. In the applying of time standard, Pulse-Respiration Ratio from section 3, 4, 6, 8 had a significant meaning in the aspect of Repeatability and Reproducibility. 2. In the applying of $EEG({\alpha}$ I , ${\beta}$ I , ${\alpha}/{\beta})$, EMG(E I) standard, there was no significant results. 3. In the applying of time standard(section 5, 6, 7), $EEG({\alpha}$ I , ${\beta}$ I , ${\alpha}/{\beta})$ and EMG(E I) standard simultaneously, Pulse-Respiration Ratio from ${\alpha}/{\beta}$ in section 6, ${\beta}$ I in section 8 had a significant meaning in the aspect of Repeatability and Reproducibility. Conclusions: We can suggest the Optimum Standard for Measuring Pulse-Respiration Ratio on the basis of Repeatability and Reproducibility as followings; 1. Pulse-Respiration Ratio Measuring time should be at least 15 minutes. 2. Applying of time(section 6, 8) and $EEG({\beta}$ I, ${\alpha}/{\beta})$ standard simultaneously is recommended considering reliability and validity but more study is needed. 3. EMG(E I) may be helpful to detect the segment of physical rest and exclude artifacts but more study is needed.

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Comparison of the reproducibility of panoramic radiographs between dentulous and edentulous patients

  • Park, Jong-Woong;Huh, Kyung-Hoe;Yi, Won-Jin;Heo, Min-Suk;Lee, Sam-Sun;Choi, Soon-Chul
    • Imaging Science in Dentistry
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    • v.44 no.2
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    • pp.95-102
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    • 2014
  • Purpose: This study was performed to evaluate the reproducibility of panoramic radiographs of dentulous and edentulous patients. Materials and Methods: The reproducibility of panoramic radiographs was evaluated using the panoramic radiographs acquired from 30 anterior dentulous patients by using a common biting positioning device (dentulous group) and 30 anterior edentulous patients by using chin-support devices to take a panoramic radiograph (edentulous group), respectively; these patients had undergone 3 or more panoramic radiographs. The widths and angles between the designated landmarks were measured on the panoramic radiographs, and the reproducibility was evaluated using the intraclass correlation coefficient (ICC) and the coefficient of variation. Results: In the dentulous and edentulous groups, the ICCs of the mandibular ramus and mandibular angle areas were higher than the condylar head and zygomatic areas. The mandibular ramus and angle areas showed statistically lower mean coefficients of variation than the condylar head and zygomatic areas in the dentulous group. The mandibular angle area showed a significantly lower mean coefficient of variation than the zygomatic area in the edentulous group. By comparing the two groups, each ICC of the edentulous group was lower than that of the dentulous group, and the mean coefficients of variation of the mandibular ramus area, zygomatic area, left condylar inclination, and ramus ratio between the right and the left in the edentulous group were significantly higher than those in the dentulous group. Conclusion: Biting positioning for dentulous patients provided better positioning reproducibility than chin-support positioning when performing panoramic radiography for edentulous patients.

Study on Reliability of Interpretation and Reproducibility of a Pulse Analyser (맥진기 판독의 신뢰도 및 파형의 재현성 연구)

  • Park, Seung-Chan;Lee, Ji-Hye;Lee, Hye-Yoon;Cho, Min-Kyoung;Kim, Do-Hyung;Kim, So-Yeon;Choi, Jun-Yong;Han, Chang-Woo;Park, Seong-Ha;Hong, Jin-Woo;Lee, In;Kwon, Jung-Nam
    • The Journal of Internal Korean Medicine
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    • v.34 no.3
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    • pp.231-239
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    • 2013
  • Objectives : This study was performed to evaluate inter-rater and intra-rater reliability of interpretation and reproducibility of a pulse analyser (MAXMAC27-Plus). Methods : 38 of 40 volunteers completed the pulse analysis consecutively. Three Korean medical doctors who had at least 2 years of clinical experience interpreted the pulse waves for 3 aspects of size, depth and shape, then inter-rater reliability and crude agreement was obtained. Reinterpretation was done 2 weeks later and intra-rater reliability and crude agreement was obtained. Intra-rater reliability and crude agreement between 1st and 2nd measurement was calculated. Cohen's weighted kappa for size, Cohen's kappa for depth and shape were used as statistical analysis. Results : Inter-rater reliability of size, depth and shape among 3 raters was 0.598, 0.604, and 0.312, respectively, showing moderate to substantial agreement. Average intra-rater reliability between 1st and 2nd interpretation of size, depth and shape was 0.806, 0.705, and 0.638, respectively, showing substantial to almost perfect agreement. However, intra-rater reliability between consecutive measurements of size, depth and shape was 0.221, 0.121, and 0.194, respectively, which showed only poor to fair agreement. Conclusions : Intra-rater and inter-rater reliability of one pulse wave showed relatively high concordance. Training by a clinical expert may effect better concordance among raters. Test-retest reliability showed poor agreement. Improvement of measurement technique and device performance will be needed.