• The Journal of Korean Physical Therapy
• /
• v.31 no.3
• /
• pp.157-160
• /
• 2019

Purpose: We compared the activation pattern of the mirror neurons (MN) between two types of hand movement according to action observation using functional MRI. Methods: Twelve right-handed healthy subjects (5 male and 7 female, mean age $21.92{\pm}2.02years$) participated in the experiment. During fMRI scanning, subjects underwent two different stimuli on the screen: 1) video clips showing repeated grasping and releasing of the ball via simple hand movement (SHM), and (2) video clips showing an actor performing a Purdue Pegboard test via complex hand movement (CHM). paired t-test in statistical parametric mapping (SPM) was used to compare the activation differences between the two types of hand movement. Results: CHM as compared with the SHM produced a higher blood oxygen level dependent (BOLD) signal response in the right superior frontal gyrus, left inferior and superior parietal lobules, and lingual gyrus. However, no greater BOLD signal response was found by SHM compared with CHM (FWE corrected, p<0.05). Conclusion: Our findings provided that the activation patterns for observation of SHM and CHM are different. CHM also elicited boarder or stronger activations in the brain, including inferior parietal lobule called the MN region.

• Journal of Korean Medical classics
• /
• v.32 no.1
• /
• pp.191-204
• /
• 2019

Objectives : Focusing on Wujutong's critiques for Xiebaisan misuse, this study investigates how Xiebaisan and its constituent drugs have historically been used by medical doctors and analyzes the disputes in the controversial context with a summary. Methods : The contents of Xiebaisan prescription were collected and examined from the past literature and medical database, and the issues related to the debate were examined by analyzing the contents. Results : In the results of exploring the opinions of medical doctors, in general, Xiebaisan and Sangbaipi, a major medicinal drug, were seen to play a role in the work of reinforcing and reducing. In particular, Ye Tianshi was used with cold and pungent medicine to Xiebaisan as a method of releasing heat with pungent medicine for acute fever in spring, and at the same time, care was taken to avoid depletion of secretion in the stomach. Conclusions : Wujutong's critique is that in early symptoms of viral infection, the misuse of Xiebaisan seems to emphasize the adverse effects of the illness. It is hoped that further research on Xiebaisan incremental medication will be conducted in the future to help clinical applications of Xiebaisan system medication.

• Research in Community and Public Health Nursing
• /
• v.32 no.2
• /
• pp.140-149
• /
• 2021

Purpose: This study aimed to identify factors (biological, psychological, interpersonal, and contextual factors) associated with the weight bias internalization of the Korean girls in early adolescence. Methods: This study used a cross-sectional design. Data was collected from 233 girls aged 12~14 years with a self-reported questionnaire. With multiple regression analysis, the factors associated with the weight bias internalization of the girls in early adolescence were analyzed. Results: Of psychosocial factors, fear to fat (anti-fat attitude) (β=.43, p<.001) was associated with the weight bias internalization of the girls in early adolescence. In addition, attachment with teachers (β=-.11, p=.029) of an interpersonal factor and perceived socio-cultural pressure regarding weight control (β=.34, p<.001) of a contextual factor were associated with the weight bias internalization of the girls in early adolescence. Conclusion: For releasing the weight bias internalization of the girls in early adolescence, decreasing anti-fat attitude and socio-cultural pressure regarding weight control should be primarily required through social efforts including community and school based interventions.

• Clinical and Experimental Reproductive Medicine
• /
• v.48 no.1
• /
• pp.1-10
• /
• 2021

In Korean women, a westernized lifestyle is associated with an increased risk of breast cancer. Fertility preservation has become an increasingly important issue for women with breast cancer, in accordance with substantial improvements in survival rate after cancer treatment. The methods of controlled ovarian hyperstimulation (COH) for fertility preservation in breast cancer patients have been modified to include aromatase inhibitors to reduce the potential harm associated with increased estradiol levels. Random-start COH and dual ovarian stimulation are feasible options to reduce the total duration of fertility preservation treatment and to efficiently collect oocytes or embryos. Using a gonadotropin-releasing hormone agonist as a trigger may improve cycle outcomes in breast cancer patients undergoing COH for fertility preservation. In young breast cancer patients with BRCA mutations, especially BRCA1 mutations, the possibility of diminished ovarian reserve may be considered, although further studies are necessary. Herein, we review the current literature on the practical issues surrounding COH for fertility preservation in women with breast cancer.

• Advances in Computational Design
• /
• v.7 no.3
• /
• pp.189-210
• /
• 2022

Deployable structures have the ability to shift from a compact state to an expanded functional configuration. By extension, reconfigurability is another function that relies on embedded computation and actuators. Linkage-based mechanisms constitute promising systems in the development of deployable and reconfigurable structures with high flexibility and controllability. The present paper investigates the deployment and reconfigurability of modular linkage structures with a pin and a sliding support, the latter connected to a linear motion actuator. An appropriate control sequence consists of stepwise reconfigurations that involve the selective releasing of one intermediate joint in each closed-loop linkage, effectively reducing it to a 1-DOF "effective crank-slider" mechanism. This approach enables low self-weight and reduced energy consumption. A kinematics and finite-element analysis of different linkage systems, in all intermediate reconfiguration steps of a sequence, have been conducted for different lengths and geometrical characteristics of the members, as well as different actuation methods, i.e., direct and cable-driven actuation. The study provides insight into the impact of various structural typological and geometrical factors on the systems' behavior.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.36 no.3
• /
• pp.27-41
• /
• 2023

Objectives : The purpose of this study is to analyze the trends of Korean medicine treatment on postherpetic neuralgia. Methods : Domestic databases(OASIS, KISS, RISS, KISTI, NDSL, KMbase) were used to search case studies related to Korean medical treatment of postherpetic neuralgia. Total 9 studies were selected. Results : A total 15 prescriptions were used 22 times in 14 cases. Among them, Sipjeondaebo-tang(十全大補湯) was the most frequently prescribed. Total 91 herbs were used and they were classified as tonifying and replenishing medicine(補益藥), exterior-releasing medicine(解表藥) and blood-activating and stasis-dispelling medicine(活血祛瘀藥) in the order of mostly used. In 8 studies, in addition to herbal medicine treatment, other Korean medicine treatments such as acupuncture, pharmacopuncture, moxibusiton, cupping therapy and external agents were performed at the same time. Most frequently used acupoints were 足竅陰(GB44) and 商陽(LI1). Conclusions : This is the first study to analyze the trends of Korean medicine treatment for postherpetic neuralgia. Although there are some limitations, this study is thought to be helpful in the domestic treatment of postherpetic neuralgia in the future.

• Journal of Sasang Constitutional Medicine
• /
• v.13 no.3
• /
• pp.1-7
• /
• 2001

We analyzed 45 types of herbal medicines for Soyangin, clinically applied in Dongyisoosebowon. In order to discover the standard of herbal classification for the Sasang constitutions, four concepts of Sasang Medicine were applied. These included 'Sadangron(theory of four groups)', 'Seungganggaehap(ascending-descending and gathering-dispersing)', 'Pyorihanyoul(exterior-interior and hot-cold)', and 'Hyungchiaekmi(fragrance, smell, bodily fluid and taste)'. According to these analyzing methods of herbal properties, we have reached the following conclusions: Herbal medicines for 'Soyangin' are characterized by descending energetics that reinforce the Yin Qi. The 'Exterior cold disease' is treated with herbs that descend the "Exterior Yin" in five ways: by releasing exterior, by resolving dampness, by clearing and transforming heat phlegm, by clearing heat, and by settling and calming the spirit. The 'Interior heat disease' is treated with herbs that raise the "Interior Yang" in three ways: by tonifying kidney Yin, by clearing heat, and by clearing heat and purging.

• The Journal of Internal Korean Medicine
• /
• v.44 no.5
• /
• pp.979-986
• /
• 2023

Objective: The purpose of this study is to report the case of intracranial germ cell tumor-induced central diabetes insipidus (CDI) in a child treated with Korean herbal medicine. Methods: A nine-year-old female patient diagnosed with intracranial germ cell tumor-induced CDI suffering from polyuria, polydipsia, and headache was hospitalized. Nocturia frequency and 24-hour urine volume were assessed. Results: The patient was treated with Korean medicine, including Nokyong-hwan. As a result of the 6-day inpatient treatment, nocturia frequency was decreased 3-4 times to 0-1 time, and 24-hour urine volume was decreased. Conclusion: Korean medicine, including Nokyong-hwan, may be considered an optional treatment for releasing the symptoms of intracranial germ cell tumor-induced CDI. Further studies are needed to confirm this finding.

• The korean journal of orthodontics
• /
• v.36 no.5
• /
• pp.360-368
• /
• 2006

Objective: Surface characteristics of dental materials play an important role in bacterial adhesion. The purpose of this study was to investigate surface characteristics of 5 different light-cured orthodontic adhesives (1 fluoride-releasing composite, 3 non-fluoride-releasing composites, and f resin-modified glass ionomer). Methods: Surface roughness was measured using a confocal laser scanning microscope. Contact angle and surface free energy components were analyzed using the sessile drop method. Results: Surface roughness was significantly different between adhesives despite a relatively small variation (less than $0.05\;{\mu}m$). Lightbond and Monolok2 were rougher than Enlight and Transbond XT. There were also significant differences in contact angles and surface free energy components between adhesives. In particular, considerable differences in contact angles and surface free energy components were found between resin modified glass ionomer and the composites. Resin modified glass ionomer showed significantly smaller contact angles in 3 different probe liquids and had higher total surface free energy and stronger polarity, with notably stronger basic property than the composites. Conclusion: Resin modified glass ionomer may provide a more favourable environment for bacterial adhesion than composite adhesives.

• The korean journal of orthodontics
• /
• v.40 no.4
• /
• pp.260-266
• /
• 2010

Objective: The aim of this study was to determine whether different types of adhesive systems and enamel-protective agents will affect the tensile bond strength of lingual brackets. Methods: A total of 75 extracted mandibular incisors were randomly divided into 5 groups and lingual brackets were bonded. Group 1 specimens received Transbond XT (3M Unitek, Monrovia, CA, USA), Group 2 required the application of a fluoride-releasing resin (Ortho-coat, Pulpdent, Watertown, MA, USA) with Transbond XT, Group 3 specimens received a chlorhexidine varnish (Cervitec Plus, Ivoclar Vivadent, Schaan, Lichtenstein) with Transbond XT. In Group 4, a light-cured orthodontic adhesive (Aegis Ortho, Bosworth, Skokie, USA) was applied and in Group 5, an antimicrobial self-etching primer (Clearfil Protect Bond, Kuraray, Osaka, Japan) was used. Results: There were no significant differences in bond strength whether fluoride-releasing resin or chlorhexidine varnish were used or not. Group 5 had significantly higher bond strength and adhesive remnant index (ARI) values than other groups (p < 0.001). The application of enamel-protective products did not have an adverse affect on the bond strength of lingual brackets. Conclusions: These products might provide benefits both for the patient and the clinician, by supporting the oral hygiene during lingual orthodontic treatment. The higher ARI score may be beneficial for Clearfil Protect Bond but its excessive bond strength should be considered in clinical practice, especially where the enamel is thin.