• 한국화재소방학회논문지
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• 제32권6호
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• pp.28-33
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• 2018

건축물 구획공간에 따른 화재성상 및 열방출율을 측정하기 위하여 실물규모 침대 매트리스의 표준화재시험방법(KS F ISO 12949 : 2011)으로 화재시험을 수행하였다. 개방형공간과 구획공간 모두 버너착화 후 초기 약 3분까지는 유사한 화재성장의 경향을 보이는 것으로 확인되었다. 3분후 구획공간에서의 열방출율이 개방형 공간보다 증가되어 높은 것으로 확인되었다. 침대 매트리스(SS)의 경우, 개방형 공간에서의 최대열방출율은 735 kW이며, 구획공간에서의 최대열방출율은 992 kW 로 측정되었다. 침대 매트리스(Q)의 경우 3분후 구획공간에서의 열방출율이 개방형 공간보다 급격하게 증가되는 것으로 확인되었다. 개방형 공간에서의 최대열방출율은 1,087 kW, 이 때의 측정시간은 346s 이며, 구획공간에서의 최대열방출율은 2,127 kW, 이때의 측정시간은 287 s 측정되어 구획공간에 따른 최대열방출율 및 측정시간의 차이가 확인되었다.

• Journal of Pharmaceutical Investigation
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• 제31권2호
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• pp.101-106
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• 2001

Alginate-chitosan (anion-cationic polymeric complex) was prepared to control the release rate of silver sulfadiazine (AgSD). Na-alginate (2%) solution containing AgSD was gelled in $CaCl_2$ solution. The gel beads formed were immediately encapsulated with chitosan (CS). The gel matrix and membrane were then reinforced with chondroitin-6-sulfate (Ch6S). Release rate of AgSD from the gel matrix was investigated by placing alginate beads in the sac of cellulose membrane simmered in HEPES-buffer solution. The concentration of AgSD released was analyzed by UV at 264 nm. Incorporation capacity of AgSD in Ca-alginate gel was more than 90%. Alginate-Ch6S-CS could control the release rate of AgSD. The amount of AgSD release was dependent on the AgSD loading dose. Incorporation of tripolyphosphate (polyanionic crosslinker) onto the alginate-Ch6S-CS bead increased the release rate of AgSD. Collagen-coating had no influence on the AgSD release rate. Alginate-Ch6S-CS beads with a sufficiently high AgSD encapsulation were capable of controlling the release of the drug over 10 days. In summary, alginate-Ch6S-CS beads could be used as a sustained delivery for AgSD and provide local targeting with low silver toxicity and patient discomfort.

• 한국자동차공학회논문집
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• 제3권1호
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• pp.97-107
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• 1995

Global postbuckling analysis is accomplished for one-dimensional and two-dimensional delaminations. A new finite element model, which can be used to model the global postbuckling analysis of one-dimensional and two-dimensional delaminations, is presented. In order to calculate the strain energy release rate, geometrically nonlinear analysis is accomplished, and the incremental crack closure technique is introduced. To check the effectiveness of the finite element models and the incremental crack closure technique, the simplified closed-form sloution for a through-the-width delamination with plane strain condition is derived and compared with the finite element result. The finite element results show good agreement with the closed-foul1 solutions. The present method was extended to calculate the strain energy release rate for two-dimensional delamination. For a symmetric circular delamination, the strain energy release rate shows great variation along the delamination front. and the delamination growth appears to occur perpendicular to the loading direction.

• Journal of Pharmaceutical Investigation
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• 제11권3호
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• pp.14-20
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• 1981

One of the major objectives in the developments of a progesterone I.U.D. is to prepare devices which release drug at a constant rate for extended periods. A constant release rate is achived by maintaining drug concentration at a constant valve via the introduction of rate limiting membrane to solute diffusion at the surface of the devices. In this study, progesterone dispersed at monolithic device were prepared from polyhydroxy ethyl methacrylate. Constant release rate were obtained with device which were soaked in on ethanol-hexan solution. The release rate was dependant upon the concentration of the ethanolic solution in the soaking solution. This devices offer significant potential for futher development of hydrogel in the intrauterine contraception device for controlled release of progesterone.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2001년도 제16회 학술발표회 논문초록집
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• pp.1-6
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• 2001

In this paper, edge delaminations in cracked composite plates are analytically investigated. A theoretical model based upon a sub-laminate approach is used to determine the strain energy release rate, $G^{ed}$, in [$\pm$$\theta_m$/$90_n$]$_s$ carbon/epoxy laminates loaded in tension. The analysis provides closed-form expressions for the reduced stiffness due to edge delamination and matrix cracking and the total energy release rate. The parameters controlling the laminate behaviour are identified. It is shown that the available energy for edge delamination is increased notably due to transverse ply cracking. Also thermal stresses increase substantially the strain energy release rate and this effect is magnified by the presence of matrix cracking. Prediction for the edge delamination onset strain is presented and compared with experimental data. The analysis could be applied to ceramic matrix composite laminates where similar mechanisms develop, but further experimental evidence is required.

• Coupled systems mechanics
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• 제12권1호
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• pp.69-81
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• 2023

This paper considers a delamination analysis of a statically undetermined inhomogeneous beam structure of rectangular section with viscoelastic behavior under torsion. The beam is built in at its two ends. The beam has two longitudinal inhomogeneous layers with a delamination crack between them. A notch is made in the upper crack arm. The external torsion moment applied on the beam is a function of time. Under these conditions, the beam has one degree of indeterminacy. In order to derive the strain energy release rate, first, the static indeterminacy is resolved. Then the strain energy release rate is obtained by analyzing the balance of the energy with considering the viscoelastic behavior. The strain energy release rate is found also by analyzing the compliance of the beam for checkup. Solution of the strain energy release rate in a beam without a notch in the upper crack arm is derived too. In this case, the beam has two degrees of static indeterminacy (the torsion moment in the upper crack arm is treated as an additional internal redundant unknown). A parametric investigation of the strain energy release rate is carried-out.

• Archives of Pharmacal Research
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• 제15권2호
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• pp.162-168
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• 1992

Release characteristics of five different types of hydrophilic albumin microspheres (HAM) containing different ratios of methotrexate-albumin (MTX-HSA) conjugates to free MTX: 1 : 0 (HAMC), 3 :1 (HAMC 3F), 1 :1 (HAMCF), 1:3 (HAMCF3) and 0 : 1 (HAMF) were investigated in the absence or presence of protease using dissolution tester. In all the HAMs studied except HAMC, the MTX was released bi-exponentially in the absence of protease; an initial fast release period up to approximately 6h, and thereafter the release rate was very much slower. The fast release of MTX from the HAMs (such as HAMC3F, HAMCF, HAMCF3 and HAMF) at the initial phase in probably due to the release of "physically associated" MTX from the core of the HAMs. The initial rate constants were 7.2, 8.7, 8.5 and 5.9 times greater than the second rate constants for HAMF, HAMCF3, HAMCF and HAMC3F, respectively. MTX release from HAMC was very slow and mono-phasic. It was at most 2.2% of the total entrapped amount by 24 h. The protease accelerated the release of MTX from the HAMs. The percentages of MTX released from HAMs up to 24 h were 100, 89.0, 75.0, 66.0 and 61.0% for HAMF, HAMCF3, HAMCF, HAMC3F and HAMC, respectively in the presence of protease and the corresponding values in the absence of protease were 30.2 19.0, 10.0, 6.5 and 2.2%, respectively. In vitro release of MTX in the presence of protease varied according to the ratios of MTX-HSA conjugates to MTX; the data set from HAMF, HAMCF3 and HAMCF fits better to monophasic first-order profile more adequately than to zero-order profile, that of HAMC3 monophasic first-order, and that of HAMC to bi-phasic zero-order. Above results suggested that zero-order release rate can be achieved by adjusting the ratio of MTX-HSA conjugates to MTX in the preparation of HAMs such as HAMC3F.as HAMC3F.

• 한국농공학회지
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• 제36권2호
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• pp.44-55
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• 1994

This paper describes the development of real-time irrigation reservoir operation models that adequately allocate available water resources for paddy rice irrigation. Water requirement deficiency index(WRDI) was proposed as a guide to evaluate the operational performance of release schemes by comparing accumulated differences between daily release requirements for irrigated areas and actual release amounts. Seven reservoir release rules were developed, which are constant release rate method (CRR), mean storage curve method(MSC), frequency analysis method of reservoir storage rate(FAS), storage requirement curve method(SRC), constant optimal storage rate method (COS), ten-day optimal storage rate method(TOS), and release optimization method(ROM). Long-term forecasting reservoir operation model(LFROM) was formulated to find an optimal release scheme which minimizes WRDIs with long-term weather generation. Rainfall sequences, rainfall amount, and evaporation amount throughout the growing season were to be forecasted and the results used as an input for the model. And short-term forecasting reservoir operation model(SFROM) was developed to find an optimal release scheme which minimizes WRDIs with short-term weather forecasts. The model uses rainfall sequences forecasted by the weather service, and uses rainfall and evaporation amounts generated according to rainfall sequences.

• 한국임상약학회지
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• 제1권1호
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• pp.23-30
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• 1991

The sustained-release beads containing terbutaline sulfate (TBS) were prepared by rotogranulation method. The drug was dusted on the non-pareil seeds in a CF-granulator. The sustained-release beads were obtained by coating the active beads with ethylcellulose or $Eudragits^{(R)}$, using in any case the same granulator employed for active beads preparation. The release characteristics of sustained-release beads were examined in vitro by rotating basket method applied to $Bricanyl^{(R)}$ durules which is a sustained-release TBS matrix tablet. The release of terbutaline from the beads in vitro was first-order, and the release rate was dependent on both the coat weight ratio and membrane hydrophilicity. Both surfaces of the beads before and after dissolution were smooth. The drug release pattern from the beads could be thought the diffusion through the polymer membrane. The release rate and the surface of the beads stored for 3 years at room temperature were the same with those of the initial beads.

• 동력기계공학회지
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• 제11권1호
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• pp.51-55
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• 2007

A study on combustion characteristics using emulsified fuel in a diesel engine were performed experimentally. In this paper, the experiments were performed at engine speed 1800rpm, emulsion ratios were 0%, 10%, 20%, and main measured items were specific fuel consumption, cylinder pressure, rate of pressure rise, rate of heat release etc. The obtained conclusions were as follows. 1) Specific fuel consumption increased maximum by 19.8% at low load, but was not affected at full load. 2) Rate of pressure rise and rate of heat release were about the same in the case of 10% and 20% of emulsion ratio. 3) Cylinder Pressure increased 9.6%, rate of pressure rise increased 53.4% in case of emulsion ratio 20% at full load. 4) Rate of heat release increased 72.4% in case of emulsion ratio 20% at full load.