• IE interfaces
• /
• v.19 no.2
• /
• pp.97-105
• /
• 2006

In this paper, based on the process analysis of a semiconductor company, a lot order release procedure (input regulation) is developed for a semiconductor company. The major characteristic of the order release procedure in this paper is to consider the workloads of machines which are obtained from a virtual lot flows by the dispatching rule at machines in the shop of the semiconductor company. The objective is to minimize the cycle time and to obtain other good performances. A simulation is performed in order to evaluate the order release procedure in this paper.

• Biomedical Science Letters
• /
• v.7 no.3
• /
• pp.127-131
• /
• 2001

This study was undertaken to examine the effect of amino acids on anoxia-induced cell injury in rabbit renal cortical slices. In order to induce anoxic cell injury, slices were exposed to a 100% $N_2$ atmosphere and control slices were exposed to 100% $O^2$. Irreversible cell injury was estimated by measuring lactate dehydrogenase (LDH) release and alterations in renal cell function were examined by measuring p-aminohippurate (PAH) uptake. Anoxia caused the increase in LDH release in a time-dependent manner. Glycine and glutathione almost completely prevented anoxia-induced LDH release. Of amino acids tested, glycine and alanine exerted the protective effect against anoxia-induced cell injury. However, asparagine with amide side chain, leucine and valine with hydrocarbon side chain, and basic amino acids (lysine, histidine, and arginine) were not effective. Anoxia-induced inhibition of PAM uptake was prevented by glycine. ATP content was decreased by anoxia, which was not affected by glycine. Anoxia-induced depletion of glutathione was significantly prevented by glycine. These results suggest that neutral amino acids with simple structure exert the Protective effect against anoxia-induced cell injury the involvement of specific interaction of amino acids and cell structure.

• Fire Science and Engineering
• /
• v.17 no.3
• /
• pp.26-30
• /
• 2003

This paper presents a study on the analysis for false alarm of heat detector using HRR(Heat Release Rate). And it is represented to threshold value and domain of false alarm. The HRR threshold value of false alarm is calculated to use parameters obtained by small scale fire-experiment. The experiment is conducted to measure detector activation time and flame spread of wood cribs fire, etc. The results show that HRR threshold value of Fixed type detector is 20.24 kW and rate of rise type detector is 13.59 kW, respectively.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 2002.11a
• /
• pp.448-451
• /
• 2002

The possibility of using polypyrrole as a drug delivery system(DDS) has been studied using indicate (Phenol red) and substance with therapeutic activity(Sodium salicylate). In aqueous solution, negative potential is applied to polypyrrole then anion(with therapeutic activity) of sodium salicylate is released by redox processes of polypyrrole. The release amount of anionic drugs from polypyrrole is measured by UV-visible spectrometer which can measure UV-absorbance of materials. Electrode area that use for release amount measurement is$50mm^{2}(5{\times}10mm)$,and thickness of polypyrrole membrane is $15{\mu}m$. DC 1V applied in saline solution, the release amount according to time increased gradually. In various electrode area, release amount of anionic drug is directly to electrode area.

• Archives of Pharmacal Research
• /
• v.19 no.1
• /
• pp.1-5
• /
• 1996

Laminated films composed of drug-containing reservoir layer and drug-free membrane were prepared. Zero-order drug release with lag time was achieved by laminating drug-free film onto the reservoir layer, while burst effect was observed on cast-on film. The rate controlling membrane was either attached to or cast directly into the reservoir. The release rate was independent on the reservoir composition but dependent on the composition of rate-controlling membrane. In growth inhibitory test of cephalexin from Eudragit RS film to Streptococcus Mutans, the disk even after release test for 72 hours showed more bacterial growth inhibition than that of control. Permeation of drug through rat skin was proportional to the HPC fraction in the film. We could control the release of cephalexin from the film by changing the fraction of Eudragit RS, HPC and DEP content. Consequently, Eudragit RS/HPC film was found to be very effective system for local delivery of drugs.

• Journal of Pharmaceutical Investigation
• /
• v.18 no.4
• /
• pp.187-195
• /
• 1988

Poorly permeable $Eudragit^{\circledR}$ RS 100 polymer was used as a wall material for the microencapsulation of zipeprol dihydrochloride by a phase separation method from chloroform-cyclohexane system with 5% polyisobutylene in cyclohexane, and microcapsules obtained were evaluated in vitro by particle size analysis, scanning electron microscopy, drug release test and in vivo bioavailability test in rats. The mechanism of drug release from microcapsules appeared to fit Higuchi matrix model kinetics. The area under the first moment of plasma concentration-time curve of the microcapsules obtained was considerably increased (p<0.05) as compared with that from zipeprol dihydrochloride oral solution. Therefore, it may be suggested that $Eudragit^{\cirledR}$ RS 100 coated zipeprol dihydrochloride microcapsules can be used as a sustained release medication.

• Korean Journal of Applied Biomechanics
• /
• v.13 no.2
• /
• pp.29-47
• /
• 2003

This study is to analyze the kinematic variables in release motion of discuss throwing. For the matter, 5 people from the national team and collegiate discuss throwing in the year 2001 were chosen as the subjects and two S-VHS video cameras set in 60frames/sec were used for recording their motions. Coordinated raw positions data through digitizing are smoothing by butter-worth 's low-pass filtering method at a cut off frequency 6.0Hz. and the direct linear transformation(DLT) method was employed to obtain 3-D position coordinates. The conclusions were as follows; 1. The better record players showed the shorter approach time in the last support phase. 2. In the displacement CG, the better record players showed the shorter displacement in medial-lateral direction, and the longer displacement in horizontal direction. In the motion, the COG showed longer displacement vertical direction. 3. The better record players showed the faster horizontal velocity than vertical velocity in the release. 4. The better record players showed to take the posture of vertical axis in the release.

• Fire Science and Engineering
• /
• v.12 no.3
• /
• pp.31-37
• /
• 1998

The heat release rate of liquid fuels is estimated by oxygen consumption technique. This method is based on the generalization that the heat release rate of combustion per unit of oxygen consumed are approximately the same for most fuels commonly encountered in fires. The oxygen concentration is measured by analyzer of paramagnetic type. The concentrations of CO2 and CO gas are measured by analyzed of Infra-Rad type. Time delays of analyzers are ignored. Results acqired from measuring techniques of exhaust gas concentrations are compared with each other.

• International Journal of Reliability and Applications
• /
• v.2 no.3
• /
• pp.147-160
• /
• 2001

The reliability of computer software is of prime importance for all developers of software. The complicated nature of detecting and removing faults from software has led to a plethora of models for reliability growth. One of the most basic of these is the Jelinski Moranda model, where it is assumed that there are N faults in the software, and that in testing, bugs (or faults) are encountered (and removed when defected) according to a stochastic process at a rate which at a given point in time is proportional to the number of bugs remaining in the system. In this research, we consider the possibility that imperfect repair may occur in any attempt to remove a detected bug in the Jelinski Moranda model. We let p represent the probability that a fault which is discovered or detected is actually perfectly repaired. The possibility that the probability p may differ before and after release of the software is also considered. The distribution of both the number of bugs detected and perfectly repaired in a given time period is studied. Cost models for the development and release of software are investigated, and the impact of the parameter p on the optimal release time minimizing expected costs is assessed.

• Water for future
• /
• v.25 no.3
• /
• pp.115-124
• /
• 1992

The peak flood discharge at a downstream station and the flood travel time between a pair of dams due to a specific flood release from the upper reservoir are computed using a hydraulic river channel routing method. The study covered the whole reservoir system in the Han River. The computed peak flood discharges and the travel times between dams were correlated with the duration and the magnitude of flood release rate at the upstream reservoir, and hence a multiple regression model is proposed for each river reach between a pair of dams. The peak flood discharge at a downstream location can be converted to the peak flood stage by rating curve. Hence, the proposed regression model could be used to forecast the peak flood stage at a downstream location and the flood travel time between dams using the information on the flood release rate and duration from the upper dam.