• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2005.04a
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• pp.204-204
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• 2005

• Science of Emotion and Sensibility
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• v.1 no.1
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• pp.59-67
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• 1998

뇌전위에서 개인차가 없는 일반적인 규칙ㅇ르 지닌 두개의 정보 변수, 즉 ILF와 IHF를 발견하였다. 이러한 일반성을 지닌 정보 변수가 청각, 후각, 촉각 자극에 의해 유발된 쾌하거나 불쾌한 감성 상태를 구분할 수 있으며 전두엽에서 그 경향이 두드러짐을 확인하였다. 전두엽의 뇌전위에서 감성 자극이 주어지가 전과 자극이 주어지는 동안의 ILF, IHF값을 정규화함으로써 새로운 변수, Relative Quantified Emotional State(RQES)를 구현하였다. RQES는 쾌, 중립, 불쾌한 감성의 정도를 선형적으로 정량화하였다. 따라서 하나의 전극으로 측정한 전두엽부분의 뇌전위로부터 RQES값을 계산하면 인간의 쾌, 불쾌 감성을 신뢰도있게 정량화 할 수 있다.

• Journal of the Korean Magnetic Resonance Society
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• v.3 no.2
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• pp.140-148
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• 1999

Using 1H magnetic resonance spectroscopy (MRS), we quantitatively evaluated correlation representing linear relationship between the metabolite peak area ratios associated with poor shimming conditions. The inadequate shimming due to linear shim offsets directly affected overall MR spectral quality as well as peak area for each metabolite. Three major peaks such as N-acetylaspartate (NAA), creatine (Cr,) choline (Cho) were used as a reference for data analysis. Despite considerable variations of metabolite peak area, a significant correlation between the metabolite peak area ratios relative to Cr was established while the correlation between the peak area ratios relative to Cho and NAA was not. The present study suggested that metabolite peak area ratios based on the metabolite of Cr could be an acceptable quantification method even under the poor shimming in clinical MRS examination.

• Journal of Ginseng Research
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• v.43 no.3
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• pp.368-376
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• 2019

Background: In the current phytochemical research on ginseng, the differentiation and structural identification of ginsenosides isomers remain challenging. In this paper, a two-dimensional mass spectrometry (2D-MS) method was developed and combined with statistical analysis for the direct differentiation, identification, and relative quantification of protopanaxadiol (PPD)-type ginsenoside isomers. Methods: Collision-induced dissociation was performed at successive collision energy values to produce distinct profiles of the intensity fraction (IF) and ratio of intensity (RI) of the fragment ions. To amplify the differences in tandem mass spectra between isomers, IF and RI were plotted against collision energy. The resulting data distributions were then used to obtain the parameters of the fitted curves, which were used to evaluate the statistical significance of the differences between these distributions via the unpaired t test. Results: A triplet and two pairs of PPD-type ginsenoside isomers were differentiated and identified by their distinct IF and RI distributions. In addition, the fragmentation preference of PPD-type ginsenosides was determined on the basis of the activation energy. The developed 2D-MS method was also extended to quantitatively determine the molar composition of ginsenoside isomers in mixtures of biotransformation products. Conclusion: In comparison with conventional mass spectrometry methods, 2D-MS provides more direct insights into the subtle structural differences between isomers and can be used as an alternative approach for the differentiation of isomeric ginsenosides and natural products.

• Journal of Animal Science and Technology
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• v.65 no.2
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• pp.401-411
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• 2023

Many studies have been conducted to improve technology for semen cryopreservation in pigs. However, computer-assisted analysis of sperm motility and morphology is insufficient to predict the molecular function of frozen-thawed semen. More accurate expression patterns of boar sperm proteins may be derived using the isobaric tags for relative and absolute quantification (iTRAQ) technique. In this study, the iTRAQ-labeling system was coupled with liquid chromatography tandem-mass spectrometry (LC-MS/MS) analysis to identify differentially expressed CM10-fractionated proteins between fresh and frozen-thawed boar semen. A total of 76 protein types were identified to be differentially expressed, among which 9 and 67 proteins showed higher and lower expression in frozen-thawed than in fresh sperm samples, respectively. The classified functions of these proteins included oxidative phosphorylation, mitochondrial inner membrane and matrix, and pyruvate metabolic processes, which are involved in adenosine triphosphate (ATP) synthesis; and sperm flagellum and motile cilium, which are involved in sperm tail structure. These results suggest a possible network of biomarkers associated with survival after the cryopreservation of Duroc boar semen.

• Nuclear Engineering and Technology
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• v.33 no.3
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• pp.270-282
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• 2001

A simple measure of uncertainty importance based on normalized metric distance to quantify the entire change of cumulative distribution functions (CDFs) has been developed for use in probability safety assessments (PSAs). The metric distance measure developed in this study reflects the relative impact of distributional changes of inputs on the change of an output distribution, white most of the existing uncertainty importance measures reflect the magnitude of relative contribution of input uncertainties to the output uncertainty. Normalization is made to make the metric distance measure a dimensionless quantity. The present measure has been evaluated analytically for various analytical distributions to examine its characteristics. To illustrate the applicability and strength of the present measure, two examples are provided. The first example is an application of the present measure to a typical problem of a system fault tree analysis and the second one is for a hypothetical non-linear model. Comparisons of the present result with those obtained by existing uncertainty importance measures show that the metric distance measure is a useful tool to express the measure of uncertainty importance in terms of the relative impact of distributional changes of inputs on the change of an output distribution.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.140-140
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• 2022

Recently an accurate quantification of streamflow under various climatological and anthropogenic factors and separation of their relative contribution remains challenging, because variation in streamflow may result in hydrological disasters. In this study, we evaluated the factors responsible for variation in streamflow in Korean watersheds, quantified separately their contribution using different Budyko-based functions, and identified hydrological breakpoint points. After detecting that the hydrological break point in 1995 and time series were divided into natural period (1966-1995), and disturbed period (1996-2014). During the natural period variation in climate tended to increase change in streamflow. However, in the disturbed period both climate variation and anthropogenic activities tended to increase streamflow variation in the watershed. Subsequently, the findings acquired from different Budyko-based functions were observed sensitive to selection of function. The variation in streamflow was observed in the response of change in climatic parameters ranging 46 to 75% (average 60%). The effects of anthropogenic activities were observed less compared to climate variation accounts 25 to 54% (average 40%). Furthermore, the relative contribution was observed to be sensitive corresponding to Budyko-based functions utilized. Moreover, relative impacts of both factors have capability to enhance uncertainty in the management of water resources. Thus, this knowledge would be essential for the implementation of water management spatial and temporal scale to reduce the risk of hydrological disasters in the watershed.

• Journal of the Korean Society of Radiology
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• v.17 no.7
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• pp.1017-1023
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• 2023

The purpose of this study was to improve the accuracy of effective atomic number (EAN) and relative electron density (RED) using a polynomial-based calibration method using dual-energy CT images. A phantom composed of 11 tissue-equivalent materials was acquired with dual-energy CT to obtain low- and high-energy images. Using the acquired dual-energy images, the ratio of attenuation of low- and high-energy images for EAN was calibrated based on Stoichiometric, Quadratic, Cubic, Quartic polynomials. EAN and RED were extracted using each calibration method. As a result of the experiment, the average error of EAN using Cubic polynomial-based calibration was minimum. Even in the RED image extracted using EAN, the error of the Cubic polynomial-based RED was minimum. Cubic polynomial-based calibration contributes to improving the accuracy of EAN and RED, and would like to contribute to accurate diagnosis of lesions in CT examinations or quantification of various materials in the human body.

• Journal of the Ergonomics Society of Korea
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• v.25 no.2
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• pp.187-196
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• 2006

This study aims to develop luxuriousness models based on both users' subjective feelings and objective material characteristics of automobile crash pad using Kansei engineering approach. Based on the results of literature survey and FGI, 12 Kansei variables describing look-and-feel and touch feel and crash pad design variables were extracted for systematically developing both a conceptual model of luxuriousness and a questionnaire for Kansei evaluation. A total of 41 various crash pad samples and 60 participants(customers: 30, designers: 30) were employed to evaluate the crash pad samples using the questionnaire with 9-point semantic differential scale and 100-point modified magnitude estimate scale. Based on the survey results, luxuriousness models were developed by using regression and quantification I method. In addition, they were compared and contrasted with respect to the relative importance of Kansei variables. Consequently, the developed luxurious model could suggest the preferred combination of material properties of crash pad.

• Journal of Environmental Impact Assessment
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• v.2 no.2
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• pp.59-71
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• 1993

Evaluation methods are employed in environmental impact assessment to choose between different project site, to determine the required measures to compensate impact and to decide whether the environmental impacts are more important than the social or economic effects of a project. The main obstacles that restrict use of quantitative evaluation method are a Lack of knowledge about the environmental effects (e.g. if impacts on wildlife or landscape amenities are predicted) and the relative importance of economic and social issues compared with nature conservation stability of ecosystem or landscape beauty. In Germany, the most common method for site planning is the "ecological risk analysis". It is a kind of multi-criteria-decision-method based on quantitative and qualitative description and ordinal ranking. The various kinds of "ecological balancing methods" that are more recently developed (within the last decade) to quantify the required amount for compensatory measures instead often use cardinal figures to express the value of ecosystems, the intensity of impacts, the need for additional measures to compensate for long recuperative periods when restoring ecosystems and so on. There are still only a view attempts to quantify decisions between environmental and socio-economic issues. Multicriteria-analysis as well as cost-benifit-analysis was used. Some new approaches which are still in a preliminary status are based on contingent valuation and on calculations for compensatory payments (instead of compensatory measures).