• 응용통계연구
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• 제22권2호
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• pp.387-402
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• 2009

In this paper we have considered the problem of estimating the population mean $\bar{Y}$ of the study variable y using auxiliary information in presence of non-response. Classes of estimators for $\bar{Y}$ in the presence of non-response on the study variable y only and complete response on the auxiliary variable x is available, have been proposed in different situations viz., (i) population mean $\bar{X}$ is known, (ii) when population mean $\bar{X}$ and variance $S^2_x$ are known; (iii) when population mean $\bar{X}$ is not known: and (iv) when both population mean $\bar{X}$ and variance $S^2_x$ are not known: single and two-phase (or double) sampling. It has been shown that various estimators including usual unbiased estimator and the estimators reported by Rao (1986), Khare and Srivastava (1993, 1995) and Tabasum and Khan (2006) are members of the proposed classes of estimators. The optimum values of the first phase sample size n', second phase sample size n and the sub sampling fraction 1/k have been obtained for the fixed cost and the fixed precision. To illustrate foregoing, we have carried out an empirical investigation to reflect the relative performance of all the potentially competing estimators including the one due to Hansen and Hurwitz (1946) estimator, Rao (1986) estimator, Khare and Srivastava (1993, 1995) and Tabasum and Khan (2006) estimator.

• Bulletin of the Korean Chemical Society
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• 제32권5호
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• pp.1547-1553
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• 2011

An effective analytical method of gas chromatography/mass spectrometry (GC/MS) was developed for the rapid determination of essential oils in the crude extract of Acorus species (Acorus gramineus, Acorus tatarinowii, and Acorus calamus). Major phenypropanoids (${\beta}$,${\alpha}$-asarone isomers, euasarone, and methyleugenol) and ${\beta}$-caryophyllene in Acorus species were used as marker compounds and determined for the quality control of herbal medicines. To extract marker compounds, various extraction techniques such as solvent immersion, mechanical shaking, and sonication were compared, and the greatest efficiency was observed with sonication extraction using petroleum ether. The dynamic range of the GC/MS method depended on the specific analyte; acceptable quantification was obtained between 10 and 2000 ${\mu}g/mL$ for ${\beta}$-asarone, 10 and 500 ${\mu}g/mL$ for ${\alpha}$-asarone, 10 and 200 ${\mu}g/mL$ for methyleugenol, and between 5 and 100 ${\mu}g/mL$ for ${\beta}$-caryophyllene. The method was deemed satisfactory by inter- and intra-day validation and exhibited both high accuracy and precision, with a relative standard deviation < 10%. Overall limits of detection were approximately 0.34-0.83 ${\mu}g/mL$, with a standard deviation (${\sigma}$)-to-calibration slope (s) ratio (${\sigma}$/s) of 3. The limit of quantitation in our experiments was approximately 1.13-3.20 ${\mu}g/mL$ at a ${\sigma}$/s of 10. On the basement of method validation, 20 samples of Acorus species collected from markets in Korea were monitored for the quality control. In addition, principal component analysis (PCA) and hierarchical cluster analysis (HCA) were performed on the analytical data of 20 different Acorus species samples in order to classify samples that were collected from different regions.

• 분석과학
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• 제33권3호
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• pp.125-133
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• 2020

Methylisothiazolinone (MIT) and chloromethylisothiazolinone (CMIT) cause allergic contact dermatitis and are banned cosmetics ingredients, except in rinse-off products. However, their presence has been detected in cosmetics. We report a UPLC-tandem MS/MS screening method for their simultaneous determination in cosmetics. To facilitate extraction from various matrices, pretreatment methods were developed for each sample type. The method was optimized through a series of assessments, including specificity, LOD, LOQ, linearity, recovery, stability, precision, and accuracy. The LODs and LOQs for MIT ranged from 0.054 and 0.163 ㎍ mL^-1 whereas those for CMIT ranged from 0.040 and 0.119 ㎍ mL^-1. The linear correlation coefficients (r²) were higher than 0.999. Relative standard deviations (RSDs) for both intra- and inter-day measurements ranged from 0.3 ~ 13.6 %. Recoveries at three different concentrations were within 87.9 ~ 118.9 %. The RSD for stability measurements of spiked samples was within 7 %. These results confirm the suitability of the developed method for the simultaneous quantitation of MIT and CMIT in cosmetics. Samples of 320 color cosmetics, including eyeshadows, solid lipsticks, liquid lipsticks, and nail polishes were analyzed using the developed method, and two of them were found to contain both MIT and CMIT and one of them was found to contain only MIT. This data and the method will aid the regulation of ingredients used in cosmetics.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권10호
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• pp.4968-4986
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• 2017

In this paper, we primarily address the difficulty of automatic generation of a plausible depth map from a single image in an unstructured environment. The aim is to extrapolate a depth map with a more correct, rich, and distinct depth order, which is both quantitatively accurate as well as visually pleasing. Our technique, which is fundamentally based on a preexisting DepthTransfer algorithm, transfers depth information at the level of superpixels. This occurs within a framework that replaces a pixel basis with one of instance-based learning. A vital superpixels feature enhancing matching precision is posterior incorporation of predictive semantic labels into the depth extraction procedure. Finally, a modified Cross Bilateral Filter is leveraged to augment the final depth field. For training and evaluation, experiments were conducted using the Make3D Range Image Dataset and vividly demonstrate that this depth estimation method outperforms state-of-the-art methods for the correlation coefficient metric, mean log10 error and root mean squared error, and achieves comparable performance for the average relative error metric in both efficacy and computational efficiency. This approach can be utilized to automatically convert 2D images into stereo for 3D visualization, producing anaglyph images that are visually superior in realism and simultaneously more immersive.

• 한국환경보건학회지
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• 제41권5호
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• pp.358-367
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• 2015

Objectives: This study was performed to evaluate the analytical method for PAH metabolites in human urine using enzyme hydrolysis and solid-phase extraction coupled with LC-(ESI)-MS/MS technique. Methods: We employed HPLC tandem mass spectrometry techniques with appropriate pre-treatment for analysis of 16 OH-PAHs in human urine. Samples were hydrolysis by ${\beta}$-flucuronidase/Aryl sulfatase, and target compounds were extracted by solid-phase extraction with a strata-x cartridge. Cross-validation was performed between Eulji University and Green Cross laboratories with 200 human urine samples. Results: The accuracies were between 90.3% and 118.8%, and precisions (relative standard deviations) were lower than 10%. The linearity obtained was satisfying for the 16 OH-PAH compounds, with a coefficient of determination ($r^2$) higher than 0.99. The results of cross-validation at the two organizations were compared by ICC (interclass correlation coefficient) values. The cross-validation results were excellent or good for all compounds. Conclusion: An analytical method was validated for low nanogram levels of 16 OH-PAHs in human urine. Also, satisfying results were obtained for method validation such as accuracy, precision and ICC of cross-validation.

• 대한기계학회논문집B
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• 제28권3호
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• pp.265-270
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• 2004

Experiment study on a down scaled two-phase catalytic reactor is presented. As a preliminary step for the development of catalytic reactor, nano-particulate catalyst was prepared. Perovskite La$\_$0.8/Sr$\_$0.2/CoO$_3$is chosen and synthesized as a catalyst considering superior catalytic performance in reduction and oxidation process where oxygen is involved among the reagent. Reactor that has a scale of 2${\times}$10${\times}$25mm was made by machining of A1 block as a layered structure considering further extension to micro-machining. Hydrogen peroxide of 70wt% was adopted as reactant and was provided to the reactor loaded with 1.5 g of catalyst. Reactant flow rate was varied by precision pump with a range of 0.15cc/min to 17.2cc/min. Temperature distribution within reactor was recorded by 3 thermocouples and total amount of liquid product was measured. Temperature distribution and factors that affect temperature were observed and relation between temperature distribution and production rate was also analyzed. Relative time scale plays a significant role in the performance of the reactor. To obtain steady state operation, appropriate ratio of flow rate, catalyst mass and reactor geometry is required and furthermore to get more efficient production rate temperature distribution should be evenly distributed. The database obtained by the experiment will be used as a design parameter for micro reactor.

• 대한기계학회논문집A
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• 제37권4호
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• pp.447-459
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• 2013

실제 산업현장에서 비젼 시스템을 적용하기에는 로봇 비젼 제어알고리즘의 기구학모델의 정확도, 로봇이 움직이는 동안 카메라 초점거리와 방위에 대한 보정, 3 차원 물리적 좌표에서 2 차원 카메라 좌표로의 매핑에 대한 이해 등 해결해야 할 많은 문제점들이 있다. 본 논문에 제안된 비젼 시스템 모델은 카메라와 로봇 사이의 상대적인 위치가 알려지지 않아도 제어가 가능하고, 카메라 보정 문제를 해결하기 위해 6 개의 카메라 매개변수를 가지는 비젼 시스템 모델을 제시하였으며, 이를 이용하여 로봇 비젼 제어알고리즘 개발에 N-R 방법과 EKF 방법을 적용하였다. 최종적으로 N-R 과 EKF 방법에 의하여 개발된 로봇 비젼 제어 알고리즘의 위치 정밀도와 데이터 처리 시간을 얇은 막대 배치작업을 수행하여 비교하였다.

• 분석과학
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• 제9권1호
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• pp.20-25
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• 1996

암석 및 토양 등의 지질시료에 미량으로 존재하는 우라늄과 토륨을 파장분산형 X-선 형광분석법을 사용하여 정량하였다. X-선관의 target 물질로 사용되는 Rh의 산란선을 내부 표준물질로 사용하였다. 토륨의 경우는 50초, 그리고 우라늄의 경우는 400초 동안 측정하였을 때, 우라늄과 토륨의 X-선 형광분석결과는 중성자방사화분석 및 유도결합플라즈마 원자방출분광분석의 결과와 큰 차이를 보이지 않았으며 10% 이내의 정밀도와 15% 이내의 정확도를 보여 주었다.

• 한국측량학회지
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• 제33권2호
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• pp.123-129
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• 2015

알고리즘의 유연성 및 효율성으로 인해 GPS 이동측위 시 칼만필터가 주로 사용되어 왔으며 동시에 다양한 계통오차의 제거가 가능한 상대측위 기법이 널리 사용되어 왔다. 하지만 기선의 길이가 길어지게 되면 상대측위 기법을 사용하더라도 대기효과를 충분히 제거하기 어렵기 때문에 이 경우 제거되지 않고 남아 있는 대기효과를 상태벡터에 추가하여 추정을 하기도 한다. 칼만필터를 이용하는 경우 일반적으로 대기효과는 랜덤워크 혹은 일차가우스-마르코프 프로세스로 모델링하게 되는데 이때 프로세스 잡음에 대한 정확한 모델링이 필수적이다. 본 연구에서는 대기효과에 해당되는 프로세스 잡음 모델링을 위해 필요한 매개변수를 결정하였다. 이를 위해 이중차분 전리층 지연값과 천정방향 습윤지연값을 이용하여 실험적 자기상관함수를 계산하였으며 이를 통해 프로세스 잡음 모델링에 필요한 매개변수를 계산하였다. 결정된 매개변수값들은 유사한 대기환경에서 취득된 데이터에 대한 프로세스 잡음 모델링 시 직접 사용될 수 있으며 유사한 대기환경이 아닌 경우일 지라도 초기 근사값으로 활용될 수 있을 것이다.

• 대한본초학회지
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• 제25권3호
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• pp.65-71
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• 2010

Objectives：To develop and validate HPLC-PDA methods for simultaneous determination of seven constituents in Samchulkunbi-tang (SKT). Additionally, we investigated the cytotoxicity against BEAS-2B cell line and splenocytes of SKT. Methods：Reverse-phase chromatography using a Gemini $C_{18}$ column operating at $40^{\circ}C$, and photodiode array (PDA) detection at 230, 254 and 280 nm, were used for quantification of the three marker components of SKT. The mobile phase using a gradient flow consisted of two solvent systems. Solvent A was 1.0% (v/v) aqueous acetic acid and solvent B was acetonitrile with 1.0% (v/v) acetic acid. The cytotoxicity of SKT were measured by the CCK-8 assay method. Results：Calibration curves were acquired with $r^2$>0.9999, and the relative standard deviation (RSD) values (%) for intra- and inter-day precision were less than 6.0%. The recovery rate of each compound was in the range of 86.89-109.78%, with an RSD less than 4.0%. The contents of seven compounds in SKT were 1.39-6.84 mg/g. SKT had no cytotoxicity effect at 50-200 ${\mu}g$/mL concentrations. Conclusions：The established method will be helpful to improve quality control and in vitro efficacy study of SKT.