• Title/Summary/Keyword: Relative growth ratio

Search Result 381, Processing Time 0.034 seconds

Increased Serum Endoglin and Transforming Growth Factor β1 mRNA Expression and Risk of Hepatocellular Carcinoma in Cirrhotic Egyptian Patients

  • Teama, Salwa;Fawzy, Amal;Teama, Shirin;Helal, Amany;Drwish, Amira Diyaa;Elbaz, Tamer;Desouky, Eman
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.5
    • /
    • pp.2429-2434
    • /
    • 2016
  • Transforming growth factor-B1 ($TGF-{\beta}1$ )and its coreceptor endoglin (ENG) have been shown to contribute to hepatocellular tumor development and malignant progression. Our aim was to evaluate the serum expression levels of $ENG/TGF-{\beta}1$ mRNAs and risk of hepatocellular carcinoma in cirrhotic Egyptian patients. Our study included 77 subjects. Real time polymerase chain reaction was used to evaluate the expression level of ENG and $TGF-{\beta}1$mRNAs. The relative expression ratio of ENG mRNA was 0.82 (0.1 -3.2), 0.66 (0.15-5.3), 0.38(0.007-2.8) and 0.12 (0.00-0.22) and the relative expression ratio of $TGF-{\beta}1$mRNA was 1.4 (0.19 -6.2), 1.2 (0.22-4.3), 1.0 (0.15-4.4) and 0.6 (0.00-2.2) for cirrhotic HCC cirrhotic, HCC only and healthy control groups respectively. Increased ENG and $TGF-{\beta}1$ mRNA gene expression was correlated with TNM clinical stage. The expression ratio in TNM stage III-IV 1.1 (0.07-3.2), 1.55 (0.15-6.2) was statistically significantly higher than that in stage I-II 0.47 (0.007-2.8), 1.0 (0.31-4.4) (P<0.05). Our data suggested that increased ENG and $TGF-{\beta}1$ gene expression may participate in hepatocarcinogenesis and increased risk of HCC in individuals with cirrhosis. Early screening for evidence of cirrhosis and consideration of ENG and $TGF-{\beta}1$ as targets for therapy and treatment strategies are warranted.

BIOLOGICAL STUDIES ON OYSTER CULTURE(III) Oyster Growth Comparison between 4 Farms in Hansan - Geoje Bay and Density-dependent Relative Shell Growth (굴의 양식에 관한 생물학적 연구(III) 한산${\cdot}$거제만내 양식장별 굴의 성장비교와 부착밀도에 따른 패각의 상대성장)

  • YOO Sung Kyoo;PARK Kyung Yang
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.13 no.4
    • /
    • pp.207-212
    • /
    • 1980
  • Growth rates of oysters at four oyster farms in Hansan-Geoje Bay, near Chungmu, southern Korea, and density-dependent relative shell growth were investigated from November 1979 to May 1980 with the following results: The oysters at Sorang farm showed the best growth, the shell height in May 1980 attaining 10.10 cm, at Hwado 8.69cm and Songdo 8.57cm, all of which started growing in June 1979. At Chubong the oysters which started growing in July attained 8.6cm. The best grown oysters at Sorang shelved relatively slow growth in meat weight until February 1980, and then showed rapid growth upto May. At Hwado and Songdo they grew fast from December 1979 to February 1950, and from April to May 1980. Those at Chubong gradually increased growth rate from December 1979, and in April and May they showed rapid growth but still being smaller than the others. The ratio of meat weight to shell weight increased at Whado, Songdo and Chuhong after December 1979, but at Sorang it increased rapidly after February 1980. The ratio of shell length to shell height was 0.60 and up when the individual number of oysters attached to each cultch-disc(oyster shell) was less than 13, 0.56 to 0.60 when 14 to 25, and 0.51 or less when over 28, respectively.

  • PDF

Growth and Sex Ratio of Juvenile Olive Flounder (Paralichthys olivaceus) at Different Size-ranks

  • Kim, Jong-Hyun;Kim, Hyun-Chul;Noh, Jae-Koo;Lee, Jeong-Ho;Kang, Jung-Ha;Kim, Kyung-Kil
    • Fisheries and Aquatic Sciences
    • /
    • v.10 no.4
    • /
    • pp.191-195
    • /
    • 2007
  • The aim of this study was to assess whether size-rank at the juvenile stage is associated with growth performance and sex ratio in olive flounder (Paralichthys olivaceus). Juveniles (mean body weight, $8.8{\pm}0.9\;g$) were selected from two age groups, with the high size-rank group (HSRG) fish in the upper 19.3-67.3% of 104 days post-hatching (dph) age group and the low size-rank group (LSRG) fish in the lower 9.0-55.7% of 116 dph age group. Triplicate groups of 100 fish were reared over 32 weeks. A heavier final body weight was observed in the HSRG ($360{\pm}12\;g$) compared to the LSRG ($315{\pm}9\;g$, P<0.05), whereas no differences in feed intake, feeding efficiency, and mortality were seen between the experimental groups. The percentage of females was significantly higher in the HSRG (51.7%) than in the LSRG (30.8%, P<0.05). In addition, a remarkable increase in growth was recorded in females, indicating that the relative frequency of females increased with a body weight increase. The results suggest that high size-rank juvenile olive flounder have better growth performance and a higher percentage of females, because females start growing faster than males before size grading occurs.

Nano-Scale Observation of Fatigue Striations for Aluminum Alloy (알루미늄 합금 피로 스트라이에이션의 나노 스케일 관찰)

  • Choe, Seong-Jong;Gwon, Jae-Do;Ishii, Hitoshi
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.25 no.7
    • /
    • pp.1047-1054
    • /
    • 2001
  • Atomic Force Microscope (AFM) was used to study cross sectional profiles and dimensions of fatigue striations in 2017-T351 aluminum alloy. Their widths(SW) and heights (SH, SH(sub)h, SH(sub)ι) were measured from the cross sectional profiles of three-dimension AFM images. The following results that will be helpful to understand the fatigue crack growth mechanism were obtained. (1) The relation of SH=$\alpha$(SW)(sup)1.2 was obtained. (2) The ratio of the striation height to its width SH/SW, SH(sub)h/SW and SH(sub)ι/SW did not depend on the stress intensity factor range ΔK and the stress ratio R( =P(sub)min/P(sub)max = K(sub)min/K(sub)max). (3) Effect of precipitate on the morphology of striation was changed by the relative dimensional difference between the striation width SW and the precipitates. From these results, the applicability of the AFM to nano-fractography is discussed.

Growth Performance, Meat Yield, Oxidative Stability, and Fatty Acid Composition of Meat from Broilers Fed Diets Supplemented with a Medicinal Plant and Probiotics

  • Hossain, Md. Elias;Kim, Gwi-Man;Lee, Sung-Ki;Yang, Chul-Ju
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.25 no.8
    • /
    • pp.1159-1168
    • /
    • 2012
  • The experiment was carried out to investigate the effects of Alisma canaliculatum with probiotics (ACP) on the growth performance, meat composition, oxidative stability, and fatty acid composition of broiler meat. Sixteen probiotic strains were tested for their levels of acid, bile, and heat tolerance. Among them, Lactobacillus acidophilus KCTC 3111, Enterococcus faecium KCTC 2022, Bacillus subtilis KCTC 3239, and Saccharomyces cerevisiae KCTC 7928 were selected for use in ACP. Exactly 140 Ross broiler chicks were assigned to four dietary treatments in five replications for 5 wks in a completely randomized design. The dietary treatments were NC (Negative control; basal diet), PC (Positive control; basal diet with 0.005% Chlortetracycline), ACP-0.5% (basal diet with 0.5% ACP powder), and ACP-1% (basal diet with 1% ACP powder). According to the results, body weight of the broilers increased, and feed conversion ratio improved in the ACP-0.5% group compared to the NC group (p<0.05). Crude protein content of breast meat was higher (p<0.05) in the ACP-0.5% group, whereas crude fat content of thigh meat was lower (p<0.05) in the supplemented groups. Breast meat absolute and relative weights were both higher (p<0.05) in the ACP groups compared to the control group. Further, ACP diets increased gizzard and decreased large intestine relative weights, whereas kidney relative weight decreased upon the addition of a higher level (1%) of ACP (p<0.05). Thiobarbituric acid reactive substances values of breast and thigh meats were reduced (p<0.05) by ACP supplementation compared to control. Regarding the fatty acid composition of breast meat, arachidonic acid, docosahexaenoic acid, PUFA, and n6 fatty acid levels decreased (p<0.05) in the ACP groups, whereas the levels of linoleic acid, PUFA, PUFA/SFA, and n6 fatty acid in thigh meat decreased (p<0.05) by ACP and PC diets. It can be suggested based on the study results that ACP-0.5% diet could be an effective feed additive for broilers.

Allelopathic Effects of Growth Inhibitor from Artemisia princeps var. orientalis (쑥에 들어 있는 生長 抑制物質의 作用)

  • Kil, Bong-Seop;Young-Sik Kim;Kyeong-Won Yun
    • The Korean Journal of Ecology
    • /
    • v.14 no.2
    • /
    • pp.121-135
    • /
    • 1991
  • A number of laboratory experimentes have performed to elucidate water-soluble of volatile substances from wormwood plant(artemisia princeps var. orientalis) as growth inhibitor or phytotoxicant. in germination tests with aqueous extracts of leaves, stems and roots of the wormwood plants, most tested species showed that relative germination ratio was inversely proportional to comcentration of the extracats. and seedling elongation and dry weight of the species were heavily inhibited with the extracts, incubated leaves, volatile substances of the leaves and soil underneath wormwood plants. gas Chromatography was employed to find out possible phytotoxic substances or growth inhibitors of wormwood leaves. ten substantes have isolated, and most of them were identified as terpenoids.

  • PDF

The Prediction of Remaining Service Life of Land Concrete Due to Steel Corrosion (철근부식에 의한 육지 콘크리트의 잔존수명 예측)

  • 정우용;윤영수;송하원;변근주
    • Journal of the Korea Concrete Institute
    • /
    • v.12 no.5
    • /
    • pp.69-80
    • /
    • 2000
  • This paper presents the prediction of remaining service life of the concrete due to steel corrosion caused by the following three cases; carbonation, using sea sand and using deicing salts. The assessment of initiation period was generalized considering the existing perdiction models in the literature, corrosion experiment and field assessment. To evaluate the prediction equation of rust growth, the corrosion accelerating experiments was performed. The polarization resistance was measured by potentiostat and the conversion coefficient of polarzation resistance to corrosion rate was determined by the measurement of real mass loss. Chloride content, carbonation, cover depth, relative humidity, water-cement ratio(W/C), and the use of deicing salts were taken into account and the resulting prediction equation of rust growth was proposed on the basis of these properties. The proposed equation is to predict the rust growth during any specified period of time and be effective in particular for predicting service life of concrete in the case of using sea sand.

Allelopathy of Tagetes minuta L. Aqueous Extracts on Seed Germination and Root Hair Growth

  • Kil, Ji-Hyun;Shim, Kew-Cheol;Lee, Kyu-Jin
    • The Korean Journal of Ecology
    • /
    • v.25 no.6
    • /
    • pp.395-398
    • /
    • 2002
  • Present paper showed allelopahtic effects of Tagetes minuta aqueous extracts on seed germination and root hair development. Allelopathy of aqueous extracts derived from T. minuta examined using two test plant species (Lotus comiculatus var. japonicus and Lactuca sativa). The seeds of test species were inoculated in petri dishes containing 0, 10,50 and 100% aqueous extracts from T. minuta. At day 5, the relative seed germination ratio to control was evaluated, and the development of seedling root hairs was observed through light microscopy. Seed germination of L. comiculatus var. japonicus was significantly inhibited proportional to the concentrations of aqueous extract, but that of L. sativa wasn't inhibited. The inhibitory allelopathic effect of T. minuta was found in the development and growth of seedling root hairs. It was concluded that the inhibitory allelophatic effects have been to be investigated using various bioassay, for the allelopathy of plant species shows species-specific and organ-specific.

Characteristics of fluoride/glass as a seed layer for microcrystalline silicon film growth

  • Choi, Seok-Won;Kim, Do-Young;Ahn, Byeong-Jae;Yi, Jun-Sin
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 2000.01a
    • /
    • pp.65-66
    • /
    • 2000
  • Various fluoride films on a glass substrate were prepared and characterized to provide a seed layer for crystalline Si film growth. The XRD analysis on $CaF_2/glass$ illustrated (220) preferential orientation and showed lattice mismatch less than 5 % with Si. We achieved a fluoride film with breakdown electric field of 1.27 MV/cm, leakage current density about $10^{-6}$ $A/cm^2$, and relative dielectric constant less than 5.6. This paper demonstrates microcrystalline silicon $({\mu}c-Si)$ film growth by using a $CaF_2/glass$ substrate. The ${\mu}c-Si$ films exhibited crystallization in (111) and (220) planes, grain size of $700\;{\AA}$, crystalline volume fraction over 65 %, dark- and photo-conductivity ratio of 124, activation energy of 0.49 eV, and dark conductivity less than $4{\times}10^{-7}$ S/cm.

  • PDF

Correlation Between Relative Light Intensity and Physiological Characteristics of Forsythia saxatilis in Bukhansan Natural Habitats (북한산 산개나리의 자생지 내 상대 광량과 생리적 특성간 상관 관계)

  • Han, Sim-Hee;Kim, Gil Nam;Kim, Du-Hyun;Kim, Kyung-Hee
    • Journal of Korean Society of Forest Science
    • /
    • v.101 no.2
    • /
    • pp.236-243
    • /
    • 2012
  • The leaf growth and physiological characteristics of Forsythia saxatilis were investigated at six natural habitats under different light intensities in Bukhansan in order to figure out an appropriate growth environment for conservation and restoration of F. saxatilis that is Korean endemic plant designated as rare and endangered species. Relative light intensities (RLI) at six habitats showed from 10% to 78% of the full sun. Leaf length, leaf width, leaf area and dry leaf weight of population under highest relative light intensity (78%) were the highest. The ratio of dry leaf weight to leaf area increased with the increase of RLI. The content of photosynthetic pigments such as chlorophyll a, b and carotenoid were the highest at 78% of RLI, whereas the ratio of total chlorophyll to carotenoid content reduced according to the increase of RLI. Photosynthetic parameters, such as photosynthetic rate, also increased with the increase of RLI. The total nonstructural carbohydrate (TNC) was 1.5 times higher at 78% of RLI than that at 10% of RLI and the total soluble sugar (TSS) was the highest at 78% of RLI. In conclusion, leaf characteristics and physiological characteristics have high positive correlation with light intensity. Therefore, light condition should be primarily considered to improve growth and physiology characteristics of F. saxatilis under low light intensity.