• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.05a
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• pp.826-831
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• 2005

In this paper the effect of moving mass on dynamic behavior of cracked cantilever beam on elastic foundations is presented. Based on the Euler-Bernoulli beam theory, the equation of motion can be constructed by using the Lagrange's equation. The crack section is represented by a local flexibility matrix connecting two undamaged beam segments. That is, the crack is modelled as a rotational spring. This flexibility matrix defines the relationship between the displacements and forces across the crack section and is derived by applying fundamental fracture mechanics theory. The crack is assumed to be in the first mode of fracture. As the depth of the crack is increased, the tip displacement of the cantilever beam is increased. When the crack depth is constant the frequency of a cracked beam is proportional to the spring stiffness.

• Journal of the Korea Safety Management & Science
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• v.2 no.4
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• pp.113-124
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• 2000

First, in order to improve selecting method of quality characteristic level desired by customers, S/N(Signal-to-Noise) ratio of Taguchi in larger-the-better characteristics was applied. Second, the Matrix classification standard of ACE(Attribute Categorization Evaluation) is presented using KANO model on difference analysis of importance and satisfaction through questionnaire from customers. This is for reflecting the diverse EC which customers want in EC quality sufficiently. Also, establishing sales point will be helpful in business strategy through presenting types that are able to decide planning quality. Third, the important measure of EC about correlation among quality characteristics and a new weight of EC are calculated depending on importance of EC and the weight of customer attribute and materials of relationship matrix through correlation matrix analysis.

• Journal of Ocean Engineering and Technology
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• v.17 no.6
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• pp.47-52
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• 2003

To determine the effect of transverse open crack on the dynamic behavior of simply-supported Euler-Bernoulli beam with the moving masses, an iterative modal analysis approach is developed. The influence of depth and position of the crack in the beam, on the dynamic behavior of the simply supported beam system, have been studied by numerical method. The cracked section is represented by a local flexibility matrix, connecting two undamaged beam segments that is, the crack is modeled as a rotational spring. This flexibility matrix defines the relationship between the displacements and forces across the crack section, and is derived by applying a fundamental fracture mechanics theory. As the depth of the crack is increased, the mid-span deflection of the simply-supported beam, with the moving mass, is increased. The crack is positioned in the middle point of the pipe, and the mid-span defection of the simply-supported pipe represents maximum deflection.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.1
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• pp.143-151
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• 2005

This paper study the effect of open cracks on the dynamic behavior of simply supported Timoshenko beam with a moving mass. The influences of the depth and the position of the crack in the beam have been studied on the dynamic behavior of the simply supported beam system by numerical method. Using Lagrange's equation derives the equation of motion. The crack section is represented by a local flexibility matrix connecting two undamaged beam segments i.e. the crack is modeled as a rotational spring. This flexibility matrix defines the relationship between the displacements and forces on the crack section and is derived by the applying fundamental fracture mechanics theory. As the depth of the crack is increased the mid-span deflection of the Timoshenko beam with the moving mass is increased. And the effects of depth and position of crack on dynamic behavior of simply supported beam with moving mass are discussed.

• Journal of Pharmaceutical Investigation
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• v.37 no.3
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• pp.173-177
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• 2007

The purpose of this study was to investigate the effect of salt formation on the percutaneous absorption of meloxicam through hairless mouse skin from a pressure sensitive adhesive (PSA) matrix. In addition, the influences of enhancers on the permeation of meloxicam or meloxicam-ethanolamine (MX-EA) salts across the hairless mouse skin were evaluated using a flow-through diffusion cell system. The salt formation of meloxicam resulted in lower permeation rate than the parent drug. $Span^{(R)}$ 80 provided the highest enhancing effect for meloxicam and meloxicam monoethanolamine salt. The maximum amount of the drug that can be loaded without retarding permeation rate was different depending on the compound. No relationship was found between the fluxes of meloxicam or MX-EA salts from saturated solutions and those from PSA matrices containing the same enhancer.

• Proceedings of the Safety Management and Science Conference
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• 2000.05a
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• pp.481-490
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• 2000

First, in order to improve selecting method of quality characteristic level desired by customers, S/H(Signal-to-Noise) ratio of Taguchi in larger-the-better characteristics was applied. Second, the Matrix classification standard of ACE(Attribute Categorization Evaluation) is presented using KANO model on difference analysis of importance and satisfaction through questionnaire from customers. This is for reflecting the diverse EC which customers want in EC quality sufficiently. Also, establishing sales point will be helpful in business strategy through presenting types that are able to decide planning quality. Third, the important measure of EC about correlation among quality characteristics and a new weight o( EC are calculated depending on importance of EC and the weight of customer attribute and materials of relationship matrix through correlation matrix analysis.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.15 no.10 s.103
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• pp.1195-1201
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• 2005

In this paper, the effect of a moving mass on dynamic behavior of the cracked cantilever beam on elastic foundations is presented. Based on the Euler-Bernoulli beam theory, the equation of motion can be constructed by using the Lagrange's equation. The crack section is represented by a local flexibility matrix connecting two undamaged beam segments. That is, the crack is modelled as a rotational spring. This flexibility matrix defines the relationship between the displacements and forces across the crack section and is derived by applying fundamental fracture mechanics theory The crack is assumed to be in the first mode of fracture. As the depth of crack is increased, the tip displacement of the cantilever beam is Increased. When the depth of crack is constant, the frequency of a cracked beam is proportional to the spring stiffness.

• Structural Engineering and Mechanics
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• v.57 no.3
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• pp.389-402
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• 2016

Based on the traditional mechanical model of thin-walled straight beam, the paper makes analysis and research on the pre-twisted thin-walled beam finite element numerical model. Firstly, based on the geometric deformation differential relationship, the Saint-Venant warping strain of pre-twisted thin-walled beam is deduced. According to the traditional thin-walled straight beam finite element mechanical model, the finite element stiffness matrix considering the Saint-Venant warping deformations is established. At the same time, the paper establishes the element stiffness matrix of the pre-twisted thin-walled beam based on the classic Vlasov Theory. Finally, by calculating the pre-twisted beam with elliptical section and I cross section and contrasting three-dimensional solid finite element using ANSYS, the comparison analysis results show that pre-twisted thin-walled beam element stiffness matrix has good accuracy.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6639-6643
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• 2015

Background: Prostate cancer is a major concern of public health. Microvascular density (MVD) is one of the prognostic markers for various solid cancers. Matrix metalloproteinase 11 (MMP11) plays an important role in angiogenesis and changes in its expression level are known to be associated with tumor progression and clinical outcome. Aim: To investigate the relationship between MVD and MMP11 expression in prostatic adenocarcinoma tissues. Materials and Methods: The expression levels of MMP11 and MVD were analyzed immunohistochemically for 50 specimens of prostatic adenocarcinoma. Results: MMP11 was mainly expressed in stromal cells but rarely seen in epithelial cells. Mean MVD was $36/mm^2$, and it was correlated significantly only with bone metastases. MVD was also significantly correlated with MMP11 expression (r=0.29, p=0.044). Conclusions: MMP11 may alter the stromal microenvironment of prostate cancer to stimulate tumor angiogenesis.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.15 no.4 s.97
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• pp.483-491
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• 2005

In this paper a dynamic behavior of a double-cracked cantilever pipe with the tip mass and a moving mass is presented. Based on the Euler-Bernoulli beam theory, the equation of motion is derived by using Lagrange's equation. The influences of the moving mass, the tip mass and double cracks have been studied on the dynamic behavior of a cantilever pipe system by numerical method. The cracks section are represented by the local flexibility matrix connecting two undamaged beam segments. Therefore, the cracks are modelled as a rotational spring. This matrix defines the relationship between the displacements and forces across the crack section and is derived by applying fundamental fracture mechanics theory. We investigated about the effect of the two cracks and a tip mass on the dynamic behavior of a cantilever pipe with a moving mass.