• 대한의생명과학회지
• /
• 제20권3호
• /
• pp.103-110
• /
• 2014

Matrix metalloproteinases (MMPs), also called matrixins, function in the extracellular environment of cells and degrade both matrix and non-matrix proteins. They are multidomain proteins and their activities are regulated by tissue inhibitor of metalloproteinases (TIMPs). The uncontrolled regulation of MMPs is involved in various pathologic processes, such as tumor invasion, migration, host immune escape, extravasation, angiogenesis, and tumor growth. Especially, matrix metalloproteinase-9 (MMP-9) is one of the metastasis-accelerating genes involved in metastasis of various types of human cancers. Here, we review the member of MMP family and discusses their domain structure and function, enzyme activation, the mechanism of inhibition by TIMPs. In particular, we focus the role of MMP-9 in relation to cancer metastasis.

• Steel and Composite Structures
• /
• 재36권6호
• /
• pp.643-656
• /
• 2020

This article presents a comprehensive static analysis of simply supported cross-ply carbon nanotubes reinforced composite (CNTRC) laminated nanobeams under various loading profiles. The nonlocal strain gradient constitutive relation is exploited to present the size-dependence of nano-scale. New higher shear deformation beam theory with hyperbolic function is proposed to satisfy the zero-shear effect at boundaries and parabolic variation through the thickness. Carbon nanotubes (CNTs), as the reinforced elements, are distributed through the beam thickness with different distribution functions, which are, uniform distribution (UD-CNTRC), V- distribution (FG-V CNTRC), O- distribution (FG-O CNTRC) and X- distribution (FG-X CNTRC). The equilibrium equations are derived, and Fourier series function are used to solve the obtained differential equation and get the response of nanobeam under uniform, linear or sinusoidal mechanical loadings. Numerical results are obtained to present influences of CNTs reinforcement patterns, composite laminate structure, nonlocal parameter, length scale parameter, geometric parameters on center deflection ad stresses of CNTRC laminated nanobeams. The proposed model is effective in analysis and design of composite structure ranging from macro-scale to nano-scale.

• 한국환경복원기술학회지
• /
• 제3권1호
• /
• pp.70-79
• /
• 2000

Arbuscular mycorrhizal(AM) fungi have significant role for ecosystem structure and function. They are the major component of forest soil ecosystems and critically important for water and nutrient cycling in the system. To understand the ecology of AM fungi the fungal spores were collected, identified and counted in forest soils under various climatic and edaphic conditions. In relation to soil depth 90% of AM fungi spores and mycorrhizas distributed within 15cm soil depth. Number of spores per $100m{\ell}$ forest soil volume was 5 to 36 spores from 1 to 3 fungal species. AM fungal species diversity was higher in warmer climates, and more moist and fertile soils. The most frequently found species were Gigaspora decipiens irrespective of soil moisture and Gi. gigantea irrespective of soil fertility. In the Jeju island the soils of Cryptomeria japonica plantations and Miscanthus sinensis var. purpurascens meadow had more AM spores than the other soils. We suggest AM fungi be considered as keystones species when restoring a disturbed forest ecosystem.

• 한국수의병리학회지
• /
• 제2권1호
• /
• pp.9-16
• /
• 1998

Apodemus agrarius Pallas has been known to be a reservoir of hanta virus. But there was no report of immune organs. So this study was performed to clarify the relation between Structure and function of immune organ. In the present investigation an immunocytochemistry procedure was used to examine the distribution of T and B cell and macrophage populations in the thymus spleen and lymph nodes. Most of lymphoid organ showed decreased pattern of Ly1 positive T and IgM positive B cells. Macrophage positive cells were deceased in vivo. The present study gives an overview on the immune organ structure and function of Apodemus agrarius Pallas.

• 한국HCI학회:학술대회논문집
• /
• 한국HCI학회 2009년도 학술대회
• /
• pp.1279-1286
• /
• 2009

"Interactivity refers to the possibility of an audience actively participating in the control of an artwork or representation." Andy Cameron, Dissimulations Interaction can be described as a way or function that improves the participation of audiences/viewers to being immersed into the medium itself. Until now, however, in terms of interactive cinema, interaction has not shown a sufficient participation for audiences. Specifically, audiences/viewers described that the structure of storytelling has failed to satisfy their requirements, in order to participate in the structure of storytelling. The aim of the research itself, therefore, began to ask and wonder why audiences/viewers criticised the participation which audiences/viewers are able to control storytelling, in interactive cinema, could not satisfied them in order to control and follow a storyline of interaction. In general idea, in interactive cinema, the function which allows audiences/viewers to be immersed into the storylines, must allow the immediacies of interaction. Audiences/viewers must therefore be able to satisfy the general idea of interactive cinema through controlling the directions of every choice offered. They must also be able to be immersed in the interactive storylines. Which of the prime causes can be improved or re-considered, to satisfy the participation requirements of audiences/viewers? The intention of this research also began to investigate a suitable method of storytelling within a narrative structure of interactive medium (interactive cinema). Through questioning the matter (it will be described in a later chapter), this research will be focused on the relationship between narrative structured interaction and audiences/viewers, which is of prime importance in relation to interaction. To further the research, Pilot study (experiment with the basic interactive narrative structure) was offered in order to understand and maintain a suitable method of storytelling within a narrative structure of interactive cinema and it also was explored to understand how the aim of the research would be maintained for further qualitative research.

• 천문학회보
• /
• 제38권2호
• /
• pp.58.1-58.1
• /
• 2013

The main idea of the Alcock-Paczynski (AP) test is that, if we use a wrong distance-redshift relation to infer the shape of a spherical object in the Universe, this object may look non-spherical. To probe the cosmic expansion history through the AP test, the key point is to find something which is known as spherical in the Universe. We propose two possible ways applying the AP test to the large scale structure (LSS): 1) Based on the observed galaxies or quasars, one built up the beta-skeleton tracing the LSS, and investigating the inhomogeneity of the connections; 2) One reconstructs the smoothed density-contrast gradient field based on LSS observations, and investigating the inhomogeneity of the gradient vectors. Compared with some existed methods probing AP effect through 2-point correlation function, galaxy pairs, or voids, our methods have various advantages: 1) The information of both the high and low dense regions of the LSS are taken into account. 2) The redshift space distortion as the main contamination to the AP effect can be easily removed.

• 한국실내디자인학회논문집
• /
• 제1호
• /
• pp.52-55
• /
• 1992

The purpose of this study was to suggest the spatial structure among residential behaviors in relation to work space. To find the structure, Multi-Dimensional Scaling analysis was used. Respondents were 349 middle income housewives living in apartments in the area of Caopital region. Data were collected through the questinnaire survey. For the future residential interior design, following points were sugtested. A laundary space neess to be developed independently , being separated from both bathroom and kitchen/dining space. A new area which will give housewives some territoriality and also function as home office needs to be considered. A space configuration which satisfies the organic relationships among laundary behaviors such as washing dying, ironing and folding , needs to be systematically planned, with two adjoining separate zones of wet and dry utility . The present bathroom nees to be more incorporated to the private bedroom rather than to workspace.

• 전자공학회논문지A
• /
• 제31A권7호
• /
• pp.36-46
• /
• 1994

In the realization of interface between subscriber and network, D-channel may deteriorate the performance of switching system in handling subscriber. Thus, D-channel must be designd in a way to interface efficiently with the system while maintaining exciting performance. This objective can be obtained by through consideration of the structure of the system. This paper shows the method to design D-channel, which has significant relation with the structure of the system whenrealizing the interface between subscriber and network, in adding ISDN function. The goal of performance is also proposed.

• Journal of Pharmaceutical Investigation
• /
• 제12권4호
• /
• pp.101-111
• /
• 1982

The effect of salt addition to MO-CTB mixed micelle was studied. The logarithm of cmcs obtained from above experiment is a linear function of the logarithm of the sum of the cmc and the concentration of added salt. In order to investigate the relation of the color change and the structure, the measurement of conductance to the mixed micelle has been carried out. To see the color change and conductance data obtained in the present study, structure A is more probable one to the micelles having the ${\lambda}_{max}$ 376nm.

• E2M - 전기 전자와 첨단 소재
• /
• 제10권10호
• /
• pp.989-994
• /
• 1997

In a Guest-Host cell the orientational ordering of dyes doped into liquid crystals has been investigated. To evaluate the influence of the host liquid crystals on the ordering of the dyes we have measured precisely the ordering parameters of the liquid crystals by using the dichroic ratio of the absorbances for infrared light polarized parallel and perpendicular to the diector. Our experimental results show that the ordering of the dyes can be expressed as a function of not only the molecular structure of the dyes but also the order parameter of the liquid crystals. These functions are dependent on the kinds of the liquid crystals and the dyes. Particularly the combination such as anthraquinone dyes doped into cyanobiphenyl liquid crystals show a very high ordering parameter. This is considered due to a strong intermolecular interaction between the dipoles of both liquid crystals and dyes.