• Title/Summary/Keyword: Reinforcement Effects

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Correlative Effects of Yookmijihwangtang(六味地黃湯) on the T helper cell count, Blood cAMP, Testosterone and Cortisol (육미지황탕(六味地黃湯)이 생리활성지표(生理活性指標)와 임파구세포수(淋巴球細胞數)에 미치는 영향(影響))

  • Kim, Young-Kuen;Ryu, Bong-Ha;Park, Dong-Won;Ryu, Ki-Won
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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    • v.4 no.1
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    • pp.89-110
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    • 1998
  • Yookmijihwangtang has been widely used oriental herb prescriptions, which is healing some discuss that come from insufficiency of innate essence and deficiency of kidney Ki. The meaning of healing discusses tonification of insufficient innate essence and insufficient kidney Ki can be regarded as reinforcement of wholely power of keeping homeostasis, that is correlated with immuno-responsibility which protects subject from outer antigen to keep normal vital condition. This study was aimed to investigate correlative effects of Yookmijihwangtang water abstract on the RBC, WBC, blood CD4+ T helper cell count, blood testosterone, blood cAMP and blood cortisol. 40 Sprague-Dawley male rats were divided into 5 groups(Normal, Control, Sample I, Sample II, Sample III), 6 animals in every group. Normal group was not treated anything, control group was administrated normal saline in the same dosage of Sample I. 3 Sample groups were received some of Yookmijihwangtang water abstract at one time per 24 hours during 5 days in different dosage. Sample I(1/310pack/ml), Sample II(1/62pack/ml), Sample III(1/2.4pack/ml). After finishing treatment, all experimental subjects were killed for blood sample on RBC, WBC, blood CD4+ T helper cell count, spleen CD4+ T helper cell count, axillary lymph node CD4+ T helper cell count. blood cAMP, blood testosterone and blood cortisol. The results were as follows; RBC and WBC were increased in all sample groups. Blood CD4+ T helper cell count(CD4+ T cell count in the blood/whole lymphocyte count in the blood ${\times}100%$) was Normal $46.17{\pm}5.88$, Control $44.50{\pm}4.37$, Sample I $53.00{\pm}2.28$, Sample II $53.83{\pm}3.87$, Sample III $52.17{\pm}2.93$. By the 95% Duncan ANOVA all experimental groups(sample I, Sample II, Sample III) showed slight significant difference from Normal and Control. Blood cAMP(nmol/l) were Normal $1.12{\pm}0.17$, Control $1.16{\pm}0.32$, Sample I $0.46{\pm}0.07$, Sample II $0.44{\pm}0.04$, Sample III $0.54{\pm}0.04$. All experimental groups were singificantly different from both Normal and Control groups(p<0.05). Blood cortisol(nl/ml) were Normal $100.00{\pm}2.00$ Control $90.00{\pm}4.00$, Sample I $440.00{\pm}5.00$, Sample II $520.00{\pm}40.00$, Sample III $470.00{\pm}7.00$. Blood cortisol of all experimental groups were significantly increased(p<0.05). The results suggest that Yookmijihwangtang water abstract could be administrated to patients who have some diseases insufficient essence.

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A Structural Model for Quality of Life in Individuals with Rheumatoid Arthritis (류마치스성 관절염 환자의 삶의 질에 대한 구조 모형)

  • 오현수;김영란
    • Journal of Korean Academy of Nursing
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    • v.27 no.3
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    • pp.614-626
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    • 1997
  • The main purposes of the study were to develop and test a model which explains the dynamic relationship among factors reported as affecting to the quality of life of individuals with rheumatoid arthritis and to examine the relationship between self-help response and quaility of life. Data for the study were collected from March 1996 to December 1996 from 153 female patients who regularly visited a clinic for people with rheumatism. The patients were introduced to the investigators by nurses who worked at that clinic, and then the investigator interviewed the patients for 30 to 40 minutes to collect the data. Instruments used in the study were modified self-report questionaires from the ones which were already developed in previous studies or from related literature. Data analysis were performed using LISREL(Lineal Structural Relations) 8 program to test whether the proposed hypothesized model fit the collected data. To test the fitablity of the hypothesized model both a general fit measure and a detailed fit measure were used. Based on the test results from the various fit measures, the hypothesized model was found to be well suited to the real data. As characteristics related to illness becomes severe, the feasibility for these characteristics leading to the perception of uncertainty about the illness tend to increase, but, the direct effects from the illness characteristics(such as level of physical symptoms, sense of social-psychologic change, limitations of action) as they are related to the other intrinsic variables (self-efficacy or self-help behavior and quality of life), were found to be not significant. It was found that uncertainty had a direct effect on self-efficacy but did not have a direct effect on self-help behavior or quality of life. Also, it is noted that self-efficacy had a positive effect on self-help behavior and quality of life and there was a bilateral relationship between self-efficacy and self-help behavior. Lastly, the hypothesis proposed from the theoretical model in this study was supported basis of the results that self-help behavior provides both direct and positive effects to quality of life. Particularity, since a bilateral relationship was also found between self-help behavior and quality of life in the modified model, as self-help behavior increased, so did quality of life. And, reversely, as quality of life increased, so did self-help behavior. In conclusion, the results of this study suggest that focusing on both acquirement and reinforcement of adjustment factors or self-help behavior is more efficient than focusing on the characteristics of illness in establishing the stategies for improving quality of life of individuals with rheumatoid arthritis.

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Effects of Educational Context Variables on Science Achievement and Interest in TIMSS 2015 (TIMSS 2015에서 과학 성취도와 흥미에 영향을 주는 교육맥락변인 분석)

  • Kwak, Youngsun
    • Journal of The Korean Association For Science Education
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    • v.38 no.2
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    • pp.113-122
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    • 2018
  • The purpose of this study is to investigate the effects of the educational context variables on students' science achievement and interest in TIMSS 2015. TIMSS 2015 science data and questionnaire results were used to fit the Hierarchical Linear Model (HLM) in this study. According to the results, books at home, parents' level of education, and students' views on science lessons have significant influence on science achievement of above-high level 4th-grade students, and books at home on below-intermediate level 4th-grade students. Books at home, students' views on science lessons, and school composition by student economic background have significant influence on science achievement of above-high level 8th-grade students, and books at home and students' views on science lessons on science achievement of below-Intermediate level 8th-grade students. In all grade levels, books at home, and students' views on science lessons have significant influence on science achievement and interest. Discussed in the conclusion are ways to improve science teaching and learning including offering systematic reading programs for all students, reinforcement of student-participation in science classes, connecting science hands-on activities with science concepts for below-Intermediate level elementary students, and so on.

Flexural Strength Analysis of RC T-Beams Strengthened Using Fiber Sheets (섬유시트로 보강된 T형 철근콘크리트보의 휨 강도 해석)

  • Park, Tae-Hyo;Lee, Gyu-Chul
    • Journal of the Korea Concrete Institute
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    • v.15 no.2
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    • pp.234-245
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    • 2003
  • Most of the concrete bridge structures are exposed to damage due to the excessive traffic loading and the aging of the structure. The damage of concrete causes the further deterioration of the function in the concrete structure due to corrosion of the reinforced bars and decohesion between the concrete and the reinforced bar. The quick rehabilitation of the damaged concrete structures has become of great importance in the concrete structural system in order to avoid the further deterioration of the structures. Recently fiber sheets are used for strengthening the damaged concrete structures due to its many advantages such as its durability, non-corrosive nature, low weight, ease of application, cost saving, control of crack propagation, strength to thickness ratio, high tensile strength, serviceability and aesthetic. However, the lack of analytical procedures for assessing the nominal moment capacity by the fiber sheet reinforcement leads to difficulties in the effective process of decisions of the factors in the strengthening procedure. In this work, flexural strengthening effects by fiber sheets bonded on bottom face of the member are studied for the reinforced concrete T beam. In addition, auxiliary flexural strengthening effects by U-type fiber sheets bonded on bottom and side faces of the member to prevent delamination of the bottom fiber sheet are theoretically investigated. The analytical solutions are compared with experimental results of several references to verify the proposed approach. It is shown that the good agreements between the predicted results and experimental data are obtained.

The Effects of Self-efficacy, Appearance Satisfaction in Major on Employment Stress of Nursing College Students (간호대학생의 자아존중감, 외모만족도, 전공만족도가 취업스트레스에 미치는 영향)

  • Kim, Kyoung-Nam;Kang, Eun-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.3
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    • pp.80-88
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    • 2020
  • This study aimed to determine the effects of self-esteem, appearance satisfaction, and satisfaction in their major on the employment stress of nursing college students. The subjects were 194 students from four colleges of nursing in P-province in Korea. Data were collected from self-administered questionnaires, t-test, ANOVA, Pearson's and Spearman's correlation coefficients. Multiple regression with dummy variables was used for statistical analysis of the data. The results revealed the following scores: self-esteem 3.40±0.53, appearance satisfaction 2.96±0.56, satisfaction with the major 3.80±0.61, and employment stress 2.23±0.75. Significant differences in employment stress according to general characteristics of subjects were observed in gender (t=7.40, p=.007), entering nursing college motivation (F=3.24, p=.023), and college life satisfaction (F=16.722, p<.001). Employment stress showed a negative correlation with self-esteem (r=-.433, p<.001), appearance satisfaction (r=-.307, p<.001), and satisfaction in major (r=-.534, p<.001). The satisfaction with the major (β=-.371, p<.001), self-esteem (β=-.166, p=.026), appearance satisfaction (β=-.132, p=.045), entering nursing college motivation (β=.163, p=.006), and gender (β=.131, p=.033) confirmed as a factors affecting the employment stress and accounted for 35.6% of the variance. Based on the results, it is necessary to develop employment-competency reinforcement programs to increase the level of satisfaction in the major, appearance satisfaction, and self-esteem to reduce the employment stress of nursing college students.

The Effects of Cure System on Vulcanization Reaction Constant and Physical Properties of Rubber Compounds (가황시스템 변화가 배합고무의 가황반응속도 및 물리적 특성에 미치는 영향)

  • Lee, Seag;Park, Nam Cook
    • Applied Chemistry for Engineering
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    • v.10 no.3
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    • pp.419-426
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    • 1999
  • In this study, the reaction rate constant, activation energy, total crosslinking density, elastic constant, cure properties ($t_5,\;t_{90}$), modulus, and abrasion resistance of rubber compounds were investigated as a function of cure temperatures, cure systems and reinforcing filler loadings. Reaction rate constants showed strong dependence on thc carbon black loading, cure temperature and cure system, and increased sharply with increasing the reaction temperatures. The lowest activation energy was obtained in the efficient cure (EC) system which corresponds to the high level of sulfur to accelerator ratio, and the activation energy was decreased with decreasing the carbon black loadings. The change of carbon black loadings directly affects the modulus and abrasion resistance, but the change of cure system showed various effects on the rubber compounds. Increased carbon black loadings showed the high modulus, improved abrasion resistance and short scorch time but decrease in crosslinking density and elastic constant. Higher crosslinking density and elastic constant were shown in the EC cure system regardless of carbon black loadings, but scorch timc ($t_5$) was not affected by the change of the ratio of sulfur to accelerator. Rapid optimum cure time ($t_{90}$) were showen in the EC cure system. Also, the equivalent cure curve coefficient of rubber compound was 0.96 for conventional cure (CC) system, and 0.94 for semi-efficient cure (SEC) and EC system regardless carbon black loadings. As regarding the abrasion resistance, wear volume showed the logarithmic increase for the loaded weight.

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The Application of Nanoliposome Composed of Ceramide as an Anti-irritant in Cosmetics (세라마이드를 구성성분으로 하는 나노리포좀의 응용 - 화장품에서의 자극완화제)

  • Jo Byoung Kee;Ahn Gi Woong;Shin Bong Soo;Jeong Ji Hean;Park Hae-Ryong;Hwang Yong-Il
    • Journal of Life Science
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    • v.15 no.2 s.69
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    • pp.267-272
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    • 2005
  • The objective of this study is to suggest the potentialities of nanoliposome composed of ceramide as an anti-irritant against various irritants used in cosmetics. Ceramides are major structural components of the epidermal permeability barrier, which is known to play an essential part in human physiology by not only preventing the loss of water from the body but also protecting the body from external physical, chemical, and microbial insults. According to the results, better effects on reinforcement of skin barrier function and anti-irritation were obtained with nanoliposome composed of ceramide than with dispersed ceramide. And, we performed in vitro skin penetration test using horizontal Franz diffusion cells with skin membrane prepared from hairless mouse to evaluate the influence of nanoliposome composed of ceramide on the skin penetration of lactic acid in formulations. From the results, we found that the anti-irritation effects of nanoliposome containing ceramide were due to reduced penetration rate of irritants. Conclusively, we could develop a new anti-irritation system and apply this nanoliposome composed of ceramide to the final cosmetic products successfully.

Development of an Infants' Sleep Health Program Using a Video for SIDS Prevention Education and Measurement of the Program's Effects (영아 수면건강 교육프로그램의 개발 및 효과)

  • Jang, Sook;Kim, Il-Ok
    • Child Health Nursing Research
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    • v.21 no.1
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    • pp.11-19
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    • 2015
  • Purpose: The purposes of this study were to develop an infant sleep health education program using a video for SIDS prevention education and to measure the effects of the program. Methods: The infant sleep health education program consisted of presentations and motor images. The formation of educational material was directed by the systematic design of instruction. Participants in this study were 59 primiparous women from postpartum care centers. The instruments used in this study were criterion referenced test items for knowledge about infant sleep health and confidence inventory. Experimental group I was given the treatment of infant sleep health education program. Experimental group II was given the program using a video reinforcement after 2 weeks. On the other hand, control group was given no treatment. Results: There was a significant increase in knowledge and confidence in the performance of mother's roles of both experimental group I and experimental group II over the control group. No significant difference was founds for knowledge and confidence in the performance of mother's roles between experimental group I and II. Conclusion: The results indicate that this program is a very effective intervention for better sleep health in infants by helping the mothers increase confidence in their role performance.

A Study of the Therapeutic Effects of Ginseng on Chi-deficiency Syndrome with Sphygmography (맥파계법을 이용한 인삼의 기부족 증상 치료효과에 관한 연구)

  • Chang Hen-Hong;Shen Yung-Yu;Chan Yat-Kwong;Wang Shu-Yu;Ma Chien-Chung
    • Proceedings of the Ginseng society Conference
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    • 1988.08a
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    • pp.70-76
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    • 1988
  • Since ancient times, records pertaining to chi-reinforecenent of ginseng have been documented in books of Chinese nedicine. We, therefore, assessed the therapeutic effects of ginseng on patients with chi-deficiency syndrome. Eigheen cases of chi-deficiency, screened at the outpatient service in the internal department of Chinse medicine at the China Medical College Hospital. were prescribed two grams of Korean red ginseng powder three times daily for a two week period. For evaluation, a questionnaire and diagnosis by sphygmography were conducted prior to and after administration of the prescription. For control purposes, fourteen volunteers fasted for more than five days (seven had access only to ginseng. and the other seven were given only mineral water) and were subsequently evaluated by the same criteria. Three results were obtained for the ginseng treated group: (1) improvements in symptoms of chi-deficiency such as fatigue and dizziness; (2) changes in pulse waves with time domains showing alternate P-waves, strengthened dicrotic waves, and some minute waves in the end-diastolic period; (3) frequency domains with enhanced amplitudes around 12Hz. These three findings, which are consistent with each other, suggest the reinforcement of the effect of ginseng on 'heart-spleen chi' in Chinese medicine.

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Reinforcement of Antioxidative Potentials by Korean Traditional Prescriptions on Mouse Plasma and Liver (전통 한약 탕제 투여에 의한 혈장 및 간 조직의 항산화력 증강 효과)

  • Hong, Seong-Gil;Lee, Mi-Young;Yoon, Yoo-Sik;Kang, Bong-Joo;Kim, Dae-Won;Cho, Dong-Wuk
    • Korean Journal of Food Science and Technology
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    • v.31 no.6
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    • pp.1661-1666
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    • 1999
  • Yungmijihwgang-Won, Yollyunggobon-Dan and Palmi-Hwan, Korea traditional prescriptions composed of oriental medical herbs, have been used successfully to improve human health and regimen. This study was designed to examine the mechanism of healthful effects of the Korea traditional prescriptions through its antioxidative potentials. Using in vitro antioxidative activity assay system such as DPPH radical quenching assay, superoxide anion radical scavenging assay and inhibition of TBARS production, three Korea traditional prescriptions were observed to have nearly the same antioxidative potentials as ascorbic acid, a well-known strong water-soluble antioxidant. Moreover, we observed reinforced antioxidative effects of these drugs in liver from mouse fed these drugs with 4 weeks. When liver homogenate was incubated with 2.2'-azobis(amidinopropane) dihydrochloride(AAPH), as a free radical initiator, we observed that oxidative damages were decreased and antioxidative potentials were increased in liver homogenate treated these drugs. However, enzymatic antioxidative system as superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase was not affected by drug administration.

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