• Physical Therapy Korea
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• v.22 no.4
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• pp.8-16
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• 2015

The purpose of this study was to evaluate the effects of mobilization of the sciatic nerve on hamstring flexibility, lower limb strength, and gait performance in patients with chronic stroke. This study was a randomized clinical trial with a crossover design. Sixteen subjects were recruited for this study. The subjects were randomly divided into two intervention groups and underwent either of the following two interventions: sciatic nerve mobilization or static stretching of the hamstring. We assessed hamstring flexibility, lower limb strength, and gait performance using a digital inclinometer, a hand-held dynamometer, and the 10-meter walk test, respectively. Subjects had a 24-hour rest period between each session in order to minimize carryover effects. Measurements for each test were assessed prior to and immediately after the intervention sessions. Using a two-way analysis of variance test with repeated measures, data from the two trials were analyzed by comparing the differences between both techniques. The level of statistical significance was set at .05. Sciatic nerve mobilization resulted in significantly better knee extensor strength (p=.023, from $15.32{\pm}5.98$ to $18.16{\pm}6.95kg$) and knee flexor strength (p=.011, from $7.80{\pm}4.80$ to $8.15{\pm}4.24kg$) in the experimental group than in the control group. However, no significant effects of static stretching of the hamstring were observed on hamstring flexibility from the ankle plantar flexion (p=.966) and ankle neutral positions (p=.210) and on gait performance (p=.396). This study indicated that the sciatic nerve mobilization technique may be more effective in muscle activation of the knee extensor muscle and knee flexor muscle than hamstring static stretching technique in patients with chronic stroke.

• The Journal of Korean society of community based occupational therapy
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• v.4 no.2
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• pp.53-61
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• 2014

Objective : The purpose of this study was to examine the effects of video observation training on neglect and ability to perform activities of daily living of stroke patients. Methods : Patients diagnosed with stroke were selected as subjects according to criteria to select the research targets. The additional video observation training besides OT and PT was carried out to 15 patients in an experimental group and sham therapy besides OT and PT was performed to 15 patients in a control group. Line-bisection test were conducted to compare the neglect before and after therapy intervention and FIM was conducted to compare the ability to perform the activities of daily living. Results : The result of this study that we found out that degree of neglect in an experimental group where video observation training was carried out improved neglect and the ability to perform activities of daily living. Conclusion : The video observation training the video observation training is expected to be useful in clinics.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.25 no.1
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• pp.63-70
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• 2019

Background: The purpose of this study was to determine the effects of a pelvic compression belt on gait abilities and balance in subacute stroke patients. Methods: Twenty two patients with subacute were recruited and randomly assigned into two group: Two group offered conventional physical therapy and occupational therapy for five day. The group was composed of twelve patients. Participants in the experimental group were given the pelvic compression belt and conventional physical therapy, conventional occupational therapy, although conventional physical therapy and occupational therapy provided in the subjects in the control group. To assess the gait ability, the GAITRITE system was used and the Balance system SD was used to test balance. All measurements were performed before and after intervention. Results: The experimental group shows a significant improvement the cadence, velocity, step length and stride length in gait (p<.05) and show significant increase in the dynamic standing balance (p<.05). However, control group shows a significant improvement the cadence, velocity, step length and stride length in gait (p<.05), but shows no significant differences in dynamic standing balance. Furthermore, there were significant differences gait velocity, dynamic standing balance between two groups (p<.05). Conclusions: The results demonstrated that the elastic pelvic belt application is effective to improve gait velocity, dynamic balance in the subacute stroke patients. Thus, the elastic pelvic belt is seemed to be one of the potential methods to facilitate the active rehabilitation program for hemiplegia patients.

• Journal of Korean Neurosurgical Society
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• v.67 no.5
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• pp.568-577
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• 2024

Objective : Post-stroke shoulder pain (PSSP) is a common complication that limits the range of motion (ROM) of the shoulder, the patient's rehabilitation and in turn, affects the patients' quality of life (QoL). Several treatment modalities such as sling, positioning, strapping, functional electrical stimulation, and nerve block have been suggested in literatures, however none of the treatments had long-term effects for PSSP. In this study, the authors evaluated clinical efficacy of pulsed radiofrequency (PRF) neuromodulation on the suprascapular nerve for PSSP, and suggested it as a potential treatment with long-term effect. Methods : This retrospective case series was conducted at a single center, a private practice institution. From 2013 to 2021, 13 patients with PSSP underwent PRF neuromodulation of the suprascapular nerve. The primary outcome measure was the Visual analog scale (VAS) score. The secondary outcome measurements included the shoulder ROM, Disability assessment scale (DAS), modified Ashworth scale, modified Rankin scale (mRS), and EuroQol-5 dimension-3L questionnaire (EQ-5D-3L) scores. These parameters were evaluated before PRF modulation, immediately after PRF modulation, and every 3 months until the final follow-up visit. Results : Six men and seven women were enrolled, and all patients were followed-up for a minimum of 12 months. The mean VAS score was 7.07 points before PRF neuromodulation and 2.38 points immediately post-procedure. Shoulder ROM for abduction and flexion, DAS for pain, mRS, and EQ-5D-3L demonstrated marked improvement. No complications were reported. Conclusion : PRF neuromodulation of the suprascapular nerve is an effective modality in patients with PSSP, and has long-term effect of pain relief, improvement of QoL.

• Physical Therapy Korea
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• v.14 no.1
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• pp.46-54
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• 2007

The purposes of the present study were to determine the difference of functional outcome, and to identify factors associated with functional difference in patients with stroke. The sample consisted of 56 stroke patients who had received physical therapy at the physical therapy unit of the Dongeui Medical Center in Busan city between January 2000 and June 2002. Stroke patients were evaluated by physical therapists 3 times; The first day in physical therapy (PT) (T1), one month after the first day in PT (T2), and two months after the first day in PT (T3). Functional status was assessed with the Functional Independence Measure (FIM) instrument, a validated instrument for documenting the severity of disability and assessing the outcome of rehabilitation treatment. Functional gain was calculated over T2-T1, T3-T1, and T3-T2. SAS statistical software was used for the analysis. The Student's t-test, paired t-test, analysis of variance (ANOVA/Tukey and Scheffe), and analysis of covariance (ANCOVA) were used to examine the functional difference in variables. Repeated measures ANOVA was also used to analyze the functional difference by time (T1, T2, and T3). Multiple regression analysis was performed to determine the effects of independent variables on the difference of functional outcome as defined by the FIM score. A total of 56 stroke patients were evaluated, their average age${\pm}$standard deviation was $61.6{\pm}9.3$ years (range: 40~81 yr). The functional status of patients who received physical therapy for about 2~3 months was significantly improved (mean FIM scores, $20.5{\pm}1.8$, $28.9{\pm}1.9$, and $8.41{\pm}1.1$ points for each time period, respectively) (p<.0001). Diabetes was significantly associated with the FIM score for T2-T1 (p<.05). The type of diagnosis was significantly associated with the FIM score for T3-T1 (p<.05). Gender, smoking, and the FIM score on admission were significantly associated with the FIM score for T3-T2 (p<.05). In conclusion, gender, smoking, diabetes, the type of diagnosis, and the FIM score on admission were significantly associated with improved FIM scores. We recommend that further research should explore the functional outcome by using larger sample sizes, longer follow-up periods, and more sensitive assessment instruments.

• The Journal of the Korea institute of electronic communication sciences
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• v.13 no.6
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• pp.1387-1396
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• 2018

The purpose of this study was examined the effect of Tabata exercise using health care application on balance, gait and activities of daily living in patients with stroke. Twenty patients with stroke were participated patients with stroke in this study. Nineteen participants were randomly allocated to ten in experimental and nine in control groups. The both groups received the rehabilitation therapy during for 4 weeks. The experimental group performed Tabata exercise based on health care application, supervised under caregivers, during 30 min/day. The control group performed self-exercise supervised under caregivers, during 30 min/day. Both groups exercised for 4 weeks, 3 times a week, 30 min/day. Tabata exercise was trained by an physical and occupational therapists. The outcome measures were the BBS(: Berg Balance Scale), TUG(: Timed Up and Go, K-MBI(: Korean Modified Barthel Index). In results, the experimental groups showed a significant improvements after intervention in all assessments(p<.05), The control groups showed a significant improvements after intervention in BBS(p<.05) The experimental group showed a greater significant improvements than control group in TUG, BBS, K-MBI(p<.05). We suggest that Tabata exercise using health care application can have a effects of the improvements of balance, gait and activities of daily living than only self-exercise in patients with stroke.

• The Journal of Korea CHUNA Manual Medicine
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• v.3 no.1
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• pp.55-64
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• 2002

Objectives : Acupuncture therapy is known as a effective method to CVA with paralysis. To make clear about effectiveness of acupuncture affecting to active and static postural adaptation for the patient with hemiparesis, we studied whether acupuncture changed ability of maintenance with one leg standing posture, and character of gait such as gait velocity, cadence, stride length, step length and base of support. Methods : This clinical study has been carried out with 10 cases of CVA patient with hemiparesis. We treated patients with acupuncture for 4 weeks, estimated each paralytic leg and well leg before 1st treatment and after last treatment, and compared the change of one leg with the other. To estimate the change of ability of static postural adaptation, we checked the time of duration with one leg standing posture. And about active postural adaptation, we used temporal distance gait analysis with Ink-Foot-Print method. Results and Conclusions : In static postural adaptation, paralytic leg significantly improved the duration with one leg posture. And In active postural adaptation with gait analysis, paralytic leg showed significant improvement in stride length and step length. Base of support and cadence were also significantly improved.

• Journal of Korean Medicine Rehabilitation
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• v.19 no.2
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• pp.103-112
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• 2009

Objectives : This study was to evaluate the pharmacological effect of Korea Red Ginseng aqueous extract (KRGE) on serum-deprived apoptosis of neuronal-like pheochromocytoma PC12 cells and to investigate its underlying action mechanism. Methods : KRGE was prepared by extracting Korea Red Ginseng with hot water and concentrating using a vacuum evaporator. Cell viability was determined after incubation of cells with KRGE or chemical inhibitor in serum-deprived medium for 60 h by counting intact nuclei following lysing of the cell membrane. Caspase activities were measured using chromogenic substrates and signal-associated protein phosphorylation and cytochrome c release were determined by Western blot analyses using their specific antibodies. Results : Serum deprivation induced PC12 cell death, which was accompanied by typical morphological features of apoptotic cell, such as nuclear fragmentation, caspase-3 activation, and cytochrome c release. This apoptotic cell death was significantly inhibited by KRGE and caspase-3 inhibitor, but not by the addition of NMA, ODQ, and PD98059. KRGE promoted phosphorylation of Akt and Bad, and this phosphorylation was inhibited by the PI3K inhibitor LY92004. In addition, this inhibitor also reversed KRGE-mediated protection of PC 12 cells from serum deprivation. These results suggested that KRGE protects PC12 cells from serum deprivation-induced apoptosis through the activation of PI3K/Akt-dependent Bad phosphorylation and cytochrome c release, resulting in caspase-3 activation. Conclusions : KRGE should be considered as a potential therapeutic drug for brain diseases including stroke induced by apoptosis of neuronal cells.

• Korean Journal of Clinical Laboratory Science
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• v.47 no.2
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• pp.90-95
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• 2015

The purpose of this study was to investigate the effects of exercise through an in-hospital rehabilitation program on the enhanced immunity of immune cells and on the reduction of serum Cortisol, an indicator of physiological stress responses, among stroke patients. The 25 subjects were put to the program for two years from March 2, 2013 to February 28, 2015. The experimental group included 13 stroke patients from S and C Hospital in Gwangju, and the control group was composed of 12 common people. The findings were as follows: there were no significant differences in T cells between the experimental group with $69.18{\pm}11.78%$ and the control group with $70.75{\pm}6.33%$; there were significant differences in B cells between the experimental group ($12.95{\pm}3.74%$) and the control group ($16.27{\pm}3.49%$). Furthermore, there were no statistically significant increases of NK cells between the experimental group ($21.98{\pm}8.98%$) and the control group ($15.72{\pm}5.07%$) with p<0.05, though the values for the experimental group did rise. While there was elevated Cortisol before exercise in the experimental group (p<0.05), which recorded $13.65{\pm}6.85%$ before and $9.90{\pm}4.66%$ after, there were no differences in the control group, which recorded $11.635{\pm}4.02%$ before and $12.64{\pm}2.30%$ after exercise. The present study also found continued exercise through an in-hospital rehabilitation exercise program increased differences in NK and T cells before and after exercise in the experimental group and thus had effects on enhanced immunity. Meanwhile, differences in Cortisol before and after exercise in the experimental group decreased, which indicates that the continued exercise was effective in reducing stress.

• The Journal of Korean Medicine
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• v.15 no.2 s.28
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• pp.46-91
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• 1994

l. Backgrounds of Studies Cerebrovascular accident. one of the three major causes of death among audults with cardiopathy and malignancy, has been on the increase in korea while it is on the decrease in European countries and Japan. Types of stroke undergo changes caused by prolongment of life expectancy. and social and economic variety. More patients of ischemic stroke show a tendency to increase now than those of hemorrhagic stroke in the past. Many clinical studies on medical cerebrovascular and oriental stroke of paralysis have been published. but few clinical studies on therapeutics of integrated oriental and western medicine are to be found. So I have made an attempt to study clinical observations and therapeutic responses of ischemic stroke under integrated oriental and western medicine. 2.Methods. Among the patients admitted into the clinic of Joong-Poong, Woo-Suk University Hospital from May 1. 1993 until April 30. 1994 those 56 patients who were diagnosed as ischemic stroke on Computed Tomography(CT) and showed no dubious symptom after examination of coagulation and bleeding time were classified into the following six steps and treated: l)diagnosis 2)emergency treatment 3)basic treatment 4)treatment of risk and provoking factors. and preceeding disease 5)complications and conservative therapy 6)rehabilitation. For a period of basic treatment both herb medication and urokinase therapy were applied at the same time. Intravenous injection has been given at a unit of 300.000 dosage a day as urokinase therapy during basic treatment. If they showed any dubious symptom in glucose tolerance test. fructose 500ml and urokinase 300.000 dosage were mixed and injected. In case of no symptom 5% DW 500ml was mixed with urokinase 300.000 unit. and injected at a speed of 15gtt per minute. 3. Results and Conclusions 1) The level of ambulation has been improved from 42.9% when admitted to 73.2% when discharged in the degree of recovery. The level of severe function disorder has been remarkably decreased from 55.4% when admitted to 19.6% when discharged. 2) The treatment effect on the basis of therapeutic response of clinical and subjective symptom shows as follows: 7.1% Excellent. 35.7% Good. 37.5% Effective. 10.7% Stationary. and 8.9% Aggravated. The total recovery above effective shows 80.3%. Judging from the above results I think it proper to develop the model of better preventing and treating ischemic stroke through effective therapeutic and clinical studies of integrated oriental and western medicine.