• Journal of Energy Engineering
• /
• v.25 no.1
• /
• pp.15-22
• /
• 2016

The heat transport system transients of Wolsong 2,3,4 nuclear power plants were analysed during abnormal operating conditions. The compliance with requirements of AECB Regulatory Document R-77 for CANDU reactor was estimated. The analysis results showed that for each postulated accident the peak pressure values in the reactor headers are within the acceptance criteria given in ASME code requirements. The effect of LRV that is one of the overpressure protection device was very minor.

• 시스템엔지니어링워크숍
• /
• s.1
• /
• pp.65-68
• /
• 2003

The air separation plants in the POSCO's Gwangyang Steel Works require high standard on quality as well as reliability as they have to continuously supply essential utility gases as oxygen, nitrogen and argon. And the plants are in the category of high pressure gas systems by the regulatory guidelines, which signifies that they have to maintain utmost level of safety. As an effort to systematically understand and calculate the risk potentials in the air separation plants, risk assessments have been performed on a phased approach: qualitative and followed by quantitative POSCO has chosen to use hazard and operability study and fault tree analysis to satisfy the requirement. As a result, the risk assessment team has identified number of safety and operability related findings. With importance of each and ever findings calculated, a priority list for what/when to do for them could have been presented on a balance fashion.

• Proceedings of the KSME Conference
• /
• 2001.11a
• /
• pp.16-21
• /
• 2001

The PTS reference temperature of reactor pressure vessel for one of the Korean NPPs has been predicted to exceed the screening criteria before it reaches it's design life. To cope with this issue, a plant-specific PTS analysis had been performed in accordance with the Regulatory Guide 1.154 in 1999. As a result of that analysis, it was found that current methodology of RG. 1.154 was very conservative. The objective of this study is to examine the effects of changing various input parameters and to determine the amount of conservatism of the current PTS analysis method. To do this, based on the past PTS analysis experience, parametric study were performed for various models using modified VISA-II code. This paper discusses the analysis results and recommendations to reduce the conservatism of current analysis method.

• Proceedings of the Korean Biophysical Society Conference
• /
• 2001.06a
• /
• pp.57-57
• /
• 2001

Intracellular pH(pH$\sub$i/) is strictly regulated since it is related to various cellular events such as contractility, signal transduction, ion regulation, cell volume, and energy production etc. In physiological conditions, pH$\sub$i/ of arteriolar smooth muscle faced substantial pressure to be changed during the regulation of blood flow. Therefore it is very important to know the regulatory mechanism of pH$\sub$i/.(omitted)

• Nuclear Engineering and Technology
• /
• v.50 no.2
• /
• pp.306-312
• /
• 2018

There is an increasing need in the United States and around the world to move used nuclear fuel from wet storage in fuel pools to dry storage in casks stored at independent spent fuel storage installations or interim storage sites. Under normal conditions, the Nuclear Regulatory Commission limits cladding temperature to $400^{\circ}C$ for high-burnup (>45 GWd/mtU) fuel, with higher temperatures allowed for low-burnup fuel. An analysis was conducted with FRAPCON-4.0 on three modern fuel designs with three representative used nuclear fuel storage temperature profiles that peaked at $400^{\circ}C$. Results were representative of the majority of US light water reactor fuel. They conservatively showed that hoop stress remains below 90 MPa at the licensing temperature limit. Results also show that the limiting case for hoop stress may not be at the highest rod internal pressure in all cases but will be related to the axial temperature and oxidation profiles of the rods at the end of life and in storage.

• Animal cells and systems
• /
• v.15 no.2
• /
• pp.155-159
• /
• 2011

Doublecortin (DCX) is microtubule-associated protein and is required for neuronal migration, differentiation and plasticity. In the retina, it is highly expressed between embryonic day 18 (E18) and E20, and is poorly expressed postnatally. In this study, we investigated the expression and cellular localization of DCX in the rat retina following ischemia induced by transiently increasing the intraocular pressure. While DCX immunoreactivity in control retinas was restricted to the outer border of the inner nuclear layer, it appeared in horizontal cell somata and processes in affected retinas. Quantitative evaluation by immunoblotting confirmed that DCX expression continuously increased after ischemia-reperfusion and showed 370% of control protein levels at 4 weeks after ischemic insult. These results suggest that the DCX in horizontal cells might play a role in neurite remodeling or modulating other neurons in ischemic rat retinas.

• Nuclear Engineering and Technology
• /
• v.49 no.4
• /
• pp.760-768
• /
• 2017

The transition temperature shift (TTS) of the reactor pressure vessel materials is an important factor that determines the lifetime of a nuclear power plant. The prediction of the TTS at the end of a plant's lifespan is calculated based on the equation of Regulatory Guide 1.99 revision 2 (RG1.99/2) from the US. The fluence factor in the equation was expressed as a power function, and the exponent value was determined by the early surveillance data in the US. Recently, an advanced approach to estimate the TTS was proposed in various countries for nuclear power plants, and Korea is considering the development of a new TTS model. In this study, the TTS trend of the Korean surveillance test results was analyzed using a nonlinear regression model and a mixed-effect model based on the power function. The nonlinear regression model yielded a similar exponent as the power function in the fluence compared with RG1.99/2. The mixed-effect model had a higher value of the exponent and showed superior goodness of fit compared with the nonlinear regression model. Compared with RG1.99/2 and RG1.99/3, the mixed-effect model provided a more accurate prediction of the TTS.

• International Journal of Computer Science & Network Security
• /
• v.22 no.10
• /
• pp.57-66
• /
• 2022

The aim of the article is to investigate socio-political processes in Ukraine on the basis of institutional and behavioral approaches, in particular their regulatory and informational support. Methodology. To determine the nature and content of sociopolitical processes, the following approaches have been used: 1. Institutional approach in order to analyze the development of Ukraine's political institutions. 2. The behavioral approach has been used for the analysis of socio-political processes in Ukraine in the context of political behavior of citizens, their political activity which forms the political culture of the country. Results. The general features of the socio-political situation in Ukraine are as follows: the formed model of government, which can be conditionally described as "presidential"; public demand for new leaders remains at a high level; the society has no common vision of further development; significant tendency of reduction of real incomes of a significant part of the society and strengthening of fiscal pressure on businessmen will get a public response after some time. Increasing levels of voice, accountability, efficiency of governance and the quality of the regulatory environment indicate a slow change in the political system, which will have a positive impact on public sentiment in the future. At the same time, there has been little change in the quality of Ukraine's institutions to ensure political stability, the rule of law and control of corruption. There are no cardinal changes in the development of the institution of property rights, protection of intellectual rights, changes in the sphere of ethics and control of corruption. Thus, Ukraine's political institutions have not been able to bring about any change in the social-political processes. Accordingly, an average level of trust and confidence of citizens in political institutions and negative public sentiment regarding their perception and future change can be traced in Ukraine.

• The Korean Journal of Physiology and Pharmacology
• /
• v.1 no.1
• /
• pp.79-82
• /
• 1997

The present study was aimed to explore an interaction between endothelium-derived nitric oxide (NO) and atrial natriuretic peptide (ANP) systems in normotensive and hypertensive states. Rats were made two-kidney, one clip (2K1C) hypertensive and supplemented with either $N^G-nitro-L-arginine$ methyl ester (L-NAME, 5 mg/100 ml drinking water) or L-arginine hydrochloride (400 mg/100 ml drinking water). One group supplied with normal tap water served as control. Sham-clipped rats were also divided into the L-NAME, L-arginine, and control groups. The plasma levels and atrial contents of ANP were determined at day 28 following clipping the renal artery. In 2K1C rats, the plasma level of ANP was higher and the atrial content was lower than in the sham-clipped control. L-Arginine increased the atrial content of ANP in association with a decreased plasma ANP, whereas L-NAME significantly affected neither parameter. The increase of blood pressure in 2K1C rats was not affected by L-arginine or L-NAME. In sham-clipped rats, the plasma level of ANP was significantly increased by L-NAME along with an increase in blood pressure. On the contrary, L-arginine did not affect the blood pressure or plasma ANP. The atrial content of ANP was significantly altered neither by L-arginine nor by L-NAME. These results suggest that NO plays a tonic inhibitory role on the ANP release with concomitant increases of the atrial tissue content. In addition, hypertension is suggested to modify the release and tissue storage of ANP.

• The Korean Journal of Physiology
• /
• v.24 no.2
• /
• pp.403-411
• /
• 1990

The present investigation was performed to see a possible influence of the dorsal raphe nucleus (DRN) on pancreatic exocrine secretion in anesthetized rats since the DRN had been known to exert a regulatory mechanism on sympathetic activity which was known to be very important for pancreatic exocrine secretion, particularly in rats. Twenty-nine Sprague-Dawley rats fasted for 24 hours were anesthetized by i.p. injection of 1 g/kg of urethane. The pancreatic duct was cannulated to collect pancreatic juice while bile juice was diverted into the jejunum. The duodenopyloric junction was tightly ligated. After surgery for collection of pancreatic exocrine secretion and recording of carotid blood pressure, a coaxial electrode was stereotaxically inserted in the DRN with a guide of a brain atlas. And then, electrical stimulus of biphasic square wave with 2 v, 2 msec, 40 Hz was applied on the electrode for 10 minutes. Pancreatic volume flow and protein output secreted in 10 min were measured. Either bilateral cervical vagotomy or spinal cord transection at the level of $C4{\sim}C5$ was performed 20 min prior to stimulation of the DRN. 1) Electrical stimulation of the DRN resulted in significant (p<0.05) increase in pancreatic volume flow and protein output. These stimulatory effects were not affected by cervical vagotomy but completely abolished by cervical cord transection. 2) Electrical stimulation of the DRN also resulted in significant (p<0.05) rise of blood pressure of the carotid artery. The hypertensive effect was not affected by cervical vagotomy but completely abolished by cervical cord transection. The results strongly suggest that the DRN, a part of the central serotonergic system, could exert a stimulatory influence on pancreatic exocrine secretion by increasing the sympathetic activity in anesthetized rats.