• Asian Pacific Journal of Cancer Prevention
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• v.14 no.6
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• pp.3921-3924
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• 2013

Background: To investigate the role of surgical treatment for locally advanced esophageal cancer, we compared the outcomes of chemoradiotheroy alone (CRT) to postoperative chemoradiotherapy (S/CRT), using, Regional Radiotherapy Center, database. Materials and Methods: This retrospective study was conducted in North-West of Iran, included of 255 consecutive patients with esophageal cancer. Eligible operable and non-operable, were treated with S/CRT and CRT respectively. Radiotherapy (RT) was delivered at 1.8-2 Gy/day for five consecutive days in a given week. Chemotherapy (CT) consisted of cisplatin and 5-fluorouracil. Results: From March 2006 to March 2011 255 patients: male/female 129/96, median age 68 (35-90), squamous/adeno 213/12, received CRT/S+CRT 166/59, median radiation dose $45{\pm}13.6Gy$, Median survival 13.5 (11-15), overall survival (OS) One/Two/Three 57/21/16%, Died/alive 158/97, Univariate analysis prognostic factors: age/stag/differentiation/dose of RT/fraction/treatment, Multivariate analysis predictor factor: dose of RT/fraction. Conclusions: Although this treatment offers some possibility for improvement of patients with esophageal cancer, there remains a significant need for development of new drug and new therapeutic approaches that can substantially impact survival.

• Journal of the Korean Association of Geographic Information Studies
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• v.20 no.3
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• pp.42-51
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• 2017

Snowfall is an important natural hazard in Korea. In recent years, the socioeconomic importance of impact-based forecasts of meteorological phenomena have been highlighted. To further develop forecasts, we first need to analyze the climatic characteristics of each region. In this study, homogeneous regions for snowfall analysis were classified using a self-organizing map for impact-based forecast and warning services. Homogeneous regions of snowfall were analyzed into seven clusters and the characteristics of each group were investigated using snowfall, observation days, and maximum snowfall. Daegwallyeong, Gangneung-si, and Jeongeup-si were classified as areas with high snowfall and Gyeongsangdo was classified as an area with low snowfall. Comparison with previous studies showed that representative areas were well distinguished, but snowfall characteristics were found to be different. The results of this study are of relevance to future policy decisions that use impact-based forecasting in each region.

• Journal of Oriental Neuropsychiatry
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• v.8 no.2
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• pp.85-95
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• 1997

After performing the auricular acupuncture therapy for the functional headache, we came to gain the following therapy effects. 1. In the whole of the patients of the functional headache, housewives of forties were most of all. 2. In the classification of mordern medicine on the patients of the functional headache, muscular contractional headache was most of all and in the classification of oriental differentiation of symtoms and signs(辨證), headache due to deficiency of blood(血虛頭痛) was most of all. 3. In the regional auricular acupuncture therapy for the functonal headache, Taiyang of auricular point(太陽點) had an effect on the lateral headache around the area of Taiyang of auricular point(太陽點) though the actions of sedation, analgesia, Neck of auricular point(頸點) had an effect on the muscular contractional headache of the occipital region, and Stomach of auricular point(胃點) had an effect on the headache of stagnation of phlegm(痰濁頭痛) of anterior region with a chronic digestive disease. 4. The average treatment times of the auricular acupuncture therapy in the patients of the functional headache was 4.08 times, if we have them take auricular acupuncture therapy about 4 times it could be thought to take excellent effect of treatment. 5. The effect of auricular acupuncture therapy for functional headache was turned out to be effective in the following orders ; lateral region(Group A), occipital region(Group B), anterior region(group C). Through the clinical consequences of therapy mentioned above, we came to confirm regular therapeuric effects and hereafter, it is considered that a clinical comparative study on oriental cure and auricular acupuncture therapy for headache has to be more progressed than now.

• Journal of the Economic Geographical Society of Korea
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• v.14 no.2
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• pp.129-142
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• 2011

This study investigates the patterns of labor market polarization and analyzes the characteristics and roles of regional labor market in the structuring process of the polarization in the metropolitan areas of Korea. The labor market polarization plays a role of key mechanism for deepening social exclusion in the area through expanding low-pay jobs and working poor. It is of great significance to adopt a spatial approach of local labor market in order to understand underlying dynamics of labor market polarization. Especially it is necessary to develop a more differentiated and systematic policy options based on the analysis of labor market polarization in the metropolitan areas of Korea. It is because understanding spatial differentiation of labor market dynamics is essential to figure out the structuring processes of poverty and sociall exclusion in the metropolican labor market in Korea.

• The Journal of the Korea Contents Association
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• v.11 no.6
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• pp.127-134
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• 2011

A local festival is to be an essential element for the revival of regional economy and marketing since the management concept have introduced in the local government. Each local government is trying to achieve a maximum of efficiency at short period of time. But, most festival are each similar and common. In Asancity, it was holding the 'Great Admiral Yisunsin Festival' every year in April. It has grown into a representative historical figure festival nationally, but can't get over the limitation of historical figure festival. For differentiation from other festivals, The Asancity developed a online game in collaboration with hoseo university game engineering. The e-sports competition with this game was held, as a result, Many youths whose are a neglected class of people on the festival came in the festival and this e-sports competition has become benchmark for many local governments.

• Environmental and Resource Economics Review
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• v.25 no.3
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• pp.351-376
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• 2016

This study examines optimal emission taxes and welfares in mixed duopoly markets where public and private firms produce differentiated goods and emit pollutions. Both comparing quantity and price competitions and comparing simultaneous and simultaneous games provides the followings findings: First, irrespective of competition modes between quantity and price competitions or simultaneous and sequential games, the optimal emission tax is always lower than marginal environmental damage. Second, emission tax under private leadership is the highest in quantity competition while that under public leadership is the highest in price competition. Third, environmental damage under Cournot and private leadership is worsened in quantity competition while that under public leadership is worsened in price competition. Finally, welfare under Bertrand and public leadership is improved in price competition while that under private leadership is improved in quantity competition.

• The Journal of Pediatrics of Korean Medicine
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• v.18 no.2
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• pp.127-142
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• 2004

Objective : To evaluate the effect of Oriental medical treatment on a patient with Ramsay Hunt syndrome with poor prognosis on EMG. Methods : We applied various methods of Oriental Medical treatment including Acupuncture, Electroacupuncture, Herb medicine, Vesiculation therapy using Mylabris and Crontonis Fructus, Massage, Self-excercise of face muscles. Results : 1. Herb medicine was applied on the basis of Differentiation of Syndromes(辨證): We tried Herb medicine to improve the function of Digestive System. The patient's stool condition, subjective sensation related with abdominal pain and general condition improved. 2. We used the Vesiculation therapy using Mylabris which was used traditionally to treat Facial Palsy. We powdered Mylabris and mixed it with Crontonis Fructus to make a paste. We put it on Ye-poong(?風), Nae-gwan(內關) at left side. It induced vesicles at the applied area, but it disappeared in 48 hours without any scar. 3. We applied acupuncture, electroacupunture, massage and self-excercise of face muscles. On gross scale assessment, there was some improvement. And assessment with regional scale also showed changes. The patient and the guardian were satisfied with the result. Conclusion : We experienced a case of Ramsay Hunt syndrome with poor prognosis on EMG. She also showed poor response to conservative treatment. Through various modalities of Oriental medical treatment, we attained some clinical improvement.

• Molecules and Cells
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• v.28 no.6
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• pp.565-573
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• 2009

The pig could be a useful model to characterize molecular aspects determining several delicate phenotypes because they have been bred for those characteristics. The Korean native pig (KNP) is a regional breed in Korea that was characterized by relatively high intramuscular fat content and reddish meat color compared to other western breeds such as Yorkshire (YS). YS grew faster and contained more lean muscle than KNP. We compared the KNP to Yorksire to find molecular clues determining muscle characteristics. The comparison of skeletal gene expression profiles between these two breeds showed molecular differences in muscle. We found 82 differentially expressed genes (DEGs) defined by fold change (more than 1.5 fold difference) and statistical significance (within 5% of false discovery rate). Functional analyses of these DEGs indicated up-regulation of most genes involved in cell cycle arrest, down-regulation of most genes involved in cellular differentiation and its inhibition, down-regulation of most genes encoding component of muscular-structural system, and up-regulation of most genes involved in diverse metabolism in KNP. Especially, DEGs in above-mentioned categories included a large number of genes encoding proteins directly or indirectly involved in p53 pathway. Our results indicated a possible role of p53 to determine muscle characteristics between these two breeds.

• Journal of Preventive Medicine and Public Health
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• v.25 no.4 s.40
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• pp.333-342
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• 1992

The purpose of this study is to estimate the minimum optimal scale(MOS) of the self-employed health insurance associations. Considering the high proportion of operating expenses, the author have selected 254 regional health insurance associations eon the 1990 Finance Report of the self-employed health insurance programs. Both a quadratic function and a hyperbolic function were chosen for the analysis. The dependent variables are the average maintenance cost per insured person and per household, and the independent variables are the number of insured members and of household The minimum optimal scale was obtained from the differentiation of the quadratic function. Major findings are summarized as follows: 1. The M.O.S. was calculated as 166,174 members (27,442 households) for the rural self-employed health insurance associations and 258,462 members (75,446 households) for the urban. Providing that both the rural and urban health insurance associations would be integrated, the M.O.S. be found to become 231,687 members (68,101 households) 2. Compared with the optimal minimum scale, the magnitude of the current health insurance association found to be much smaller, less than half of the optimal scale. 3. In order to reduce the operating cost, it is necessary to enlarge the operational scale of self-employed health insurance associations.

• Animal Systematics, Evolution and Diversity
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• v.28 no.4
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• pp.279-290
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• 2012

Plecoglossus altivelis (ayu) is an amphidromous fish widely distributed in Northeastern Asia from the East China Sea to the northern Japanese coastal waters, encompassing the Korean Peninsula within its range. The shore lines of northeastern region in Asia have severely fluctuated following glaciations in the Quaternary. In the present study, we investigate the population genetic structure and historical demographic change of P. altivelis at a population level in East Asia. Analysis of molecular variance (AMOVA) based on 244 mitochondrial control region DNA sequences clearly showed that as the sampling scope extended to a larger geographic area, genetic differentiation began to become significant, particularly among Northeastern populations. A series of hierarchical AMOVA could detect the genetic relationship of three closely located islands between Korea and Japan that might have been tightly connected by the regional Tsushima current. Neutrality and mismatch distribution analyses revealed a strong signature of a recent population expansion of P. altivelis in East Asia, estimated at 126 to 391 thousand years ago during the late Pleistocene. Therefore it suggests that the present population of P. altivelis traces back to its approximate demographic change long before the last glacial maximum. This contrasts our a priori expectation that the most recent glacial event might have the most crucial effect on the present day demography of marine organisms through bottleneck and subsequent increase of effective population size in this region.