• Journal of Photoscience
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• 제9권2호
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• pp.287-289
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• 2002

Planarians show negative phototaxis and have extensive regenerative ability, including the ability to regenerate the brain. Recently the process of regeneration of the planarian brain has been divided into three steps based on the expression of neural markers. In this study, we have analyzed the process of recovery of the light response during head regeneration. Although morphological observations indicated that regeneration of the eyes and optic nerves appeared to be completed by the fourth day, the recovery of the evasion behavior against light was not recovered within 4 days after amputation. Functional recovery of the evasion behavior could be detected starting 5 days after amputation and then gradually recovered. We previously identified genes which are specifically expressed in the brain after the recovery of morphological structures. This characteristic suggested that these genes may be involved in functional recovery of the brain. To investigate the function of these genes, we performed gene knockout analysis using the RNA interference method. The results clearly indicated that these genes are involved in the functional recovery of the visual system.

• 전력전자학회논문지
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• 제10권4호
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• pp.373-379
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• 2005

본 논문에서는 인버터를 구동하는 용도의 직류전원장치에 대한 제어 알고리즘 개발을 목표로 하고 있으며, 구동과 회생기능을 갖는 전압형 PWM 컨버터에서 운전시 전원의 불평형을 보상하는 제어방법을 제안한다. 교류전원에 대하여 컨버터가 항상 평형상태를 유지하는 방법은 전류제어 루프에 의하여 불평형 상태를 보상하는 방법을 사용하였으며, 불평형의 제어는 전력변환기의 구성면에 있어서 각상의 리액턴스가 같지 않은 누설변압기 등의 사용을 가능하게 하므로 제안된 전력변환기의 하드웨어와 제어 알고리즘은 장치의 소형화와 효율향상에 기여할 것이다.

• 한국산학기술학회논문지
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• 제5권5호
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• pp.413-420
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• 2004

본 연구에서는 인버터를 구동하는 용도의 직류전원장치에 대한 제어 알고리즘 개발을 목표로 하고 있으며, 구동과 회생기능을 갖는 전압형 PWM 컨버터에서 운전시 전원의 불평형을 보상하는 제어방법을 제안하고자 한다. 이를 위해 전력회생기능을 갖는 정류기에 대하여 기존 다이오드 및 SCR을 이용한 정류방식과의 비교를 통해 본 제어방식의 우수성을 시뮬레이션과 실험을 통해 입증하고자 한다. 전력변환기가 항상 평형상태를 유지하기 위해 전류제어 루프에 의하여 불평형 상태를 보상하는 방법을 사용하였으며, 통상적으로 전력변환기의 구성시 각상의 리액턴스가 같지 않은 누설변압기 등의 사용을 가능하게 하므로 제안된 전력변환기의 리액턴스가 불평형상태가 되어도 운전시 항상 평형상태로 유지되어 시스템을 안정적으로 구동 시킬 수 있는 제어기법의 설계를 통해 어떤 환경에서도 장치의 안정된 구동특성을 확인하고자 하였다.

• 한국항공우주학회지
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• 제37권10호
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• pp.1027-1037
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• 2009

우주발사체용 30톤급 액체로켓엔진 재생냉각 연소기 개발과정에 관하여 기술하였다. 이중추진제 동축 와류형 분사기 개발에서부터 시작하여 축소형 연소기를 통해 요소기술을 검증하고 개발된 기술을 실물형 연소기에 적용하였다. 총 5기의 실물형 연소기 개발시제를 사용하여 점화성능, 연소안정성, 연소성능, 냉각성능, 내구성 등의 검증을 수행하였다. 이 과정에서 총 46회의 실물형 연소기 연소시험을 실시하였고 이 중 23회는 기폭장치를 이용한 연소안정성 평가시험을 병행하였다. 시험 결과 30톤급 재생냉각 연소기는 연소 성능 및 연소안정성 요구사항을 모두 만족시켜 단품 개발이 성공적으로 완료된 것으로 평가하였다.

• Clinical Pain
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• 제19권2호
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• pp.80-89
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• 2020

Objective: We compared the regenerative effects of microcurrent therapy (MT) according to the type of electric current, which were direct current microcurrent therapy (DCMT) and alternating current microcurrent therapy (ACMT) on atrophied calf muscle in cast-immobilized rabbit. Method: Rabbits were allocated into control group (sham MT), ACMT group, and DCMT group. Before starting treatment, right gastrocnemius (GCM) muscle was immobilized by cast for 2 weeks. Compound muscle action potential of tibial nerve in nerve conduction study, circumference of calf muscle using a ruler, and thickness of medial and lateral GCM muscle measured by ultrasound, cross sectional area (CSA), and proliferating cell nuclear antigen (PCNA) ratios (%) of muscle fibers were measured on the immunohistochemical analysis. Results: The mean atrophic changes (%) in right medial and lateral GCM muscle thickness, right calf circumference, and amplitude of CMAP of the right tibial nerve in ACMT group and DCMT group were significantly lower than those in control group, respectively (p<0.05). The mean CSA (μm²) of type I and type II and PCNA ratios (%) of medial and lateral GCM muscle fibers in ACMT group and DCMT group were significantly greater than those in control group, respectively (p<0.05). There were no significant differences between the ACMT group and DCMT group at all parameters. Conclusion: This study demonstrated that ACMT and DCMT showed better regeneration effect than sham MT. Microcurrent may be effective in regeneration of atrophied muscle regardless of the type of current.

• Archives of Plastic Surgery
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• 제49권2호
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• pp.266-274
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• 2022

Background Many authors have researched ways to optimize fat grafting by looking for a technique that offers safe and long-term fat survival rate. To date, there is no standardized protocol. We designed a "hydraulic system technique" optimizing the relationship among the quantity of injected fat, operative time, and material cost to establish fat volume cutoffs for a single procedure. Methods Thirty-six patients underwent fat grafting surgery and were organized into three groups according to material used: standard, "1-track," and "2-tracks" systems. The amount of harvested and grafted fat as well as material used for each procedure was collected. Operating times were recorded and statistical analysis was performed to establish the relationship with the amount of treated fat. Results In 15 cases the standard system was used (mean treated fat 72 [30-100] mL, mean cost 4.23 ± 0.27 euros), in 11 cases the "1-track" system (mean treated fat 183.3 [120-280] mL, mean cost 7.63 ± 0.6 euros), and in 10 cases the "2-tracks" one (mean treated fat 311[220-550] mL, mean cost 12.47 ± 1 euros). The mean time difference between the standard system and the "1-track" system is statistically significant starting from three fat syringes (90 mL) in 17.66 versus 6.87 minutes. The difference between the "1-track" system and "2-tracks" system becomes statistically significant from 240 mL of fat in 15 minutes ("1-track") versus 9.3 minutes for the "2-tracks" system. Conclusion Data analysis would indicate the use of the standard system, "1-track," and "2-tracks" to treat an amount of fat < 90 mL of fat, 90 ÷ 240 mL of fat, and ≥ 240 mL of fat, respectively.