• 제목/요약/키워드: Regeneration

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토끼 두개골 결손부에서 블록형과 분말형 hydroxyapatite의 골전도 효과 (The effects of bone regeneration in rabbit calvarial defect with particulated and block type of hydroxyapatite)

  • 구순자;손주연;임현창;엄유정;정의원;김창성;이용근;최성호
    • Journal of Periodontal and Implant Science
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    • 제39권3호
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    • pp.321-329
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    • 2009
  • Purpose: The purpose of this study was to evaluate the bone regeneration of particulated hydroxyapatite(HA) and block type of hydroxyapatite graft in rabbit calvarial defects. Methods: An 8 mm calvarial circular defects were created in sixteen young adult New Zealand white male rabbits (weight $3.0{\sim}3.5kg$). Each defects were filled with Bio-Oss, particulated HA and block type HA. Sham surgery control defects were filled with blood clots. The specimens were harvested at 4 weeks and 8 weeks for histologic and histomorphometric evaluation. Results: Histomorphometric analysis demonstrated statistical differences in defect closure, new bone formation, and bone density of the four groups. Block type of HA group showed increased bone formation and bone density at 4 weeks and 8 weeks compared with Bio-Oss group or sham surgery control group(p<0.05). Conclusions: Block type of HA is an effective material for osteoconduction in rabbit calvarial defects, which may acts as a guide in use of these products in human application.

일본 도시재생사업에서 공공시행자의 역할에 대한 고찰 (A Study on Public Developer's Role through Urban Regeneration Projects in Japan)

  • 조승연;김주진;임정민;류동주
    • 토지주택연구
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    • 제6권4호
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    • pp.177-184
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    • 2015
  • 본 연구는 "도시재생 활성화 및 지원에 관한 특별법(이하 도시재생특별법)"에 의한 도시재생사업에서 공공시행자의 역할을 모색하기 위하여 일본의 도시재생사업을 분석하여 국내에의 시사점을 도출하고자 하는 연구이다. '도시재생법'에서는 공공의 역할이 강조되고 있으나 도시재생활성화계획 수립 이후 사업시행단계에서의 공공의 역할에 대한 언급되지 않고 있어 향후 도시재생사업을 수행함에 있어서 일본 사례를 구체적으로 고찰해보는 것은 중요한 의의가 있는 것으로 판단된다. 구체적으로 일본 도시재생사업에서 공공시행자의 역할을 수행하고 있는 도시재생기구(UR)가 수행한 도쿄의 오오테마치 1-1지구, 시노노메 지구, 시부야역 가구, 오시아게 나리히라바시 4개 지구에 대한 심층 사례분석을 실시하였다. 사업수행체계에서 각 주체가 어떠한 역할을 담당하는지를 고찰해봄으로써 도시재생사업의 성공적인 수행을 위한 공공시행자의 역할을 제시하고자 하였다.

성견의 치조 연상 임플란트주위 결손부에서의 탈회냉동건조골과 e-PTEE막의 효과 (The Effect of Demineralized Freeze - Dried Bone Allograft in Guided Bone Regeneration on Supra - Alveolar Peri - Implant Defects in Dogs)

  • 김창성;최성호;조규성
    • Journal of Periodontal and Implant Science
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    • 제31권1호
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    • pp.57-74
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    • 2001
  • The purpose of this study was to evaluate the adjunctive combined effect of demineralized freeze-dried bone allograft(DFDB) in guided bone regeneration on supra-alveo-lar peri-implant defect. Supra-alveolar perio-implant defects, 3mm in height, each including 4 IMZ titanium plasma-sprayed implants were surgically created in two mongrel dogs. Subsequently, the defects were treated with 1 of the following 3 modalities: Control) no membrane or graft application, Group1) DFDB application, Group2) guided bone regeneration using an expanded polytetra-fluoroethylene membrane, Group3) guided bone regeneration using membrane and DFDB. After a healing period of 12-week, the animals were sacrificed, tissue blocks were harvested and prepared for histological analysis. Histologic examination were as follows; 1. New bon formation was minimal in control and Group 1, but considerable new bone formation was observed in Group 2 and Group 3. 2. There was no osteointegration at the implant-bone interface in the high-polished area of group2 and Group 3. 3. In fluorescent microscopic examination, remodeling of new bone was most active during week 4 and week 8. There was no significant difference in remodeling rate between group 2 and group 3. 4. DFDB particles were observed, invested in a connective tissue matrix. Osteoblast activity in the area was minimal. The results suggest that guided bone regeneration shows promising results in supra-alveolar peri-implant defects during the 12 week healing period although it has a limited potential in promoting alveolar bone regeneration in the high-polished area. There seems to be no significant adjunctive effect when DFDB is combined with GBR.

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치과 진료실에서의 신록 구강 점막 도말 HIV 항체 검사에 한 태도 및 지식에 관한 연구 (Attitudes about rapid Oral HIV screening test in dental clinics)

  • 박정철;김용태;정임희;엄유정;정의원;김창성;조규성;채중규;김종관;최성호
    • 대한치과의사협회지
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    • 제47권5호
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    • pp.291-296
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    • 2009
  • Purpose : The aim of this studγ was to evaluate the patient's and dentist's perspective and knowledge on rapid human immunodeficiency virus screening test in dental setting. Material and Methods: In March 2009, 100 patients and 100 dentists at College of Dentistry, Yonsei University were provided an attitude assessment survey. Results : Results were analyzed for acceptance of testing and potential barriers. 94% of patients agreed to take a rapid HIV screening test and 77% of dentists were willing to provide the test to their patients. Also the current knowledge state of patients and dentists on HIV infection was not accurate as expected. Conclusion : Overall, dental clinic patients widely accepted the offer of rapid oral HIV screening. Rapid HIV screening test in the dental setting ran be an important option to increase the number of individuals who know their HIV status.

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DPF 재생이 경유승용차의 미세입자 배출에 미치는 영향 연구 (Effect of DPF Regeneration on the Nano Particle Emission of Diesel Passenger Vehicle)

  • 권상일;박용희;김종춘;이창식
    • 한국자동차공학회논문집
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    • 제15권3호
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    • pp.153-159
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    • 2007
  • Nano-Particles are influenced on the environmental protection and human health. The relationships between transient vehicle operation and nano-particle emissions are not well-known, especially for diesel passenger vehicles with DPF. In this study, a diesel passenger vehicle was measured on condition of DPF regeneration and no regeneration on a chassis dynamometer test bench. The particulate matter (PM) emission from this vehicle was measured by its number, size and mass measurement. The mass of the total PM was evaluated with the standard gravimetric measurement method while the total number and size concentrations were measured on a NEDC driving cycle using Condensation Particle Counter (CPC) and EEPS. Total number concentration by CPC was $1.5{\times}10^{1l}N/km$, which was 20% of result by EEPS. This means about 80% of total particle emission is consist of volatile and small-sized particles(<22nm). During regeneration, particle emission was $6.2{\times}10^{12}N/km$, was emitted 400 times compared with the emission before regeneration. As for the particle size of $22{\sim}100nm$ was emitted mainly, showing peak value of near 40nm in size. This means regeneration decreased the mean size of particles. Regarding regeneration, PM showed no change while the particle number showed about 6 times difference between before and after regeneration. It seems that the regeneration influences on particle number emissions are related to DPF-fill state and filtration efficiency.

Role of collagen membrane in lateral onlay grafting with bovine hydroxyapatite incorporated with collagen matrix in dogs

  • Jung, Ui-Won;Lee, Jung-Seok;Lee, Geun;Lee, In-Kyeong;Hwang, Ji-Wan;Kim, Min-Soo;Choi, Seong-Ho;Chai, Jung-Kiu
    • Journal of Periodontal and Implant Science
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    • 제43권2호
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    • pp.64-71
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    • 2013
  • Purpose: The objective of this study was to elucidate the role of collagen membranes (CMs) when used in conjunction with bovine hydroxyapatite particles incorporated with collagen matrix (BHC) for lateral onlay grafts in dogs. Methods: The first, second, and third premolars in the right maxilla of mongrel dogs (n=5) were extracted. After 2 months of healing, two BHC blocks ($4mm{\times}4mm{\times}5mm$) were placed on the buccal ridge, one with and one without the coverage by a CM. The animals were sacrificed after 8 weeks for histometric analysis. Results: The collagen network of the membranes remained and served as a barrier. The quantity and quality of bone regeneration were all significantly greater in the membrane group than in the no-membrane group (P<0.05). Conclusions: The use of barrier membranes in lateral onlay grafts leads to superior new bone formation and bone quality compared with bone graft alone.

우리나라 도시재생 계획체계에 대한 연구 : 도시재생전략계획을 대상으로 (A Study on South Korean Urban Regeneration Plan System : for strategic urban regeneration plans)

  • 조병호;류태창;김현
    • 디지털콘텐츠학회 논문지
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    • 제18권8호
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    • pp.1577-1584
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    • 2017
  • 최근 전국적으로 많은 지자체들이 '도시재생특별법' 개정과 '도시재생 선도지역', '도시재생 뉴딜정책'의 추진으로 도시재생 사업을 추진하고 있지만, 공모사업 중심의 도시재생사업은 '도시재생특별법'에 의한 도시재생 계획체계에 맞게 추진하기에는 한계가 있다. 이처럼 공모사업 중심의 획일적인 계획과 비 계획체계에 의한 도시재생사업 추진되고 있어 많은 전략계획과 활성화계획 등 계획수립 소요시간 증가와 이에 따른 사회적 비용증가 등 많은 문제점을 야기하였다. 이에 본 연구에서는 도시재생 계획체계 정립 및 유연화 등의 방법론을 모색하고자 함을 목적으로 도시재생 계획체계의 운영 실태를 분석하여 문제점을 분석하고 개선 방안을 제시하여 우리나라의 도시재생 계획체계 재정립 등의 방안을 연구하고자 한다.

통합형 도시재생사업으로서 마르세유 유로메디테라네의 특성과 시사점 (Characteristics and Implications of Marseille's Euromméditerranée as an Integrated Urban Regeneration Project)

  • 박원석
    • 토지주택연구
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    • 제15권1호
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    • pp.99-115
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    • 2024
  • 본 연구의 목적은 마르세유의 유로메디테라네의 사업 현황과 특성을 살펴보고, 국내 도시재생사업의 활성화를 위한 정책적 시사점을 도출하는 것이다. 연구결과를 요약하면 다음과 같다. 첫째, 유로메디테라네는 마르세유의 도시재생사업으로, 중앙정부와 지방정부가 공동으로 출자・협력한 거버넌스형 사업추진기구인 EPAEM을 통해 사업을 수행하여, 유로메디테라네가 마르세유의 활성화와 삶의 질 개선에 의미 있는 성과를 보임을 확인할 수 있다. 둘째, 도시재생사업으로서 유로메디테라네의 특성으로는 전면 재개발과 수복재개발 방식을 결합한 복합적 접근방법의 활용, 하드웨어적인 물리적 재생과 소프트웨어적인 경제・문화・환경적 재생을 결합한 통합적 재생의 활용, 거버넌스형 도시재생 사업구조의 활용을 들 수 있다. 마지막으로, 국내 도시재생사업의 활성화를 위한 정책적 시사점으로 도시재생사업 단위의 복합화 및 대형화, 국가차원의 거버넌스형 추진기구의 활용, 적절한 민관 파트너십의 활용을 제안하였다.

Periodontal regenerative effect of a bovine hydroxyapatite/collagen block in one-wall intrabony defects in dogs: a histometric analysis

  • Jung, Ui-Won;Lee, Jung-Seok;Park, Weon-Yeong;Cha, Jae-Kook;Hwang, Ji-Wan;Park, Jung-Chul;Kim, Chang-Sung;Cho, Kyoo-Sung;Chai, Jung-Kiu;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
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    • 제41권6호
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    • pp.285-292
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    • 2011
  • Purpose: The aim of this study was to elucidate the effect of a bovine hydroxyapatite/collagen (BHC) block in one-wall intrabony periodontal defects in dogs. Methods: A one-wall intrabony periodontal defect (4 mm wide and 5 mm deep) was prepared bilaterally at the mesial side of the mandibular fourth premolar in five beagle dogs. After thorough root planing, block-type BHC ($4{\times}5{\times}5$ mm) was placed on one side. The contralateral defect area did not receive any material as a sham-surgery control. Histological analysis of the sites was performed after an 8-week healing period. Results: Two of five samples in the experimental group healed well without dissipation of the graft materials, and histological analysis revealed excellent regeneration of the periodontal tissues. However, most of the grafted materials had been displaced in the other three samples, leaving only a small portion of the graft. The measured parameters exhibited large standard deviations, and the mean values did not differ significantly between the experimental and sham-surgery control sides. Conclusions: The application of BHC alone-without a barrier membrane-to wide, one-wall intrabony periodontal defects yielded inconsistent results regarding both periodontal regeneration and substantivity of the graft materials. Thus, the use of a barrier membrane for noncontained-type defects is recommended to improve the stability of the grafted material, and to condense it.