• Title/Summary/Keyword: Reference intervals

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The Apparel Sizing System of the Upper Garments for Early Adolescent Boys (청소년 전기 남학생의 상의 치수 체계에 관한 연구)

  • Kim, Kyung-A;Uh, Mi-Kyung;Suh, Mi-A
    • The Research Journal of the Costume Culture
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    • v.15 no.6
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    • pp.1008-1022
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    • 2007
  • The purpose of this study is to propose apparel sizing system for each body shape of early adolescent boys. The subjects of this study were 549 boys in the capital area. Their body shapes were classified and apparel sizing system was proposed for each body shape. For data analysis were performed descriptive statistics, correlation analysis and crosstabulation using SPSS Ver. 12. The control dimensions to propose apparel sizing system were stature and bust circumference for the upper garments. Intervals between sizes were 5cm for stature and irregular for bust circumference. For each type, $5{\sim}7$ sizes were proposed for upper garments. Reference measurements suggested for upper garments were 9 items. This study is meaningful in that it classified early adolescent boys' body shapes and proposed apparel sizing system for each type of body shape under the current circumstances where basic data for body shape classification and apparel sizing system of early adolescent boys were not in place.

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The Apparel Sizing System of the Lower Garments for Early Adolescent Boys (청소넌 전기 남학생의 하의 치수 체계에 관한 연구)

  • Kim, Kyung-A;Uh, Mi-Kyung;Suh, Mi-A
    • The Research Journal of the Costume Culture
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    • v.16 no.2
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    • pp.278-292
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    • 2008
  • The purpose of this study is to propose apparel sizing system for each body shape of early adolescent boys. The subjects of this study were 549 boys in the capital area. Their body shapes were classified based on 47 anthropometric measurements, 43 photographic measurements and 10 indexed measurements. The apparel sizing system was proposed for each body shape. For data analysis were performed descriptive statistics, correlation analysis and crosstabulation using SPSS Ver. 12. The control dimensions to propose apparel sizing system were stature and waist circumference for the lower garments. Intervals between sizes were 5cm for stature and irregular for waist circumference. For each type, $5{\sim}8$ sizes were proposed for lower garments. Reference measurements suggested fur lower garments were 7 items. This study is meaningful in that it proposed apparel sizing system for each type of body shape. The results of this study are expected to contribute to planning sizes according to the type of body shape and improving the fitness of ready-made clothes in apparel and school uniform manufacturers.

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Bioequivalence Evaluation of Two Brands of Cefixime 100 mg Capsule (Suprax and Alpha-Cefixime) in Korean Healthy Volunteers

  • Choi, Dong-Hyun;Burm, Jin-Pil
    • Biomolecules & Therapeutics
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    • v.15 no.3
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    • pp.182-186
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    • 2007
  • Cefixime is an orally absorbed cephalosporin with a broad spectrum of activity against Gram-negative bacteria and is highly resistant to beta-lactamase degradation. The purpose of the present study was to evaluate the bioequivalence of two cefixime capsules, Suprax capsule (Dong-A Pharmaceutical Co., reference drug) and Alpha-Cefixime capsule (Alpha Pharmaceutical Co., test drug), according to the guidelines of Korea Food and Drug Administration (KFDA). Twenty-four normal subjects, $23.5{\pm}3.72$ years in age and $68.3{\pm}8.89$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. There was one week washout period between the doses. After one capsule containing 100 mg of cefixime was orally administered, plasma was taken at predetermined time intervals and the concentrations of cefixime in plasma were determined using HPLC with UV detector. The pharmacokinetic parameters such as $AUC_{t}$, $C_{max}$ and $T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in $AUC_{t}$, $C_{max}$ and $T_{max}$ between two products were -3.91%, -2.23% and -3.18%, respectively, when calculated against the reference drug. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of $log0.8{\leq}{\delta}{\leq}log1.25$ (e.g., $log0.8786{\leq}{\delta}{\leq}log1.0523$ and $log0.8889{\leq}{\delta}{\leq}log1.0512$ for $AUC_{t}$ and $C_{max}$, respectively). The 90% confidence intervals using untransformed data was within ${\pm}20%$(e.g., $-10.37%{\leq}{\delta}{\leq}6.73%$ for $T_{max}$). All parameters met the criteria of KFDA for bioequivalence, indicating that Alpha-Cefixime capsule (Alpha Pharmaceutical Co.) is bioequivalent to Suprax capsule (Dong-A Pharmaceutical Co.).

Bioequivalence of Dybis Tablet (Metformin Hydrochloride 500 mg) (다이비스 정 (염산메트폴민 500 mg)의 생물학적 동등성)

  • 최준식;박영진;박상묵;범진필
    • YAKHAK HOEJI
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    • v.47 no.4
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    • pp.239-243
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    • 2003
  • Metformin is an oral antihyperglycemic agent used in the therapy of noninsulin-dependent diabetes mellitus and does not cause hypoglycemia at the therapeutic dose. The purpose of the present study was to evaluate the bioequivalence of two metformin hydrochloride tablets, Glucophage tablet (DaeWoong Pharmaceutical Co., reference drug) and Dybis tablet (Shinpoong Pharmaceutical Co., test drug), according to the guidelines of Korea Food and Drug Administration(KFDA). Twenty-four normal volunteers, 26.6$\pm$4.01 years in age and 60.6$\pm$9.80 kg in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After one tablet containing 500 mg of metformin hydrochloride was orally administered, blood was taken at predetermined time intervals and the concentrations of metformin hydrochloride in serum were determined using HPLC with UV detector. The pharmacokinetic parameters such as AUCt, Cmax and Tmax were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in AUCt, Cmax and Tmax between two products were -1.05%, -6.76% and -4.51%, respectively, when calculated against the reference drug. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log0.8$\leq$$\delta$$\leq$log1.25 (e.g., log0.9082$\leq$$\delta$$\leq$log1.0906 and log0.8188$\leq$$\delta$$\leq$log1.0392 for $AUC_{t}$ and $C_{max}$, respectively). The 90% confidence intervals using untransformed data was within $\pm$20% (e.g., -17.66%$\leq$$\delta$$\leq$8.63% for $T_{max}$). All parameters met the criteria of KFDA for bioequivalence, indicating that Dybis tablets (Shinpoong Pharmaceutical Co.) is bioequivalent to Glucophage tablets (DaeWoong Pharmaceutical Co.).

Evaluation of the accuracy of dental casts manufactured with 3D printing technique in the All-on-4 treatment concept

  • Hilin, Tas;Fatih, Demirci;Mesut, Tuzlali;Erkan, Bahce;Guler Yildirim, Avcu
    • The Journal of Advanced Prosthodontics
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    • v.14 no.6
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    • pp.379-387
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    • 2022
  • PURPOSE. The aim of this study is to compare the casts obtained by using conventional techniques and liquid crystal display (LCD) three-dimensional (3D) print techniques in the All-on-4 treatment concept of the edentulous mandibular jaw. MATERIALS AND METHODS. In this study, a completely edentulous mandibular acrylic cast (typodont) with bone-level implants placed with the Allon-4 technique served as a reference cast. In this typodont, impressions were taken with the conventional technique and dental stone casts were obtained. In addition, after scanning the acrylic cast in a dental laboratory scanner and obtaining the Standard Tessellation Language (STL) data, 3D printed casts were manufactured with a 3D printing device based on the design. The stone and 3D printed casts were scanned in the laboratory scanner and STL data were obtained, and then the interimplant distances were measured using Geomagic Control X v2020 (3D Systems, Rock Hill, SC, USA) analysis software (n = 60). The obtained data were statistically evaluated with one-way analysis of variance (ANOVA) and Tukey's pairwise comparison tests. RESULTS. As a result of the one-way ANOVA test, it was determined that the stone casts, 3D printed casts, and reference cast values in all distance intervals conformed to the normal distribution and these values had a significant difference among them in all distance intervals. In Tukey pairwise comparison test, significant differences were found between casts at all distance intervals. In all analyses, the level of significance was determined as .05. CONCLUSION. 3D printed casts obtained with a 3D LCD printing device can be an alternative to stone casts when implants are placed in edentulous jaws. [J Adv Prosthodont 2022;14:379-87]

Scalar First Replacement Strategy for Reference Prediction Table Used in Prefetching Streaming Data (스트리밍 데이터의 선인출에 사용되는 참조예측표의 스칼라 우선 교체 전략)

  • Lim, Chul-hoo;Chon, Young-Suk;Kim, Suk-il;Jeon, Joong-nam
    • The KIPS Transactions:PartA
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    • v.11A no.3
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    • pp.163-172
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    • 2004
  • Multimedia applications tend to access their data as a streaming pattern with regular intervals. This characteristic can be utilized in prefetching the multimedia data into cache memory so as to reduce their execution speeds. The reference-prediction prefetch algorithm predicts the memory address that seems to be used in the next time based on the previous history of memory references stored in the prediction reference table. This paper proposes a strategy to manipulate the reference prediction table which contains all of the data reference instructions to scalar and streaming data. We have recognized that the scalar reference instructions do not contribute to the data prefetching algorithm. Therefore, when replacing an element in the reference prediction table, the proposed algorithm preferentially selects the scalar reference instruction before the stream reference instruction. It makes the stream reference instruction to stay for a long time compared to the FIFO replacement policy, and eventually improves the performance of data prefetching.

Evaluation of Reference Intervals of Some Selected Chemistry Parameters using Bootstrap Technique in Dogs (Bootstrap 기법을 이용한 개의 혈청검사 일부 항목의 참고범위 평가)

  • Kim, Eu-Tteum;Pak, Son-Il
    • Journal of Veterinary Clinics
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    • v.24 no.4
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    • pp.509-513
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    • 2007
  • Parametric and nonparametric coupled with bootstrap simulation technique were used to reevaluate previously defined reference intervals of serum chemistry parameters. A population-based study was performed in 100 clinically healthy dogs that were retrieved from the medical records of Kangwon National University Animal Hospital during 2005-2006. Data were from 52 males and 48 females(1 to 8 years old, 2.2-5.8 kg of body weight). Chemistry parameters examined were blood urea nitrogen(BUN)(mg/dl), cholesterol(mg/dl), calcium(mg/dl), aspartate aminotransferase(AST)(U/L), alanine aminotransferase(ALT)(U/L), alkaline phosphatase(ALP)(U/L), and total protein(g/dl), and were measured by Ektachem DT 60 analyzer(Johnson & Johnson). All but calcium were highly skewed distributions. Outliers were commonly identified particularly in enzyme parameters, ranging 5-9% of the samples and the remaining were only 1-2%. Regardless of distribution type of each analyte, nonparametric methods showed better estimates for use in clinical chemistry compare to parametric methods. The mean and reference intervals estimated by nonparametric bootstrap methods of BUN, cholesterol, calcium, AST, ALT, ALP, and total protein were 14.7(7.0-24.2), 227.3(120.7-480.8), 10.9(8.1-12.5), 25.4(11.8-66.6), 25.5(11.7-68.9), 87.7(31.1-240.8), and 6.8(5.6-8.2), respectively. This study indicates that bootstrap methods could be a useful statistical method to establish population-based reference intervals of serum chemistry parameters, as it is often the case that many laboratory values do not confirm to a normal distribution. In addition, the results emphasize on the confidence intervals of the analytical parameters showing distribution-related variations.

Noninformative Priors for the Coefficient of Variation in Two Inverse Gaussian Distributions

  • Kang, Sang-Gil;Kim, Dal-Ho;Lee, Woo-Dong
    • Communications for Statistical Applications and Methods
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    • v.15 no.3
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    • pp.429-440
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    • 2008
  • In this paper, we develop the noninformative priors when the parameter of interest is the common coefficient of variation in two inverse Gaussian distributions. We want to develop the first and second order probability matching priors. But we prove that the second order probability matching prior does not exist. It turns out that the one-at-a-time and two group reference priors satisfy the first order matching criterion but Jeffreys' prior does not. The Bayesian credible intervals based on the one-at-a-time reference prior meet the frequentist target coverage probabilities much better than that of Jeffreys' prior. Some simulations are given.

A Study on the Suggestion for the Revision of Standard Sizing System for Infant Clothing (유아복의 KS 치수체계 개정을 위한 제안 연구)

  • Jung, Myoung Sook;Suh, Chu Yeon;Lee, Jin Hee
    • Fashion & Textile Research Journal
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    • v.16 no.1
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    • pp.118-127
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    • 2014
  • This study proposed a revision of standard sizing system for infant clothing to provide exact information for consumers and manufacturers. The size designation was set up by compensating the defect of existing system. Basic body measurement and reference body measurement were analysed according to size designation. The ages of the infants ranged from 0 to 36 month in accordance with safety standard of KC Self-Regularity Safety Confirmation. The results are as follows: Size designation for infant clothing was based on height that was basic body measurement. Chest girth, waist girth, head girth, arm length, foot length and weight were also analysed according to age of the month. It was proposed that height could be written alone and height with age of month did together for size designation. Size intervals of basic and reference body measurements were fixed as follows: size intervals are 5 cm in height, 2 cm in chest girth, 2 cm in waist girth, 1 cm in head girth, 2 cm in arm length, 0.5 cm in foot length and 2 kg in weight. The distributions of height and chest girth showed normal distributions. As height was taller, chest girth was also bigger. But the distribution of waist girth didn't show remarkable change with age of month. The distributions of arm length and weight showed remarkable difference with growth in 0~9 months, but the amount of growth variation got less in 12~18 months.

Optimal Monitoring Intervals and MDA Requirements for Routine Individual Monitoring of Occupational Intakes Based on the ICRP OIR

  • Ha, Wi-Ho;Kwon, Tae-Eun;Jin, Young Woo
    • Journal of Radiation Protection and Research
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    • v.45 no.2
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    • pp.88-94
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    • 2020
  • Background: The International Commission on Radiological Protection (ICRP) has recently published report series on the occupational intakes of radionuclides (OIR) for internal dosimetry of radiation workers. In this study, the optimized monitoring program including the monitoring interval and the minimum detectable activity (MDA) of major radionuclides was suggested to perform the routine individual monitoring of internal exposure based on the ICRP OIR. Materials and Methods: The derived recording levels and the critical monitoring quantities were reviewed from international standards or guidelines by the International Atomic Energy Agency (IAEA), the International Organization for Standardization (ISO), and the European Radiation Dosimetry Group (EURADOS). The OIR data viewer provided by ICRP was used to evaluate the monitoring intervals and the MDA, which are derived from the reference bioassay functions and the dose coefficients. Results and Discussion: The optimal monitoring intervals were determined taking account of two requirement conditions on the potential intake underestimation and the MDA values. The MDA requirement values of the selected radionuclides were calculated based on the committed effective dose from 0.1 mSv to 5 mSv. The optimized routine individual monitoring program was suggested including the optimal monitoring intervals and the MDA requirements. The optimal MDA values were evaluated based on the committed effective dose of 0.1 mSv. However, the MDA can be adjusted considering the practical operation of the routine individual monitoring program in the nuclear facilities. Conclusion: The monitoring intervals and the MDA as crucial factors for the routine monitoring were described to suggest the optimized routine individual monitoring program of the occupational intakes. Further study on the alpha/beta-emitting radionuclides as well as short lived gamma-emitting nuclides will be necessary in the future.