• 제목/요약/키워드: Reduction of Weight Bearing

검색결과 94건 처리시간 0.025초

The effects of intra-articular resiniferatoxin on monosodium iodoacetate-induced osteoarthritic pain in rats

  • Kim, Youngkyung;Kim, Eun-hye;Lee, Kyu Sang;Lee, Koeun;Park, Sung Ho;Na, Sook Hyun;Ko, Cheolwoong;Kim, Junesun;Yooon, Young Wook
    • The Korean Journal of Physiology and Pharmacology
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    • 제20권1호
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    • pp.129-136
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    • 2016
  • This study was performed to investigate whether an intra-articular injection of transient receptor potential vanilloid 1 (TRPV1) receptor agonist, resiniferatoxin (RTX) would alleviate behavioral signs of arthritic pain in a rat model of osteoarthritis (OA). We also sought to determine the effect of RTX treatment on calcitonin gene-related peptide (CGRP) expression in the spinal cord. Knee joint inflammation was induced by intra-articular injection of monosodium iodoacetate (MIA, $8mg/50{\mu}l$) and weight bearing percentage on right and left hindpaws during walking, paw withdrawal threshold to mechanical stimulation, and paw withdrawal latency to heat were measured to evaluate pain behavior. Intra-articular administration of RTX (0.03, 0.003 and 0.0003%) at 2 weeks after the induction of knee joint inflammation significantly improved reduction of weight bearing on the ipsilateral hindlimb and increased paw withdrawal sensitivity to mechanical and heat stimuli. The reduction of pain behavior persisted for 3~10 days according to each behavioral test. The MIA-induced increase in CGRP immunoreactivity in the spinal cord was decreased by RTX treatment in a dose-dependent manner. The present study demonstrated that a single intra-articular administration of RTX reduced pain behaviors for a relatively long time in an experimental model of OA and could normalize OA-associated changes in peptide expression in the spinal cord.

전향성 골수내 K-강선을 이용한 중족골 두 및 경부 골절의 비관혈적 정복 및 고정술(6예 보고) (Closed Reduction and Fixation of Metatarsal Head and Neck Fractures Using Antegrade Intramedullary K-wire (6 Cases Report))

  • 김형년;임희준;박용욱
    • 대한족부족관절학회지
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    • 제13권1호
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    • pp.91-94
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    • 2009
  • Metatarsal head and neck fractures are injuries that often result from a direct blow of a heavy objects to the metatarsal head. The head is often impacted or displaced to the plantar aspect that if not treated may cause malunion which later induces painful plantar calluses. If the fracture fragment is large enough, closed reduction may be successfully performed, but when the fragment is small or closed reduction is unsuccessful, open reduction is needed. We present our reduction and fixation technique for the metatarsal head and neck fractures using antegrade intramedullary Kirschner wire (K-wire) without opening the fracture site or infringing the metatarsophalangeal (MTP) joint which allows immediate motion of the joint and partial weight bearing in a stiff soled shoe.

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요부 안정화 운동이 급성기 요통 경감에 미치는 영향 (The Effect of Lumbar Stabilization Exercises on an Acute Lower Back Pain Reduction)

  • 강경화;김동욱;김미정;문현주;박영희;박성덕;김선엽
    • 대한정형도수물리치료학회지
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    • 제10권1호
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    • pp.67-81
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    • 2004
  • The purpose of this study was to investigate between low back pain scale and disability index owing to gait pattern. For the period of February 1 to February 29, 2004, we had conducted a questionnaire and direct interview with 100 persons lived in Daejeon. The result were as follows: 1. The stride length of experimental group, the male was $49.9{\pm}12.9cm$, the female $45.7{\pm}12.9cm$ and the width of feet. the male was $13.5{\pm}5.7cm$, the female $12.2{\pm}4.8cm$. 2. The Fick angle of all subjects was showed in external disposition, the left angle showed in asymmetry, the male was $11.0{\pm}5.7^{\circ}$, the female $8.5{\pm}1.3^{\circ}$. 3. The foot arch was similar to sex as a weight bearing and non-weight bearing, the male was $1.3{\pm}0.8cm$, the female $1.3{\pm}0.9cm$. 4. The impedimental index according to back pain grade, men was a lower than women, the male was $5.7{\pm}6.9$ and the female $7.2{\pm}5.3$. 5. The relation to difference between foot arch and disability index according to back pain grade as a weight bearing and non-weight bearing, the higher foot arch, the higher back pain grade was statistically significance(p<.05). 6. The relation between width of feet and disability index according to back pain grade, the wider width of feet, the higher back pain grade was statistically significance(p<.01). 7. The relation between stride length and disability index according to back pain grade, the wider stride length, the higher back pain grade was statistically significance (p<.05).

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F.R.P 재료 보강에 의한 신개념 중량충격음 저감대책 (Heavy-weight Impact Noise Reduction of Concrete Slab Reinforcement Using F.R.P)

  • 정정호;유승엽;이평직;전진용;조아형
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2005년도 춘계학술대회논문집
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    • pp.383-386
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    • 2005
  • Low frequency heavy-weight impact noise is the most irritating noise in Korean high-rise reinforced concrete apartment buildings. This low frequency noise is generated by foot traffic due to the fact that Koreans do not wear shoes at home. The transmission of the noise is facilitated by a load bearing wall structural system without beams and columns which is used in these buildings. In order to control low frequency heavy-weight impact noise, floating floors using isolation materials such as glass-wool mat and poly-urethane mat are used. However, it was difficult to control low frequency heavy-weight impact sound using isolation material. In this study, reinforcement of concrete slab using beams and plate was conducted. Using the FEM analysis, the effect of concrete slab reinforcement using FRP(fiber-glass reinforced plastic) on the bang machine impact vibration acceleration level and sound were conducted at the standard floor impact sound test building. The $3{\sim}4dB$ floor impact vibration acceleration level and impact sound pressure level were reduced and the natural frequency of slabs were changed.

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자동 닫힘 기능을 갖는 마찰힌지 개발에 관한 연구 (A Study on the Development of Friction Hinge with Automatic Closed Function)

  • 예상돈;민병현
    • 한국기계가공학회지
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    • 제13권1호
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    • pp.107-114
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    • 2014
  • A friction hinge system which moves without power was designed and developed using the principle of friction force, which is caused by interference between the inner diameter of a silicon cap and the outer diameter of a cylindrical roller bearing with one-way rotation in a counterclockwise direction. The system was applied to the lid of buffet ware, which moved up by external force and moved down by gravitational force. However, design conditions which included a rotation angle of the hinge of more than 80 degrees and a closing time of more than 20 seconds were required when the lid of the buffet ware closed due to gravitational force. The design safety of the friction hinge body connected to the lid of the buffet ware from the hinge system was checked on the basis of structural, fatigue and thermal analyses. The material of the shaft, cap and flange among the hinge elements was changed to polyethylene from steel to reduce the weight of the friction hinge system. An injection molding simulation was performed and injection molds of the shaft, cap and flange were created. The weight of the hinge system was decreased from 805g to 219g.

철도차량용 중공차축 설계에 관한 연구 (Study on Design of Railway Hollow Axle)

  • 손승완;정현승;최성규
    • 한국자동차공학회논문집
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    • 제22권4호
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    • pp.46-54
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    • 2014
  • The hollow design of a railway axle is one of the most effective methods to reduce the weight of an axle. However, the conventional hollow axle has the limitation of a lightweight design because it has the same bore diameter along the axial position. The new type of railway axle, the tapered inner surface railway axle, has a different inner diameter between the journal bearing seat and wheel seat. This design method is one way to increase the weight reduction possibility. The purpose of the present study is to establish and evaluate the design of the tapered inner surface railway axle. The case study and Finite Element Method(FEM) are applied to evaluate the strength of the lightweight railway axle according to the European Norm(EN 13103). Finally, the best design case for reducing the weight of the axle is drawn from the results of the case study.

Evaluation of strength properties of cement stabilized sand mixed with EPS beads and fly ash

  • Chenari, Reza Jamshidi;Fatahi, Behzad;Ghorbani, Ali;Alamoti, Mohsen Nasiri
    • Geomechanics and Engineering
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    • 제14권6호
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    • pp.533-544
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    • 2018
  • The importance of using materials cost effectively to enhance the strength and reduce the cost, and weight of earth fill materials in geotechnical engineering led researchers to seek for modifying the soil properties by adding proper additives. Lightweight fill materials made of soil, binder, water, and Expanded polystyrene (EPS) beads are increasingly being used in geotechnical practices. This paper primarily investigates the behavior of sandy soil, modified by EPS particles. Besides, the mechanical properties of blending sand, EPS and the binder material such as fly ash and cement were examined in different mixing ratios using a number of various laboratory studies including the Modified Standard Proctor (MSP) test, the Unconfined Compressive Strength (UCS) test, the California Bearing Ratio (CBR) test and the Direct Shear test (DST). According to the results, an increase of 0.1% of EPS results in a reduction of the density of the mixture for 10%, as well as making the mixture more ductile rather than brittle. Moreover, the compressive strength, CBR value and shear strength parameters of the mixture decreases by an increase of the EPS beads, a trend on the contrary to the increase of cement and fly ash content.

제한적 관혈적 정복술, 금속 핀 고정술 및 일리자로프 외고정 기구를 이용한 리스프랑 관절 골절 및 탈구의 치료 (Treatment of Fracture and Dislocation of Lisfranc joint with Limited Open Reduction, Pin Fixation and Ilizarov External Fixation)

  • 안길영;유연식;윤호현;윤기표;남일현
    • 대한족부족관절학회지
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    • 제8권2호
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    • pp.182-190
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    • 2004
  • Purpose: To evaluate the clinical feature and the results of the treatment of Lisfranc joint fracture/dislocation with limited open reduction, pin fixation and Ilizarov external fixation. Materials and Methods: From June 2001 to May 2003, six patients with Lisfranc fracture/dislocation were treated. The average periods of follow-up was 23 months. After limited open reduction on the second tarso-metatarsal joint, we performed pin fixation of the above joint. On the other Lisfranc joint fracture/dislocation, closed reduction and the application of Ilizarov external fixator was done. This rigid system produced the early partial weight bearing and joint motion of the injured foot and ankle joint. The parameters used were radiographic evaluation, patient's clinical assesment and the AOFAS midfoot score. Results: We used the Myerson's criterier to evaluate the radiographic result. All cases could be achieved more than nearly anatomical reduction. Three cases of excellent and 3 cases of good result could be obtained in the evaluation of the patient's clinical assesment. The average AOFAS midfoot score was 87.2 ($76{\sim}95$) points. Conclusion: The treatment using Ilizarov external fixation on Lisfranc joint fracture/dislocation can be another useful method.

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족근-중족 관절 골절 탈구의 치료경험 (Treatment for Tarsometatarsal Fracture-Dislocation)

  • 정영기;유정한;박용욱;노동근;하성한
    • 대한족부족관절학회지
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    • 제1권2호
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    • pp.112-118
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    • 1997
  • Tarsometatarsal fracture-dislocation is uncommon but severe lesion. Since this lesion is sometimes difficult to recognize by roentgenography, it is easily overlooked. Three patients were treated with open reduction and internal fixation with 3.5 mm cannulated screw and K-wire, two had treatment with open reduction and internal fixation with 3.5 mm cannulated screw only and two had treatment with dosed reduction and short leg cast only between January 1994 and May 1996. The duration of follow-up ranged from twelve to twenty-nine months after the diagnosis. Results were assessed by a subjective questiormaire, physical examination, and radiographic analysis. Multiple fixation techniques for maintaining the reduction of tarsometatarsl joint have been introduced. We recent]y used the 3.5 mm cannulated screw for internal fixation of the tarso-first and second metatarsal fracture-dislocation. We think cannulated screw fixation has several advantages; 1. The cannulated screw fixation is more rigid than the K-wire fixation. 2. There is an decreased risk of screw breakage with early weight bearing. 3. It is possible to compress the involved joints, if necessary. There were no disability in all patients. One patient who was treated with delayed open reduction and internal fixation with 3.5 mm cannulated screw and K-wire had a radiographic mild degenerative arthritis. And one patient who was treated with dosed reduction and short leg cast had a mild metatarsus adductus. But. these two patients were symptom free. There was no correlation between the severity of the diastasis and the patient s functional result.

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족관절 삼과 골절에 대한 치료 후 결과 비교 (Comparison of the Results after the Surgical Treatments of the Trimalleolar Ankle Fractures)

  • 라종득;박현수;임창석;장영수;박상원;정태원;전용수
    • 대한족부족관절학회지
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    • 제8권1호
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    • pp.86-91
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    • 2004
  • Purpose: To evaluate the methods and results of the surgical treatment in the trimalleolar fracture of the ankle. Materials and Methods: We analysed the results of the ankle trimalleolar fracture which were treated with open reduction and internal fixation from January 1999 till September 2003. There were 45 patients who had at least six months follow up, 16 men, and 29 women. We have analysed the mechanism of injury, methods of operation and postoperative complications. Results: The results were assessed on ankle AP, lateral and mortise X-rays and retrospective chart review. There were 30 supination-external rotation, 13 pronation-external rotation, 2 pronation-abduction in the mechanism of injury by Lauge-Hansen classification. Cases of the posterior malleolar fracture which involved more than 25% of the weight bearing surface were 7 (15.6%). Medial malleolar mono-fixation was done in 5 cases, fibular mono-fixation in 2 cases, bimalleolar fixation in 32 cases, trimalleolar fixation in 6 cases. 38 cases (84.4%) were good or excellent in clincal assessment and 39 cases (86.7%) were good or excellent in radiological assessment according to the criteria of the Meyer. There was no difference of results among the surgical treatment methods. Conclusion: The results of our study indicate that the rigid fixation with early ankle motion and weight bearing is needed in ankle trimalleolar fracture. But minimal fixation is not bad in slight displaced fracture. Both anterior approach and posterior approach were useful methods to stabilization the posterior malleolar fracture. And pre-operative evaluation to detect the hidden soft tissue injuries and fracture mechanism is very important to avoid the failure.

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