• Journal of Microbiology and Biotechnology
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• 제11권1호
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• pp.61-64
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• 2001

Delta-integration vectors were constructed for the purpose of achieving homologous integration of the hirudin expression cassette into the chromosome of Saccharomyces cerevisiae. A double $\delta$ system truncated with the unnecessary bacterial genes, and consequently having a reduced insert size for integration, showed a four-fold increase in transformation efficiency at given DNA concentrations, and as a result, the constructed recombinant yeast strain had a 1.3-fold enhancement in hirudin expression level compared with a single $\delta$ system.

• International Journal of Advanced Culture Technology
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• 제8권2호
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• pp.260-269
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• 2020

The Steam Assisted Gravity Drainage (SAGD) process is an enhanced method to extract oil from bitumen which involves surface and central process facilities. This paper describes the Central Process Facilities (CPF) of SAGD and proposes several retrofit plans to the Heat Exchanger Network (HEN). In this approach, the process integration scheme is applied to estimate the energy saving in HENs, and various cases are modeled in favor of a commercial simulator. Throughout this work, a minimum approach temperature of 10℃ is assumed. The results reveal that, due to the HEN optimization using process integration, the heating and cooling duties can be reduced to 29.68MW and 1.886MW, respectively. Compared with the Husky case, all cases considered in this study indicate a potential reduction of at least 6% in total cost, including investment and operation costs.

• 한국정보처리학회논문지
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• 제5권1호
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• pp.103-110
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• 1998

기존의 규칙베이스 추론(Rule-Based REasoning : RBR)과 사례베이스 추론 (Case-Base : CB)가 통합되어 추론되고 있지만, 많은 수의 규칙(Rule)과 사례(Case)에 의해 추론 시간이 많이 걸리는 단점이 있다. 본 논문에서는 이런 단점을 해결하기 위하여, 다중 의미 또는 불확실한 지식을 쉽게 표현할 수 있는 라프집합 (Rough Set)을 이용하여 RB와 CB를 간략화한 새로운 추론 방법을 제안한다. 라프집합의 식별(classification)과 근사(aprroximation)개념을 이용하여, RB와 CB를 통치 클래스(equivalence class)로 분류하여 각각을 각략화하고, 간략화된 RB와 CB를 이용하여 통합 추론하여, 상호 보완적인 역할에 의해 결정 해를 얻고자 하는 것이다.

• 한국해양공학회지
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• 제6권2호
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• pp.46-54
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• 1992

In this paper, behavior of rectangular storage structures under earthquake loadings are investigated. Linear sloshing is assumed in this study. The effect of the wall flexibility is considered. Eulerian and lagrangian approaches are presented. The Eulerian approach is carried out by solving the boundary value problem for the fluid motion. In the lagrangian approach, the fluid as well as the storage structure is modelled by the finite element method. The fluid region is discretized by using fluid elements. The (1 $\times$ 1)-reduced integration is carried out for constructing the stiffness matrices of the fluid elements. Seismic analysis of the coupled system is carried out by the response spectra method. The numerical results show that the fluid forces on the wall obtained by two approaches are in good agreements. By including the effect of the wall flexibility, the forces due to fluid motion can be increased very significantly.

• 한국자동차공학회논문집
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• 제5권3호
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• pp.220-228
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• 1997

We discuss finite element approximation and use a Mindlin plate element based upon uniformly reduced numerical integration. The finite element selected for use in this work is a four-node, bilinear displacement element based upon the Mindlin theory of plates. Such elements show good accuracy for laminated composite plates when reduced numerical integration is used to evaluate the element marices. This study presents both the experimental and F.E. results for the natural frequencies of CFRPURETHANE-CFRP Composite plate. Good agreement between experimental and calculated frequencies is achived.

• 전산구조공학
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• 제10권2호
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• pp.139-148
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• 1997

A finite element method is programmed to analyse the nonlinear behavior of axisymmetric structures. The lst order Mindlin shell theory which takes into account the transversal shear deformation is used to formulate a conical two node element with six degrees of freedom. To evade the shear locking phenomenon which arises in Mindlin type element when the effect of shear deformation tends to zero, the reduced integration of one point Gauss Quadrature at the center of element is employed. This method is the Updated Lagrangian formulation which refers the variables to the state of the most recent iteration. The solution is searched by Newton-Raphson iteration method. The tangent matrix of this method is obtained by a finite difference method by perturbating the degrees of freedom with small values. For the moment this program is limited to the analyses of non-linear elastic problems. For structures which could have elastic stability problem, the calculation is controled by displacement.

• Steel and Composite Structures
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• 제47권3호
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• pp.365-374
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• 2023

This paper presents a new scheme for constructing locking-free finite elements in thick and thin plates, called Discrete Shear Gap element (DSG), using multiphase material topology optimization for triangular elements of Reissner-Mindlin plates. Besides, common methods are also presented in this article, such as quadrilateral element (Q4) and reduced integration method. Moreover, when the plate gets too thin, the transverse shear-locking problem arises. To avoid that phenomenon, the stabilized discrete shear gap technique is utilized in the DSG3 system stiffness matrix formulation. The accuracy and efficiency of DSG are demonstrated by the numerical examples, and many superior properties are presented, such as being a strong competitor to the common kind of Q4 elements in the static topology optimization and its computed results are confirmed against those derived from the three-node triangular element, and other existing solutions.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
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• pp.75-80
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• 2004

By the SOG (System-on-Glass) technology with excimer laser anneal process, the number of IC chips and the area of the mounted IC chips on the printed circuit board are reduced. In new circuit integrations on the glass substrate, we have developed D/A converter including the new capacitor array, amplifier comprising the original comparators and new display device with capturing images by integrated sensor into a pixel. This paper discusses the application of circuit integration of low-temperature poly-Si.

• 한국분무공학회지
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• 제18권3호
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• pp.132-139
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• 2013

Smoke emissions from light duty diesel vehicles were measured using light extinction method with the free acceleration test mode. The smoke emissions for each measurement cycle of the free acceleration method showed large variations according to driver's pedal pushing pattern. The smoke values for each measurement cycle initially increased and reach a peak value. Integration of the smoke emissions with time for each measurement cycle was performed to get a representative smoke value which was obtained by averaging the integrated results. Two kinds of integration time range were used. One is range over the whole measurement cycle of the free acceleration method. The other is only the acceleration range in the measurement cycle. Overall, variation of the representative smoke values obtained by the integration method was reduced comparing to the traditional representative smoke value which was obtained from a peak smoke value over the measurement cycle. Ten vehicles of the same model with 2.5 liter diesel engines, and seven vehicles of the same model with 2.7 liter diesel engines, were tested using the free acceleration test method.

• 한국건설관리학회논문집
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• 제18권3호
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• pp.42-51
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• 2017

건설 프로젝트의 생산과정에서 성과를 지속적으로 측정하고 평가하는 것은 프로젝트관리의 성공적인 수행을 위한 핵심요소이다. 성과는 일반적으로 목적물에 할당 된 공정과 원가 관련 정보를 정량적으로 평가함으로써 측정되며, 객관적인 성과측정을 위해 공정과 원가가 통합적으로 계획 관리되어야 한다. 본 연구는 공정과 원가의 통합 모델을 통해 성과 측정 방법론을 제안하고 진도관리의 기반을 마련하는데 목적이 있다. 이를 위해 공정계획과 원가계획의 표준화된 업무 프로세스를 개발하였고, EVM과 기존의 통합 모델을 분석하여, 성과측정 유닛을 활용한 WBS와 CBS의 통합 방법론을 제시하였다. 플랜트 프로젝트의 시공단계를 중심으로 공통 성과측정의 대상은 공종으로 선정하여 성과측정 유닛을 규정하고 공정과 비용정보를 연계시켜 성과비율을 산정하였다. 또한 리소스의 적용시 원가요소 중 소모성자원의 비용을 배제하여 진도측정의 객관성을 향상하였다. 본 결과는 실제 플랜트 사례 프로젝트에 적용하여 실증되었으며, 개발된 방법론은 향후 프로젝트의 성과를 보다 객관적인 기준으로 평가할 수 있어 보다 효과적인 진도관리 방법이 될 것으로 판단된다.