• Journal of Korean Tunnelling and Underground Space Association
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• v.2 no.2
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• pp.32-40
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• 2000

This paper presents the results of a parametric study on the behavior of tunnel face reinforced with horizontal pipes. A series of reduced-scale model tests was carried out to in an attempt to verify previously performed three-dimensional numerical modeling and to investigate effects of reinforcement layout on the tunnel face deformation behavior. The results of model tests indicate that the tunnel face deformation can significantly reduced by pre-reinforcing the tunnel face with longitudinal members and thus enhancing the tunnel stability. In addition, the model tests results compare fairly well with those from the previously performed three-dimensional finite element analysis. Therefore, a properly calibrated three dimensional model may effectively be used in the study of tunnel face reinforcing technique.

• Asian-Australasian Journal of Animal Sciences
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• v.14 no.2
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• pp.268-275
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• 2001

The effects of homogenization conditions and $\beta$-cyclodextrin ($\beta$-CD) on cholesterol removal of Mozzarella cheese were examined. The homogenization pressure influenced markedly on the cholesterol removal in milk and, 75.64% of cholesterol, the highest rate, was removed at $70.0kg/cm^2$. In addition, an increase in temperature resulted in an increase of cholesterol removal in the range of 71.75 to 78.22%. Among different concentrations of $\beta$-CD addition, 1.0% showed 78.21% of cholesterol removal. Therefore, cholesterol-reduced Mozzarella cheese was made by cheese milk treated with 70 $70.0kg/cm^2$ homogenization at $70^{\circ}C$ and 1% $\beta$-CD addition for a subsequent study. The cholesterol reduction of cholesterol-reduced Mozzarella cheese was 63.92%. Meltability, stretchability and oiling-off in cholesterol-reduced cheese were significantly lower than those in control. Hardness, gumminess and chewiness were significantly reduced, while cohesiveness and elasticity increased. Appearance and flavor of the cheese were superior, but texture inferior to the control.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2003-2007
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• 2012

Purpose: E-cadherin is a transmemberane protein which is responsible for adhesion of endothelial cells. The aim of our study was to assess existing evidence of associations between reduced expression of E-cadherin and prognosis of ovarian cancer with a discussion of potential approaches to exploiting any prognostic value for improved clinical management. Methods: We conducted a meta-analysis of 9 studies (n=915 patients) focusing on the correlation of reduced expression of E-cadherin with overall survival. Data were synthesized with random or fixed effect hazard ratios. Results: The studies were categorized by author/year, number of patients, FIGO stage, histology, cutoff value for E-cadherin positivity, and methods of hazard rations (HR) estimation, HR and its 95% confidence interval (CI). Combined hazard ratios suggested that reduced expression of E-cadherin positivity was associated with poor overall survival (OS), HR= 2.10, 95% CI:1.13-3.06. Conclusion: The overall survival of the E-cadherin negative group with ovarian cancer was significant poorer than the E-cadherin positive group. Upregulation of E-cadherin is an attractive therapeutic approach that could exert significant effects on clinical outcome of ovarian cancer.

• The Journal of Korean Medicine
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• v.25 no.1
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• pp.117-128
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• 2004

Objectives : This research was performed to investigate effect of Samul-tang-gamibang against focal cerebral ischemic damage after middle cerebral artery occlusion(MCAO). Methods : This research was used rats which were against focal cerebral ischemic damage by MCAO. It was used Zea Longa's theory and Belayev's methods to give rise to focal cerebral ischemic damage by MCAO. After 7days later, we drew out the brain and then had frozen and dyeing it and we had taken a picture to measure of the damaged area in each brain section. We determined the Neurological Index and tested the Foot-fault test and Roatated test to appraise the fall of motion ability result from cerebral ischemic damage. Results : The results of the experiment are as follows. 1. Samul-tang-gamibang reduced infarct size of sample group compared to control group at 7 day after MCAO. 2. Samul-tang-gamibang reduced infarct volume of sample group compared to control group at 7 day after MCAO. 3. Samul-tang-gamibang reduced foot-fault index of sample group compared to control group at 5,7 day after MCAO. Conclusions : Samul-tang-gamibang has protective effects against ischemic brain damage and had significant reduced infarct size and infarct volume of Rt-MCAO.

• BMB Reports
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• v.29 no.4
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• pp.365-371
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• 1996

Partially reduced interferon-a ($IFN-{\alpha}$) was cross-linked with thymosin ${\alpha}1$ ($T{\alpha}1$) using sulfo-succinimidyl (4-iodoacetyl) amino benzoate (SIAB), a bifunctional cross-linking reagent. The partially reduced $IFN-{\alpha}$ optimal for the cross-linking reaction was obtained by incubating native $IFN-{\alpha}$ with 0.5 mM DTT at $30^{\circ}C$ for 60~100 min. $T{\alpha}1$ was activated by incubating with sulfo-SIAB at $37^{\circ}C$ for 30 min to produce $T{\alpha}1-IAB$. The $T{\alpha}1-IFN-{\alpha}$ cross-linking was achieved by the reaction of the partially reduced $IFN-{\alpha}$ with $T{\alpha}1-IAB$. This cross-linking was between the sulfhydryl group of Cys1 in $IFN-{\alpha}$ and the N-terminal amino group of $T{\alpha}1$ through acetyl amino benzoate as a spacer. The immunological activity of the cross-linked molecule showed the same extent as that of $T{\alpha}1$, and most of the antiviral activity was retained compared to that of the partially reduced $IFN-{\alpha}$.

• Journal of information and communication convergence engineering
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• v.14 no.4
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• pp.246-251
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• 2016

In this study, we developed a reduced 94 GHz hybrid ring coupler on a GaAs substrate in order to demonstrate the possibility of the integration of various passive components and MMICs in the millimeter-wave range. To reduce the size of the hybrid ring coupler, we used multiple open stubs on the inside of the ring structure. The chip size of the reduced hybrid ring coupler with multiple open stubs was decreased by 62% compared with the area of the hybrid ring coupler without open stubs. Performance in terms of the loss, isolation, and phase difference characteristics exhibited no significant change after the use of the multiple open stubs on the inside of the ring structure. The reduced hybrid ring coupler showed excellent coupling loss of $3.87{\pm}0.33dB$ and transmission loss of $3.77{\pm}0.72dB$ in the measured frequency range of 90-100 GHz. The isolation and reflection were -48 dB and -32 dB at 94 GHz, respectively. The phase differences between two output ports were $180^{\circ}{\pm}1^{\circ}$ at 94 GHz.

• International Journal of Fluid Machinery and Systems
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• v.7 no.3
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• pp.110-124
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• 2014

Surge phenomena in the zone of reduced speeds in a system of a nine-stage axial flow compressor coupled with ducts were studied analytically by use of a surge transient simulation code. Main results are as follows. (1) Expansion of apparently stable, non-surge working area of the pressure vs. flow field beyond the initial stage-stall line was predicted by the code in the lower speed region. The area proved analytically to be caused by significantly mismatched stage-working conditions, particularly with the front stages deep in the rotating stall branch of the characteristics, as was already known in situ and in steady-state calculations also. (2) Surge frequencies were found to increase for decreasing compressor speeds as far as the particular compressor system was concerned. (3) The tendency was found to be explained by a newly introduced volume-modified reduced surge frequency. It suggests that the surge frequency is related intimately with the process of emptying and filling of air into the delivery volume. (4) The upstream range of movement of the fluid mass having once passed through the compressor in surge was found to reduce toward the lower speeds, which could have caused additionally the increase in surge frequency. (5) The concept of the volume-modified reduced surge frequency was able to explain, though qualitatively at present, the behaviors of the area-pressure ratio parameter for the stall stagnation boundary proposed earlier by the author.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.6C
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• pp.602-608
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• 2003

In this paper, we propose an efficient DCT calculation method for fast video encoding. We show that the SAD obtained in the motion estimation and compensation process is decomposed into the positive and negative terms. Based on a theoretical analysis, it is shown that the DCT calculation is classified into 4 cases - DCT Skip, Reduced_DCT1 , Reduced_DCT2, and original DCT- according to the positive and negative terms. In the proposed algorithm, one of 4 cases is used for DCT in order to reduce the computational complexity. The simulation results show that the proposed algorithm achieves computational saving approximately 25.2% without image degradation and computational overhead.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.05a
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• pp.633-638
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• 2002

The vacuum cleaner that has no dust bag generates very high level annoying noise. The dominant noise source is the 2$\^$nd/ BPF tone of the rotating impeller. In order to reduce the noise, we identify the acoustic characteristics and reduce the noise of the vacuum cleaner and centrifugal fan. The resonance phenomenon is observed in blade passages and we found out that the resonance frequency is very close to the 2$\^$nd/ BPF. In order to reduce this high-level peak noise, new impeller is designed in this paper. The trailing edge of new impeller is inclined and this makes the flow interactions between the rotating impeller and the stationary diffuser vane occurs with some phase shift. The performance of new impeller is similar to the old one but the overall SPL is reduced about 3.6dBA. The SPL of BPF is reduced about 6dBA and 2$\^$nd/ BPF is reduced about 20dBA. The vacuum cleaner, which uses newly developed centrifugal fan, generate more comfortable noise than the old model and the strong tonal sound was dramatically reduced.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.23 no.4
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• pp.301-327
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• 2019

The proper orthogonal decomposition (POD) method for time-dependent problems significantly reduces the computational time as it reduces the original problem to the lower dimensional space. Even a higher degree of reduction can be reached if the solution is smooth in space and time. However, if the solution is discontinuous and the discontinuity is parameterized e.g. with time, the POD approximations are not accurate in the reduced space due to the lack of ability to represent the discontinuous solution as a finite linear combination of smooth bases. In this paper, we propose to post-process the sample solutions and re-initialize the POD approximations to deal with discontinuous solutions and provide accurate approximations while the computational time is reduced. For the post-processing, we use the Gegenbauer reconstruction method. Then we regularize the Gegenbauer reconstruction for the construction of POD bases. With the constructed POD bases, we solve the given PDE in the reduced space. For the POD approximation, we re-initialize the POD solution so that the post-processed sample solution is used as the initial condition at each sampling time. As a proof-of-concept, we solve both one-dimensional linear and nonlinear hyperbolic problems. The numerical results show that the proposed method is efficient and accurate.