• Title/Summary/Keyword: Red blood

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A microscopic study on the rheological properties of human blood in low concentration limit

  • Kang, In-Seok
    • Korea-Australia Rheology Journal
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    • v.14 no.2
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    • pp.77-86
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    • 2002
  • A microscopic theoretical study is performed to predict the rheological properties of human blood in the low concentration limit. The shear thinning behavior of blood in the low shear limit is studied by considering the aggregate formation of red blood cells, which is called the rouleaux formation. Then the constitutive equations of blood in the high shear limit are derived for various flow situations by considering the unique features of deformation of blood cells. Specifically, the effects of the surface-area-preserving constraint and the lank-treading motion of blood cells on the rheological properties are studied.

Case of the Anti-Type 2 Diabetes Effects on the Prescription of Red Onion (한약과 자색양파 제재로 호전된 제2형 당뇨병 42례 보고)

  • Lee, Jeong Won;Kim, Yi Soon;Kim, Chang Tae;Kwak, Yi Sub;Lee, Hai Woong;Han, Cho Ryang;Oh, Mi Jung;Kim, Gyeong Cheol
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.27 no.4
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    • pp.465-470
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    • 2013
  • The purpose of this study is to observe clinically the effects of red onion prescription on type 2 diabetes. The subject of this study were middle-aged people. We measured clinically physiological index, body composition, radial arterial pulse wave before taking medicine and after taking medicine for 4 month (the prescription of red onion). The study results were as follows. In physiological Index, diastolic blood pressure(mmHg)(p<0.001), Fasting blood glucose(mg/dL)(p=0.001), and HbA1c(%)(p<0.001) were decreased significantly after taking medicine. In body Composition, waist-hip ratio(p=0.031), body fat percentage(p=0.006), fat mass(kg)(p=0.005), and muscle mass(kg)(p=0.001) were decreased significantly after taking medicine. Blood Circulation Index, ECO(L/min)(p=0.038) and ECI($L/min/m^2$)(p=0.007) were increased significantly after taking medicine, ECR($dyne^*sec^*cm^{-5}$)(p=0.002), and ECRI($dyne^*sec/cm$)(p=0.001) were decreased significantly after taking medicine for 4 month. The prescription of red onion was showed significant change in physiological index, character of body composition, blood circulation index. Based on this result, it is considered that red onion prescription has the positive effects on type 2 diabetes and blood circulation clinically. In the future, diversified studies on the effects of red onion prescription are needed.

Effects of Crude Saponin and Saponin-free Fraction of Korea Red Ginseng on the Skin and Cerebral Blood Flow in the Rats (백서의 피부 및 뇌혈류에 미치는 고려홍삼 사포닌 및 비사포닌의 영향)

  • Kim, Shin-Hee;Kim, Cuk-Seong;Park, Jin-Bong;Han, Chan-Soo;Kim, Kwang-Jin;Kim, Shin-Hye;Kim, Se-Hoon;Nam, Ki-Yeul;Jeon, Byeong-Hwa
    • Journal of Ginseng Research
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    • v.26 no.3
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    • pp.132-138
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    • 2002
  • To study the effect of Korea red ginseng (KCG) on the skin and cerebral blood flow, we evaluated the change of skin perfusion rate and cerebral perfusion rate after the intravenous, intraperitoneal, and oral administration of crude saponin (CS) and saponin-free fraction (SFF) of KRG in the rats. The change of skin perfusion rate and cerebral perfusion rate was measured laser doppler flowmetry. The intravenous injections of CS or SFF of KRG and intraperitoneal injection of SFF of KRG did not change the relative skin and cerebral blood flow in the rats. When the rats were treated by the intraperitoneal injection of CS of KRG, relative cerebral blood flow was significantly increased with a time-dependent manner, however, relative skin blood flow was not influenced by the them. Oral administration of CS of KRG slightly increased skin blood flow in the rats. Also, the change of cerebral blood flow by transient bilateral carotid arterial clamp in the CS-treated rats was significantly decreased, compared with control groups. From the above results, it was suggested that Korea red ginseng have a increasing property of cerebral blood flow in the rats.

Relation between Various Body Fluid Volumes and Body Weight or Lean Body Mass in the Rats (흰쥐의 체액량과 체중 및 무지방 체중 사이의 관계)

  • Ahn, Hyung-Che;Nam, Kee-Yong
    • The Korean Journal of Physiology
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    • v.3 no.1
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    • pp.1-9
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    • 1969
  • Relationships between red ceil volume $(^{51}Cr-cell)$, total blood volume (red cell volume divided by hematocrit ratio), and extracellular fluid volume (SCN distribution space) and body weight (ranging between 73 and 384 grams) or lean body mass were studied in 59 nembutalized rats. Lean body mass was determined by means of underwater weighing method on rats clipped and eviscerated. There were positive correlations between body weight or lean body mass and the absolute values (in milliliters) of body fluid volumes. Body fluid volumes expressed on the body weight or lean body mass basis, however, showed negative correlations between body weight (grams) or lean body weight (grams) with one exception. Red cell volume expressed as % lean body mass showed a positive correlation with lean body mass. The other results are summarized as follows: 1. Body density of rats was 1.0561 $(range:\;1.0123{\sim}1.0781)$ and 19.8% body weight of total body fat was obtained. The mean value of lean body mass was 80.2% body weight 2. The correlation between body weight and lean body mass was high, namely, coefficient of correlation was r=.99. 3. The correlation between the absolute value of red cell volume (ml) and body weight showed a high correlation, namely, r= 92 and between the lean body mass coefficient of correlation was r=.93. On a weight basis, red cell volume was 2.67 ml/100 gm body weight or 3.48 ml/100 gm lean body mass. The coefficient of correlation between body weight (grams) and red cell volume (% body weight) was r=-. 30. The coefficient of correlation between lean body mass (grams) and red cell volume (% lean body mass) was r=. 50. Thus, the following regression equation was obtained. Red cell volume (% lean body mass)=. 00243 Lean body mass (gm)+3. 12. 4. Total blood volume was 6.06% body weight or 7.83% lean body mass. The correlation between these blood volume values and body weight or lean body mass were negative, namely, r= -.43 and r=-.42 respectively. 5. Extracellular volume (SCN space) was 30.0% body weight or 37.2% lean body mass. These percentage values showed negative correlations between body weight or lean body mass and coefficients of correlation were r=-.40 and r=-.54 respectively. 6. The rate of increase in body weight or lean body mass is accompanied by a smaller rate of increase in blood volume and extracellular fluid volume. The rate of increase in red ceil volume paralled that of lean body mass.

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Genetic studies of blood markers in Cheju horses I. Red blood cell types (제주마의 혈액형에 관한 연구 I. 적혈구 항원형)

  • Cho, Gil-jae;Kim, Taek-soo;Um, Young-ho;Kim, Bong-hwan;You, Jai-sun
    • Korean Journal of Veterinary Research
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    • v.39 no.6
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    • pp.1066-1072
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    • 1999
  • The present study was carried out to investigate the blood markers of Cheju horses. The red cell types (blood groups) were tested from 73 Cheju native horses and 118 Cheju racehorses by serological procedures with 23 reagents. The blood group phenotypes observed with high frequency were Pb(34.3%), Qc(56.2%), Qb(15.1%) and genotypes Dbcm/dghm(12.3%), Dde/dghm(9.6%), Dad/bcm(6.8%), Dcgm/de(6.8%) in Cheju native horses, while Aa(63.6%), Pa(44.9%), P-(28.8%), Qabc(36.4%), Dbcm/cgm(14.4%), Dbcm/bcm(10.2%), Dbcm/de(7.6%), Dbcm/dghm(5.1%), Dde/dk(5.1%) in Cheju racehorses. Alleles observed with high frequency were Ab(0.128), Ac(0.169), Dad(0.103), Dadn(0.075), Ddghm(0.226), Pb(0.316), Qc(0.494) in Cheju native horses and Aa(0.529), Dbcm(0.306), P-(0.531), Qabc(0.197), Q-(0.504) in Cheju racehorses. No specific variation of blood groups and allele frequencies of C,K,U system were observed in Cheju native horses and Cheju racehorses. The mean heterozygosity in Cheju native horses and Cheju racehorses was observed 0.5344 and 0.5102, respectively.

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Repressive effects of red bean, Phaseolus angularis, extracts on obesity of mouse induced with high-fat diet via downregulation of adipocyte differentiation and modulating lipid metabolism

  • Park, Young Mi;Kim, Jee In;Seo, Dong Hyun;Seo, Joo Hee;Lim, Jae-Hwan;Lee, Jong Eun;Choi, Je-Yong;Seo, Eul-Won
    • Food Science and Biotechnology
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    • v.27 no.6
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    • pp.1811-1821
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    • 2018
  • Obesity is generally caused by quantitative changes in adipocyte differentiation and fat metabolism. Only a few studies have been determined the effect of red beans extract on obesity and plasma cholesterol concentration. We have been studied the functional activities of red-bean extracts including anti-oxidative effect against DNA and cell damages. Histological study including micro CT analysis showed that the accumulation of fat in hepatocytes and intestines was significantly decreased in red bean extract treated group. In addition, plasma cholesterol and triglyceride levels were decreased in blood samples. In addition, it was confirmed that the red bean extract inhibited the expression of $PPAR{\gamma}$, Fabp4 and RETN genes, which regulate total adipocyte differentiation and lipid metabolism. Red bean extract inhibits the expressions of transcription factors associated with adipocyte differentiation in a dose-dependent manner, thereby inhibiting fat accumulation and decreasing blood lipid levels in obese mice induced by high fat diet.

Trypanosomiasis in a calf (송아지 트리파노조마증)

  • 김종택;위성환
    • Journal of Veterinary Clinics
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    • v.15 no.1
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    • pp.193-195
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    • 1998
  • A one-month old Holstein calf with clinical histories of diarrheal weekness and behavioural abnormality revealed clinical findings of anemia and dehydration. The red blood cells were $1.4{\times} 10^{6}/{\mu}l$ and packed red cell volume was 45%. A blood smear showed a large number of circulating Trypanosoma theileri. To treat Trypanosomiasisi the patient received once a daily oral dosage o$\ulcorner$ 10 mg/kg of the Quinidine sulfate including transfusion (200 ml) for 3 days. After 2 weeks, the calf recovered body condition. These results suggest that Administration of Quinidine sulfate in trypanosomiasis may be a useful treatment approach.

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Effects of Fermented Red Ginseng Supplementation on Growth Performance, Apparent Nutrient Digestibility, Blood Hematology and Meat Quality in Finishing Pigs

  • Ao, X.;Meng, Q.W.;Kim, I.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.4
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    • pp.525-531
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    • 2011
  • This study was conducted to evaluate the effects of fermented red ginseng (FRG) on growth performance, apparent nutrient digestibility, blood hematology and meat quality in finishing pigs. A total of 96 ((Landrace${\times}$Yorkshire)${\times}$Duroc) pigs ($71.64{\pm}1.20\;kg$) were randomly allocated into one of the following dietary treatments: i) CON, basal diet; ii) FRG1, basal diet+1 g/kg fermented red ginseng; iii) FRG2, basal diet+2 g/kg fermented red ginseng and iv) FRG3 basal diet+4 g/kg fermented red ginseng. There were 6 replications per treatment with 4 pigs (2 gilts and 2 barrows) per pen. Throughout the whole period of the trial, there were no effects of FRG addition on ADG or G/F. Pigs fed FRG2 diet had lower ADFI (p<0.05) than those fed CON diet during 0-4 weeks while FRG2 and FRG3 treatments decreased ADFI (p<0.05) compared with CON treatment both during 5-8 weeks and the entire experiment. No differences were observed in apparent nutrient digestibility and blood hematology. However, FRG2 and FRG3 administration decreased the drip loss compared with CON (p<0.05). Pigs in FRG2 treatment had higher LMA (p<0.05) and lower WHC (p<0.05) than those in CON treatment. In conclusion, the supplementation of FRG had a minor effect on performance while partially improved meat quality in finishing pigs.

Analysis of conventional drag and lift models for multiphase CFD modeling of blood flow

  • Yilmaz, Fuat;Gundogdu, Mehmet Yasar
    • Korea-Australia Rheology Journal
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    • v.21 no.3
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    • pp.161-173
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    • 2009
  • This study analyzes especially drag and lift models recently developed for fluid-solid, fluid-fluid or liquid-liquid two-phase flows to understand their applicability on the computational fluid dynamics, CFD modeling of pulsatile blood flow. Virtual mass effect and the effect of red blood cells, RBCs aggregation on CFD modeling of blood flow are also shortly reviewed to recognize future tendencies in this field. Recent studies on two-phase flows are found as very useful to develop more powerful drag-lift models that reflect the effects of blood cell's shape, deformation, concentration, and aggregation.