• Title/Summary/Keyword: Red Lead

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Short-Term Viral Evolution in Response to Passaging I. Consequences for Population Size

  • Park, Gyung-Soon;Steven E. Kelley;Hing, Jung-Lim
    • 한국생태학회:학술대회논문집
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    • 2002.08a
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    • pp.83-91
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    • 2002
  • The Red Queen hypothesis for the advantage of sex predicts that pathogens will evolve by increasing fitness with frequent encounters with specific host genotypes. In this study, BMV population size, measured as an indicator of fitness, was investigated during repeated passages through the same, or different host genotypes of the crop host, Hordeum vulgare (barley). Overall, mean BMV concentration within individual hosts was significantly higher in genetically homogeneous compared to heterogeneous host passage lines. In addition, BMV populations, passaged through a specific host variety, showed higher growth in that host variety compared to BMV passaged through varying varieties. These results supports the Red Queen hypothesis. However, the decrease in viral populations during passages contradicts the Red Queen. Nevertheless, the results found here show that even under simplified conditions, pathogens do not evolve in simple, predictable ways. Constraints on pathogen evolution may lead to counterintuitive results.

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Successful Birth of Pups Produced by GnRH-induced Estrus and Natural Mating in Captive Red Fox (Vulpes vulpes)

  • Yong, Hwan-Yul;Bae, Bok-Soo;Kim, Seung-Dong;Lim, Yang-Mook;Ha, Yong-Hee;Oh, Chang-Sik;Kim, Myoung-Ho;Jo, Sin-Il;Yoo, Mi-Hyun;Jeong, Yu-Jeong;Ro, Sang-Chul
    • Journal of Embryo Transfer
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    • v.25 no.4
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    • pp.287-290
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    • 2010
  • On January 6, 2010, two months earlier than normal breeding season, a red fox vixen was implanted with synthetic GnRH analogue, Deslorelin. Blood was sampled every 2~3 days from the day of implant to identifying spermatozoa on stains of epithelial cells. Estradiol and progesterone were examined. Even though the vixen was in non-breeding season, she was mated by a male fox. Pregnancy was confirmed by canine pregnancy detection kit that detect relaxin released from placenta. Four healthy pups were born on March 9, 2010. This is the first report showing synthetic GnRH can activate ovarian function and lead to fertile estrus of red fox in non-breeding season.

Short-Term Viral Evolution in Response to Passaging I. Consequences for Population Size

  • Park, Gyung-Soon;Kelley, Steven E.;Hong, Jung-Lim
    • The Korean Journal of Ecology
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    • v.25 no.4
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    • pp.217-225
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    • 2002
  • The Red Queen hypothesis for the advantage of sex predicts that pathogens will evolve by increasing fitness with frequent encounters with specific host genotypes. In this study, BMV population size, measured as an indicator of fitness, was investigated during repeated passages through the same, or different host genotypes of the crop host, Hordeum vulgare (barley). Overall, mean BMV concentration within individual hosts was significantly higher in genetically homogeneous compared to heterogeneous host passage lines. In addition, BMV populations, passaged through a specific host variety, showed higher growth in that host variety compared to BMV passaged through varying varieties. These results supports the Red Queen hypothesis. However, the decrease in viral populations during passages contradicts the Red Queen. Nevertheless, the results found here show that even under simplified conditions, pathogens do not evolve in simple, predictable ways. Constraints on pathogen evolution may lead to counterintuitive results.

The Influence of Ascorbic Acid and Methionine on the $\delta$-Aminolevulinic Acid Dehydratase Activity in Lead Poisoning. (납중독에 있어서 $\delta$-Aminolevulinic Acid Dehydratase 활성에 미치는 Ascorbic Acid 및 Methionine의 효과에 관한 연구)

  • 윤혜정
    • YAKHAK HOEJI
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    • v.19 no.1
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    • pp.21-29
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    • 1975
  • The activity of $\delta$-aminolevlinic acid dehydratase (ALAD) in red cell of rabbit inhibited by addition of $Pb(Ac)_{2}$(50mg/kg) to rabbit caused to diminish completely the ALAD activity in blood within shr. Pretreatment of ascorbic acid and methionine decreased the increment of $\delta$-aminolevulinic acid output in urine by lead poisoning.

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The Experimental Study on Performance of Cementitious and Organic Anti-corrossion Coatings (시멘트계 및 유기계 도포재료의 방청성능에 관한 실험적 연구)

  • 신도철;이종열;박정순;오희갑;이태규
    • Proceedings of the Korea Concrete Institute Conference
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    • 1995.10a
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    • pp.150-154
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    • 1995
  • The purpose of this study is to evalute the mechanical and the anti-corrosion characteristics of cementitious, organic coatings on steel plates. Tests are performed according to KS M 5331, 5250, etc'. For the test, we used water based epoxy, Tar epoxy, the red lead, and cementitious anti-corrosion coatings. The results of adhension tests satisfying the requirements in relevant standards The impact test shown that the impact test shown that the impact resistance of cementitious anti-corrosion test, rred lead, epoxy, cementitiouse show good corrosion resistance.

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The Effect of Ginseng Petroleum Ether Fraction on Immunosuppressed Mice by Lead acetate (I) I. Humoral Immune Response and Biochemical Studies (납의 면역독성에 미치는 인삼의 영향(I) I. 체액성면역 및 생화학적 검사)

  • 김휘배;안영근;김주영;김정훈
    • Environmental Analysis Health and Toxicology
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    • v.1 no.1
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    • pp.27-36
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    • 1986
  • Experiments were performed on mice to investigate the effect of Panax ginseng petroleum ether fraction on the immunotoxicity of lead acetate. Lead acetate was administered in the drinking water and ginseng p-ether fraction was injected intraperitoneally, Mice were sensitized and challenged with sheep red blood cell. Humoral immune responses were evaluated by antibody production and Arthus reaction. Pathotoxicological influences were measured by serum protein, alkaline phosphatase and total cholesterol. The weight of liver, spleen and thymus were measured. Lead acetate exposure significantly decreased hemagglutination titer, hemolysin titer, Arthus reaction, spleen and thymus weight. Ginseng p-ether fraction administration significantly restored or potentiated reduced humoral immune response, spleen and thymus weight. Reduced serum A/G ratio, total cholesterol and alkaline phosphatase activity were restored or increased by ginseng p-ether fraction administration.

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Studies on the Bis (amino-alkyl-oxo) Oxalate Derivatives As a Antidote of Lead poisoning (Bis (\beta$-amino-alkyl-oxo) oxalate 유도체의 납 중독 해독에 관한 연구)

  • 최선아;유미례;노영수;정성현;정세영
    • Environmental Analysis Health and Toxicology
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    • v.4 no.3_4
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    • pp.1-6
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    • 1989
  • The effects of his ($\beta$-amino-ethyl-oxo) oxalate and bis ($\alpha$-amino-methyl-oxo) oxalate on the toxicity of lead acetate in rast were examined. Rats were given intraperitoneally at the dose of lead acetate 45 mg/kg. The exposure of lead acetate showed the 70% decrease of ALAD ($\delta$-amino levulinic acid dehydratase) activity in red blood cell. In vivo 122 mg/kg administration of bis ($\beta$-amino-ethyl-oxo) oxalate and bis ($\alpha$-amino-methyl-oxo) oxalate showed the 50% increase of ALAD activity, whereas 149 mg/kg administeration of Ca-EDTA had no effect. In vitro, the same results were obtained. Both compounds had hemolytic activity at concentrations higher than that required for showing the 50% ALAD activity increase in vivo.

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Interpretation of Coloring Technique and Pigment Analysis for King Sejo's Palanquin in Gongju Magoksa Temple, Korea (공주 마곡사 세조대왕연의 안료분석 및 채색기법 해석)

  • Kim, Ji Sun;Lee, Chan Hee
    • Journal of Conservation Science
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    • v.35 no.5
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    • pp.403-415
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    • 2019
  • According to oral tradition, the King Sejo's palanquin is indeed the palanquin of King Sejo, the 7th monarch of the Joseon dynasty who reigned from 1455 to 1468, which was left behind after visiting the Magoksa temple. The palanquin is painted in five colors, mainly black, white, yellow, red and green. The chromaticity measurement of the yellow pigment showed that orpiment and gold are a noticeable distinction between the lightness and b values. In the case of the red pigment, a values of areas painted with cinnabar tend to measure at high values. As a result of the optical microscopy, scanning electron microscopy and energy dispersive spectroscopy analyses, it was determined that Chinese ink was used for the black pigment, lead white and white clay were used for the white, and orpiment and gold for the yellow. The red pigment was found to be the result of minium, cinnabar and red ocher, atacamite was used as green pigment. Though the analysis results of the cross sections on very small exfoliation fragments of pigments, it was confirmed that white clay and lead white were used for the preparation layer. In addition, several coloration techniques were considered based on these analyses.

Composition Classification of Korea Ancient Glasses by Using Raman Spectroscopy (라만분광분석법을 이용한 한국 고대 유리의 조성 분류)

  • Sim, Woo Seok;Kim, Eun A;Lim, Soo Yeong;Kim, Hyung Min;Kim, Gyu Ho
    • Journal of Conservation Science
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    • v.38 no.2
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    • pp.117-123
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    • 2022
  • In this study, investigated the possibility of quantitatively and qualitatively analyzing Korean ancient glasses via Raman Spectroscopy. We subjected four categories of Korean traditional glasses, namely, lead-BaO, lead, potash, and soda glasses (3, 3, 10, and 10 pieces, respectively), to this analytical technique. The results showed significant differences between the stretching and bending Raman vibration regions corresponding to these different Korean ancient glass types. Specifically, the stretching vibration regions corresponding to lead-BaO and lead glasses showed peaks at 1040 and 1000 cm-1, respectively; the stretching vibration region of normal glass appears at 1100 cm-1. The bending vibration regions corresponding to potash and soda glass showed Raman peaks at 490 and 560 cm-1, respectively. Furthermore, the Raman spectra of the lead and lead-BaO glasses showed red shifts, which depended on the amount of PbO present. Thus, our findings highlighted the possibility of quantitatively determining the amount of PbO, a major component of lead glasses, via Raman Spectroscopy.

Development of an Agar Diffusion Method to Measure Elastase Inhibition Activity Using Elastin-Congo Red

  • Jung Kyung-Hwan;Kim Hyun-Joo
    • Journal of Microbiology and Biotechnology
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    • v.16 no.8
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    • pp.1320-1324
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    • 2006
  • The pancreatic and neutrophil elastases are associated with several illnesses including lung and vascular diseases, various cancers, and pancreatitis. The development of a potent and specific inhibitor to the elastases could lead to new therapies. In this study, an agar diffusion method was modified to include a substrate-dye conjugate (Elastin-Congo red) as a substrate of elastase and an indicator of elastase inhibitory activity. The Elastin-Congo red agar plates consisted of 0.1 % Elastin-Congo red and 2.5% agar. The elastase and elastase inhibitors were simultaneously loaded into wells, ultimately resulting in halo formations in which the halo diameter decreased as the concentration of elastase inhibitor increased. The concentration of elastase inhibitor in the samples, therefore, was inversely proportional to the halo diameters. This simplified method provided an excellent correlation with the standard microplate technique, which uses a chromogenic substrate. The concentration of elastase inhibitor obtained from the culture supernatant of a recombinant elastase inhibitor produced by the yeast Pichia pastoris was easily determined. This study has established a simple modified and inexpensive agar diffusion method that is potentially useful for the identification, quantification, and screening of new elastase inhibitors.