• Tuberculosis and Respiratory Diseases
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• 제77권6호
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• pp.274-278
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• 2014

Antiphospholipid syndrome (APS) is an acquired systemic autoimmune disorder characterized by a combination of clinical criteria, including vascular thrombosis or pregnancy morbidity and elevated antiphospholipid antibody titers. It is one of the causes of deep vein thrombosis and pulmonary embolism that can be critical due to the mortality risk. Overall recurrence of thromboembolism is very low with adequate anticoagulation prophylaxis. The most effective treatment to prevent recurrent thrombosis is long-term anticoagulation. We report on a 17-year-old male with APS, who manifested blue toe syndrome, deep vein thrombosis, pulmonary thromboembolism, and cerebral infarction despite adequate long-term anticoagulation therapy.

• Tuberculosis and Respiratory Diseases
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• 제41권2호
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• pp.152-157
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• 1994

본 저자들은 양측성으로 반복되는 자연기흉 소견을 보인 21세 남자 환자에서BAL은 시행하여 조직구내 Birbeck granule을 찾음으로써 확진할 수 있었던 골 침범을 동반한 폐 조직구증 1예를 문헌 고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제35권4호
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• pp.315-317
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• 2002

방선균증이 폐를 침범하여 수술을 시행하는 경우는 매우 드물며 본 저자들은 반복적인 객혈을 주소로 내원한 남자 환자에서 폐결핵 의심하에 폐절제 수술을 하였으며 병리소견상 폐 방선균증으로 진단되었기에 보고한다. 환자는 49세 남자로 내원 전 임상증상과 단순 흉부 촬영에서 폐결핵으로 진단 후 결핵약을 복용 중이었으나 지속적인 결핵약 복용에도 증상의 호전이 없고 단순 흉부 촬영 및 흉부 컴퓨터 촬영 상 좌폐 상엽에 동공 형성을 보여 결핵약에 반응을 보이지 않는 폐결핵으로 의심하고 외과적 절제술을 시행하였다. 외과적 절제술 후 병리조직학적 검사 상 sulfur granule을 확인하여 방선균증을 진단하였다. 환자는 수술 후 문제없이 퇴원하여 6개월간 항생제 치료를 받을 예정이다.

• Tuberculosis and Respiratory Diseases
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• 제38권4호
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• pp.389-395
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• 1991

Pulmonary hemorrhage is a feature of several immune and idiopathic disorders. The specific etiology of this disease is determined by clinical, serological and renal pathology. Microscopic polyarteritis nodosa is a vasculitis of small vessels which is characterized by involvement of the lung, kidney and skin in young individuals. Its clinical manifestations differ from classical polyarteritis nodosa. It should be considered in differentiation of recurrent alveolar hemorrhage and hematuria. We reported a case of microscopic polyarteritis nodosa which was confirmed by renal biopsy and positive serum antineutrophil cytoplasmic antibody, associated with recurrent alveolar hemorrhage and hematuria.

• Tuberculosis and Respiratory Diseases
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• 제52권6호
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• pp.651-656
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• 2002

Hyperimmunoglobulin E 증후군, 혹은 Job's 증후군은 비정상적으로 높은 Immunoglobulin E 수치와 더불어 면역기능의 이상으로 인해 반복적인 피부감염과 호흡기계 감염을 특정으로 하는 질환이다. Job's 증후군에서 나타나는 호흡기계 발현 양상은 폐렴, 기류, 기흉, 폐농양, 농흉 등 여러 가지 형태로 나타나며 각각에 대한 치료도 다양하다. 치료원칙은 감염에 관한 예방적 약물치료 및 감염균에 관한 항생제투여와 수술의 적응증이 될 때, 폐실질의 손실을 최소화하는 폐절제술을 시행하는 것이 중요하다.

• Tuberculosis and Respiratory Diseases
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• 제39권6호
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• pp.548-553
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• 1992

저자들은 최근 시작된 수차례의 객혈을 주소로 본원에 입원한 39세 남자 환자에서 좌측 폐동맥 형성부전증으로 확진하였기에 문헌 고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제25권7호
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• pp.711-715
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• 1992

Massive hemoptysis is defined as pulmonary hemorrhage of more than 600ml to 800ml within 24hours. Among the many causes, the most common include pulmonary tuberculosis, abscess, bronchiectasis, cystic fibrosis bronchial carcinoma. Most acute episodes of hemoptysis last less than 24 hours and gradually subside. However, when the hem-optysis is massive, it carries a mortality rate of 50% to 100%. It is generally agreed that surgery is the treatment of choice for patients with massive hemoptysis. We had the one case of 39 year-old male with recurrent massive hemoptysis. In the past history, he had pulmonary tuberculosis 20 years ago but no chest trauma, Previous chest CT showed well defined cavitary lesion with calcification on RUL Under the bronchoscope finding, we indentified active bleeding from right upper lobe bronchus without end-obronchial lesion. Therefore, emergency thoracotomy was done with impression of hem-optysis due to pulmonary tuberculosis. But operative findings were as follows ; the 4th fractured rib was impacted into the lung parenchyme with severe adhesion and middle lobe was not inflated. So, Upper and middle lobectomy were performed. He was diagnosed finally by operative and pathological findings as massive hemoptysis due to impaction of fractured rib into the lung parenchyme and discharged without complication.

• Tuberculosis and Respiratory Diseases
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• 제39권1호
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• pp.95-101
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• 1992

저자들은 최근 심한 늑막액이 반복되는 환자에서 재발성 일측성 폐정맥 폐쇄증을 진단후 추적관찰하였기에 문헌고찰과 함께 보고하였다.

• Journal of Chest Surgery
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• 제28권11호
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• pp.1058-1062
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• 1995

We have experienced one case of hemoptysis which developed from both upper lung fields due to pulmonary aspergilloma combined with pulmonary tuberculosis. A 48 year old female patient was admitted with 10 years history of recurrent hemoptysis. Chest X-ray film revealed moderately advanced active pulmonary tuberculosis lesion on both upper lung fields, and cresentic radiolucent space between cavity wall and round radiopaque lesion on left upper lung field. Bronchial arteriogram showed hypervascularity and extravasation of contrast media in the right lung and it was treated by bronchial artery embolization. Hemoptysis recurred 7 months after embolization and repeat examination revealed greatly increased bronchial vasculature in the left upper lobe and therefore underwent left upper lobectomy. The pathologic result was compatible with aspergillosis, and the postoperative recovery was uneventful.

• Tuberculosis and Respiratory Diseases
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• 제77권4호
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• pp.172-177
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• 2014

Background: Pseudomonas aeruginosa infection is particularly associated with progressive and ultimately chronic recurrent respiratory infections in chronic obstructive pulmonary disease, bronchiectasis, chronic destroyed lung disease, and cystic fibrosis. Its treatment is also very complex because of drug resistance and recurrence. Methods: Forty eight cultures from 18 patients with recurrent P. aeruginosa pneumonia from 1998 to 2002 were included in this study. Two or more pairs of sputum cultures were performed during 2 or more different periods of recurrences. The comparison of strains was made according to the phenotypic patterns of antibiotic resistance and chromosomal fingerprinting by pulsed field gel electrophoresis (PFGE) using the genomic DNA of P. aeruginosa from the sputum culture. Results: Phenotypic patterns of antibiotic resistance of P. aeruginosa were not correlated with their prior antibiotic exposition. Fifteen of 18 patients (83.3%) had recurrent P. aeruginosa pneumonia caused by the strains with same PFGE pattern. Conclusion: These data suggest that the most of the recurrent P. aeruginosa infections in chronic lung disease occurred due to the relapse of prior infections. Further investigations should be performed for assessing the molecular mechanisms of the persistent colonization and for determining how to eradicate clonal persistence of P. aeruginosa.