• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.5
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• pp.25-36
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• 2016

The goal of the SmartGrid is to maximize energy efficiency by exchanging bi-directional real-time power information with the help of ICT(Information and Communication Technology). In this paper, we propose a "JRS-MS" (Joint Routing and Scheduling for Multi-channel SmartGrid) algorithm that uses numerical modeling methods in IEEE 802.11s based STDMA multi-channel SmartGrid NAN networks. The proposed algorithm controls the amount of data transmission adaptively at the link layer and finds a high data-rate path which has the least interference between traffic flows in multi-channel SmartGrid NAN networks. The proposed algorithm improve transmission performance by enhancing network utilization. By comparing the results of performance analysis between the proposed algorithm and the JRS-SG algorithm in the previous paper, we showed that the JRS-MS algorithm can improve transmission performance by maximally utilizing given network resources when the number of flows are increasing in the multi-hop NAN wireless mesh networks.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.7 no.4
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• pp.36-48
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• 2008

Variable Message Signs(VMS) is one of the important subsystems of Intelligent Transportation Systems (ITS), which is useful for providing drivers with real-time information on traffic, roadway or weather conditions. In order to maximize the effectiveness of the VMS system, it is required to reflect drivers's preference on designing and operating the system. In this context, this study was conducted to develop strategies to deliver the messages in an efficient manner while many other previous studies focused primarily on the contents of the messages, from drivers's perspectives. Drivers's preference on message expression formats and message display orders were investigated through image analysis in the perspectives of a total of 40 subjects. With respect to message expression formats, drivers preferred Gulim or Dodum in font style, middle arrangement of the letters, pictogram combination as opposed to letters only, blank time less than 0.5 sec, appearing message in animation effect, messages in single phase, non-flashing message. In the matter of message display orders, drivers preferred to obtain link or traffic information in the lust place. Then, they desired to be informed of roadway condition and instructions or recommendations for drivers to cope with unexpected events among various messages for traffic condition.

• Journal of Ginseng Research
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• v.39 no.3
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• pp.230-237
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• 2015

Background: Colorectal cancer (CRC) is a leading cause of death worldwide. Chronic gut inflammation is recognized as a risk factor for tumor development, including CRC. American ginseng is a very commonly used ginseng species in the West. Methods: A genetically engineered $Apc^{Min/+}$ mouse model was used in this study. We analyzed the saponin composition of American ginseng used in this project, and evaluated its effects on the progression of high-fat-diet-enhanced CRC carcinogenesis. Results: After oral ginseng administration (10-20 mg/kg/d for up to 32 wk), experimental data showed that, compared with the untreated mice, ginseng very significantly reduced tumor initiation and progression in both the small intestine (including the proximal end, middle end, and distal end) and the colon (all p < 0.01). This tumor number reduction was more obvious in those mice treated with a low dose of ginseng. The tumor multiplicity data were supported by body weight changes and gut tissue histology examinations. In addition, quantitative real-time polymerase chain reaction analysis showed that compared with the untreated group, ginseng very significantly reduced the gene expression of inflammatory cytokines, including interleukin-$1{\alpha}$ (IL-$1{\alpha}$), IL-$1{\beta}$, IL-6, tumor necrosis factor-${\alpha}$, granulocyte-colony stimulating factor, and granulocyte-macrophage colony-stimulating factor in both the small intestine and the colon (all p < 0.01). Conclusion: Further studies are needed to link our observed effects to the actions of the gut microbiome in converting the parent ginsenosides to bioactive ginseng metabolites. Our data suggest that American ginseng may have potential value in CRC chemoprevention.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.15 no.1
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• pp.28-38
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• 2016

Cooperative-Intelligent Transport Systems (c-ITS) has emphasized a real-time traffic safety service in urgent situations among highway infrastructure and four-wheeled vehicles, while two-wheeled vehicles, e.g. bicycles and motorcycle, sharing highway space and endangering highway safety, have yet been out of its interest. This paper delivers the results of a study conducted to analyze the patterns of two-wheeled-vehicle traffic accidents experienced in the past, the last three years (2011~2013), and to propose the types of service enhancing the safety of the riders of those. It was found from the analysis of historical accident data that the side collision on a link section should be taken care of for further safety treatment, while the old female drivers need additional care to decrease their fatality rate. By combining the services proposed for bicycles and motorcycles, this paper proposes (1) eight different bicycle-to-everything (B2X) services which can be eventually provided in c-ITS and (2) three of those that would be available in the near future with the current communication technologies.

• KIPS Transactions on Computer and Communication Systems
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• v.5 no.10
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• pp.311-318
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• 2016

IoT(Internet of Things areas) rich information based on the user easy access to service creation must be one of the power system of specificity due following: The IoT spread obstacle to the act be, and 'Smart Grid information of this is not easy under power plants approach the Directive on the protection measures, particularly when stringent security policies IoT technologies applied to Advanced Metering Infrastructure sector has been desired. This is a situation that occurs is limited to the application and use of IoT technologies in the power system. Power Information Network is whilst closed network operating is has a smart grid infrastructure, smart grid in an open two-way communication for review and although information security vulnerabilities increased risk of accidents increases as according to comprehensive security policies and technologies are required and can. In this paper, the IoT platform architecture design of information systems as part of the power of research and development IoT-based energy information platform aims. And to establish a standard framework for a connection to one 'Sensor-Gateway-Network-platform sensors Service' to provide power based on the IoT services and solutions. Framework is divided into "sensor-gateway" platform to link information modeling and gateways that can accommodate the interlocking standards and handling protocols variety of sensors Based on this real-time data collection, analysis and delivery platform that performs the role of the relevant and to secure technology.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.11
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• pp.367-373
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• 2017

The O2O service is an efficient way to operate based on systematic connection of the offline and online states. At present, education, health checkups, and exposure management of radiation workers are separated from offline and online at nuclear-related workplaces. Therefore, we developed a radiation workers management program at the workplace and tried to link online and offline states. After applying the program to the local network, we developed a written employee management system as a computer program and applied it to radiation workers and radiation safety managers at a university hospital in Daejeon using a questionnaire. As a result of the survey, the results of this program can enhance the awareness of safety management and work convenience. There is also a demand for radiation closed workers as well as radiation relative workers. It will be necessary to collect opinions regarding the characteristics of each workplace for the generalization of the radiation workers management program. As a result, real-time radiation safety management and work improvement can be expected through network connections between the workplace, supervisory authority, and related organizations in the future. If a circle structure is formed using the employee management program, development of radiation safety management can be expected.

• Journal of KIISE:Information Networking
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• v.36 no.6
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• pp.492-504
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• 2009

The delivery of multimedia that efficiently adapts its bit-rate to changing network characteristics and conditions is one of the important challenging tasks in the design of today's real-time multimedia streaming systems such as IPTV, Mobile IPTV and so on. In these work, the primary focus is on network congestion, to improve network stability and inter-protocol fairness. However, these existing works have problems which do not support QoE (Quality of Experience), because they did not consider essential characteristics of contents playback such as the media continuity. In this paper, we propose a novel rate control scheme for improving the QoE of multimedia streaming service in the Internet congestion, called NCAR (Network and Client-Aware Rate control), which is based on network-aware congestion control and client-aware flow control scheme. Network-aware congestion control of the NCAR offers an improving reliability and fairness of multimedia streaming, and reduces the rate oscillation as well as keeping high link utilization. Client-aware flow control of NCAR offers a removing the media discontinuity and a suitable receiver buffer allocation, and provides a good combination of low playback delay. Simulation results demonstrate the effectiveness of our proposed schemes.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8579-8587
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• 2016

Background: The molecular mechanisms linking breast cancer progression and inflammation still remain obscure. The aim of the present study was to investigate the possible association of angiopoeitin like protein 4 (ANGPTL4) and its regulatory factor, hypoxia inducible factor-$1{\alpha}$ (HIF-$1{\alpha}$), with the inflammatory markers nuclear factor kappa B/p65 (NF-${\kappa}B$/P65) and interleukin-1 beta (IL-$1{\beta}$) in order to evaluate their role in inflammation associated breast cancer progression. Materials and Methods: Angiopoietin-like protein 4 (ANGPTL4) mRNA expressions were evaluated using quantitative real time PCR and its protein expression by immunohistochemistry. DNA binding activity of NF-${\kappa}B$/P65 was evaluated by transcription factor binding immunoassay. Serum levels of ANGPTL4, HIF-$1{\alpha}$ and IL-$1{\beta}$ were immunoassayed. Tumor clinico-pathological features were investigated. Results: ANGPTL4 mRNA expressions and serum levels were significantly higher in high grade breast carcinoma ($1.47{\pm}0.31$ and $184.98{\pm}18.18$, respectively) compared to low grade carcinoma ($1.21{\pm}0.32$ and $171.76{\pm}7.58$, respectively) and controls ($0.70{\pm}0.02$ and $65.34{\pm}6.41$, respectively), (p<0.05). Also, ANGPTL4 high/moderate protein expression was positively correlated with tumor clinico-pathological features. In addition, serum levels of HIF-$1{\alpha}$ and IL-$1{\beta}$ as well as NF-${\kappa}B$/P65 DNA binding activity were significantly higher in high grade breast carcinoma ($148.54{\pm}14.20$, $0.79{\pm}0.03$ and $247.13{\pm}44.35$ respectively) than their values in low grade carcinoma ( $139.14{\pm}5.83$, $0.34{\pm}0.02$ and $184.23{\pm}37.75$, respectively) and controls ($33.95{\pm}3.11$, $0.11{\pm}0.02$ and $7.83{\pm}0.92$, respectively), (p<0.001). Conclusion: ANGPTL4 high serum levels and tissue expressions in advanced grade breast cancer, in addition to its positive correlation with tumor clinico-pathological features and HIF-$1{\alpha}$ could highlight its role as one of the signaling factors involved in breast cancer progression. Moreover, novel correlations were found between ANGPTL4 and the inflammatory markers, IL-$1{\beta}$ and NF-${\kappa}B$/p65, in breast cancer, which may emphasize the utility of these markers as potential tools for understanding interactions for axes of carcinogenesis and inflammation contributed for cancer progression. It is thus hoped that the findings reported here would assist in the development of new breast cancer management strategies that would promote patients' quality of life and ultimately improve clinical outcomes. However, large-scale studies are needed to verify these results.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.10
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• pp.4353-4358
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• 2014

Background: PI3/AKT and NF-kB signaling pathways are constitutively active in acute myeloid leukemia and cross-talk between the two has been shown in various cancers. However, their role in acute myeloid leukemia has not been completely explored. We therefore used cell penetrating inhibitor peptides to define the contributions of AKT and NF-kB to survival and multi drug resistance (MDR) in HL-60 cells. Materials and Methods: Inhibition of AKT and NF-kB activity by AKT inhibitor peptide and NBD inhibitor peptide, respectively, resulted in decreased expression of mRNA for the MDR1 gene as assessed by real time PCR. In addition, treatment of HL-60 cells with AKT and NBD inhibitor peptides led to inhibition of cell viability and induction of apoptosis in a dose dependent manner as detected by flow cytometer. Results: Finally, co-treatment of HL-60 cells with sub-optimal doses of AKT and NBD inhibitor peptides led to synergistic apoptotic responses in AML cells. Conclusions: These data support a strong biological link between NF-kB and PI3-kinase/AKT pathways in the modulation of antiapoptotic and multi drug resistant effects in AML cells. Synergistic targeting of these pathways using NF-kB and PI3-kinase/AK inhibitor peptides may have a therapeutic potential for AML and possibly other malignancies with constitutive activation of these pathways.

• The Journal of the Korea Contents Association
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• v.11 no.1
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• pp.34-41
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• 2011

At present wireless internet access service is available through the 3G network, mobile WiMAX and WiFi anytime and anywhere. In this environment where there are various networks, users should be able to select specific networks depending on different situations. And it is necessary to provide mobility support between homogeneous and between heterogenous networks. Given this situation, the many proposals have been presented to link 3G, which has the largest service area among various networks, with mobile WiMAX(IEEE 802.16e), or with WiFi(IEEE 802.11). But, recently, with the increasing volume of wireless internet use and wireless internet data, due to the advents of net-book, e-book and smart phone, the service area of WiFi and mobile WiMAX has rapidly expanded. Especially, the availability of real-time application such as internet phone has led to the relative shrinking of the proportion of 3G mobile communication network giving conventional voice service, and enlargement of those of wireless internet access networks like WiFi and mobile WiMAX. This paper suggests a handover scheme based on PMIPv6, whitch support mobility between WiFi and mobile WiMAX, and minimizes handover delay. In this scheme, the mobile node has a dual stack structure composed of two interfaces-WiFi and mobile WiMAX. Since WiFi dose not support mobility, it is suggested that the mobile node have the capacity to deal with handover signaling between gateway in case of handover between homogeneous networks. This handover scheme, suggested comparing with current handovers between homogeneous networks, has proved, in its analytic evaluation, to be able to reduce handover, transmission, and signaling overhead.