• Applied Microscopy
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• v.51
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• pp.12.1-12.12
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• 2021

Intravital video microscopy permits the observation of microcirculatory blood flow. This often requires fluorescent probes to visualize structures and dynamic processes that cannot be observed with conventional bright-field microscopy. Conventional light microscopes do not allow for simultaneous bright-field and fluorescent imaging. Moreover, in conventional microscopes, only one type of fluorescent label can be observed. This study introduces multispectral intravital video microscopy, which combines bright-field and fluorescence microscopy in a standard light microscope. The technique enables simultaneous real-time observation of fluorescently-labeled structures in relation to their direct physical surroundings. The advancement provides context for the orientation, movement, and function of labeled structures in the microcirculation.

• Journal of the Microelectronics and Packaging Society
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• v.21 no.4
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• pp.25-31
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• 2014

Bioimaging has advanced the field of nanomedicine, drug delivery, and tissue engineering by directly visualizing the dynamic mechanism of diagnostic agents or therapeutic drugs in the body. In particular, wide-field, planar, near-infrared (NIR) fluorescence imaging has the potential to revolutionize human surgery by providing real-time image guidance to surgeons for target tissues to be resected and vital tissues to be preserved. In this review, we introduce the principles of NIR fluorescence imaging and analyze currently available NIR fluorescence imaging systems with special focus on optical source and packaging. We also introduce the evolution of the FLARE intraoperative imaging technology as an example for image-guided surgery.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.12
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• pp.5103-5115
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• 2015

In radar imaging, a target is usually consisted of a few strong scatterers which are sparsely distributed. In this paper, an improved sparse signal recovery algorithm based on smoothed l₀ (SL0) norm method is proposed to achieve high resolution ISAR imaging with limited pulse numbers. Firstly, one new smoothed function is proposed to approximate the l₀ norm to measure the sparsity. Then a single loop step is used instead of two loop layers in SL0 method which increases the searching density of variable parameter to ensure the recovery accuracy without increasing computation amount, the cost function is undated in every loop for the next loop until the termination is satisfied. Finally, the new set of solution is projected into the feasible set. Simulation results show that the proposed algorithm is superior to the several popular methods both in terms of the reconstruction performance and computation time. Real data ISAR imaging obtained by the proposed algorithm is competitive to several other methods.

• Nuclear Medicine and Molecular Imaging
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• v.41 no.4
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• pp.265-271
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• 2007

Radionuclide therapy has been an important field in nuclear medicine. In radionuclide therapy, relevant evaluation of Internally absorbed dose is essential for the achievement of efficient and sufficient treatment of incurable disease, and can be accomplish by means of accurate measurement of radioactivity in body and its changes with time. Recently, the advances of nuclear medicine imaging and multi modality imaging processing techniques can provide change of more accurate and easier measurement of the measures commented above, in cooperation of conventional imaging based approaches. in this review, basic concept for internal dosimetry using nuclear medicine imaging is summarized with several check points which should be considered In real practice.

• Journal of Biomedical Engineering Research
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• v.27 no.3
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• pp.117-124
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• 2006

Recently, active research has been going on to measure the elastic modulus of human soft tissue with medical ultrasound imaging systems for the purpose of diagnosing cancers or tumors which have been difficult to detect with conventional B-mode imaging techniques. In this paper, a real-time ultrasonic elasticity imaging system is implemented in software on a Pentium processor-based ultrasonic diagnostic imaging system. Soft tissue is subjected to external vibration, and the resulting tissue displacements change the phase of received echoes, which is in turn used to estimate tissue elasticity. It was confirmed from experiment with a phantom that the implemented elasticity imaging system could differentiate between soft and hard regions, where the latter is twice harder than the former, while operating at an adequate frame rate of 20 frames/s.

• Geotechnical Engineering
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• v.26 no.9
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• pp.33-47
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• 2010

Underground constructions continue to provide challenges to Geotechnical Engineers yet they pose the best opportunities for development and deployment of advance technologies for analysis, design and construction. The reason for this is that, by virtue of the nature of underground constructions, more data and information on ground characteristics and response become available as the construction progresses. However, due to several barriers, these data and information are rarely, if ever, utilized to modify and improve project design and construction during the construction stage. To enable the use of evolving realtime data and information, and adaptively modify and improve design and construction, the paper presents an analysis and design system, called AMADEUS, for underground projects. AMADEUS stands for Adaptive, real-time and geologic Mapping, Analysis and Design of Underground Space. AMADEUS relies on recent advances in IT (Information Technology), particularly in digital imaging, data management, visualization and computation to significantly improve analysis, design and construction of underground projects. Using IT and remote sensors, real-time data on geology and excavation response are gathered during the construction using non-intrusive techniques which do not require expensive and time-consuming monitoring. The real-time data are then used to update geological and geomechanical models of the excavation, and to determine the optimal, construction sequences and stages, and structural support. Virtual environment (VE) systems are employed to allow virtual walk-throughs inside an excavation, observe geologic conditions, perform virtual construction operations, and investigate stability of the excavation via computer simulation to steer the next stages of construction.

• Nuclear Engineering and Technology
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• v.52 no.10
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• pp.2250-2261
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• 2020

Accurate localization of radioactive materials is crucial in homeland security and radiological emergencies. Coded-aperture gamma camera is an interesting solution for such applications and can be developed into portable real-time imaging devices. However, traditional reconstruction methods cannot effectively deal with signal-independent noise, thereby hindering low-noise real-time imaging. In this study, a novel reconstruction method with excellent noise-suppression capability based on a multi-layer perceptron (MLP) is proposed. A coded-aperture gamma camera based on pixel detector and coded-aperture mask was constructed, and the process of radioactive source imaging was simulated. Results showed that the MLP method performs better in noise suppression than the traditional correlation analysis method. When the Co-57 source with an activity of 1 MBq was at 289 different positions within the field of view which correspond to 289 different pixels in the reconstructed image, the average contrast-to-noise ratio (CNR) obtained by the MLP method was 21.82, whereas that obtained by the correlation analysis method was 5.85. The variance in CNR of the MLP method is larger than that of correlation analysis, which means the MLP method has some instability in certain conditions.

• Journal of the Korean Solar Energy Society
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• v.39 no.6
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• pp.55-65
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• 2019

With the rapid development of the national industry, the importance of electrical safety was recognized because of a lot of new electrical equipment are installing and the electrical accidents have been occurring annually. Today, the electrical equipments is inspect by using the portable Infrared thermal imaging camera. but the most negative element of using the camera is inspected for only state of heating, the reliable diagnosis is depended with inspector's knowledge, and real-time monitoring is impossible. This paper present the infrared thermal imaging safety diagnosis system. This system is able to monitor in real time, predict the state of fault, and diagnose the state with analysis of thermal and power data. The system consists of a main processor, an infrared camera module, the power data acquisition board, and a server. The diagnostic algorithm is based on a mathematical model designed by analyzing the Pearson's Correlation Coefficient between temperature and power data. To test the prediction algorithm, the simulations were performed by damaging the terminals or cables on the switchboard to generate a large amount of heat. Utilizing these simulations, the developed prediction algorithm was verified.

• Imaging Science in Dentistry
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• v.52 no.1
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• pp.93-101
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• 2022

Purpose: This study compared the effectiveness of complementary metal-oxide semiconductors (CMOS) and photostimulable phosphor (PSP) plates as intraoral imaging systems in terms of time efficacy, patient comfort, and subjective image quality assessment in real clinical settings. Materials and Methods: Fifty-eight patients (25 women and 33 men) were included. Patients were referred for a full-mouth radiological examination including 1 bitewing radiograph (left and right) and 8 periapical radiographs for each side (left maxilla/mandible and right maxilla/mandible). For each patient, 1 side of the dental arch was radiographed using a CMOS detector, whereas the other side was radiographed using a PSP detector, ensuring an equal number of left and right arches imaged by each detector. Clinical application time, comfort/pain, and subjective image quality were assessed for each detector. Continuous variables were summarized as mean±standard deviation. Differences between detectors were evaluated using repeated-measures analysis of variance. P<0.05 was accepted as significant. Results: The mean total time required for all imaging procedures with the CMOS detector was significantly lower than the mean total time required for imaging procedures with PSP (P<0.05). The overall mean patient comfort scores for the CMOS and PSP detectors were 4.57 and 4.48, respectively, without a statistically significant difference (P>0.05). The performance of both observers in subjectively assessing structures was significantly higher when using CMOS images than when using PSP images for all regions (P<0.05). Conclusion: The CMOS detector was found to be superior to the PSP detector in terms of clinical time efficacy and subjective image quality.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.12 no.6
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• pp.78-86
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• 2013

In this paper, we propose design of a high-performance vehicle imaging information system for an efficient vehicle imaging stabilization. The proposed system was designed the algorithm by divided as motion estimation and motion compensation. The motion estimation were configured as local motion vector estimation and irregular local motion vector detection, global motion vector estimation. The motion compensation was corrected for the four directions for compensate to the shake of vehicle video image using estimate GMV. The designed algorithm were designed the motion compensation technology chip by applied to IP for vehicle imaging stabilization. In this paper, the experimental results of the proposed vehicle imaging information system were proved to the effectiveness by compared with other methods, because imaging stabilization of moving vehicle was not used of memory by processing real-time. Also, it could be obtained to reduction effect of calculation time by arithmetic operation through to block matching.