• Nutrition Research and Practice
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• 제15권2호
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• pp.160-172
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• 2021

BACKGROUND/OBJECTIVES: Nutritional status and food intake during pregnancy and lactation can affect fetal programming. In the current metabolic syndrome epidemic, high-fructose diets have been strongly implicated. This study investigated the effect of maternal high-fructose intake during pregnancy and lactation on the development of metabolic syndrome in adult offspring. SUBJECTS/METHODS: Drinking water with or without 20% fructose was administered to female C57BL/6J mice over the course of their pregnancy and lactation periods. After weaning, pups ate regular chow. Accu-Chek Performa was used to measure glucose levels, and a tail-cuff method was used to examine systolic blood pressure. Animals were sacrificed at 7 months, their livers were excised, and sections were stained with Oil Red O and hematoxylin and eosin (H&E) staining. Kidneys were collected for gene expression analysis using quantitative real-time Polymerase chain reaction. RESULTS: Adult offspring exposed to maternal high-fructose intake during pregnancy and lactation presented with heavier body weights, fattier livers, and broader areas under the curve in glucose tolerance test values than control offspring. Serum levels of alanine aminotransferase, aspartate aminotransferase, glucose, triglycerides, and total cholesterol and systolic blood pressure in the maternal high-fructose group were higher than that in controls. However, there were no significant differences in mRNA expressions of renin-angiotensin-aldosterone system genes and sodium transporter genes. CONCLUSIONS: These results suggest that maternal high-fructose intake during pregnancy and lactation induces metabolic syndrome with hyperglycemia, hypertension, and dyslipidemia in adult offspring.

• 한국정보통신학회논문지
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• 제26권2호
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• pp.223-229
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• 2022

매년 날씨가 추워지는 동절기에는 전기 사용량이 급증하는 특징을 보인다. 많은 전기를 사용하면서 인구 밀도가 높은 시장, 목욕탕, 아파트 등의 건물들의 전기 시설의 누전으로 인해 화재 발생이 늘어나고 있다. 이러한 누전화재의 원인은 대부분 전선의 노후화로 인해 사용량이 증가되어 과도하게 걸리는 부하를 견디지 못하고 전선피복이 녹아내려 주변의 발화물질로 인하여 발생하게 된다. 본 논문에서는 과부하센서, VoC센서, 과열센서로 구성된 복합 센서를 통해 전선에 발생하는 부하 및 과열을 측정하며, 이 때 발생된 유독가스를 검출하고 게이트웨이를 활용하여 서버에 로깅하는 시스템을 구현한다. 이를 바탕으로 빅데이터 분석을 진행하여 실시간으로 전기화재를 예측, 경보 및 차단이 가능한 플랫폼과 모의 화재발생 실험이 가능한 시뮬레이터를 개발한다.

• Clinical and Experimental Reproductive Medicine
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• 제49권3호
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• pp.175-184
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• 2022

Objective: The aim of this study was to evaluate the impacts of platelet-rich plasma (PRP) and conditioned medium (CM) derived from endometrial stromal cells on mouse preantral follicle culture in a two-dimensional system to produce competent mature oocytes for fertilization. Methods: In total, 240 preantral follicles were isolated from female mouse ovarian tissue and divided into four groups. The preantral follicles were isolated three times for each group and then cultured, respectively, in the presence of alpha minimum essential medium (control), PRP, CM, and PRP+CM. The in vitro growth, in vitro maturation, and cleavage percentage of the preantral follicles were investigated. Immunocytochemistry (IHC) was also conducted to monitor the meiotic progression of the oocytes. Additionally, the mRNA expression levels of the two folliculogenesis-related genes (Gdf9 and Bmp15) and two apoptosis-related genes (Bcl2 and Bax) were investigated using real-time polymerase chain reaction. Results: In the PRP, CM, and PRP+CM groups, the preantral follicle maturation (evaluated by identifying polar bodies) were greater than the control group. The cleavage rate in the CM, and PRP+CM groups were also greater than the control group. IHC analysis demonstrated that in each treatment group, meiotic spindle was normal. In the PRP+CM group, the gene expression levels of Bmp15, Gdf9, and Bcl2 were greater than in the other groups. The Bax gene was more strongly expressed in the PRP and control groups than in the other groups. Conclusion: Overall, the present study suggests that the combination of CM and PRP can effectively increase the growth and cleavage rate of mouse preantral follicles in vitro.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권11호
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• pp.3950-3969
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• 2021

Radio Frequency (RF)-based indoor localization technologies play significant roles in various Internet of Things (IoT) services (e.g., location-based service). Most such technologies require that all the devices comply with a specified technology (e.g., WiFi, ZigBee, and Bluetooth). However, this requirement limits its application scenarios in today's IoT context where multiple devices complied with different standards coexist in a shared environment. To bridge the gap, in this paper, we propose a cross-technology localization approach, which is able to localize target nodes using a different type of devices. Specifically, the proposed framework reuses the existing WiFi infrastructure without introducing additional cost to localize Non-WiFi device (i.e., ZigBee). The key idea is to leverage the interference between devices that share the same operating frequency (e.g., 2.4GHz). Such interference exhibits unique patterns that depend on the target device's location, thus it can be leveraged for cross-technology localization. The proposed framework uses Principal Components Analysis (PCA) to extract salient features of the received WiFi signals, and leverages Dynamic Time Warping (DTW), Gradient Boosting Regression Tree (GBRT) to improve the robustness of our system. We conduct experiments in real scenario and investigate the impact of different factors. Experimental results show that the average localization accuracy of our prototype can reach 1.54m, which demonstrates a promising direction of building cross-technology technologies to fulfill the needs of modern IoT context.

• 한국구조물진단유지관리공학회 논문집
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• 제25권5호
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• pp.1-7
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• 2021

본 연구에서는 대형 시설물의 재난 모니터링을 위해 시설물에서 발생 가능한 붕괴 및 화재 사고를 감지하고, 재난 상황 발생 시 IoT 기반의 시설물 내부 상황 인지를 위한 커스터마이징 비콘을 개발하고자 하였다. 기존 변형률 센서를 이용한 데이터 계측의 경우 유선으로 변형률 센서를 연결하여 계측하였지만, 본 연구는 이를 무선으로 변경하여 실시간으로 구조물 변형의 유·무를 모니터링이 가능하도록 하였다. 이 과정에서 휘트스톤 브릿지를 이용하기 위해 커스터마이징 비콘에 연결이 가능한 변형률 센서 모듈을 제작하였으며, 계측 데이터를 원격으로 확인하기 위한 시스템 구성을 진행하였다. 계측 데이터 검증을 위해 차세대융합기술연구원 15층 내에 10개의 커스터마이징 비콘과 2개의 게이트웨이를 설치하였으며, 계측 데이터 분석 결과 변형률 데이터값이 7~8 사이에 분포하는 것을 확인하였다.

• Fisheries and Aquatic Sciences
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• 제25권3호
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• pp.151-157
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• 2022

Various approaches have been applied to transform aquaculture from a manual, labour-intensive industry to one dependent on automation technologies in the era of the fourth industrial revolution. Technologies associated with the monitoring of physical condition have successfully been applied in most aquafarm facilities; however, real-time biological monitoring systems that can observe fish condition and behaviour are still required. In this study, we used a video recorder placed on top of a fish tank to observe the swimming patterns of rock bream (Oplegnathus fasciatus), first one fish alone and then a group of five fish. Rock bream in the video samples were successfully identified using the you-only-look-once v3 algorithm, which is based on the Darknet-53 convolutional neural network. In addition to recordings of swimming behaviour under normal conditions, the swimming patterns of fish under abnormal conditions were recorded on adding an anaesthetic or lowering the salinity. The abnormal conditions led to changes in the velocity of movement (3.8 ± 0.6 cm/s) involving an initial rapid increase in speed (up to 16.5 ± 3.0 cm/s, upon 2-phenoxyethanol treatment) before the fish stopped moving, as well as changing from swimming upright to dying lying on their sides. Machine learning was applied to datasets consisting of normal or abnormal behaviour patterns, to evaluate the fish behaviour. The proposed algorithm showed a high accuracy (98.1%) in discriminating normal and abnormal rock bream behaviour. We conclude that artificial intelligence-based detection of abnormal behaviour can be applied to develop an automatic bio-management system for use in the aquaculture industry.

• 한국재난정보학회 논문집
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• 제18권3호
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• pp.487-494
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• 2022

연구목적: 본 연구는 시대적 환경의 변화에 따른 경찰의 다양한 활동에 대한 성과를 효율적으로 증진시킬 수 있는 메타버스 기반 경찰교육훈련모델을 제안하고자 한다. 연구방법: HMD과 햅틱기술을 이용하여 표현되는 Avatar Controller를 생성하고, Network Interface에 접속하여 Cloud Education Server에서의 지휘통제모듈과 교육훈련콘텐츠모듈, 분석모듈 등을 통하여 개인 또는 팀 단위로 교육훈련 할 수 있다. 연구결과: 본 연구의 제안모델에서는 개인이나 팀 단위의 메타버스 기반 교육훈련 시 지휘통제모듈을 접목시킴으로써 테러나 범죄 상황 전반에 대하여 지휘감독요원들이 실시간으로 상황을 모니터링하여 지휘통제 하에 대응훈련을 하게 함으로써 팀원들 간의 유기적인 협업훈련도 가능하게 하였다. 결론: 메타버스를 기반으로 한 개인 또는 팀 단위의 경찰교육훈련은 몰입감, 상호작용 그리고 다양한 상황에서의 신속한 판단 등을 바탕으로 현실과 거의 흡사한 환경을 조성함으로써 보다 더 효율적이고 안전적인 교육훈련환경을 제공할 수 있기 때문에 향후 각국에서 메타버스를 기반으로 한 교육훈련 대응모델들은 지속적으로 성장하며 교육훈련에 있어서 새로운 대안으로 제시될 것으로 기대된다.

• International Journal of Computer Science & Network Security
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• 제22권10호
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• pp.400-405
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• 2022

Legislative approaches to regulating the digital sex industry are increasingly being debated at the international and national levels. There is a trend showing an increased interest in the decriminalization of sex work. At the same time, in many countries, activities related to digital prostitution remain criminalized. In this regard, it is important to analyze the international legal experience of the criminalization and decriminalization of digital prostitution, as well as to pay attention to the key problematic issues that arise during the criminalization and decriminalization of such an issue. The object of the study is the international experience of criminalization and decriminalization of digital prostitution. The subject of the study is social relations that arise, change, and cease during the criminalization and decriminalization of digital prostitution. The research methodology consists of such methods as philosophical, logical, special-legal, system analysis methods, and formal-dogmatic methods. Research results. As a result of the study of the international legal experience of criminalization and decriminalization of digital prostitution, it was concluded that the criminalization and/or decriminalization of digital prostitution is treated differently in different countries. Workers in this industry advocate decriminalization, not legalization, because decriminalization puts power directly in the hands of sex workers and creates no legal barriers. Countries that have decriminalized digital prostitution believe that sex work is real work and should be treated respectfully, and banning resources such as OnlyFans is not in favor of such workers. Regarding positions on the criminalization of prostitution, countries use different models of such criminalization, including the model of legalization of digital prostitution, which, on the one hand, allows prostitution, but establishes criminal liability for deviations from the rules established by the state.

• 한국군사과학기술학회지
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• 제26권1호
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• pp.91-101
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• 2023

Modeling and Simulation(M&S) technology has been widely used to solve constraints such as time, space, safety, and cost when we implement the same development and test environments as real warfare environments to develop, test, and evaluate weapon systems for the last several decades. The integration and test environments employed for development and test & evaluation are required to provide Live Virtual Construction(LVC) simulation environments for carrying out requirement analysis, design, integration, test and verification. Additionally, they are needed to provide computing environments which are possible to reconfigure computing resources and software components easily according to test configuration changes, and to run legacy software components independently on specific hardware and software environments. In this paper, an Integration Test and Simulation for Engagement Control(ITSEC) bed using a bare-metal virtualization mechanism is proposed to meet the above test and simulation requirements, and it is applied and implemented for an air missile defense system. The engagement simulation experiment results conducted on air and missile defense environments demonstrate that the proposed bed is a sufficiently cost-effective and feasible solution to reconfigure and expand application software and computing resources in accordance with various integration and test environments.

• 센서학회지
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• 제32권3호
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• pp.131-139
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• 2023

Ascorbic acid plays a crucial role in the regulation of neurotransmitters and enzymes in the central nervous system. Maintaining an optimal level of ascorbic acid, which is between 0.6-2 mg/dL, is vital for preventing oxidative stress and associated health conditions, such as cancer, diabetes, and liver disease. Therefore, the detection of ascorbic acid is of the utmost importance. Electrochemical sensing has gained significant attention among the various detection methods, owing to its simplicity, speed, affordability, high selectivity, and real-time analysis capabilities. However, conventional electrodes have poor signal response, which has led to the development of modified electrodes with better signal response and selectivity. Carbon nanotubes (CNTs) and their composites have emerged as promising materials for the electrochemical detection of ascorbic acid. CNTs possess unique mechanical, electrical, and chemical properties that depend on their structure, and their large surface area and excellent electron transport properties make them ideal candidates for electrochemical sensing. Recently, various CNT composites with different materials and nanoparticles have been studied to enhance the electrochemical detection of ascorbic acid. Therefore, this review aims to highlight the significance of CNTs and their composites for improving the sensitivity and selectivity of ascorbic acid detection. Specifically, it focuses on the use of CNTs and their composites in electrochemical sensing to revolutionize the detection of ascorbic acid and contribute to the prevention of oxidative stress-related health conditions. The potential benefits of this technology make it a promising area for future research and development.