• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.37 no.5
• /
• pp.396-402
• /
• 2011

Introduction: Epidermal growth factor is a single-chain polypeptide consisting of 53 amino acids with potent mitogenic activity that stimulates the proliferation of a range of normal and neoplastic cells through an interaction with its specific receptor (epidermal growth factor receptor, EGFR). This interaction plays a key role in tumor progression including the induction of tumor cell proliferation. An increased EGFR copy number have been associated with a favorable response to EGFR tyrosine kinase inhibitors therapy. In contrast, K-ras mutations tend to predict a poor response to such therapy. The aim of this study was to determine the correlation between the clinicopathological factors and the up-regulation of EGFR expression and Kras mutations in oral squamous cell carcinoma. Materials and Methods: This study examined the immunohistochemical staining of EGFR, K-ras mutation detection with peptide nucleic acid (PNA)-based real-time polymerase chain reaction (PCR) clamping in 20 specimens from 20 patients with oral squamous cell carcinoma. Results: 1. In the immunohistochemical study of poorly differentiated and invasive oral squamous cell carcinoma, a high level of EGFR staining was observed. The correlation between immunohistochemical EGFR expression and histological differentiation, as well as the tumor size of the specimens was significant (Pearson correlation analysis, significance [r] >0.5, P<0.05). 2. In PNA-based real-time PCR clamping analysis, a K-ras mutation was not detected in all specimens. Conclusion: These findings suggest that the up-regulation of the EGFR may play a role in the progression and invasion of oral squamous cell carcinoma that is, independent of a K-ras mutation.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.9 no.5
• /
• pp.1002-1011
• /
• 2005

In this paper. we design and implement a bi-directional broadcasting system, so called return channel server, to allow users to participate in a broadcasting program by using a hi-directional interaction channel. To provide user participation in a program and reflect the user's opinions or responses in real time, the return channel server can be viewed as consisting of four major functional modules: a control module, network interface module, DBMS module, and real-time content authoring module. To construct a return channel server that has a service independent architecture, we designed a return channel server to include the hierarchical structure. The presented return channel server consists of two parts: an RCSAE(return channel server application environment) and RCSA(return channel server application). An RCSA is composed of an execution code and a parameter for executing the execution code. RCSA defines the procedures for providing a specific broadcasting program using the return channel server. On the other hand, an RCSAE provides the environment for the execution of RCSAS. By adopting RCSAE and RCSA, we construct the return channel server that has a service-independent architecture which are shown by the test.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2003.10a
• /
• pp.227-232
• /
• 2003

Non-intrusive methods based on active remote IR illumination for eye tracking is important for many applications of vision-based man-machine interaction. One problem that has plagued those methods is their sensitivity to lighting condition change. This tends to significantly limit their scope of application. In this paper, we present a new real-time eye detection and tracking methodology that works under variable and realistic lighting conditions. eased on combining the bright-pupil effect resulted from IR light and the conventional appearance-based object recognition technique, our method can robustly track eyes when the pupils are not very bright due to significant external illumination interferences. The appearance model is incorporated in both eyes detection and tracking via the use of support vector machine and the mean shift tracking. Additional improvement is achieved from modifying the image acquisition apparatus including the illuminator and the camera.

• Journal of Internet Computing and Services
• /
• v.8 no.2
• /
• pp.1-13
• /
• 2007

GPS/GIS and RFID technologies have been changing the paradigm af our society toward ubiquitous era. Especially, geographically distributed mobile agents with transporting objects need to be automatically recognizable and traceable under certain conditions. To do this, fundamental theories and technologies are required to specify and verify spatial and temporal behaviors of agents on geographical space. This paper presents a new formal method, called Calculus of Real-Time Distribution, Mobility, and Interaction (CaRDMI), for this purpose. For specification, CaRDMI defines a map, mobile agents with transporting objects. The movement of on agent is represented by a path on the map, consisting of a list of nodes and a list of edges with spatial and temporal constraints. Interactive constraints among agents are represented by synchronization modes on objects at nodes. These constraints are distinguishable features of CaRDMI from other methods. Especially, many-to-many timed synchronization constraints are noticeable. For verification, CaRDMI presents the spatial, temporal and interactive deduction rules and the spatial and temporal equivalence relations.

• Korean Journal of Computational Design and Engineering
• /
• v.13 no.4
• /
• pp.265-272
• /
• 2008

The flow of technology is going to human-oriented direction, from the time when the computer was first invented, to now where new computing environment using mobile and global network are everywhere. On that technology flow, ubiquitous is being suggested as new paradigm of computing environment. Augmented Reality is one of ubiquitous technologies that provide the interactions between human and computer. By adding computer-generated information to real information and their interaction, user can get the improved and more knowledgeable information about real world. The purpose of this paper is to show the possibility of applying vision based augmented reality to maintenance of product system.

• East Asian Journal of Business Economics (EAJBE)
• /
• v.1 no.1
• /
• pp.8-16
• /
• 2013

Purpose: The objective of this paper is to identify and assess the contribution of budgetary, monetary and institutional shocks affecting the Tunisian economy over the period 1976-2003. The methodology used is vector autoregressive models and structural recent techniques for the analysis of time series related. The empirical results show a significant relationship between the supply shock and institutions on the one hand, and between institutional shocks and economic activity on the other hand. Research Design, Data and Methodology: As part of this section we will try to identify and assess the contribution of various shocks to macroeconomic variables' fluctuations for the Tunisian economy. The study period is: 1976-2003 and observations are annual. Results: The real business cycle theory argues that fluctuations in aggregate economic activity are the result of the interaction of the only real factors namely agents' preferences, technological opportunities, factor endowments and possibly certain institutional constraints. Conclusions: The lowest contribution to the variability of these rights is the monetary shock. As for "civil liberties", the largest share of their variability is the shock relating to the "political rights" during the first four periods .

• Journal of Information Science Theory and Practice
• /
• v.3 no.4
• /
• pp.19-34
• /
• 2015

Evaluation of retrieval systems is mostly limited to laboratory settings and rarely considers changes of performance over time. This article presents an evaluation of retrieval systems for internal Web site search systems between the years 2006 and 2011. A holistic evaluation methodology for real Web sites was developed which includes tests for functionality, search quality, and user interaction. Among other sites, one set of 20 Web site search systems was evaluated three times in different years and no substantial improvement could be shown. It is surprising that the communication between site and user still leads to very poor results in many cases. Overall, the quality of these search systems could be improved, and several areas for improvement are apparent from our evaluation. For a comparison, Google’s site search function was also tested with the same tasks.

• Wind and Structures
• /
• v.16 no.5
• /
• pp.477-490
• /
• 2013

This paper presents results of calculations performed according to our own semi-empirical mathematical model of critical vortex excitation. All calculations are carried out using own computer program, which allows the simulation of both the across-wind action caused by vortices and the lateral response of analysed structures. Vortex excitation simulations were performed in real time taking into account wind-structure interaction. Several structures of circular cross-sections were modelled using a FEM program and calculated under the action of critical vortex excitation. Six steel chimneys, six concrete chimneys and two concrete towers were considered. The method of selection and estimation of the experimental parameters describing the model are also presented. Finally, the results concerning maximum lateral top displacements of the structures are compared with available full-scale data for steel and concrete chimneys.

• International Journal of Advanced Culture Technology
• /
• v.11 no.1
• /
• pp.389-394
• /
• 2023

Based on intelligent visual information and 5G, this paper studies the intelligent visual communication of landscape bamboo buildings, and provides a new method of intelligent perception and interactive computing for the real world, which can represent, model, Perception and cognition; through the integration of virtual and real, the situational understanding of the human-machine-material fusion environment and the interaction with nature. The 5G network can well meet the combination of high-bandwidth uplink transmission and low-latency downlink control. At the same time, 5G-based AR intelligent inspection, remote operation and maintenance guidance, and machine vision inspection. Taking the bamboo building as an example, through field inspections to analyze tourism Bamboo buildings before and after development, and the intelligentization of bamboo buildings based on 5G and visual modeling.

• Archives of design research
• /
• v.15 no.2
• /
• pp.59-70
• /
• 2002

The psychological system of human beings has gone through changes from material satisfaction to spiritual satisfaction. That is, $\ulcorner$From real goods to feel goods$\lrcorner$: much attention is not paid to physical consumption of real products but to consumption of time containing information value such as services capable of enriching and entertaining life. Entertainment is a cultural industry based on mass consumption culture. In this context, this research is designed to look into the entertainment tendency of the industrial areas and to take a look at various forms of attraction serving as the factor of absorption to users. The study indicates that the moderns impose much value on invisible goods such as experience. And the most popularized method is to appeal to clients for sensory interaction by presenting the experience of joy. Entertainment in a true sense is generated on the basis of creativity, which is a product of intuition and efforts directed toward the understanding of emotional ties with the general public characterized by uncertainty.