• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 1999년도 춘계 학술대회논문집
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• pp.192-198
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• 1999

The present study proposes modified temperature-dependent non-Newtonian viscosity model and investigates flow characters and heat transfer enhancement of the viscoelastic non-Newtonian fluid in a 2:1 rectangular duct. The proposed modified temperature dependent viscosity model has non-zero value near the high temperature and high shear rate region while on the existing viscosity models have zero value. Two versions of thermal boundary conditions involving difference combination of heated walls and adiabatic walls are analyzed in this study. The combined effect of temperature dependent viscosity, buoyancy, and secondary flow caused by second normal stress difference are ail considered. The Reiner-Rivlin model is adopted as a viscoelastic fluid model to simulate the secondary flow caused by second normal stress difference. Calculated Nusselt numbers by the modified temperature-dependent viscosity model gives under prediction than the existing temperature-dependent viscosity model in the regions of thermally developed with same secondary normal stress difference coefficients with experimental results in the regions of thermally developed. The heat transfer enhancement of the viscoelastic fluid in a 2:1 rectangular duct is highly dependent on the secondary flow caused by the magnitude of second normal stress difference.

• Journal of Radiation Protection and Research
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• 제38권4호
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• pp.179-184
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• 2013

The biological effects of radiation are dependent on the dose rate and dose of radiation. In this study, effects of dose and dose rate using whole body radiation on plasma cytokines and blood count from male BALB/c mice were evaluated. We examined the blood and cytokine changes in mice exposed to a low (3.49m Gy $h^{-1}$) and high (2.6 Gy $min^{-1}$) dose rate of radiation at a total dose of 0.5 and 2 Gy, respectively. Blood from mice exposed to radiation were evaluated using cytokine assays and complete blood count. Peripheral lymphocytes and neutrophils decreased in a dose dependent manner following high dose rate radiation. The peripheral lymphocytes population remained unchanged following low dose rate radiation; however, the neutrophils population increased after radiation. The sera from these mice exhibited elevated levels of flt3 ligand and granulocyte-colony-stimulating factor (G-CSF), after high/low dose rate radiation. These results suggest that low-dose-rate radiation does not induce blood damage, which was unlike high-dose-rate radiation treatment; low-dose-rate radiation exposure activated the hematopoiesis through the increase of flt3 ligand and G-CSF.

• Journal of applied mathematics & informatics
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• 제18권1_2호
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• pp.311-320
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• 2005

Studies in the evolutionary biology of aging require good estimates of the age-dependent mortality rate coefficient (one of the Gompertz parameters). In this paper we introduce an alternative algorithm for estimating this parameter. And we discuss the sensitivity of the estimates to changes in the other model parameters.

• Bulletin of the Korean Chemical Society
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• 제7권6호
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• pp.416-421
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• 1986

The solvent coordination effect on the excited state processes of Mg(II)- and Zn(II)-phthalocyanines has been described. The triplet state of these compounds decays with mixed first and second order kinetics or mainly second order kinetics depending on the solvents used. The first order component of the rate constants decrease along with the series, dimethylsulfoxide (5-coordinated), 1-chloronaphthalene (4-coordinated) and piperidine (6-coordinated), while the second order rate constant is dependent on the diffusion rate constant of the solvents. The excited state quenching by methylviologen or p-benzoquinone is discussed. And ion recombination rate constant is given.

• 대한기계학회논문집
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• 제9권5호
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• pp.539-547
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• 1985

본 논문에서는 이상과 같은 연구현상을 배경으로 응력비 R.geq.0인 사인응력파 에서도 사이클의존형 크랙전파가 공존하는가, 공존한다면 그 전이를 결정짓는 조건을 구하기 위해, 대표적인 고온용 재료인 SUS 304강을 이용하여 온도 650.deg. C, 대기중에서 반복속도 .nu., 응력비 R, 응력레벨 .sigma.$_{maxo}$등의 실험조건을 바꾸어 고온저사이클 피로실험을 하였다. 또 이 현상의 기초과정을 이해하는데 도움을 주기 위하여 파면 관찰을 행하였다.

• BMB Reports
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• 제32권3호
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• pp.226-231
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• 1999

In vitro effects of acetone on cytochrome P450 (P450)-dependent benzo(a)pyrene (B(a)P) hydroxylation supported by cumene hydroperoxide (CuOOH) or NADPH/$O_2 $ systems were studied using 3-methylcholanthrene-pretreated rat liver microsomes. The maximal rate of B(a)P hydroxylation at constant concentration ($80\;{\mu}M)$ of the substrate was observed in the presence of $30\;{\mu}M$ CuOOH. However, at concentrations higher than $30\;{\mu}M$ CuOOH the hydroxylation rates were rapidly decreased. In contrast to CuOOH, at a concentration of $200\;{\mu}M$ NADPH, B(a)P hydroxylation rate reached a plateau. At concentrations higher than $200\;{\mu}M$ NADPH, the rates of substrate hydroxylation were maintained at the maximal rate with no inhibition. Acetone at 1% (v/v) enhanced both CuOOH- and NADPH/$O_2$-supported B(a)P hydroxylation at the optimal concentrations of the cofactors. At concentrations higher than 1% (v/v) acetone, substrate hydroxylation was sterero specific under the support of these two cofactors; it was strongly enhanced with $30\;{\mu}M$ CuOOH, but rather inhibited in the $200\;{\mu}M$> NADPH/$0_2 $ system. The lipid peroxidation rate induced during CuOOH-supported P450-dependent B(a)P hydroxylation was increased as CuOOH concentrations were increased. Acetone in the concentration range of 2.5~7.5%(v/v) inhibited lipid peroxidation during CuOOH supported B(a)P hydroxylation. The finding that CuOOH-supported B(a)P hydroxylation is greatly enhanced by acetone suggests that acetone may contribute more to the activation of oxygen (for the insertion of oxygen into the substrate) in the presence of CuOOH than with NADPH/$O_2$. Acetone may also contribute to the partial inhibition of destruction of microsomal membranes by lipid peroxidation.

• 한국패류학회지
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• 제26권1호
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• pp.91-95
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• 2010

Density-dependant growth and mortality rate of Manila clam Ruditapes philippinarum reared in net cages was investigated in Gomso Bay, Korea where unusually high mortality of clams has been reported. For the experiment, four groups of clam cages were set up with a density of $2,000clams/m^2$ (group A), $1,000clams/m^2$ (group B), $500clams/m^2$ (group C) and $100clams/m^2$ (group D). Mortality and growth of clams in each experimental cage was monitored biweekly from May 2001 to September 2001. Highest mortality in group A was observed in late August, while highest mortality of rest groups was observed in early September. In September, the cumulative mortality in group A was 99%, while it was 93.2% in group B, 91.2% in group C and 88% in group D. Shell growth rate of clams in thecages was found to be density dependent; monthly shell length increase was 0.67 mm in group A, 1.33 mm in group B, 1.63 mm in group C and 1.71 mm in group D. Our study indicated that clam growth and mortality in the Bay is density dependent and the growth and survival rate is negatively correlated with the density.

• 한국임상수의학회지
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• 제22권3호
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• pp.220-227
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• 2005

Although ketamine has been used in the field of anesthetic medicine for its safety and favourable respiratory effects, the cardiovascular effects of ketamine is still controversial. To clarify the action and mechanism of ketamine upon cardiovascular system, arterial blood pressure, tension of aortic ring, left ventricular developed pressure and heart rate were measured in rats, Ketamine produced two types of effects on arterial blood pressure in anesthetized rats; monophasic effect (blood pressure lowering) and biphasic effect (initial transient blood pressure increasing following sustained lowering), The ketamine-induced lowering of aterial blood pressure showed a concentration-dependent manner, inhibited by the pretreament of $MgCl_2$ and potentiated by the pretreatment of $CaCl_2$. The ketamine-induced lowering of aterial blood pressure was suppressed by the pretreatment of nifedipine, verapamil or lidocaine. In phenylephrine-precontracted endothelium intact (+E) aortic rings, ketamine sometimes caused a small enhancement of contraction ($112.5{\pm}3.6{\%}$). However, in many experiments, ketamine produced a concentration-dependent relaxation in +E aortic rings precontracted with either phenylephrine or KCl. Ketamine-induced relaxation was significantly greater in KCl-precontracted strips than phenylephrine-precontracted strips. In phenylephrine-precontracted +E aortic rings, the ketamine-induced vasorelaxation was not suppressed by endothelium removal or by the pretreatment of a nitric oxide synthase inhibitors, L-$N^G$-nitro-arginine and a guanylate cyclase inhibitors, methylene blue, suggesting that the ketamine-induced vasorelaxation is not dependent on the endothelial function. In addition, ketamine elicited an increase in left ventricular developed pressure in perfused hearts accompanied by decrease in heart rate. These results suggest that ketamine could evoke a hypotension due to vasorelaxation and decrease in heart rate in rats. The inhibitory effect of cardiovascular system might be associated with modulation of $Ca^{2+}$ homeostasis.

• 감성과학
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• 제11권4호
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• pp.637-644
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• 2008

감성을 인식하고 반응하는 감성컴퓨터를 개발하기 위한 감성인식에 대한 연구가 활발하다. 본 연구는 2차원으로 정의한 감성을 측정하기 위해서 시간에 따른 생리신호의 반응 변수를 정의하고 그 변수로 인한 감성을 구분하고자 하였다. 10명의 대학생에게 16장의 감성을 유발시킬 수 있는 이미지를 제시하였다. 그리고 자율신경계 반응으로 ECG(electrocardiogram), PPG(photoplethysmogram), GSR(Galvanic skin response), RSP (respiration), 그리고 SKT(skin temperature)를 측정하였다. 본 연구는 자율신경계 반응에 대해 Delay, Activation, Half recovery 그리고 Full recovery로 이루어진 TDP(Time Dependent Parameters)를 정의하고 감성을 구분할 수 있는지에 대한 통계적 유의성을 검증하였다. 그 결과, TDP가 감성을 구분할 수 있는 유의미한 변수로 확인하였고 특징적 경향을 보임을 알 수 있었다. 그러므로 본 연구는 TDP가 감성 인식을 위한 유효한 변수일 가능성을 보였다.

• 설비공학논문집
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• 제8권4호
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• pp.463-472
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• 1996

Experiments were carried out to study the operation characteristics of a regenerator with a thermo-syphon pump and a surface-flame burner for a lithium bromide (LiBr)-water absorption heat pump. A cylindrical-shape metal-fiber burner and commercial grade propane were used. The emission of carbon monoxide and nitric oxide was measured by a combustion gas analyzer. Ther regeneration rate of water vapor as a refrigerant was measured. It could be as a reference value showing the performance of the regenerator. The circulation rate of the LiBr-water solution was also measured from both the tanks for the weak-and the strong-solution. Using a refractometer, the LiBr concetration in the solution was calculated from the measured refractory index of the solution. Temperature of the solution and the condensed water was recorded at several points in the experimental apparatus with thermocouples, using a personal computer. This data collecting system for measuring temperature was calibrated with a set of standard thermometers. The generating rate of water vapor as refrigerant increased linearly with heat supplied. It was about 4.0g/s with the heat supplied at a rate of 16,500kcal/h. The circulation rate of LiBr solution also increases with the heat supplied. The difference in LiBr concentrations between the weak and the strong solution was in the range of 1 to 5% when the concentration of the strong solution was about 60%. It was dependent upon both the heat supplied and the circulation rate of the solution. The initial concentration and the level of the LiBr solution in the regenerator were measured and recorded before experiments. The effect of them on the generating rate of water vapor and the circulation rate of the solution was also studied. The generating rate of water vapor was not strongly dependent upon both the level of the LiBr solution and the initial LiBr concentration. However, the concentration difference of the solution increases with the initial level of the LiBr solution.