• Title/Summary/Keyword: Rate Sensitivity

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A Field Trial as Dry-cow Therapy Using Nophazin (norfloxacin mixed cephalexin) in Mastitis Control (건유기 유방염 치료제 Nophazin리 야외응용시험)

  • 손봉환;황현순;김종훈;최진영
    • Korean Journal of Veterinary Service
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    • v.13 no.2
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    • pp.130-140
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    • 1990
  • A field test using Nophazin (drying off period therapeutics) was done from May, 1989 to October, 1989. 299 quarters of 75 cows from 28 herds were tested. The results were summarized as follows. 1. At the day 7 after parturition, CMT-was 81.60%, clots were removed perfectly, removal rate of hard, hot, pain was 99.6%, only one hard 0.35% was maintained. Recovery rate of general symptoms was 100%. 2. Recovery rate in Nophazin treatment was 100% in Micro-coccus SPP, Corynebacterium SPP, and unisolated, 97.06% in Enterobacterid SPP, 95.58% in Staphylococcus SPP, 91.67% in other Bacilli, 89.19% in Streptococcus SPP, Overall recovery rate was 95.32%, And fungi did not react. 3. The ratio of isolated microorganisms was Staphylococcus SPP 49.8%, Streptococcus SPP 16.3%, Enterobacteria SPP 15.0%, Micrococcus SPP 7.9% Corynebacterium SPP 4.4%, Pseudomonas SPP 2.6%, Bacilli 2.6% and Fungi 1.3%. 4. The range of sensitivity of each microorganism to therapeutics is as follow : Staphylococcus SPP 61.1∼94.7%, Streptococcus SPP 51.4∼91.9%, Micrococcus SPP 44.4∼94.4%, Corynebacterium SPP 70∼80%, Enterobacteria SPP 11.8∼88.2%, and other Gram negative bacilli 8.3∼83.3%. Overall sensitivity was in the range of 50.4∼92.0%, Microorganisms showed the highest sensitivity (80∼94.7%) to Nophazin. 5. New intramammary infection rate was 3.96% (9 strains) at paturition, 8.37% (19 strains) at the day 7 after paturition. Persistent organism wits 6.17% .(14 strains). 6. There was no side effect of Nophazin treatment.

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Expression of MAGE A 1-6 and SSX 1-9 Genes in the Sputum and Cancer Tissue of the Lung Cancer Patients (폐암환자의 객담 및 암 조직에서 MAGE A 1-6와 SSX 1-9 유전자의 발현)

  • Lee, Yeun-Jae;Lee, Jang-Hoon;Lee, Jung-Cheul;Lee, Kwan-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.70 no.4
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    • pp.315-322
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    • 2011
  • Background: A variety of diagnostic modalities for lung cancer have been developed. To achieve efficient and early detection of lung cancer, we tried to measure the expression rates of the melanoma associated gene (MAGE) and synovial sarcoma on X chromosome (SSX) genes. Methods: We designed primers for the SSX gene. In addition to the pre-developed MAGE A primer, using an SSX gene primer was attempted to increase the detection rate. We obtained cancer tissues and cancer-free lung tissues from resected lung, sputum from lung cancer patients who had not undergone surgery, and sputum from healthy people and patients with benign intrathoracic diseases. Results: The sensitivity of the MAGE or SSX gene RT-PCR to identifying cancer tissue of the 69 lung cancer patients was 95.2% for squamous cell carcinoma (scc), 87.0% for adenocarcinoma, and 100% for small cell carcinoma. The mean sensitivity value was 94.2% (p=0.001). For adenocarcinoma, the additional use of the SSX gene resulted in a higher expression rate than MAGE alone (87% vs. 69.6%). The expression rate for the cancer-free lung tissue was 14.3% in scc, 17.4% in adenocarcinoma, and 25.0% in small cell carcinoma. In the induced sputum of 49 lung cancer patients who had not undergone surgery, the expression rate for one of the two genes was 65.5%. The expression rate for the sputum of healthy people and benign intrathoracic diseases by MAGE or SSX gene reverse transcription polymerase chain reaction (RT-PCR) was 3.8% and 17.7%. Conclusion: Detecting lung cancer using the expression of MAGE and SSX genes in lung cancer tissue has high sensitivity.

Evaluation of Tank Capacity of Rainwater Harvesting System to Secure Economic Feasibility and Sensitivity Analysis (경제성 확보를 위한 빗물이용시설의 규모 산정 및 민감도 분석)

  • Mun, Jung-Soo;Kim, Ha-Na;Park, Jong-Bin;Lee, Jung-Hun;Kim, Ree-Ho
    • Journal of Korean Society of Water and Wastewater
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    • v.26 no.2
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    • pp.191-199
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    • 2012
  • Rainwater harvesting systems (RWHS), one of measures for on site rainwater management, have been promoted by laws, regulations and guidelines and have been increased. However, more evaluation of economic feasibility on RWHS is still needed due to seasonal imbalance of rainfall and little experiences and analysis on design and operation of RWHS. In this study, we investigated tank capacity of RWHS to secure economic validity considering catchment area and water demand, which is affected by building scale. Moreover, sensitivity analysis was performed to examine the effect of design factors, cost items and increase rate of water service charge on economic feasibility. The BCR (benefit cost ratio) is proportional to the increase in tank capacity. It is increased steeply in small tank capacity due to the effect of cost and, since then, gently in middle and large tank capacity. In case of 0.05 in the rate of tank volume to catchment area and 0.005 in water demand to catchment area, BCR was over one from the tank capacity of 160 $m^{3}$ taking into account of private benefits and from the tank capacity of 100 $m^{3}$ taking into account of private and public benefits. Sensitivity analysis shows that increase of water demand can improve BCR values with little cost so that it is needed to extend application of rainwater use and select a proper range of design factor. Decrease of construction and maintenance cost reduced the tank volume to secure economic validity. Finally, increase rate of water service charge had considerable impact on economic feasibility.

Sensitivity Variations with pre-irradiation dose to P-type Semi conductor for radiation dosimetry

  • 최태진;김옥배
    • Progress in Medical Physics
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    • v.6 no.1
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    • pp.49-57
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    • 1995
  • The semiconductor detector has a high sensitive to radiation and a small volume. It has been frequently used in high energy photon and electron beamdosimetry. However, Semiconductor detector are subject to radiation damage in high energy radiation beam which reduces the sensitivity and creat a large discrepancy. In this experiments, P-type semiconductor was irradiated to 18 MeV electron beam with pre-irradiation for reducing the sensitivity for high reproducibility and investigated the dose characteristics against the dose rate variations. The sensitivity per unit dose in small dose rate showed a 35% large different to a large dose rate with pre-irradiation dose for 0.5 KGy and 20% for 3 KGyin this study. The silicon detector has showed a large dependency of beam direction with 13% discrepancy and a linear sensitive as increased temperature.

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A Study on the Digital Mammography for Breast Cancer Patients (유방암 환자의 Digital Mammography에 관한 연구)

  • Lim, Cheong-Hwan;Lee, Sang-Ho;Jung, Hong-Ryang;Mo, Eun-Hui
    • Journal of the Korean Society of Radiology
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    • v.6 no.1
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    • pp.63-71
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    • 2012
  • This study aimed to evaluate the accuracy of breast cancer diagnosis of digital mammography which is in the highest interest of breast imaging test, and to investigate the characteristics of breast cancer patients. For this purpose, 57 breast cancer patients who underwent breast imaging test were examined between May 2010 and June 2011. The average age of the breast cancer patients was 50.8 years old, and the most frequently occurring location was the upper outer quadrant (UOQ), accounting for 33.3%. By age, the highest occurrence rate of breast cancer was the age group of 40~49, accounting for 42.1%. As for the breast composition of the breast cancer patients, fatty breast accounted for 31.6% (18/57) and dense breast for 68.4% (39/57), indicating that nearly 70% of the breast cancer patients have dense breast. It was found that the detection rate of breast cancer was the highest (45.3%) when both microcalcification and mass are simultaneously present in the radiographic lesion of the breast imaging. In dense breast, the mass without microcalcification was lower in detection rate than fatty breast. Accordingly, the mass is the cause of raising the false negative rate in dense breast. The findings show that the false negative rate of digital mammography was 7.0% and the sensitivity 93.0%. Also, the false negative rate of dense breast was 12.8%, and the sensitivity 87.2%, indicating that the sensitivity to breast cancer in this study was higher than the dense breast of previously reported screen film mammography.

Analysis of the dynamic characteristics for the change of design parameters of an underwater vehicle using sensitivity analysis

  • Jeon, Myungjun;Yoon, Hyeon Kyu;Hwang, Junho;Cho, Hyeon Jin
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.10 no.4
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    • pp.508-519
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    • 2018
  • In order to design the hull form of an underwater vehicle in the conceptual design phase, the dynamic characteristics depending on the hull form parameters should be identified. Course-keeping stability, turning ability, yaw-checking ability, and mission competence are set to be the indices of the dynamic characteristics, and the geometric parameters for the bare hull and rudder are set to be the hull form design parameters. The total sensitivity of the dynamic characteristics with respect to the hull form parameters is calculated by the chain rule of the partial sensitivity of the dynamic characteristics with respect to the hydrodynamic coefficients, and the partial sensitivity of the hydrodynamic coefficients with respect to the hull form parameters. Based on the sensitivity analysis, important hull form parameters are selected, and those optimal values to satisfy the required intercept time of mission competence of a specific underwater vehicle and turning rate are estimated.

Application of sensitivity analyses in premixed combustion within a porous ceramic burner (다공 세라믹 연소기 속에서의 예혼합연소에 대한 민감도 해석의 적용)

  • Im, In-Gwon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.22 no.2
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    • pp.162-172
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    • 1998
  • A numerical study of premixed combustion within a porous ceramic burner (PCB) is performed to understand flame behavior with respect to various model parameters. Basic flame structure within the porous ceramic burner and species profiles such as NO and CO are examined. Sensitivity analysis of flame speed, gas and solid temperature, NO and CO emission from the burner with respect to reaction steps and various physical properties of the ceramic material is applied to find the most significant parameters in selection of porous materials for the porous ceramic burner. Effects of thermal conductivity, extinction coefficient and scattering albedo on the burner characteristics are studied through the sensitivity analysis. The results of sensitivity study reveal the order of importance in ceramic material properties to get suitable burner performance. Scattering albedo, which governs the ratio of absorbed energy by the ceramic material to total radiative energy transferred, is one of the most important parameters in the material properties since it affects the actual absorbed radiation rate and thus it largely affects the flame structure. Through the study, it is found that the sensitivity study can be used to estimate the flame behavior within the porous ceramic burner more effectively.

Evaluation of Bit Error Rate of a Long-Haul Optical Transmission System adopted the Mid-Span Spectral Inversion Method (Mid-Span Spectral Inversion 기법을 채택한 장거리 광 전송 시스템에서의 비트 에러율 평가)

  • Lee, Seong-Real;Kim, Nam-Sung;Bang, Hyo-Chang
    • Journal of Advanced Navigation Technology
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    • v.6 no.3
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    • pp.223-230
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    • 2002
  • In this paper, we induced that the noise powers and bit error rate of direct detection receiver taking account of ISI (intersymbol interference) in the 2,000 km optical transmission system. And we evaluated the sensitivity in the vrious bit rate system. We verified that the proposed calculation method is applicable to the exact optical system. And we confirmed that the signal distortion due to both chromatic dispersion and nonlinear effects compensated by using of MSSI (Mid-Span Spectral Inversion) method, and yet the sensitivity of a higher bit rate system is reduced, because of the increase of ISI and then the decrease of the average receiving power, compared with a the lower bit rate system.

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Evaluation of Contribution Rate of PM Concentrations for Regional Emission Inventories in Korean Peninsula Using Brute-force Sensitivity Analysis (Brute-force 방법을 이용한 한반도 미세먼지 농도에 대한 배출원의 기여도 산출 연구)

  • Lee, Soon-Hwan;Lee, Kang-Yeol
    • Journal of Environmental Science International
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    • v.24 no.11
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    • pp.1525-1540
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    • 2015
  • In order to clarify the contribution rate of PM concentration due to regional emission distribution, Brute force analysis were carried out using numerical estimated PM data from WRF-CMAQ. The emission from Kyeongki region including Seoul metropolitan is the largest contribution of PM concentration than that from other regions except for emission of trans-country and source itself. Contribution rate of self emission is also the largest at Kyeongki region and its rate reach on over 95 %. And the rate at Gangwon region also higher than any region due to synoptic wind pattern. Due to synoptic wind direction at high PM episode, pollutants at downwind area along from west to east and from north to south tends to mix intensively and its composition is also complicated. Although the uncertainty of initial concentration of PM, the contribution of regional PM concentration tend to depend on the meteorological condition including intensity of synoptic and mesoscale wind and PM emission pattern over upwind region.

Analyzing an Economic Feasibility for Restoration/Creation of Artificial Tidal Flats (인공갯벌 조성에 관한 경제적 타당성 분석)

  • Nam, Kwang-Hyun;Oh, Wee-Yeong
    • Ocean and Polar Research
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    • v.25 no.4
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    • pp.593-601
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    • 2003
  • The purpose of this paper is to investigate economic feasibility of creating artificial tidal flats using cost-benefit analyses. We assumed that the cost factors are associated with designing, construction and monitoring, and the benefit factors are associated with fisheries production, habitation, prevention of disasters, water purification, aesthetic value and existence value. First, for analyzing economic feasibility, the scenario suggests that a design can be made in a year, construction can be completed in three years and monitoring must be made for 20 years. Assuming the discount rate of 7.5%, economic feasibility analyses showed that B/C was 2.26 and IRR was 14.50. This study indicated there is economic validity of implementing creation of artificial tidal flat. In addition, we carried out a sensitivity analysis at the change of discount rate and restoration rate. The result of sensitivity analysis clearly showed that economic validity is low when discount rate is over 15%, and changes in restoration rate did not significantly effect on the economic validity.