• 생명과학회지
• /
• 제28권12호
• /
• pp.1545-1553
• /
• 2018

희소당(Rare Sugars)은 국제희소당학회(International Society of Rare Sugars, ISRS)에 의해 지구상에 극히 소량 존재하는 단당류 또는 단당 유도체로서 정의되어 있으며, 희소당이 보유하고 있는 저칼로리, 항암, 항염증 및 항산화와 같은 유용한 생리활성으로 인해 현대산업분야에서 높은 주목을 받고 있는 차세대 기능성 신소재이다. 희소당은 자연계에 존재의 희소성으로 인해 희소당의 원활한 공급을 위한 희소당 생산 연구는 무엇보다도 중요한 연구로서 인식되어져 있다. 일반적으로 희소당은 화학적 방법과 미생물 유래 효소를 이용한 생물학적 방법으로 생산이 가능한데, 친환경적이며 생산공정도 안전한 생물학적 방법이 최근에 많은 주목을 받고 있다. 현재까지 희소당은 약 50종류 이상이 보고되어져 있는데 저칼로리, 항산화, 설탕 유사 감도 및 감미 특성으로부터 D-Allulose, D-Allose, 그리고 D-Tagatose가 특히 많은 주목을 받고 있는 희소당으로서 알려져 있다. 본 연구에서는 식품산업 및 의약산업을 비롯하여 다양한 산업분야에서 향 후 높은 활용성이 기대되는 D-Allulose, D-Allose, 그리고 D-Tagatose에 대한 미생물 유래 효소를 이용한 생물전환 생산에 대하여 보고를 하고자 한다.

• 자원리싸이클링
• /
• 제29권6호
• /
• pp.3-14
• /
• 2020

석탄재로부터 희토류 회수에 관한 연구 자료를 분석 및 검토하였다. 석탄재로부터 희토류 회수를 위해 적용된 선별 실험은 주로 PC 보일러로부터 발생된 석탄재를 대상으로 입도분리, 자력, 비중 및 부유선별법 등을 이용해 연구하였다. 선별 공정을 통해 희토류 성분의 농축 가능한 수준은 수 천 ppm 정도로 낮게 확인되었고, 선별 공정 이후 회수된 산물을 대상으로 습식 제련 공정을 통한 추가 농축 처리가 필요한 것으로 확인되었다. 침출 공정에서는 석탄재의 희토류 성분을 침출 향상을 위해 알칼리 용융과 같은 전처리 후, 침출공정에 적용하는 것이 효율적인 공정으로 확인되었다. 세계적 희토류 회수 시스템의 개발이 아직은 미흡한 것으로 확인되었으나, 석탄재에 포함된 희토류 회수 연구는 계속 진행될 것으로 보고되었다. 국내에서는 석탄재 중 희토류 회수를 위한 회수 기술이 매우 부족한 상황으로 선별, 침출 등의 기술 개발이 시급한 실정이다.

• 대한화학회지
• /
• 제29권2호
• /
• pp.183-190
• /
• 1985

이온교환수지로 희토류원소들을 분리 하기 위해 용리액으로 iminodiacetic acid(IMDA)를 사용하였다. 용리액의 pH변화에 따른 음이온교환수지와 양이온교환수지에서 희토류원소들의 IMDA 화학종변화와 이들의 분리조건을 밝히고저 하였다. 희토류원소들의 가장 좋은 분리조건은 양이온교환수지에서 0.0301M IMDA의 pH를 8.00에서 9.00까지 단계적으로 변화시키면서 용리시켰을 때였고 용출순서는 원자번호순서와 일치하였다. 용리액의 pH변화에 따른 희토류원소와 IMDA간의 화학종 변화를 용리곡선과 자외선 흡수 스펙트럼으로 부터 추정하였다.

• 한국안전학회지
• /
• 제30권1호
• /
• pp.87-93
• /
• 2015

Most incidents and accidents involved human during operating NPPs have a tendency to be structured by complicated and various organizational, individual, and environmental factors. The salient feature of the human error in NPP was extremely low frequency, extremely high complicated and extremely serious damage of human life and property. Our research team defined as 'rare human errors'. To prevent the rare human errors, the most researchers and analysts insist invariably that the root causes be made clear. The making them clear, however, is difficult because their root causes are very various and uncertain. However, These tools have limits that they do not adapt all operating situations and circumstances such as design base events. The purpose of this study is to improve the rare human error hazards consider the situational contex. Through this challenging try based on evidences to the human errors could be useful to prevent rare and critical events can occur in the future.

• 한국분말재료학회지
• /
• 제22권1호
• /
• pp.27-31
• /
• 2015

Flat panel display devices are mainly used as information display devices in the 21st century. The worldwide waste flat panel displays are expected at 2-3 million units but most of them are land-filled for want of a proper recycling technology More specifically, rare earth metals of La and Eu are used as fluorescent materials of Cold Cathode Flourscent Lamp(CCFL)s in the waste flat panel displays and they are critically vulnerable and irreplaceable strategic mineral resources. At present, most of the waste CCFLs are disposed of by land-filling and incineration and proper recovery of 80-plus tons per annum of the rare earth fluorescent materials will significantly contribute to steady supply of them. A dearth of Korean domestic research results on recovery and recycling of rare earth elements in the CCFLs prompts to initiate this status report on overseas research trends and noteworthy research results in related fields.

• Genomics & Informatics
• /
• 제18권2호
• /
• pp.17.1-17.4
• /
• 2020

The amount of content on social media platforms such as Twitter is expanding rapidly. Simultaneously, the lack of patient information seriously hinders the diagnosis and treatment of rare/intractable diseases. However, these patient communities are especially active on social media. Data from social media could serve as a source of patient-centric knowledge for these diseases complementary to the information collected in clinical settings and patient registries, and may also have potential for research use. To explore this question, we attempted to extract patient-centric knowledge from social media as a task for the 3-day Biomedical Linked Annotation Hackathon 6 (BLAH6). We selected amyotrophic lateral sclerosis and multiple sclerosis as use cases of rare and intractable diseases, respectively, and we extracted patient histories related to these health conditions from Twitter. Four diagnosed patients for each disease were selected. From the user timelines of these eight patients, we extracted tweets that might be related to health conditions. Based on our experiment, we show that our approach has considerable potential, although we identified problems that should be addressed in future attempts to mine information about rare/intractable diseases from Twitter.

• 한국방사성폐기물학회:학술대회논문집
• /
• 한국방사성폐기물학회 2004년도 학술논문집
• /
• pp.337-337
• /
• 2004

As one of researches for the P ＆ T purposes, a basic experiment on the recovery of actinide elements from the mixture with rare earth elements by means of electrorefining using a liquid cadmium cathode in the LiCl-KC1 eutectic melt was carried out. In order to examine the behaviors of electrodeposition of metal ions on a liquid electrode, recovery experiments of rare earth metals resulting from forming electrodeposits were performed by a galvanostatic electrolysis method at various current densities. A cyclic voltammetric technique was applied to determine reduction-oxidation potential of each metal element in the melt and to detect the changes of the multi component melt composition for on-line monitoring. Also, a collaboration study with RIAR was completed to test the preliminary feasibility on a recovery of actinide elements from the mixture with rare earth elements using a liquid cadmium cathode and actinide metals. Experimental results showed that the ratio of actinides to rare earths, 9: 0.5∼1 led to the rare earth content of about 5∼10 wt% in the deposit.

• BMB Reports
• /
• 제43권10호
• /
• pp.698-703
• /
• 2010

In this study, we characterized two blocks of minisatellites in the 5' upstream region of the BORIS gene (BORIS-MS1, -MS2). BORIS-MS2 was found to be polymorphic; therefore, this locus could be useful as a marker for DNA fingerprinting. We assessed the association between BORIS-MS2 and breast cancer by a case-control study with 428 controls and 793 breast cancers cases. Rare alleles in the younger group (age, <40) were associated with a statistically significant increased risk of breast cancer (odds ratio, 4.84; 95% confidence interval, 1.06-22.22; and P = 0.026). A statistically significant association between the short rare alleles and cancer was identified in the younger group (8.02; 1.01-63.83; P = 0.021). Kaplan-Meier estimates showed that poor prognosis was associated with patients who contained the rare alleles. Our data suggest that the short rare alleles of BORIS-MS2 could be used to identify the risk for breast cancer in young patients.

• 임상간호연구
• /
• 제14권3호
• /
• pp.153-163
• /
• 2008

Purpose: The purpose of this research, using descriptive correlation design was to identify the extent to which the mothers having children with rare genetic metabolic diseases(MPS, PWS) have parenting stress and guilt feeling. Method: This study used PSI /SF(Abidin, 1995) and Guilt Index as devised herein. From 156 mothers, data were collected from February to July 2006, using self-administered questionnaires. This study received the approval from IRB at S Hospital (IRB File No: 2006-02-014). Data were analyzed with descriptive statistics, t-test, ANOVA, and correlation. Results: Mothers felt very high level of parenting stress and sense of guilt. Parenting stress was related positively to guilt feeling. Conclusion: These findings could help understand the families of children with rare genetic metabolic diseases and those provide basic information in developing effective counseling and education programs for relief of parenting stress and guilt feeling. This study would be significant in the fact that it is the first research, targeting on the families of children with rare genetic metabolic diseases in Korea.

• Korean Chemical Engineering Research
• /
• 제55권3호
• /
• pp.379-384
• /
• 2017

LiCl 용융염에서 희토류 산화물의환원율을 높이기 위해 NiO와 혼합하여 전해환원을실시하였다. Cyclic voltammetry (CV) 실험을 통해 LiCl 용융염 내에서 혼합산화물의 전기화학적 환원거동을 조사하였다. 혼합산화물로 제작된 환원전극과 그라파이트 산화전극 사이에 일정한 작동전압을 인가하여 이론전하량 대비 다양한 전하량을 공급한 후 중간생성물의 결정구조를 XRD를 이용하여 분석하였다. NiO 산화물을 첨가함으로써 전기전도성이 좋은 Ni 금속 주위로 희토류 산화물이 환원되어 RE-Ni 합금형태의 금속으로 완전히 전환되었으며, 합금을 형성하는 반응 메커니즘을 제시하였다.