• Title/Summary/Keyword: Rapid Assessment Method

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Assessment of DNA damage and Chromosome aberration in human lymphocyte exposed to low dose radiation detected by FISH(fluorescence in situ hybridization) and SCGE(single cell gel electrophoresis) (FISH기법 및 단세포전기영동기법을 이용한 저선량 방사선에 의한 DNA 상해 및 염색체이상 평가)

  • Chung, Hai-Won;Kim, Su-Young;Kim, Byung-Mo;Kim, Sun-Jin;Kim, Tae-Hwan;Cho, Chul-Koo;Ha, Sung-Whan
    • Journal of Radiation Protection and Research
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    • v.25 no.4
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    • pp.223-232
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    • 2000
  • Comparative study was performed for the assessment of DNA damage and Chromosomal aberration in human lymphocyte exposed to low dose radiation using fluorescence in situ hybridization(FISH) and single cell gel electrophoresis(SCGE). Chromosomal aberrations in human lymphocytes exposed to radiation at doses of 5, 10, 30 and 50cGy were analysed with whole chromosome-specific probes by human chromosome 1, 2 and 4 according to PAINT system. FISH with chromosome-specific probe has been used to be a valid and rapid method fer detection of chromosome rearrangements induced by low dose radiation. The frequencies of stable translocation per cell equivalents were 0.0116, 0.0375, 0.040f, 0.0727 and 0.0814 for 0, 5, 10, 30 and 50cGy, respectively, and those of dicentric were 0.00, 0.0125, 0.174, 0.0291 and 0.0407 respectively. Radiation induced DNA damage in human lymphocyte in a dose-dependent manner at low doses from 5cGy to 50cGy, which were analysed by single tell gel electrophoresis(SCGE). From above results, FISH seemed to be useful for radiation biodosimetry by which the frequencies of stable aberrations in human lymphocyte can be observed more easily than by conventional method and SCGE also seemed to be sensitive method f9r detecting DNA damage by low dose radiation exposure, so that those methods will improve our technique to perform meaningful biodosimetry for radiation at low doses.

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Wetland Function Evaluation and Expert Assessment of Organic Rice-Fish Mixed Farming System (유기농 벼-담수어 복합영농의 습지기능평가 및 전문가 조사)

  • Nam, Hongsik;Park, Kwanglai;An, Nanhee;Lee, Sangmin;Cho, Junglai;Kim, Bongrae;Lim, Jongahk;Lee, Changwon;Choi, Seonu;Kim, Changhyun;Kong, Minjae;Son, Jinkwan
    • Journal of Wetlands Research
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    • v.20 no.2
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    • pp.161-172
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    • 2018
  • A mixed farming system that includes organic rice production and freshwater fish farming is being called into attention in Korean agricultural industry and rural areas in order to improve farm management and environmental conservation. This study was conducted to evaluate the environmental and ecological value of such mixed farming practices. Expert assessment and rapid assessment method (RAM) of wetland evaluation were employed for this study. Experts have responded that biodiversity conservation including amphibian and reptile habitat (2.39), aquatic insect habitat (2.36), Fishery habitat (2.34), vegetation diversity (2.13), avian habitat (2.05), and experience and education were the most important function of mixed farming. The wetland function evaluation conducted using modified RAM indicated that rice-fish mixed system showed improvements in most of the evaluated functions, compared to the conventional rice paddies. The overall wetland function of rice paddies in rice-fish mixed system was greatly improved as compared with the conventional rice paddies. Rice paddies are known to play an important role in biodiversity maintenance, and provide ecosystem services such as climate modulation and carbon reduction. Rice-fish mixed system of farming may not only improve various ecosystem services of rice paddies, but may increase farm income through value added fish farming, as well as promotion of social services such as education and maintenance of tradition. Additional research is needed for quantitative analysis of the values gained from the most improved wetland function when mixed farming system is actually put into practice, and to utilize the results in advertising of the organic rice, and in various sectors such as food, education and direct payment policy.

Development of Estimation Models for Parking Units -Focused on Gwangju Metropolitan City Condominium Apartments- (주차원단위 산정 모형 개발에 관한 연구 -광주광역시 공동 주택 아파트를 대상으로-)

  • Kwon, Sung-Dae;Ko, Dong-Bong;Park, Je-Jin;Ha, Tae-Jun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.34 no.2
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    • pp.549-559
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    • 2014
  • The rapid expansion of cities led to the shortage of housing in urban areas. The government compensated for this shortage through large scale residential developments that increased the housing supply. The supply of condominium apartments remains above 83% of the entire housing supply, and the proportion of apartments are at a steady increase, at about 50%. Due to the increase, illegally parked cars resulting from the shortage of parking spaces within the apartment complex have become increasingly problematic as they block the transit of emergency vehicles, and heighten the tension among neighboring residents in obtaining a parking space. Especially, the future residents are considered to plan the parking based on the estimated demand for parking. However, the parking unit method utilized to estimate the parking demand accounts for the exclusive use of space, which is believed to be far from the parking demands in reality. The reason for this discrepancy is that, as the number of households decrease, and area of exclusive space is expanded, the planned parking increases. On the other hand, when the number of households increase, and the area of exclusive space is reduced, the planned parking decreases, thus methods to recalculate the parking units based on estimated parking demand is an urgent concern. To estimate the parking units based on condominium apartments, this study first examined the existing research literature, and appointed the field of investigation to collect the necessary data. In addition, field study data and surveys collected and analyzed, in order to identify the problems underlying parking units, and problems regarding the current traffic impact assessment parking unit calculation method were deduced. Through identifying the influential factors on parking demand estimates, and performing a factorial analysis based on the collected data, the variables were selected in relation to the parking demand estimates, to develop the parking unit estimate model. Finally, through comparing and verifying the existing traffic impact assessment parking unit estimate against the newly developed model using collected data, a far more realistic parking unite estimate was suggested, reflecting the characteristics of the residents. The parking unit estimate model developed in this study is anticipated to serve as the guidelines for future parking lot legislature, as wel as the basis to provide a more realistic estimate of parking demands based on the resident characteristics of an apartment complex.

Suitability Assessment of Domestic Natural Waters as a Culture Medium for Daphnia magna (Daphnia magna의 배양배지로서 국내 자연수의 적절성 평가)

  • Yeom, Dong-Hyuk;Jeon, Chan-Sig
    • Korean Journal of Ecology and Environment
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    • v.45 no.3
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    • pp.271-277
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    • 2012
  • The present study was conducted to assess the suitability of domestic natural waters as a Daphnia magna culture medium. In order to assess survival rate and reproductive output, young female daphnids (parent animals), aged less than 24 hours at the start of the test and produced in the Elendt M4 medium, were exposed to Elendt M4 medium, de-chlorinated tap water, and natural mineral water for 21 days. D. magna cultured in Elendt M4 medium (reference medium) and natural mineral water met the criteria of OECD No. 211, Daphnia magna Reproduction Test Guidelines in terms of percent adult survival, first day of reproduction, and average young production. However, the mortalities of adult daphnids observed in de-chlorinated tap water were more than 20% in two reproduction tests for 21 days. Mortality was observed on exposure days 13, 15, and 18 in de-chlorinated water. The use of D. magna is recommended in water of hardness >80 mg $CaCO_3\;L^{-1}$. However, the hardness of de-chlorinated tap water used in the present study was 50~53 mg $CaCO_3\;L^{-1}$. Therefore, it is judged that the delayed mortalities observed in de-chlorinated tap water were caused by a rapid decreased in hardness when the medium was changed from Elendt M4 to de-chlorinated tap water. When D. magna is cultured using domestic natural waters (underground water, surface water, and de-chlorinated water), the quality-control (QC) data should be maintained through a standardization for health assessment method, toxicity test method using reference chemical, test intervals of reference toxicant toxicity test, and data treatment and interpretation. In the long term, national research programs are needed for the development of test species which are representative of domestic aquatic environmental conditions among indigenous daphnids.

Effect of Passing Aged Years and Coating Thickness on Corrosion Properties of Reinforcing Steel in Mortar (W/C:0.5) (모르타르(W/C:0.5)내의 철근의 부식 특성에 미치는 재령 년수와 피복두께의 영향)

  • Moon, Kyung-Man;Lee, Sung-Yul;Jeong, Jin-A;Lee, Myeong-Hoon;Baek, Tae-Sil
    • Corrosion Science and Technology
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    • v.14 no.2
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    • pp.99-105
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    • 2015
  • The structures of reinforced concrete have been extensively increased with rapid development of industrial society. Futhermore, these reinforced concretes are easy to expose to severe corrosive environments such as seawater, contaminated water, acid rain and seashore etc.. Thus, corrosion problem of steel bar embedded in concrete is very important in terms of safety and economical point of view. In this study, specimens having six different coating thickness (W/C:0.5) were prepared and immersed in flowing seawater for five years to evaluate the effect of coating thickness and immersion time on corrosion property. The polarization characteristics of these embedded steel bars were investigated using electrochemical methods such as corrosion potential, anodic polarization curve, and impedance. At the 20-day immersion, the corrosion potentials exhibited increasingly nobler values with coating thickness. However, after 5-yr. immersion their values were shifted in the negative direction, and the relationship between corrosion potential and coating thickness was not shown. Although 5-yr. immersion lowered corrosion potential, 5-yr. immersion did not increase corrosion rate. In addition, after 5-yr. immersion, the thinner cover thickness, corrosion current density was decreased with thinning coating thickness. It is due to the fact that ease incorporation of water, dissolved oxygen and chloride ion into a steel surface caused corrosion and hence, leaded to the formation of corrosion product. The corrosion product plays the role as a corrosion barrier and increases polarization resistance. The corrosion probability evaluated depending on corrosion potential may not be a good method for predicting corrosion probability. Hence, the parameters including cover thickness and passed aged years as well as corrosion potential is suggested to be considered for better assessment of corrosion probability of reinforced steel exposed to partially or fully in marine environment for long years.

A Study on the Course Certification System of Library and Information Science and Similar Disciplines (문헌정보학 및 유사분야의 교육과정인증시스템 분석연구)

  • Noh, Younghee
    • Journal of Korean Library and Information Science Society
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    • v.47 no.2
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    • pp.71-98
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    • 2016
  • Librarian certification in Korea is issued by the LIS Departments, the Academy of Librarianship, and the Academic Credit Bank system; however, it has been pointed out that there is a limit to how much these nurture high quality librarians, because the education quality and contents varies from education institutions and there is no verification method for certification issued by educational programs. Therefore, this study investigated certification systems of academic or training programs that are conducted at home and abroad, analyzed how the certification systems are oriented, what the purpose and criteria of the certification systems are, and what the content of assessment is. As a result of this investigation, several areas needing change were identified which if adopted can improve the system. These included making amendments to the library laws related to the certification system, substantially revising the relevant enforcement ordinance, making changes to the selection of the Certification authority, establishing certification standards and procedures, developing contents related to document examination and due diligence audits, rating the effects of the certification system, and setting standards. Improving the Librarian Certification System has been discussed over the past 20 years and should not be delayed any longer because of the university structural reform of the current government, the rapid rise of the qualified librarians, decreasing employment due to the human resources supply and demand imbalances, all of which has resulted in a survival crisis of four-year Department of Library and Information Science.

Building the Data Mart on Antibiotic Usage for Infection Control (감염관리를 위한 항생제 사용량 데이터마트의 구축)

  • Rheem, Insoo
    • Korean Journal of Clinical Laboratory Science
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    • v.48 no.4
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    • pp.348-354
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    • 2016
  • Data stored in hospital information systems has a great potential to improve adequacy assessment and quality management. Moreover, an establishment of a data warehouse has been known to improve quality management and to offer help to clinicians. This study constructed a data mart that can be used to analyze antibiotic usage as a part of systematic and effective data analysis of infection control information. Metadata was designed by using the XML DTD method after selecting components and evaluation measures for infection control. OLAP-a multidimensional analysis tool-for antibiotic usage analysis was developed by building a data mart through modeling. Experimental data were obtained from data on antibiotic usage at a university hospital in Cheonan area for one month in July of 1997. The major components of infection control metadata were antibiotic resistance information, antibiotic usage information, infection information, laboratory test information, patient information, and infection related costs. Among them, a data mart was constructed by designing a database to apply antibiotic usage information to a star schema. In addition, OLAP was demonstrated by calculating the statistics of antibiotic usage for one month. This study reports the development of a data mart on antibiotic usage for infection control through the implementation of XML and OLAP techniques. Building a conceptual, structured data mart would allow for a rapid delivery and diverse analysis of infection control information.

Internal Dose Assessment of Worker by Radioactive Aerosol Generated During Mechanical Cutting of Radioactive Concrete (원전 방사성 콘크리트 기계적 절단의 방사성 에어로졸에 대한 작업자 내부피폭선량 평가)

  • Park, Jihye;Yang, Wonseok;Chae, Nakkyu;Lee, Minho;Choi, Sungyeol
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.18 no.2
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    • pp.157-167
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    • 2020
  • Removing radioactive concrete is crucial in the decommissioning of nuclear power plants. However, this process generates radioactive aerosols, exposing workers to radiation. Although large amounts of radioactive concrete are generated during decommissioning, studies on the internal exposure of workers to radioactive aerosols generated from the cutting of radioactive concrete are very limited. In this study, therefore, we calculate the internal radiation doses of workers exposed to radioactive aerosols during activities such as drilling and cutting of radioactive concrete, using previous research data. The electrical-mobility-equivalent diameter measured in a previous study was converted to aerodynamic diameter using the Newton-Raphson method. Furthermore, the specific activity of each nuclide in radioactive concrete 10 years after nuclear power plants are shut down was calculated using the ORIGEN code. Eventually, we calculated the committed effective dose for each nuclide using the IMBA software. The maximum effective dose of 152Eu constituted 83.09% of the total dose; moreover, the five highest-ranked elements (152Eu, 154Eu, 60Co, 239Pu, 55Fe) constituted 99.63%. Therefore, we postulate that these major elements could be measured first for rapid radiation exposure management of workers involved in decommissioning of nuclear power plants, even if all radioactive elements in concrete are not considered.

Design and Implementation of Web-based Problem Management System for CT Radiological Technologist Education (CT 전문방사선사 교육을 위한 웹기반 문항관리 시스템의 설계 및 구현)

  • Shin Yong-Won;Koo Bong-Oh;Shim Choon-Bo
    • The Journal of the Korea Contents Association
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    • v.5 no.1
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    • pp.27-35
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    • 2005
  • Recently, despite of the rapid progress of information technology in the medical and health fields, the development and management of problem sets about medical and education contents related with radiological technologist has been still achieved by manual and offline method using document editor. In this study, the unique web-based problem management system is designed and implemented. That system can efficiently manage and present various kind of problem set about integrated education and personal license without time and space limitations in order to improve the efficiency of supplementary training and to obtain the professional license for CT radiological technologist. The proposed system is composed of administration module and user module. The former supports several functions such as problem creation, problem categorization, user management, and adjustment of leveled assessment. On the other hand, the latter functions examination applying , problem retrieval, personal score retrieval, and interpretation viewing, and so on. In addition, our system is expected as a useful and practical system which provides problem interpretation and analysis of score results after applying for the examination. It can elevate ability of learning and information interchange among them preparing for CT professional radiological technologist licensing examination

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A Study of Global Ocean Data Assimilation using VAF (VAF 변분법을 이용한 전구 해양자료 동화 연구)

  • Ahn, Joong-Bae;Yoon, Yong-Hoon;Cho, Eek-Hyun;Oh, He-Ram
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.10 no.1
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    • pp.69-78
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    • 2005
  • ARCO and TAO data which supply three dimensional global ocean information are assimilated to the background field from a general circulation model, MOM3. Using a variational Analysis using Filter (VAF), which is a spatial variational filter designed to reduce computational time and space efficiently and economically, observed ARGO and TAO data are assimilated to the OGCM-generated background sea temperature for the generation of initial condition of the model. For the assessment of the assimilation impact, a comparative experiment has been done by integrating the model from different intial conditions: one from ARGO-, TAO-data assimilated initial condition and the other from background state without assimilation. The assimilated analysis field not only depicts major oceanic features more realistically but also reduces several systematic model bias that appear in every current OGCMs experiments. From the 10-month of model integrations with and without assimilated initial conditions, it is found that the major assimilated characteristics in sea temperature appeared in the initial field remain persistently throughout the integration. Such implies that the assimilated characteristics of the reduced sea temperature bias is to last in the integration without rapid restoration to the non-assimilated OGCM integration state by dispersing mass field in the form of internal gravity waves. From our analysis, it is concluded that the data assimilation method adapted in this study to MOM3 is reasonable and applicable with dynamical consistency. The success in generating initial condition with ARGO and TAO data assimilation has significant implication upon the prediction of the long-term climate and weather using ocean-atmosphere coupled model.