• Nuclear Engineering and Technology
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• v.51 no.3
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• pp.894-903
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• 2019

An approach for collapse risk assessment is proposed to evaluate the vulnerability of electric cabinet in nuclear power plants. The lognormal approaches, namely maximum likelihood estimation and linear regression, are introduced to establish the fragility curves. These two fragility analyses are applied for the numerical models of cabinets considering various boundary conditions, which are expressed by representing restrained and anchored models at the base. The models have been built and verified using the system identification (SI) technique. The fundamental frequency of the electric cabinet is sensitive because of many attached devices. To bypass this complex problem, the average spectral acceleration $S_{\bar{a}}$ in the range of period that cover the first mode period is chosen as an intensity measure on the fragility function. The nonlinear time history analyses for cabinet are conducted using a suite of 40 ground motions. The obtained curves with different approaches are compared, and the variability of risk assessment is evaluated for restrained and anchored models. The fragility curves obtained for anchored model are found to be closer each other, compared to the fragility curves for restrained model. It is also found that the support boundary conditions played a significant role in acceleration response of cabinet.

• Journal of the Korean Association of Geographic Information Studies
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• v.12 no.2
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• pp.120-131
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• 2009

This study measured the centripetal force and effective scope of the population spread from urban center and subcenters in order to diagnose the urban spatial structure of the formation of a multicentric city structure in Busan. The study analyzed the variability of the determination coefficient value (R square) with a negative exponential function derived from the population density model by extending the circular region into 5-km units. The aim of this study was to measure changes in the effective scope of the population centripetal force of the urban center and subcenter in 5-year intervals from 1995 to 2005 using census data. The explanatory adequacy of the population density function was examined with the bias of the function to calculate the distance error between the real location of the urban center and the optimal location, according to the population density function. To summarize the results, the value for the area of Jungangdong showed a continuous reduction, whereas Seomyeon (Bujeondong) maintained explanatory adequacy without a large change. As a whole, Busan was in the process of continuous diversification, in spite of its reduced population. Therefore, it appears necessary to strengthen the function of the urban center and subcenter and to supply adequate dwelling zones close to downtown to form a more efficient urban spatial structure. The results of the present study will be utilized as basic data for the formulation of a political approach to the efficient reorganization of spatial structure by correlating concrete spatial information with the population variability of Busan's urban center and subcenter.

• Journal of Korean Society for Atmospheric Environment
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• v.34 no.1
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• pp.101-119
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• 2018

In this study, we analyzed long-term measurements and air quality simulation results of four criteria air pollutants ($PM_{10}$, $O_3$, $NO_2$, and $SO_2$) for 10 years, from 2006 to 2015, with emphasis on trends of annual variabilities. With the observation data, we conducted spatial interpolation using the Kriging method to estimate spatial distribution of pollutant concentrations. We also performed air quality simulations using the CMAQ model to consider the nonlinearity of the secondary air pollutants such as $O_3$ and the influence of long-range transport. In addition, these simulations are used to deduce the effect of long-term meteorological variations on trends of air quality changes because we fixed the emissions inventory while changing meteorological inputs. The nation-wide inter-annual variability of modeled $PM_{10}$ concentrations was $-0.11{\mu}g/m^3/yr$, while that of observed concentrations was $-0.84{\mu}g/m^3/yr$. For the Seoul Metropolitan Area, the inter-annual variability of observed $PM_{10}$ concentrations was $-1.64{\mu}g/m^3/yr$ that is two times rapid improvement compared to other regions. On the other hand, the inter-annual variability of observed $O_3$ concentrations is 0.62 ppb/yr which is larger than the simulated result of 0.13 ppb/yr. Magnitudes of differences between the modeled and observed inter-annual variabilities indicated that decreasing trend of $PM_{10}$ and increasing trend of $O_3$ are more influenced by emissions and oxidation states than meteorological conditions. We also found similar patterns in $NO_2$. However, $NO_2$ trends showed greater regional and seasonal differences than other pollutants. The analytic approach used in this study can be applicable to estimate changes in factors determining air quality such as emissions, weather, and surrounding conditions over a long term. Then analysis results can be used as important data for air quality management planning and evaluation of the chronic impact of air quality.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.10
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• pp.2073-2081
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• 2002

In product design and manufacturing, axiomatic design provides a systematic approach for the decision-making process. Two axioms have been defined such as the Independence Axiom and the Information Axiom. The Information Axiom states that the best design among those that satisfy the independence axiom is the one with the least information content. In other words, the best design is the one that has the highest probability of success. On the other hand, the Taguchi robust design is used in the two-step process; one is "reduce variability," and the other is "adjust the mean on the target." The two-step can be interpreted as a problem that has two FRs (functional requirements). Therefore, the Taguchi method should be used based on the satisfaction of the Independence Axiom. Common aspects exist between the Taguchi method and Axiomatic Design in that a robust design is induced. However, different characteristics are found as well. The Taguchi method does not have the design range, and the probability of success may not be enough to express robustness. Our purpose is to find the one that has the highest probability of success and the smallest variation. A new index is proposed to satisfy these conditions. The index is defined by multiplication of the robustness weight function and the probability density function. The robustness weight function has the maximum at the target value and zero at the boundary of the design range. The validity of the index is proved through various examples.gh various examples.

• Journal of Korean Society on Water Environment
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• v.23 no.4
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• pp.490-497
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• 2007

A Combined sewer overflows (CSOs) are themselves a significant source of water pollution. Therefore, the control of urban drainage for CSOs reduction and receiving water quality protection is needed. Examples in combined sewer systems include downstream storage facilities that detain runoff during periods of high flow and allow the detained water to be conveyed by an interceptor sewer to a centralized treatment plant during periods of low flow. The design of such facilities as stormwater detention storage is highly dependant on the temporal variability of storage capacity available (which is influenced by the duration of interevent dry periods) as well as the infiltration capacity of soil and recovery of depression storage. As a result, a continuous approach is required to adequately size such facilities. This study for the continuous long-term analysis of urban drainage system used analytical probabilistic model based on derived probability distribution theory. As an alternative to the modeling of urban drainage system for planning or screening level analysis of runoff control alternatives, this model have evolved that offer much ease and flexibility in terms of computation while considering long-term meteorology. This study presented rainfall and runoff characteristics of the subject area using analytical probabilistic model. This study presented the average annual COSs and number of COSs when the interceptor capacity is in the range $3{\times}DWF$ (dry weather flow). Also, calculated the average annual mass of pollutant lost in CSOs using Event Mean Concentration. Finally, this study presented a decision of storage volume for CSOs reduction and water quality protection.

• Proceedings of the Korea Water Resources Association Conference
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• 2005.05b
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• pp.1199-1203
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• 2005

Combined sewer overflows(CSOs) are themselves a significant source of water pollution. Therefore, the control of urban drainage for CSOs reduction and receiving water quality protection is needed. Examples in combined sewer systems include downstream storage facilities that detain runoff during periods of high flow and allow the detained water to be conveyed by an interceptor sewer to a centralized treatment plant during periods of low flow. The design of such facilities as stormwater detention storage is highly dependant on the temporal variability of storage capacity available(which is influenced by the duration of interevent dry periods) as well as the infiltration capacity of soil and recovery of depression storage. As a result, a contiunous approach is required to adequately size such facilities. This study for the continuous long-term analysis of urban dranage system used analytical Probabilistic model based on derived probability distribution theory. As an alternative to the modeling of urban drainage system for planning or screening level analysis of runoff control alternatives, this model have evolved that offer much ease and flexibility in terms of computation while considering long-term meteorology. This study presented rainfall and runoff characteristics or the subject area using analytical Probabilistic model. Runoff characteristics manifasted the unique characteristics of the subject area with the infiltration capacity of soil and recovery of depression storage and was examined appropriately by sensitivity analysis. This study presented the average annual COSs and number of COSs when the interceptor capacity is in the range 3xDWF(dry weather flow). Also, calculated the average annual mass of pollutant lost in CSOs using Event Mean Concentration. Finally, this study presented a dicision of storage volume for CSOs reduction and water quality protection.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.13 no.3
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• pp.59-67
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• 1993

The variations of the natural frequencies and the peak response acceleration at the top of prestressed concrete reactor building due to random variability and/or model uncertainty of structural parameters are studied. The results may be used as essential input parameters in seismic probabilistic risk assessment or seismic margin assessment of the reactor building. The sensitivity test of each structural parameter is first performed to determine the most influential parameter upon the natural frequency of structure model. Then Monte Carlo simulation technique is applied to evaluate the effect of parameter variation on the natural frequencies and the peak response acceleration. The acceleration time history is obtained by direct integration scheme. As the study results, it is found that the fundamental natural frequency and the peak response acceleration at the top of the building are most strongly affected by Young's modulus among the structural parameters, in which the value of mean plus one standard deviation obtained by probabilistic approach deviates up to about (+)12% from the result of deterministic method. Considering the uncertainty of flexural rigidity, the structural responses vary in range of (-)4%~(+)14%.

• Journal of Korea Water Resources Association
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• v.43 no.4
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• pp.325-336
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• 2010

This study presents the alteration of flow regime by effects of dams and water use in the Geum River Basin. The surface water use rate and the Impounded Runoff (IR) index were examined to assess the pressure indicators of the flow alteration. We applied the flow duration curve, flow regime coefficient, flood and low-flow frequency analysis as well as Range of Variability Approach (RVA) to investigate the quantitative changes in natural flow regimes. The results indicate that the high flow decreased and low flow increased respectively compared to the natural flow regimes at eight gauging stations. The Geum river is regulated by 139 dams and reservoirs storing 24% of the annual mean discharge and has high surface water use rate of 36%. These indicators are main pressure factors to alter flow regimes.

• Tuberculosis and Respiratory Diseases
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• v.78 no.2
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• pp.78-84
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• 2015

Background: Reports of therapeutic drug monitoring (TDM) for second-line medications to treat multidrug-resistant tuberculosis (MDR-TB) remain limited. Methods: A retrospective cohort from the Virginia state tuberculosis (TB) registry, 2009-2014, was analyzed for TDM usage in MDR-TB. Drug concentrations, measured at time of estimated peak ($C_{max}$), were compared to expected ranges. Results: Of 10 patients with MDR-TB, 8 (80%) had TDM for at least one drug (maximum 6 drugs). Second-line drugs tested were cycloserine in seven patients (mean $C_{2hr}$, $16.6{\pm}10.2{\mu}g/mL$; 4 [57%] below expected range); moxifloxacin in five (mean $C_{2hr}$, $3.2{\pm}1.5{\mu}g/mL$; 1 [20%] below); capreomycin in five (mean $C_{2hr}$, $21.5{\pm}14.0{\mu}g/mL$; 3 [60%] below); para-aminosalicylic acid in five (mean $C_{6hr}$, $65.0{\pm}29.1{\mu}g/mL$; all within or above); linezolid in three (mean $C_{2hr}$, $11.4{\pm}4.1{\mu}g/mL$, 1 [33%] below); amikacin in two (mean $C_{2hr}$, $35.3{\pm}3.7{\mu}g/mL$; 1 [50%] below); ethionamide in one ($C_{2hr}$, $1.49{\mu}g/mL$, within expected). Two patients died: a 38-year-old woman with human immunodeficiency virus/acquired immune deficiency syndrome and TB meningitis without TDM, and a 76-year-old man with fluoroquinolone-resistant (pre-extensively drug-resistant) pulmonary TB and low linezolid and capreomycin concentrations. Conclusion: Individual pharmacokinetic variability was common. A more standardized approach to TDM for MDR-TB may limit over-testing and maximize therapeutic gain.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.11
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• pp.2435-2441
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• 2010

A global healthcare system based on M2M technology is proposed to support a good mobility, flexibility and scalability to the patients in 6LoWPAN. Sensor nodes integrated with wearable sensors are linked to gateway with IEEE 802.15.4 protocol and 6LoWPAN protocol for data acquisition and transmission purpose via external network. In the server, heart rate variability signals are obtained by signal processing and used for time and frequency domain performance analysis to evaluate the patient's health status. Our approach for global healthcare system with non-invasive and continuous IP-based communication is managed to process large amount of biomedical signals in the large scale of service range accurately.