• Nuclear Engineering and Technology
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• 제51권3호
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• pp.894-903
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• 2019

An approach for collapse risk assessment is proposed to evaluate the vulnerability of electric cabinet in nuclear power plants. The lognormal approaches, namely maximum likelihood estimation and linear regression, are introduced to establish the fragility curves. These two fragility analyses are applied for the numerical models of cabinets considering various boundary conditions, which are expressed by representing restrained and anchored models at the base. The models have been built and verified using the system identification (SI) technique. The fundamental frequency of the electric cabinet is sensitive because of many attached devices. To bypass this complex problem, the average spectral acceleration $S_{\bar{a}}$ in the range of period that cover the first mode period is chosen as an intensity measure on the fragility function. The nonlinear time history analyses for cabinet are conducted using a suite of 40 ground motions. The obtained curves with different approaches are compared, and the variability of risk assessment is evaluated for restrained and anchored models. The fragility curves obtained for anchored model are found to be closer each other, compared to the fragility curves for restrained model. It is also found that the support boundary conditions played a significant role in acceleration response of cabinet.

• 한국지리정보학회지
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• 제12권2호
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• pp.120-131
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• 2009

본 연구는 다핵구조를 형성하고 있는 대도시의 도시공간구조 진단을 위해 도심 및 부도심의 인구분포상의 구심력 및 유효범위의 변동성을 측정하였다. 이를 위해 부산광역시를 대상으로 1995년부터 2005년까지 5년 간격으로 도심 및 부도심의 인구구심력의 유효범위 변화를 측정하고자 5km 단위로 범위를 확장하여 인구밀도함수 중 음지수함수를 활용한 결정계수 값의 변동성을 분석하였다. 이를 통해 인구분포에 대한 공간적 영향권역의 변동성을 파악하여 도심 및 부도심의 생성, 성장, 쇠퇴 등의 진행과정에 따른 각 과정별 도심 및 부도심의 인구구심력의 유효범위와 도심 및 부도심간의 충돌과정에서의 유효범위 변화과정을 분석하였다. 분석결과를 요약하면 중앙동은 지속적인 결정계수의 감소를 보이고 있으며 서면(부전동)은 설명력이 큰 변화없이 유지되고 있는 것으로 나타났다. 도심으로부터 5km씩 거리를 늘려 인구밀도함수를 적용한 경우에도 부전동의 경우는 10km이후부터 중앙동은 15km구간 이후부터 대체로 증가하였다. 전체적으로는 부산의 인구가 감소추세임에도 불구하고 지속적인 분산화 단계인 것으로 나타나 보다 효율적인 도시공간구조를 형성하기 위해 도심 및 부도심지역의 도심기능강화와 인접지역의 양호한 주거지역 공급이 필요한 것으로 판단된다. 본 연구의 결과는 도시공간구조의 변동성이 갖는 구체적인 공간적 차원의 정보를 제시하여 효율적 공간구조의 재편을 위한 정책적 접근의 기초자료로의 활용이 기대된다.

• 한국대기환경학회지
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• 제34권1호
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• pp.101-119
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• 2018

In this study, we analyzed long-term measurements and air quality simulation results of four criteria air pollutants ($PM_{10}$, $O_3$, $NO_2$, and $SO_2$) for 10 years, from 2006 to 2015, with emphasis on trends of annual variabilities. With the observation data, we conducted spatial interpolation using the Kriging method to estimate spatial distribution of pollutant concentrations. We also performed air quality simulations using the CMAQ model to consider the nonlinearity of the secondary air pollutants such as $O_3$ and the influence of long-range transport. In addition, these simulations are used to deduce the effect of long-term meteorological variations on trends of air quality changes because we fixed the emissions inventory while changing meteorological inputs. The nation-wide inter-annual variability of modeled $PM_{10}$ concentrations was $-0.11{\mu}g/m^3/yr$, while that of observed concentrations was $-0.84{\mu}g/m^3/yr$. For the Seoul Metropolitan Area, the inter-annual variability of observed $PM_{10}$ concentrations was $-1.64{\mu}g/m^3/yr$ that is two times rapid improvement compared to other regions. On the other hand, the inter-annual variability of observed $O_3$ concentrations is 0.62 ppb/yr which is larger than the simulated result of 0.13 ppb/yr. Magnitudes of differences between the modeled and observed inter-annual variabilities indicated that decreasing trend of $PM_{10}$ and increasing trend of $O_3$ are more influenced by emissions and oxidation states than meteorological conditions. We also found similar patterns in $NO_2$. However, $NO_2$ trends showed greater regional and seasonal differences than other pollutants. The analytic approach used in this study can be applicable to estimate changes in factors determining air quality such as emissions, weather, and surrounding conditions over a long term. Then analysis results can be used as important data for air quality management planning and evaluation of the chronic impact of air quality.

• 대한기계학회논문집A
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• 제26권10호
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• pp.2073-2081
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• 2002

In product design and manufacturing, axiomatic design provides a systematic approach for the decision-making process. Two axioms have been defined such as the Independence Axiom and the Information Axiom. The Information Axiom states that the best design among those that satisfy the independence axiom is the one with the least information content. In other words, the best design is the one that has the highest probability of success. On the other hand, the Taguchi robust design is used in the two-step process; one is "reduce variability," and the other is "adjust the mean on the target." The two-step can be interpreted as a problem that has two FRs (functional requirements). Therefore, the Taguchi method should be used based on the satisfaction of the Independence Axiom. Common aspects exist between the Taguchi method and Axiomatic Design in that a robust design is induced. However, different characteristics are found as well. The Taguchi method does not have the design range, and the probability of success may not be enough to express robustness. Our purpose is to find the one that has the highest probability of success and the smallest variation. A new index is proposed to satisfy these conditions. The index is defined by multiplication of the robustness weight function and the probability density function. The robustness weight function has the maximum at the target value and zero at the boundary of the design range. The validity of the index is proved through various examples.gh various examples.

• 한국물환경학회지
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• 제23권4호
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• pp.490-497
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• 2007

A Combined sewer overflows (CSOs) are themselves a significant source of water pollution. Therefore, the control of urban drainage for CSOs reduction and receiving water quality protection is needed. Examples in combined sewer systems include downstream storage facilities that detain runoff during periods of high flow and allow the detained water to be conveyed by an interceptor sewer to a centralized treatment plant during periods of low flow. The design of such facilities as stormwater detention storage is highly dependant on the temporal variability of storage capacity available (which is influenced by the duration of interevent dry periods) as well as the infiltration capacity of soil and recovery of depression storage. As a result, a continuous approach is required to adequately size such facilities. This study for the continuous long-term analysis of urban drainage system used analytical probabilistic model based on derived probability distribution theory. As an alternative to the modeling of urban drainage system for planning or screening level analysis of runoff control alternatives, this model have evolved that offer much ease and flexibility in terms of computation while considering long-term meteorology. This study presented rainfall and runoff characteristics of the subject area using analytical probabilistic model. This study presented the average annual COSs and number of COSs when the interceptor capacity is in the range $3{\times}DWF$ (dry weather flow). Also, calculated the average annual mass of pollutant lost in CSOs using Event Mean Concentration. Finally, this study presented a decision of storage volume for CSOs reduction and water quality protection.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2005년도 학술발표회 논문집
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• pp.1199-1203
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• 2005

Combined sewer overflows(CSOs) are themselves a significant source of water pollution. Therefore, the control of urban drainage for CSOs reduction and receiving water quality protection is needed. Examples in combined sewer systems include downstream storage facilities that detain runoff during periods of high flow and allow the detained water to be conveyed by an interceptor sewer to a centralized treatment plant during periods of low flow. The design of such facilities as stormwater detention storage is highly dependant on the temporal variability of storage capacity available(which is influenced by the duration of interevent dry periods) as well as the infiltration capacity of soil and recovery of depression storage. As a result, a contiunous approach is required to adequately size such facilities. This study for the continuous long-term analysis of urban dranage system used analytical Probabilistic model based on derived probability distribution theory. As an alternative to the modeling of urban drainage system for planning or screening level analysis of runoff control alternatives, this model have evolved that offer much ease and flexibility in terms of computation while considering long-term meteorology. This study presented rainfall and runoff characteristics or the subject area using analytical Probabilistic model. Runoff characteristics manifasted the unique characteristics of the subject area with the infiltration capacity of soil and recovery of depression storage and was examined appropriately by sensitivity analysis. This study presented the average annual COSs and number of COSs when the interceptor capacity is in the range 3xDWF(dry weather flow). Also, calculated the average annual mass of pollutant lost in CSOs using Event Mean Concentration. Finally, this study presented a dicision of storage volume for CSOs reduction and water quality protection.

• 대한토목학회논문집
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• 제13권3호
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• pp.59-67
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• 1993

부분구조법(部分構造法)으로 프리스트레스드 콘크리트 원자로격납건물(原子爐格納建物)의 지진에 대한 확률위험도분석이나 내진 안전여유평가시 상부구조에 관한 입력자료(入力資料)가 되는 구조물(構造物)의 고유전동수와 구조물 상부에서의 최대가 속도값의 구조변수(構造變數)에 대한 변동성이 연구되었다. 본 연구는 먼저 구조모델의 고유진동수에 가장 큰 영향을 미치는 구조변수를 결정하기 위하여 각 구조변수(構造變數)의 상대적(相對的) 민감도(敏感度)를 분석(分析)하였고, 각 변수의 결정에 포함될 수 있는 불확실성(不確實性)의 정도를 고려하여 Monte Carlo 수치모형실험을 수행하였다. 최대 가속도값의 변화는 직접적분(直接積分)에 의한 시간이력곡선법으로 분석되었다. 연구결과로 첫번째모드의 고유 진동수와 건물 정상부의 최대가속도값은 각 변수중 탄생계수의 영향을 가장 크게 받으며, 결정론적 방법으로 구한 값과 비교할 때 확률론적 방법으로 구한 값(평균+표준편차)은 (+)12% 정도 변함을 알 수 있다. 또한 휨강성의 불확실성을 고려하면 동적응답은 (-)4%~(+)14% 정도 달라진다.

• 한국수자원학회논문집
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• 제43권4호
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• pp.325-336
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• 2010

본 연구에서는 금강유역의 물이용과 댐의 영향에 의한 하천유황의 변화를 평가하였다. 유황변화의 압력지표로서 하천수 이용률과 담수지수를 분석하였다. 유황의 정량적인 변화 분석을 위하여 유황곡선, 유황계수, 홍수 및 갈수 빈도분석과 유량변동분석법을 적용하였다. 8개 분석 대상지점의 결과는 댐 건설전의 유황과 비교할 때 댐과 물이용의 영향으로 고유량 범위에서는 감소하고, 저유량 범위에서는 증가하고 있음을 구체적인 수치로 확인하였다. 금강유역은 연평균유출량의 24%를 저류할 수 있는 139개의 댐과 저수지에 의해 유황이 조절되고 지표수의 이용률이 36%로서 이들의 지표가 유황변화의 압력요인이 되고 있다.

• Tuberculosis and Respiratory Diseases
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• 제78권2호
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• pp.78-84
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• 2015

Background: Reports of therapeutic drug monitoring (TDM) for second-line medications to treat multidrug-resistant tuberculosis (MDR-TB) remain limited. Methods: A retrospective cohort from the Virginia state tuberculosis (TB) registry, 2009-2014, was analyzed for TDM usage in MDR-TB. Drug concentrations, measured at time of estimated peak ($C_{max}$), were compared to expected ranges. Results: Of 10 patients with MDR-TB, 8 (80%) had TDM for at least one drug (maximum 6 drugs). Second-line drugs tested were cycloserine in seven patients (mean $C_{2hr}$, $16.6{\pm}10.2{\mu}g/mL$; 4 [57%] below expected range); moxifloxacin in five (mean $C_{2hr}$, $3.2{\pm}1.5{\mu}g/mL$; 1 [20%] below); capreomycin in five (mean $C_{2hr}$, $21.5{\pm}14.0{\mu}g/mL$; 3 [60%] below); para-aminosalicylic acid in five (mean $C_{6hr}$, $65.0{\pm}29.1{\mu}g/mL$; all within or above); linezolid in three (mean $C_{2hr}$, $11.4{\pm}4.1{\mu}g/mL$, 1 [33%] below); amikacin in two (mean $C_{2hr}$, $35.3{\pm}3.7{\mu}g/mL$; 1 [50%] below); ethionamide in one ($C_{2hr}$, $1.49{\mu}g/mL$, within expected). Two patients died: a 38-year-old woman with human immunodeficiency virus/acquired immune deficiency syndrome and TB meningitis without TDM, and a 76-year-old man with fluoroquinolone-resistant (pre-extensively drug-resistant) pulmonary TB and low linezolid and capreomycin concentrations. Conclusion: Individual pharmacokinetic variability was common. A more standardized approach to TDM for MDR-TB may limit over-testing and maximize therapeutic gain.

• 한국정보통신학회논문지
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• 제14권11호
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• pp.2435-2441
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• 2010

본 논문에서는 M2M 기반의 글로벌 헬스케어 모니터링 시스템을 구축하여 헬스케어 분야에 있어 기존의 센서네트워크의 확장성과 이동성을 보완하여 더욱더 안정적이고 신뢰성 있는 건강상태 정보를 제공하고자 하였다. 센서 노드는 웨어러블 심전도 및 맥파 센서와 결합되어 있으며, 각각의 생체신호를 수집하여 IEEE 802.15.4 표준 프로토콜과 6LoWPAN 프로토콜을 통해 외부 인터넷 망을 거쳐 서버로 전송한다. 또한 서버 프로그램은 측정된 생체신호를 통해 HRV 신호를 검출하였으며, HRV 신호를 이용한 시간 영역 및 주파수 영역 분석을 통해 환자의 스트레스 상태를 판단하도록 하였다. 이로써 제안된 시스템은 기존의 네트워크 인프라를 최대한 활용할 수 있는 장점을 가지고 있으며, 각각의 센서노드에 IP를 부여하여 헬스케어 서비스의 적용범위가 좁은 지역을 벗어나 범국가적으로 확대될 수 있도록 하였다.