• 제목/요약/키워드: Randomized Clinical Trials

검색결과 959건 처리시간 0.029초

China National Knowledge Infrastructure 검색을 통한 내측경골 피로증후군 치료의 중의 임상 연구 동향 분석 (Review of Studies for Traditional Chinese Medicine on Treatment of Medial Tibial Stress Syndrome through China National Knowledge Infrastructure Search)

  • 박정현;정수현
    • 한방재활의학과학회지
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    • 제33권4호
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    • pp.157-165
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    • 2023
  • Objectives The purpose of this study was to analyze trends in traditional Chinese treatment of medial tibial stress syndrome (MTSS) and suggest directions for future research in Korea. Methods We investigated clinical studies using traditional Chinese medicine for treatment of MTSS through China National Knowledge Infrastructure search. Fourteen studies published from 2000 to 2022 were adopted and analyzed. We examined authors, type of study design, publishied year, intervention, treatment effectiveness. Results Among 14 studies, 8 were case reports and 6 were randomized controlled trials. Four interventions were used in 14 studies. Acupuncture and physical therapy were most frequently used interventions, each used in 12 studies. For evaluation of treatment effectness, 7 outcome measurements were used, effective rate was the most commonly used measurement. All of 14 studies showed good treatment results. Conclusions Through this study, we were able to identify current trends of Chinese medicine treatment for MTSS. Based on this, more study should be conducted to accumulate evidence for Korean medicine treatment of MTSS.

파킨슨병의 두침치료에 대한 최신 연구동향 분석: China National Knowledge Infrastructure, PubMed 검색을 중심으로 (Current Research Trend Analysis of Scalp Acupuncture Teatment for Parkinson's Disease Using the Search Results of China National Knowledge Infrastructure and PubMed)

  • 이동준;신병철
    • 한방재활의학과학회지
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    • 제33권4호
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    • pp.95-107
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    • 2023
  • Objectives The purpose of this study is to help find the future prospects by analyzing the trends of scalp acupuncture treatment for Parkinson's disease (PD) by searching the China National Knowledge Infrastructure (CNKI) and PubMed. Methods We searched clinical studies adopting scalp acupuncture treatment as a main intervention for PD through the searching the database of CNKI and PubMed. We analyzed the characteristics of selected studies especially according to study design, publication year, sample size, treatment period, treatment methods, outcomes criteria and adverse events. Results Twelve randomized controlled trials studies published from January 1, 2012 to July 1, 2023 were selected. In these studies, two types of scalp acupuncture treatments were performed and the most common treatment was Jiao shunfa's scalp acupuncture with fine needles. The most commonly used acupoints were "Chorea tremor control area", 風池 (GB20), 四神聰 (EX-HN1) and 百會 (GV20). The most commonly used outcome measures were effective rate, unified Parkinson disease rating scale (UPDRS) and UPDRS-III. Conclusions Through these results, we found that the Chinese review literature positively reported the effects of scalp acupuncture on PD. However, more high-quality evaluation using the well-designed studies including more objective outcomes should be required.

급성 허혈성 뇌졸중의 혈관 내 치료 (Endovascular Treatment of Acute Ischemic Stroke)

  • 김준휘;김병문
    • 대한영상의학회지
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    • 제81권3호
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    • pp.562-576
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    • 2020
  • 급성 허혈성 뇌졸중은 심각한 후유증이나 사망에 이르는 가장 큰 원인 질환들 중 하나이다. 제2세대 혈전제거기구가 도입된 이후로 급성 허혈성 뇌졸중에서 혈관 내 재개통 치료는 급속히 발전해 왔고, 최근에는 표준 치료 중의 하나가 되었다. 이 종설에서는 급성 허혈성 뇌졸중에서 혈관 내 치료와 고식적인 치료를 무작위 배정으로 비교한 임상 연구들의 결과를 간략히 기술하고, 새로이 개정된 급성 허혈성 뇌졸중에서의 혈관 내 치료의 적응증과, 현재 혈관내 치료에 쓰이는 기구들과 방법에 대해 알아보고자 한다.

E-learning system to improve the endoscopic diagnosis of early gastric cancer

  • Kenshi Yao;Takashi Yao;Noriya Uedo;Hisashi Doyama;Hideki Ishikawa;Satoshi Nimura;Yuichi Takahashi
    • Clinical Endoscopy
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    • 제57권3호
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    • pp.283-292
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    • 2024
  • We developed three e-learning systems for endoscopists to acquire the necessary skills to improve the diagnosis of early gastric cancer (EGC) and demonstrated their usefulness using randomized controlled trials. The subjects of the three e-learning systems were "detection", "characterization", and "preoperative assessment". The contents of each e-learning system included "technique", "knowledge", and "obtaining experience". All e-learning systems proved useful for endoscopists to learn how to diagnose EGC. Lecture videos describing "the technique" and "the knowledge" can be beneficial. In addition, repeating 100 self-study cases allows learners to gain "experience" and improve their diagnostic skills further. Web-based e-learning systems have more advantages than other teaching methods because the number of participants is unlimited. Histopathological diagnosis is the gold standard for the diagnosis of gastric cancer. Therefore, we developed a comprehensive diagnostic algorithm to standardize the histopathological diagnosis of gastric cancer. Once we have successfully shown that this algorithm is helpful for the accurate histopathological diagnosis of cancer, we will complete a series of e-learning systems designed to assess EGC accurately.

비급성 요통에 대한 무작위대조군 임상연구 수행을 위한 추나표준화 설문조사 보고 (The Survey on the Standardization of Chuna Manual Technique for Operating RCT of Non-acute Low Back Pain)

  • 김병준;황의형;허광호;황만석;허인;송윤경;이정한;고연석;박태용;조재흥;이은정;문수정;하인혁;이민호;신병철
    • 척추신경추나의학회지
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    • 제10권2호
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    • pp.13-25
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    • 2015
  • Objectives : To find out the standardized chuna manual technique for non-acute low back pain. Methods : The survey questions were developed by the consensus from the professor who major in Rehabillitation Medicine of Korean Medicine(RMKM). August 15th to september 1st 2015, the questionnaire was given to 23 RMKM doctors by e-mail. 20(90.9%) the questionnaire were retrieved out. Standardized technique of chuna were selected through experts consesus based on questionaire results. Results : Two essential techniques and two selective techniques were selected as standardized Chuna manual technique for lumbar region. Six essential technique and one selective technique were selected as standardized Chuna manual technique for iliac region. Conclusions : This is the first consensus of experts opinion for Chuna manual technique for operating randomized controlled trials(RCT). These reports are helpful for Korean Medicine doctor who operate Chuna manual technique and expected to make clinical evidence of Chuna manual medicine

최근 5년간 교통사고 후유증의 한의학적 치료에 대한 국내 연구 동향 (The Domestic Trends of Korean Medicine Treatments on Traffic Accident for Recent 5 Years)

  • 최영일;김민영;최희승;정윤규;노해린;김세준;신동재
    • 척추신경추나의학회지
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    • 제8권1호
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    • pp.27-38
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    • 2013
  • Objectives : The purpose of this study is to investigate the latest trends of korean Medicine treatments on traffic accident for recent 5 years. Methods : We investigated the studies on korean Medicine treatments for traffic accident via searching 6 Korean web databases. As a result, 65 research papers were found to be analyzed according to their published year, the titles of journals, the types of study, the number of cases, the sites of injury, the types of treatments the instruments for assessment and ethics approvals. Results : 65 articles were published since 2008. The studies on korean Medicine treatments about traffic accident were mainly published in Journal of Oriental Rehabilitation Medicine. 10 case studies, 14 case series, 11 non randomized controlled trials, 21 randomized controlled trials and 9 systemic reviews had been under research. The most frequently occurred symptoms were neck pain and low back pain. In most studies, various korean Medicine treatments were used to treat the symptoms. Visual analogue scale(VAS) and neck disability index(NDI) were used as primary assessments. In most clinical studies, there were no mention about approval of institutional review board(IRB). Conclusion : In this study, we analyzed the trends of korean Medicine treatments on traffic accident from 2008 to 2012. Reviewing the domestic trends of studies on korean Medicine treatments for traffic accident and examining the strong and weak points of those treatments are essential for the future studies. It is needed to adopt the qualitative methods of evaluation in order to develop a level of evidence.

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간암에 대한 한약치료: 체계적 문헌고찰 및 메타분석의 프로토콜 (Herbal Medicine for Liver Cancer: A Protocol for Systematic Review and Meta-Analysis)

  • 권승원;송가연;양승보
    • 대한한방내과학회지
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    • 제43권4호
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    • pp.559-566
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    • 2022
  • 서론: 본 체계적 문헌 고찰의 프로토콜 논문은 간암의 한약 치료에 대한 효과와 안전성의 근거를 제시하는 것을 목표로 한다. 방법: 본 체계적 문헌 고찰은 간암에 한약 치료에 대한 무작위 대조 임상시험을 포함할 것이다. 오직 무작위 대조 임상시험 유형의 임상 연구만 포함할 것이다. 시험군의 한약 치료는 한약을 사용한 모든 제형을 포함할 것이며, 대조군은 다른 치료, 플라시보 치료, 서양의학적 치료 등을 포함할 것이다. 다음 11개의 데이터베이스를 활용하여 검색할 것이다: the Cochrane Database of Systematic Reviews, MEDLINE, EMBASE, AMED, CINAHL, Chinese database(CNKI), 그리고 다섯 개의 한국데이터베이스(OASIS, DBpia, RISS, KISS, and NDSL). 연구의 선정, 데이터 추출 및 분석 등의 업무는 3명의 연구자가 독립적으로 수행할 것이다. 비뚤림 위험 평가를 포함한 연구의 질적 평가는 Cochrane risk-of-bias assessment tool을 사용할 것이다. 결과: 본 간암에 대한 한약 치료의 체계적 문헌 고찰은 최신의 근거를 요약적이고 분석적으로 제공할 것이다. 결론: 간암의 한약 치료에 대한 효과와 안전성의 근거를 제시할 것이며, 이는 종양학이나 한의학과 보완·대체의료 분야의 종사자들에게 유용한 정보를 제공할 것이다.

류마티스 관절염 치료제와 병용한 독활기생탕의 효과 및 안전성: 체계적 문헌고찰 및 메타분석 프로토콜 (The Effectiveness and Safety of Dokwhalkisaeng-tang Combined with the Medication on Rheumatoid Arthritis: A Study Protocol for Systematic Review and Meta-analysis)

  • 채수연;정찬영;김주희;김은정;서병관;황민섭;박성식;김경호;윤종화;성원석
    • 대한한의학방제학회지
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    • 제30권2호
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    • pp.95-100
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    • 2022
  • Objectives : Recent studies reported that Dokwhalkisaeng-tang (DHJST) could relieve the clinical rheumatoid arthritis (RA) symptoms and the level of RA-related blood test. However, evidence-based review on effectiveness and safety of DHJST with medication on RA was not yet provided. Methods : Searching randomized controlled trials on the use of DHJST for RA will be performed using multiple electronic databases, manual search, and contact to author. Studies will be selected according to the pre-defined criteria and collected data on study participants, interventions, control groups, outcome measurements, the results, adverse events, and risk of bias will be summarized. Primary outcome will be the disease activity score (including effective rate, swollen joint count, tender joint count, and morning stiffness), and the secondary outcomes will be RA-related blood test and adverse events. We will use Review Manager software to perform a meta-analysis, Cochrane Collaboration "risk of bias" tool for assessing the risk of bias, and Grades of Recommendation, Assessment, Development and Evaluation for the determination of quality of evidence. Results : We are going to investigate the effectiveness and safety of DHJST with medication for RA. Conclusion : This study will provide reliable evidence on whether DHJST combined with medicine is more effective on RA than medicine monotherapy.

경피적 관상동맥중재술 후 재협착 예방에 대한 한약의 효과 : 무작위배정 대조군 임상연구에 대한 체계적 문헌고찰 및 메타분석 (Effect of Herbal Medicines on Preventing Restenosis After Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis of Randomized Controlled Trials)

  • 허나연;안수빈;김홍준;장인수
    • 대한한방내과학회지
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    • 제44권3호
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    • pp.387-401
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    • 2023
  • Objective: This study was conducted to investigate the preventive effect of herbal medicines on restenosis after percutaneous coronary intervention (PCI) by reviewing randomized controlled trials (RCTs). Methods: RCTs were searched for herbal medicine treatment after PCI using eight online databases (PubMed, CNKI, Wanfang, J-STAGE, OASIS, ScienceON, KTKP, and KISS). Studies that confirmed restenosis through coronary angiography at follow-up were selected according to the inclusion and exclusion criteria. The primary outcome was the restenosis rate, and the secondary outcome was the angina recurrence rate. Data were extracted from the final selected studies according to the research methodology and then analyzed with Review Manager 5.4.1. Study quality was assessed using Cochrane's risk-of-bias (RoB) tool. Results: Of the 252 papers obtained through the primary search, nine studies that met the selection criteria were finally selected. In these nine studies, herbal medicine combined with western medicine was used for the experimental group, and western medicine treatment was used alone for the control group. The meta-analysis result revealed that the restenosis rate and angina recurrence rate were significantly lower in the experimental group than in the control group (RR=0.34, 95% CI: 0.22-0.53, p<0.00001, I2=0% and RR=0.47, 95% CI: 0.29-0.78, p=0.004, I2=0%, respectively). Furthermore, the quality of studies assessed by Cochrane's RoB was low. Conclusions: This study showed that the combined treatment of herbal medicine and western medicine was effective in preventing restenosis and angina after PCI. As the number of papers included in this study was small, a large number of high-quality clinical studies should be considered in the future.

사경증의 한방 치료에 대한 체계적 문헌고찰 (2018년부터 2023년 연구를 중심으로) (A Systematic Review of the Korean Medicine Treatments for Torticollis (Focused on Research from 2018 to 2023))

  • 서경준;최종찬;지민준;권도영;양재은;구지향;이은정;오민석
    • 한방재활의학과학회지
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    • 제34권2호
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    • pp.29-49
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    • 2024
  • Objectives The purpose of this study is to systemically review the recent studies in the Korean medicine treatments for torticollis. Methods We search the clinical studies from January 1, 2018 to December 31, 2023. The studies were searched through 10 databases (Oriental Medicine Advanced Searching Integrated System, Korean studies Information Service System, Research Information Sharing Service, Korean Medical Database, ScienceON, PubMed, Cochrane Library, Embase, Wanfang Data, China National Knowledge Infrastructure). Results A total of 19 studies were included in the study. 12 studies were case report studies, 5 studies were randomized controlled trials, 2 studies were non-randomized controlled trials. Of the 19 interventions, Chuna was the most used in this study and of the 28 evaluation tools, Sternocleidomastoid thickness was the most used in this study except efficiency rate. All 19 studies had improvements after treatment, and 8 studies had statistically significant improvements. As a result of the study, we found that Chuna, GB, GB20, BL10, Glycyrrhiza uralensis were commonly used Korean medicine treatments for torticollis. Conclusions We analyzed the Korean medicine treatments for torticollis. Through this study, we found that the Korean medicine was effective for torticollis. However, more research is needed to confirm the more detailed effect.