• Title/Summary/Keyword: Randomized Clinical Trials

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Investigation of Clinical Research of Acupuncture Treatment on Urinary Incontinence in Medline (MEDLINE과 SCOPUS 검색을 통한 요실금에 대한 침구치료의 국외 연구 동향 분석)

  • Kim, Eun-Gyung;Hwang, Deok-Sang;Lee, Jin-Moo;Lee, Chang-Hoon;Jang, Jun-Bok;Lee, Kyung-Sub
    • The Journal of Korean Obstetrics and Gynecology
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    • v.26 no.2
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    • pp.166-177
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    • 2013
  • Purpose: The purpose of this study is to examine acupuncture and moxibustion treatment suggested on the papers of urinary incontinence(UI) in medicine journals and to establish the future direction. Methods: The papers which were associated with acupuncture and HG published between 1992 and 2012 in Medline and Scopus were searched. Results: 14 studies met the condition. They were 3 randomized controlled trials(RCTs) and 5 clinical studies. 8 studies revealed that acupuncture and moxibustion have efficacies in UI. Conclusions: From the paper research, acupuncture and moxibustion treatment seem to be effective on UI. However, due to the lack sufficient research of UI, it would be necessary to fulfill further study about the period of acupuncture and moxibustion treatment on UI and the selection of acupoint through well-designed study and establish standard of evidence of them.

The Analysis of Type D Personality Research as a Psychosocial Risk Factor in Cardiovascular Disease for Elders with a Chronic Disease (심혈관질환의 심리사회적 위험요인으로써의 D유형 성격에 관한 논문 분석)

  • Song, Eun-Kyeung;Son, Youn-Jung
    • Journal of Korean Academy of Nursing
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    • v.38 no.1
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    • pp.19-28
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    • 2008
  • Purpose: The purpose of this paper was to examine the relationship between type D personality and cardiovascular disease, and to suggest future research directions. Method: A literature search was conducted from the following nine databases: 1) MEDLINE, 2) CINAHL, 3) Pubmed Unrestricted, 4) PsycINFO, 5) KISS, 6) RICHIS, 7) RISS4U, and 8) Nanet. The combinations of the words, "type D personality", "personality", "heart", "cardiovascular", and "coronary" were used for keyword searches to find relevant articles. Twenty eight studies were identified. Result: Type D personality has been associated with increased morbidity and mortality in patients with established cardiovascular disease. Type D patients are also at increased risk for impaired quality of life, and seem to benefit less from medical and invasive treatment. Conclusion: There is substantial evidence for a relationship between type D personality and clinical outcomes related to cardiovascular disease. Randomized clinical trials are needed to further evaluate the value of controlling type D personality to improve survival and reduce morbidity in patients with cardiovascular disease. Accumulating evidence from this analysis indicates the urgent need to adopt a personality approach in order to optimize the identification of patients at risk for stress related cardiac events.

A Review of Research on Acupuncture and Moxibustion Treatment for De Quervain's Stenosing Tenosynovitis

  • Kong, Hae Jin;Kang, Jae Hui;Yun, Gee Won;Oh, Seo Young;Lee, Hyun
    • Journal of Acupuncture Research
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    • v.34 no.3
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    • pp.71-90
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    • 2017
  • Objectives : This study was performed to review articles concerning acupuncture and moxibustion treatment for De Quervain's Stenosing Tenosynovitis. Methods : On-line databases including Cochrane Library, Pubmed, CNKI, NDSL and OASIS were searched to identify articles concerning acupuncture and moxibustion treatment for De Quervain's Stenosing Tenosynovitis (DQST). Several duplicated articles and those not relevant to this topic were excluded, as were review articles and commentaries. Results : Fifty-one studies were identified, which included 28 clinical case studies with 1,227 patients and 23 randomized controlled trials with 2,040 patients. In these studies, acupuncture, acupotomy, moxibustion, pharmacopuncture, and laser acupuncture were used as DQST interventions. Although DQST is a common disease seen in clinical practice, only four of the 51 studies we identified in our search were published in Korean academic journals, all of which used pharmacopuncture. Conclusion : Although the results of the studies to date provide evidence that acupuncture and moxibustion are effective treatments for De Quervain's Stenosing Tenosynovitis, the absence of a standard, objective evaluation tool, and a lack of reporting on the negative side-effects associated with treatment remain important factors that should be addressed in future studies.

A randomized, double-dummy, multicenter non-inferiority clinical trials to evaluate the efficacy and the safety of SKI 306X compared to diclofenac in patients with osteoarthritis of the knee (양측 눈가림, 무작위배정, 다기관공동 제 3상 임상시험 결과 - 퇴행성 관절염에 대한 SKI 306X정과 Diclofenac과의 비열등성 임상시험)

  • Jung Y.B.;Seong S.C.;Lee M.C.;Shin Y.U.;Kim D.H.;Kim J.M.;Jung Y.K.;Ahn J.H.;Seo J.G.;Park Y.S.;Lee C.S.;Roh K.J.;Han C.K.
    • 대한임상약리학회:학술대회논문집
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    • 2001.12a
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    • pp.24-25
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    • 2001
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A Review on Clinical Research Trends in the Treatment of Hatha-Style Yoga for Post Traumatic Stress Disorder (외상후 스트레스장애에 대한 하타 스타일 요가 치료의 해외 임상연구 동향)

  • Hong, Hee-Yeon;Hong, Min-Ho;Koo, Byung-Su;Kim, Geun-Woo
    • Journal of Oriental Neuropsychiatry
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    • v.31 no.1
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    • pp.13-23
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    • 2020
  • Objectives: The purpose of this study was to review the research trends in the treatment of hatha-style yoga on Post Traumatic Stress Disorder (PTSD). Methods: We searched articles in Pubmed and the China National Knowledge Infrastructure (CNKI) January 2010-December 2019, for studies to treat PTSD using hatha-style yoga. Selected studies were evaluated by the CLEAR-NPT (A Checklist to Evaluate a Report of a Non-pharmacological Trial). Results: Seven randomized controlled clinical trials were selected. PSS-I (PTSD Symptom Scale-Interview) was the most frequently used as diagnostic criteria. The PCL (PTSD Checklist) was also the most commonly used outcome measurement. Of the seven articles, most studies reported that hatha-style yoga was effective to reduce symptoms of PTSD. Conclusions: Hatha-style yoga practice intervention can be used to relieve symptoms of PTSD. More studies should be conducted to make hatha-style yoga as protocol (complementary therapy) for PTSD patients.

Definition and management of odontogenic maxillary sinusitis

  • Kim, Soung Min
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.41
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    • pp.13.1-13.11
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    • 2019
  • Background: Maxillary sinusitis of odontogenic origin, also known as maxillary sinusitis of dental origin or odontogenic maxillary sinusitis (OMS), is a common disease in dental, otorhinolaryngologic, allergic, general, and maxillofacial contexts. Despite being a well-known disease entity, many cases are referred to otorhinolaryngologists by both doctors and dentists. Thus, early detection and initial diagnosis often fail to detect its odontogenic origin. Main body: We searched recent databases including MEDLINE (PubMed), Embase, and the Cochrane Library using keyword combinations of "odontogenic," "odontogenic infection," "dental origin," "tooth origin," "sinusitis," "maxillary sinus," "maxillary sinusitis," "odontogenic maxillary sinusitis," "Caldwell Luc Procedure (CLP)," "rhinosinusitis," "functional endoscopic sinus surgery (FESS)," "modified endoscopy-assisted maxillary sinus surgery (MESS)," and "paranasal sinus." Aside from the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) trial, there have been very few randomized controlled trials examining OMS. We summarized the resulting data based on our diverse clinical experiences. Conclusion: To promote the most efficient and accurate management of OMS, this article summarizes the clinical features of rhinosinusitis compared with OMS and the pathogenesis, microbiology, diagnosis, and results of prompt consolidated management of OMS that prevent anticipated complications. The true origin of odontogenic infections is also reviewed.

Anticoagulation Therapy, Thrombolytic Therapy, and Use of Blood Products in Neonates (신생아에서의 항응고요법, 혈전용해요법 및 혈액제제 사용)

  • Choi, Chang-Won
    • Neonatal Medicine
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    • v.18 no.1
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    • pp.34-41
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    • 2011
  • Neonatal coagulation disorders and thromboembolism require timely management. Failure to treat these conditions at the appropriate time may lead to death or the development of significant long-term sequelae. However, most current guidelines for managing neonatal coagulation disorders and thromboembolism are empiric and not based on randomized clinical trials. Thus, it is not easy to choose an appropriate management strategy for these conditions in clinical settings. In this review, therapeutic guidelines currently utilized in clinics and novel therapeutic options still under investigation are presented and reviewed.

Literature Review of Clinical Usefulness of Heavy Ion Particle as an New Advanced Cancer Therapy (첨단 암 치료로서 중입자치료의 임상적 유용성에 대한 고찰)

  • Choi, Sang Gyu
    • Journal of radiological science and technology
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    • v.42 no.6
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    • pp.413-422
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    • 2019
  • Heavy ion particle, represented carbon ion, radiotherapy is currently most advanced radiation therapy technique. Conventional radiation therapy has made remarkable changes over a relatively short period of time and leading various developments such as intensity modulated radiation therapy, 4D radiation therapy, image guided radiation therapy, and high precisional therapy. However, the biological and physical superiority of particle radiation, represented by Bragg peak, can give the maximum dose to tumor and minimal dose to surrounding normal tissues in the treatment of cancers in various areas surrounded by radiation-sensitive normal tissues. However, despite these advantages, there are some limitations and factors to consider. First, there is not enough evidence, such as large-scale randomized, prospective phase III trials, for the clinical application. Secondly, additional studies are needed to establish a very limited number of treatment facilities, uncertainty about the demand for heavy particle treatment, parallel with convetional radiotherapy or indications. In addition, Bragg peak of the heavy particles can greatly reduce the dose to the normal tissues front and behind the tumor compared to the photon or protons. High precision and accuracy are needed for treatment planning and treatment, especially for lungs or livers with large respiratory movements. Currently, the introduction of the heavy particle therapy device is in progress, and therefore, it is expected that more research will be active.

Systematic Review of Herbal Medicine Fumigation Treatment for Mycotic Vaginitis (Candida Vaginitis) (진균성 질염의 한약 훈증 치료에 대한 체계적 문헌 고찰)

  • Park, Kyung-Dug;Bae, Ju-Eun;Yoon, Young-Jin
    • The Journal of Korean Obstetrics and Gynecology
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    • v.31 no.3
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    • pp.20-32
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    • 2018
  • Objectives: The purpose of this study is to identify the effectiveness of fumigation treatment, provide a clinical basis for fumigation therapy, and develop treatment protocols through consideration of treatment methods and herbal medicines. Methods: We searched for randomized controlled clinical trials using fumigation treatment on mycotic vaginitis in 8 electronic databases such as EMBASE, Pubmed, and CNKI. The results of the studies were analyzed and the risk of bias was assessed by using Cochrane risk of bias tool. A meta-analysis was performed to reveal the effectiveness of fumigation compared to control treatments. Results: We finally selected 5 studies among 54 articles according to inclusion criteria and exclusion criteria. In all selected studies, herbal fumigation was more effective than any control treatment and all the studies were statistically significant. Conclusions: The study provides a basis for applying fumigation treatment to patients with mycotic vaginitis and helps developing a treatment protocol of caring patients of mycotic vaginitis. But the limitation of this study is that the number of studies included is small and quantitative synthesis of all results has not been achieved.

Electoacupuncture for Patients Undergoing Hip Arthroplasty: A Systematic Review and Meta-Analysis (고관절 치환술 환자에 적용한 전침치료: 체계적 문헌고찰 및 메타분석)

  • Oh, Eun-Mi;Hong, Su Min;Kim, Ho-Geol;Lee, Eun-Jung
    • Journal of Korean Medicine Rehabilitation
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    • v.30 no.4
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    • pp.105-117
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    • 2020
  • Objectives The objective of this study is to assess the effectiveness of electroacupuncture for patients with hip arthroplasty. Methods According to participants, intervention, comparison, outcome, study design, we searched for clinical studies that conducted electroacupuncture for patients with hip arthroplasty. Results Finally 11 randomized controlled trials were chosen for systemic review and meta-analysis. The frequently used evaluation tools were Incidence of postoperative cognitive dysfunction (POCD), heart rate, blood pressure. Almost studies showed electroacupuncture has effects for patients with hip arthroplasty. Through meta analysis, Electoacupuncture showed statistically significant effect of reducing the anesthetic dosage and incidence of postoperative psychonosema and adverse reactions in intra-operation period, reducing the incidence of POCD in peri-operation period, incidence of deep venous thrombosis in post-operation period. Conclusion 11 studies reported that electroacupuncture has significant effects on hip arthroplasty. But, many studies were assessed in a probable high risk of bias. And all studies published in one overseas country. So, it requires attention to comprehend this study. To make up for this limitaion, more well designed clinical research are needed.