• 천문학논총
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• 제32권1호
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• pp.305-307
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• 2017

We have identified 22 quasars in the AKARI far-infrared all-sky Bright Source Catalogue, using a matching radius of < 10", and excluding matches which are close to foreground extended sources or cirrus. We have confirmed a relation between quasar optical luminosity and far-infrared luminosity which was found in an earlier study. In addition, we have found that the 11 sources which are at redshift z > 1 are magnified with respect to the predicted far-infrared luminosity, and consider this may be due to gravitational lensing. If confirmed, this would provide a new way to identify lenses; if not, we may have identified an interesting new population of extreme starbursting quasars.

• Bulletin of the Korean Chemical Society
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• 제25권12호
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• pp.1863-1868
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• 2004

Kringle 5 (K5), located outside of angiostain (K1-4) in human plasminogen, displays more potent antiangiogenic activity on endothelial cell proliferation than angiostatin itself. Using a yeast two-hybrid system in vivo, we have recently identified Rgl2 (guanine nucleotide dissociation stimulator (RalGDS)-like factor 2) as a binding protein of human K5. In order to confirm in vitro protein interaction between K5 and Rgl2, we developed bacterial recombinant expression systems for them. K5 and Rgl2 proteins were expressed in high yields and purified into pure forms with His tags and GST fusion, respectively. GST-pull down experiments clearly demonstrated that K5 interacts specifically with Rgl2 in vitro. These results indicate that Rgl2 functions as a receptor protein for K5 in vitro as well as in vivo, leading to anti-angiogenesis through regulating Ras signaling pathways.

• Molecules and Cells
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• 제44권8호
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• pp.613-622
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• 2021

In vertebrate eyes, the retinal pigment epithelium (RPE) provides structural and functional homeostasis to the retina. The RPE takes up retinol (ROL) to be dehydrogenated and isomerized to 11-cis-retinaldehyde (11-cis-RAL), which is a functional photopigment in mammalian photoreceptors. As excessive ROL is toxic, the RPE must also establish mechanisms to protect against ROL toxicity. Here, we found that the levels of retinol dehydrogenases (RDHs) are commonly decreased in phosphatase tensin homolog (Pten)-deficient mouse RPE, which degenerates due to elevated ROL and that can be rescued by feeding a ROL-free diet. We also identified that RDH gene expression is regulated by forkhead box O (FOXO) transcription factors, which are inactivated by hyperactive Akt in the Pten-deficient mouse RPE. Together, our findings suggest that a homeostatic pathway comprising PTEN, FOXO, and RDH can protect the RPE from ROL toxicity.

• BMB Reports
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• 제54권5호
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• pp.272-277
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• 2021

RalBP1 associated EPS domain containing 1 (REPS1) is conserved from Drosophila to humans and implicated in the endocytic system. However, an exact role of REPS1 remains largely unknown. Here, we demonstrated that mitogen activated protein kinase kinase (MEK)-p90 ribosomal S6 Kinase (RSK) signaling pathway directly phosphorylated REPS1 at Ser709 upon stimulation by epidermal growth factor (EGF) and amino acid. While REPS2 is known to be involved in the endocytosis of EGF receptor (EGFR), REPS1 knockout (KO) cells did not show any defect in the endocytosis of EGFR. However, in the REPS1 KO cells and the KO cells reconstituted with a non-phosphorylatable REPS1 (REPS1 S709A), the recycling of transferrin receptor (TfR) was attenuated compared to the cells reconstituted with wild type REPS1. Collectively, we suggested that the phosphorylation of REPS1 at S709 by RSK may have a role of the trafficking of TfR.

• 천문학논총
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• 제27권4호
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• pp.357-360
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• 2012

This paper presents $H{\alpha}$ emission line detections for four galaxies at z > 3.5 made with AKARI as part of the FUHYU mission program. These are the highest-redshift $H{\alpha}$ detections to date in star-forming galaxies. AKARI's unique near-infrared spectroscopic capability has made these detections possible. For two of these galaxies, this represents the first evidence of their redshifts and confirms their physical association with a companion radio galaxy. The star formation rates (SFRs) estimated from the $H{\alpha}$ lines under-predict the SFRs estimated from their far-infrared luminosities by a factor of ~ 2 - 3. We have also detected broad $H{\alpha}$ components in the two radio galaxies which indicate the presence of quasars.

• 복식
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• 제21권
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• pp.207-218
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• 1993

The desire of our contempories who wish to recover humanities fading away and get back recover humanities fading away and get back to the nature is emerging as a main theme of the fashion today the decade of facing 21st century. The prevalence of naturalness-ecology ru-ral peasant look-and ethnic look shows the tendency mentioned above. Kenzo Takada' works which exhibit this naturalness and ethnic look were picked and investigated. The objective of this research is to study the beauty of form and internal and investi-gate in what form the naturaless and Ethnic look in Kenzo's work. The result were as followings : <1> Draped form are mainly used as form and they are made neglecting the body line by straight-cut and provide the wearer ease and freedom of movements <2> As for the color fantastic original colors (red, blue, etc) and natural colors are used. And Strong color contrast is seen. In ethnic look original colors(red, blue, etc.) natural colors and ethnic colors are used. <3> As for the fabric Cotton neat skilk and wool etc are used mainly and use of such natural fibers represents the return to the natural well. <4> As for ornament natural things-straw hat flower feather pebble, shell-are used and exhibit natural feelings strongly. For the ethnic look ornaments representing each country's ethnic atmos-phere by hat scarf and neckcloth made of natural fibers. <5> As for naturalness Flower deer butter-fly leopard and plant etc, are used as motif. As for ethnic look flower geometric motif are used.

• 한국항해학회지
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• 제17권4호
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• pp.43-51
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• 1993

The purposes of this study are to make an analysis the sensible degree in Korea by using the formulas prepared by Watanabe, and to divide the climatic classification by the sensible degree in order to apply in practical life. Most data(air temperature, relative humidity, wind velocity, atmospheric pressure) are extracted from the "Climatic Table of Korea, Volume II(1961~1990)" issued by the Korea Meteorological Administration. As a result of this study, distribution patterns of the sensible degree are similar to isotherms when the wind velocity is zero, and then the sensible degrees are reduced with the increase of latitude. And western coastal and inland regions have larger values than eastern coastal regions in summer. However, the cont-rary distributions are shown in winter. When the wind velocity is not zero, distribution patterns of the sensible degree are influenced by the wind velocity. In summer, the values of central and southern inland regions are especially higher than the coastal regions, and most northern districts and some inland regions (Kangnung, Ulchin, Yongju etc.) have low values in winter. Then, the climate of Korea is divided into four patterns as follows : Yow means the sensible degree when the wind velocity is zero in winter. Yow > 3 : Jeju Island and southern coastal regions Yow = 0~3 : Most southern district and eastern coastal regions of central districts Yow = -3~0 : Most central districts and some eastern coastal regions (Hamheung, Youngheung, Won-san etc.) of northern districts Yow < -3 : Most northern districts and some inland regions(Inje, Hongcheon, Yang-pyeong etc.) of cent-ral districts.districts.

• 대한방사선치료학회지
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• 제6권1호
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• pp.56-60
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• 1994

In the past, brachytherapy was carried out mostly with radium or radon sources. Currently. use of artificially produced radionuclially produced radionuclides such as $^{137}Cs,\;^{192}Ir,\;^{198}Au,\;and\;^{125}I$ is rapidly increasing. Although electrons are often used as an alternative to interstitial implants, brachytherapy continues to remain an important mode of therapy, either alone or combined with external beam. The National Council on Radiation Protection and Measurements(NCRP) recommends that the strength of any ${\gamma}$ emitter should be specified directly in terms of exposure rate in air at a specified distance such as 1m. The air kerma strength is defined as the product of air kerma rate in 'free space' and the square of the disrance of the calibration point from the source center along the perpendicular bisector, i. e., $S_k=K_L{\times}L^2$. Where $S_K$ is the the air kerma strength and K is the air kerma rate at a specified distance L. (usually 1m). Recommended units for all kerma strength are ${\mu}Gym^{2}h^{-1}$.

• 한국작물학회지
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• 제48권5호
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• pp.388-391
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• 2003

Tobacco mosaic virus (TMV), TMV-common strain, causes severe damage at growth, yield and leaf quality on flue-cured tobacco in Korea. Controlling TMV outbreak with cultivating practices and chemicals are limited, thus, the best way would be developing TMV resistant variety. A new flue-cured hybrid, KF118, was developed from a cross of maternal parent MSTC175 and TC853 at the Agro-tech. Research Group, KT＆G Central Research Institute. KF118 exhibited more vigorous growth characteristics in early stage than that of NC82, standard variety in Korea, while other characters were favorable to those of NC82, It is highly resistant to TMV and bacterial wilt(Ral-stonia solanacerum), and black shank(phytophthora parasitica var. nicotianae) is comparable to that of NC82. It should adapt well to the flue-cured production area, and can reduce premature flowering under unfavorable weather conditions. Yield of KF118 is 1 to 2% higher, and leaf quality is 4% higher than NC82. Fl hybrid, KF118, met acceptable standards for chemical and physical characteristics of cured leaf, and ranked high in good smoking taste by panel members in KT＆G.

• 천문학논총
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• 제32권1호
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• pp.317-319
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• 2017

We propose a cosmological survey to probe star formation and nuclear activity in galaxies at redshifts of z=2-4 by polycyclic aromatic hydrocarbon (PAH) features using the SPICA mid-infrared instrument (SMI) with a spectral resolution of R=20. We will cover a wavelength range of $20-36{\mu}$ that corresponds to z=2-4 for the PAH features (11.3, 7.7, and $6.2{\mu}$). The sensitivity will be $1{\times}10^{-19}W/m^2(5{\sigma})$ in case of a reference survey that covers 4 arcmin2 field in a one-hour observation. It corresponds to $L_{IR}=2{\times}10^{11}L_{\odot}$ at z=3 and will give us more than 10000 galaxies in a 450 hour survey.