• 대한지역사회영양학회지
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• 제21권3호
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• pp.256-264
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• 2016

Objectives: This study aimed to evaluate the diet and health status of elderly women according to the family type. Methods: A total of 307 elderly women participated in this study were divided into one of three groups according to their family type: residing with spouse (RSP; n=88), residing with son or daughter (RSD; n=119), and residing alone (RAL; n=100). Chisquare test was used to assess dietary habits and health status of the subjects by the family types. Results: Results demonstrated significant associations between eating regular meals, person preparing meals, coffee intake, and bone fracture experience and family type. Among the three groups, the RSP and RAL groups had a higher percentage for preparing meals by themselves (p<0.001) than the RSD group. The RAL group had a lower percentage for eating regular meals (p<0.01) but a higher percentage for bone fracture experience (p<0.05) than the other groups. There were no significant differences in monthly allowance, self-estimated health status, physical activity, exercise, drinking, and dietary habits such as frequency of consumption of dairy, beans, eggs, fish, meat, fruits, and vegetables among the three groups. Conclusions: The results showed that elderly women residing alone without a son, daughter, or spouse had more diet-related and health problems such as irregular meals and high bone fracture experience. These findings suggested that elderly women residing alone need more attention and support.

• 한국안광학회지
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• 제4권2호
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• pp.147-154
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• 1999

구안경(old spectacles)의 렌즈를 사용하고 안경테만 교환하는 경우의 조건에 부합되는 83 명을 대상으로 교환 동기, 테의 크기, 모양, 축의 연화, 양안시에 미치는 프리즘의 영향 등을 알아보았다. 안경테의 교환 동기는 80.4%가 파손이나 테부식에 의한 것이었고, 테의 모양은 타원형 계열이 62.4%, 사각형 계열이 37.6%를 차지하였다. 테의 크기는 구안경테(old frame)의 경우 $49{\Box}18$, 수직 거리가 33mm이었고 신안경테(new frame)가 $47{\Box}17$, 수직거리가 31mm로 작게 선택되는 것으로 나타났다. 신안경의 난시축의 변동 범위는 평균 +3.20~3.80이었다. 수평 방향의 프리즘의 영향을 RAL-RG 915기준에 의해 오차를 평가한 결과, 구안경에서 38.5%의 부적합이 신안경에선 42.2%로 증가하였다. 수직 방향에서 프리즘 변화 방향을 RAL-RG 915기준에 의해 오차를 평가해 보면 0.25${\leq}$1.00와 6.00D이상에서 적합 부적합률의 변동은 없었다. 그러나 1.00${\leq}$6.00에서는 부적합률이 구안경은 24.1%에서 신안경은 33.7%로 증가되었다.

• 한국안광학회지
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• 제9권1호
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• pp.19-27
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• 2004

안경을 착용한 고등학생 (17~19세) 남녀 150명을 대상으로 안경착용으로 인한 불편감과 안경의 관리 방법 등에 관한 설문지 조사를 실시하여 안경이 갖추어야 할 여러 요건 중에서 안경의 경사각, 정점간 거리, 광학중심 높이, 동공 간 거리등을 중심으로 하여 안경의 착용상태를 관찰해 다음과 같은 연구결과를 얻었다. 1. 안경착용자의 과거에 착용한 안경의 역학적 불편감으로는 코와 귀의 압박감이 34%, 안경의 흘러내림 30%, 시각적 불편감으로는 시력저하 30%, 안정피로 20%로 나타났다. 2. 현재 착용하고 있는 안경의 역학적 및 시각적 불편감은 압박감 50%, 흘러내림 30%, 칼라10%로 나타났다. 3. 비정시의 종류로 볼 때 안경착용자 중 근시가 56.7%, 나머지는 근시성 난시였으며 연구대상자의 60%는 양안 도수가 일치하지 않았다. 4. 착용안경의 경사각을 분석해 본 결과, 양안이 동일한 경우는 66.7%로 나타났고 평균 착용안경 경사각은 $10.07^{\circ}$로 나타났다. 5. 안경착용자의 정점간 거리를 분석한 결과, 양안의 정점간 거리가 통일한 경우는 65.3%로 나타났으며, 연구대상자의 정점간 거리는 평균 13.6 mm로 나타났다. 6. 연구대상자 150명의 단안에서 착용안경의 광학중심 높이와 착용자의 동공중심에서 대의 하부 rim까지의 수직거리가 RAL-RG915의 조제가공 허용오차범위 내에 있는 82안(54.6%)으로 나타났다. 7. 대상자 150명의 단안에서 착용 안경렌즈의 광학중심간 수평거리와 착용자의 동공중심간 거리가 RAL-RG915의 조제가공의 허용오차 범위 안에 86안(57.3%)로 나타났다.

• 센서학회지
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• 제18권1호
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• pp.33-41
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• 2009

A multilevel acoustic Fresnel lens (MAFL) for the ultrasonic imaging transducer of which center frequency is approximately 5.MHz was newly designed and fabricated. The phase level of the lens was 64, and the focal length and the aperture width were 30.mm and 11.mm, respectively. The characteristics of impulse response, acoustic field and imaging performance of the transducer attached the lens were compared with the transducer attached a conventional refraction type acoustic lens (RAL). The results show that the center frequency, the loop sensitivity, and the focal depth of the MAFL transducer were higher or larger than those of the RAL transducer by approximately 0.2.MHz, 1.4.dB, and 2.mm, respectively. Consequently, it was shown that the brighter acoustic images with higher lateral resolution and the increased imaging performance for deep targets can be obtained by using the MAFL transducer.

• 생명과학회지
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• 제24권5호
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• pp.588-593
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• 2014

본 논문은 RLIP76 단백질이 암, 종양 혈관 신생 및 그 치료에 미치는 중요성을 보고함에 있다. 암의 연구에 있어서, 종양의 혈관 신생을 억제시키는 인자와 영향을 끼치는 인자를 밝혀내는 것은 암의 억제와 치료를 위한 분자 생물학적 기전에 중대한 영향을 미친다. 최근 연구에서, RLIP76 단백질이 혈관 신생에 영향을 끼치는 역할을 발견하였다. RLIP76 제거 마우스의 종양은 일반 종양과 비교하여 혈관의 크기가 작으며, 가늘고, 그 혈관의 수가 적고 길이가 짧은 것으로 보고되고 있다. 게다가, Matrigel plugs을 이용한 혈관 신생 실험에서, RLIP76이 제거된 마우스에서는 혈관 생성이 억제 되었으나, 일반 마우스에서는 혈관이 생성되었다. 또한, 혈관세포를 이용한 in vitro 실험에 있어서, proliferation, migration 및 cord formation 모두가 RLIP76에 의해서 조절되었다. 일반적으로 RLIP76은 대부분의 인간 조직과 종양에서 발현되며, 약의 저항 기전 연구에 이용되고 있기도 한다. 또한, 이RLIP76은 small GTPase R-Ras와 상호작용을 통하여 세포 spreading 및 migration에 관여하고 있다. 이러한 결과는 RLIP76와 암 연구의 중요성을 보고하고 있으며, 혈관 세포의 기능의 기전 및 종양의 혈관 신생을 위한 RLIP76 단백질의 중요성을 알리고 있고, RLIP76의 추가적인 연구를 통하여 종양의 혈관 신생의 기전을 밝히는 것이 필요함을 제안하는 바이다.

• 천문학회지
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• 제51권3호
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• pp.49-63
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• 2018

We carry out a study of Sub-Millimeter Galaxies (SMGs) in the AKARI NEP-Deep field using the James Clerk Maxwell Telescope (JCMT) SCUBA-2 $850{\mu}m$ source catalog, released as part of the SCUBA-2 Cosmology Legacy Survey (S2CLS) program. The SCUBA-2 $850{\mu}m$ map has a root mean square (rms) noise of $1.2mJy\;beam^{-1}$ and covers an area of $0.60degree^2$. We find four SMGs which have counterparts to Herschel sources with spectroscopic redshifts in the literature. In addition, three dust obscured galaxies (DOGs) detected in Herschel bands are selected as a comparison sample. We derive IR luminosities of SMGs using the CIGALE code, which are similar to those of high redshift SMGs from previous studies. The contribution of AGN to the total IR luminosity in SMGs (2%-11%) is smaller than the lower limit for the one in DOGs (19%-35%), which is consistent with the expectation from the evolutionary scenario of massive galaxies. We search for SMGs in overdense regions as protocluster candidates and investigate four regions, including candidates around three DOGs. Finally, we argue that follow-up spectroscopic observation for the NEP-Deep field will provide crucial information to understand the role of SMGs in the evolution of massive galaxies.

• Journal of Periodontal and Implant Science
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• 제49권6호
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• pp.355-365
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• 2019

Purpose: The modified minimally invasive surgical technique (M-MIST) has been successfully employed to achieve periodontal regeneration. Platelet-rich fibrin (PRF) is known to enhance wound healing through the release of growth factors. This study aimed to observe the outcomes of periodontal surgery when M-MIST was used with or without PRF for the treatment of isolated intrabony defects. Methods: This randomized clinical trial was conducted on 36 systemically healthy patients, who had chronic periodontitis associated with a single-site buccal probing pocket depth (PPD) and clinical attachment level of ≥5 mm. Patients were randomly divided into 2 groups: the test group treated with M-MIST and PRF, and the control group treated with M-MIST alone. The primary periodontal parameters analyzed were PPD, relative attachment level (RAL), and relative gingival margin level. The radiographic parameters analyzed were change in alveolar crest position (C-ACP), linear bone growth (LBG), and percentage bone fill (%BF). Patients were followed up to 6 months post-surgery. Results: Intragroup comparisons at 3 and 6 months showed consistently significant improvements in PPD and RAL in both the groups. In intergroup comparisons, the improvement in PPD reduction, gain in RAL, and the level of the gingival margin was similar in both groups at 3 and 6 months of follow-up. Furthermore, an intergroup comparison of radiographic parameters also demonstrated similar improvements in C-ACP, LBG, and %BF at 6 months of follow-up. Conclusions: M-MIST with or without PRF yielded comparable periodontal tissue healing in terms of improvements in periodontal and radiographic parameters. Further investigation is required to confirm the beneficial effects of PRF with M-MIST.

• Journal of Periodontal and Implant Science
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• 제36권3호
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• pp.783-796
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• 2006

The periodontium is a topographically complex organ consisting of epithelial tissue, soft and mineralized tissues. Structures comprising the periodontium include the gingiva, periodontal ligament (PDL) , cementum and the alveolar bone. The molecular mechanism of differentiation in PDL fibroblast cells remain unclear. Amino acid transporters play an important role in supplying nutrition to normal and cancer cells and for cell proliferation. Amino acid transport system L is a major nutrient transport system responsible for the Na+-independent transport of neutral amino acids including several essential amino acids. The system L is divided into two major subgroups, the L-type amino acid transporter 1 (LAT1) and the L-type amino acid transporter 2 (LAT2). In this study, the expression pattern of amino acid transport system L was, therefore, investigated in the differentiation of PDL fibroblast cells. To determine the expression level of amino acid transport system L participating in intracellular transport of amino acids in the differentiation of PDL fibroblast cells, it was examined by RT-PCR, observation of cell morphology, Alizaline red-S staining and uptake analysis after inducing experimental differentiation in PDL fibroblast cells isolated from mouse molar teeth. The results are as follows. 1. The LAT1 mRNA was expressed in the early stage of PDL fibroblast cell differentiation. This expression level was gradually reduced by differentiation- inducing time and it was not observed after the late stage. 2. The expression level of LAT2 mRNA was increased in time-dependent manner during differentiation induction of PDL fibroblast cells. 3. There was no changes in. the expression level of 4F2hc mRNA, the cofactor of LAT1 and LAT2, during differentiation of PDL fibroblast cells. 4. The expression level of ALP mRNA was gradually increased and the expression level of Col I mRNA was decreased during differentiation of PDL fibroblast cells. 5. The L-leucine transport was reduced by time from the early stage to the late stage in PDL fibroblast cell differentiation. As the results, it is considered that among neutral ammo acid transport system L in differentiation of PDL fibroblast cells, the LATl has a key role in cell proliferation in the early stage of cell differentiation and the LAT2 has an important role in the late stage of cell differentiation for providing cells with neutral amino acids including several essential amino acids.

• 한국환경보건학회:학술대회논문집
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• 한국환경보건학회 2002년도 춘계 국제 학술대회
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• pp.49-51
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• 2002

To identify and evaluate the dichlorobenzidine(DCB)-DNA adducts in liver cell and bladder epithelial cells by $^{32}$ P-postlabeling and GC/MS-SIM, we orally exposed the dichlorobenzidine (20mg/kh body wt.,/day)to male sprague-dawley rats for 14 days. Two kinds of DCB-DNA adduct were found at the same site of thin layer chromatogram of $^{32}$ P-postlabeling method in liver cells and bladder epithelial cells. In liver cells, relative adduct labeling(RAL) $\times$ 10$^{12}$ of DCB-DNA adduct A1 were 34.1$\pm$3.71 and 69.9$\pm$5.02, that of adduct A2 were 74.1$\pm$10.1 and 105.1$\pm$10.1 on 10 and 14 days after treatment, respectively. And in bladder epithelia cells, RAL $\times$ 10$^{12}$ of DCB-DNA adduct A1 were 5.92$\pm$1.60 and 15.9$\pm$1.31, that of adduct A2 were 9,81$\pm$2.81 and 22.8$\pm$1.79 on 10 and 14 days after treatment, respectively. DCB metabolites formed DNA adducts were monoacetyl-dichlorobenzidine(acDCB) and diacety1-dichlorobenzidine(di-acDCB), which was identify by gas chromatography/mass spectrometry-scan ionization mode(GC/MS-SIM), along with hydrolysis, extraction and TFA(trifluoroacetyl anhyride) derivatization with DCB-DNA adducts isolated from live cells and bladder epithelial cells. The base peak of acDCB were 252 and 294 m/z, and that of di-acDCB were 252, 294 and 336 m/z. In conclusion, the exposed DCB formed two kinds of DCB-DNA adduct, the proximate materials of that were acDCB and di-acDCB in liver and bladder epithlial cells. And the above GC/MS-SIM method was found the DCB-DNA adducts could be monitoring by gas chromatography.

• 한국안광학회지
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• 제3권1호
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• pp.189-199
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• 1998

완성안경의 광학적 허용요차에 대한 system을 안경처방서 작성시 환경, 주시거리, 하방 주시각, 테의 늘어남, 정정간 거리(VD), 토릭렌즈의 축, 렌즈의 기울기 등의 누적 오차 합 형태로 만들었다. 굴절력(D)에 따른 $O{\cdot}C$의 허용치 크기(T) 관계를 $T=T_0e^{-aD}$으로 주어지고 여기서, $T_0$는 굴절력이 0인 평면렌즈의 허용치 크기이고, ${\alpha}$는 허용치 factor이다. RAL-915에 대응하는 새로운 형태의 허용오차를 적용하는 경우, 허용오차가 큰 방향에 대해서는 허용치 factor ${\alpha}$는 $0.166(T_0=5.90)$이고, 허용오차가 작은 방향에 대해서는 허용치 factor ${\alpha}$는 $0.166(T_0=2.95)$ 값을 갖는다.