| 1 |
Lee, S., Wurtzel, J. G., Singhal, S. S., Awasthi, S. and Goldfinger, L. E. 2012. RALBP1/RLIP76 depletion in mice suppresses tumor growth by inhibiting tumor neovascularization. Cancer Res 72, 5165-5173.
DOI
ScienceOn
|
| 2 |
Singhal, S. S., Yadav, S., Drake, K., Singhal, J. and Awasthi, S. 2008. Hsf-1 and POB1 induce drug sensitivity and apoptosis by inhibiting Ralbp1. J Biol Chem 283, 19714-19729.
DOI
ScienceOn
|
| 3 |
Jullien-Flores, V., Dorseuil, O., Romero, F., Letourneur, F., Saragosti, S., Berger, R., Tavitian, A., Gacon, G. and Camonis, J. H. 1995. Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity. J Biol Chem 270, 22473-22477.
DOI
ScienceOn
|
| 4 |
Komatsu, M. and Ruoslahti, E. 2005. R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis. Nat Med 11, 1346-1350.
DOI
ScienceOn
|
| 5 |
LaBelle, E. F., Singh, S. V., Srivastava, S. K. and Awasthi, Y. C. 1986. Dinitrophenyl glutathione efflux from human erythrocytes is primary active ATP-dependent transport. Biochem J 238, 443-449.
DOI
|
| 6 |
Leake, K., Singhal, J., Nagaprashantha, L. D., Awasthi, S. and Singhal, S. S. 2012. RLIP76 regulates PI3K/Akt signaling and chemo-radiotherapy resistance in pancreatic cancer. PLoS One 7, e34582.
DOI
|
| 7 |
Matarrese, P., Colasanti, T., Ascione, B., Margutti, P., Franconi, F., Alessandri, C., Conti, F., Riccieri, V., Rosano, G., Ortona, E. and Malorni, W. 2011. Gender disparity in susceptibility to oxidative stress and apoptosis induced by autoantibodies specific to RLIP76 in vascular cells. Antioxid Redox Signal 15, 2825-2836.
DOI
ScienceOn
|
| 8 |
Downey, C. M., Singla, A. K., Villemaire, M. L., Buie, H. R., Boyd, S. K. and Jirik, F. R. 2012. Quantitative ex-vivo micro-computed tomographic imaging of blood vessels and necrotic regions within tumors. PLoS One 7, e41685.
DOI
|
| 9 |
Bauer, B., Mirey, G., Vetter, I. R., Garcia-Ranea, J. A., Valencia, A., Wittinghofer, A., Camonis, J. H. and Cool, R. H. 1999. Effector recognition by the small GTP-binding proteins Ras and Ral. J Biol Chem 274, 17763-17770.
DOI
|
| 10 |
Borst, P., Evers, R., Kool, M. and Wijnholds, J. 2000. A family of drug transporters: the multidrug resistance-associated proteins. J Natl Cancer Inst 92, 1295-1302.
DOI
ScienceOn
|
| 11 |
Goldfinger, L. E., Ptak, C., Jeffery, E. D., Shabanowitz, J., Han, J., Haling, J. R., Sherman, N. E., Fox, J. W., Hunt, D. F. and Ginsberg, M. H. 2007. An experimentally derived database of candidate Ras-interacting proteins. J Proteome Res 6, 1806-1811.
DOI
ScienceOn
|
| 12 |
Heitzer, T., Schlinzig, T., Krohn, K., Meinertz, T. and Munzel, T. 2001. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 104, 2673-2678.
DOI
ScienceOn
|
| 13 |
Awasthi, S., Singhal, S. S., Awasthi, Y. C., Martin, B., Woo, J. H., Cunningham, C. C. and Frankel, A. E. 2008. RLIP76 and Cancer. Clin Cancer Res 14, 4372-4377.
DOI
ScienceOn
|
| 14 |
Ishikawa, T. 1992. The ATP-dependent glutathione S-conjugate export pump. Trends Biochem Sci 17, 463-468.
DOI
ScienceOn
|
| 15 |
Jedlitschky, G., Leier, I., Buchholz, U., Barnouin, K., Kurz, G. and Keppler, D. 1996. Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res 56, 988-994.
|
| 16 |
Awasthi, S., Singhal, S. S., Srivastava, S. K., Zimniak, P., Bajpai, K. K., Saxena, M., Sharma, R., Ziller, S. A., Frenkel, E. P. and Singh, S. V. 1994. Adenosine triphosphate-dependent transport of doxorubicin, daunomycin, and vinblastine in human tissues by a mechanism distinct from the P-glycoprotein. J Clin Invest 939, 58-965.
|
| 17 |
Ambudkar, S. V., Dey, S., Hrycyna, C. A., Ramachandra, M., Pastan, I. and Gottesman, M. M. 1999. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol 39, 361-398.
DOI
ScienceOn
|
| 18 |
Awasthi, S., Sharma, R., Singhal, S. S., Zimniak, P. and Awasthi, Y. C. 2002. RLIP76, a novel transporter catalyzing ATP-dependent efflux of xenobiotics. Drug Metab Dispos 30, 1300-1310.
DOI
ScienceOn
|
| 19 |
Awasthi, Y. C., Singhal, S. S., Gupta, S., Ahmad, H., Zimniak, P., Radominska, A., Lester, R. and Sharma, R. 1991. Purification and characterization of an ATPase from human liver which catalyzes ATP hydrolysis in the presence of the conjugates of bilirubin bile acids and glutathione. Biochem Biophys Res Commun 175, 1090-1096.
DOI
ScienceOn
|
| 20 |
Awasthi, Y. C., Ansari, G. A. and Awasthi, S. 2005. Regulation of 4-hydroxynonenal mediated signaling by glutathione S-transferases. Methods Enzymol 401, 379-407.
DOI
ScienceOn
|
| 21 |
Awasthi, Y. C., Chaudhary, P., Vatsyayan, R., Sharma, A., Awasthi, S. and Sharma, R. 2009. Physiological and pharmacological significance of glutathione-conjugate transport. J Toxicol Environ Health B Crit Rev 12, 540-551.
DOI
ScienceOn
|
| 22 |
Walls, J. R., Coultas, L., Rossant, J. and Henkelman, R. M. 2008. Three-dimensional analysis of vascular development in the mouse embryo. PLoS One 3, e2853.
DOI
ScienceOn
|
| 23 |
Srivastava, S. K., Hu, X., Xia, H., Bleicher, R. J., Zaren, H. A., Orchard, J. L., Awasthi, S. and Singh, S. V. 1998. ATP-dependent transport of glutathione conjugate of 7beta, 8alpha-dihydroxy-9alpha,10alpha-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene in murine hepatic canalicular plasma membrane vesicles. Biochem J 332, 799-805.
DOI
|
| 24 |
Stuckler, D., Singhal, J., Singhal, S. S., Yadav, S., Awasthi, Y. C. and Awasthi, S. 2005. RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer. Cancer Res 65, 991-998.
|
| 25 |
Vatsyayan, R., Lelsani, P. C., Awasthi, S. and Singhal, S. S. 2010. RLIP76: a versatile transporter and an emerging target for cancer therapy. Biochem Pharmacol 79, 1699-1705.
DOI
ScienceOn
|
| 26 |
Yang, J., Yu, L. X., Rennie, M. Y., Sled, J. G. and Henkelman, R. M. 2010. Comparative structural and hemodynamic analysis of vascular trees. Am J Physiol Heart Circ Physiol 298, H1249-1259.
DOI
ScienceOn
|
| 27 |
Singhal, S. S., Yadav, S., Roth, C. and Singhal, J. 2009. RLIP76: a novel glutathione-conjugate and multi-drug transporter. Biochem Pharmacol 77, 761-769.
DOI
ScienceOn
|
| 28 |
Shojaei, F., Wu, X., Zhong, C., Yu, L., Liang, X. H., Yao, J., Blanchard, D., Bais, C., Peale, F. V., van Bruggen, N., Ho, C., Ross, J., Tan, M., Carano, R. A., Meng, Y. G. and Ferrara, N. 2007. Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Nature 450, 825-831.
DOI
ScienceOn
|
| 29 |
Singhal, S. S., Yadav, S., Singhal, J., Zajac, E., Awasthi, Y. C. and Awasthi, S. 2005. Depletion of RLIP76 sensitizes lung cancer cells to doxorubicin. Biochem Pharmacol 70, 481-488.
DOI
ScienceOn
|
| 30 |
Singhal, S. S., Sharma, R., Gupta, S., Ahmad, H., Zimniak, P., Radominska, A., Lester, R. and Awasthi, Y. C. 1991. The anionic conjugates of bilirubin and bile acids stimulate ATP hydrolysis by S-(dinitrophenyl) glutathione ATPase of human erythrocyte. FEBS Lett 281, 255-257.
DOI
ScienceOn
|
| 31 |
Singhal, S. S., Awasthi, Y. C. and Awasthi, S. 2006. Regression of melanoma in a murine model by RLIP76 depletion. Cancer Res 66, 2354-2360.
DOI
ScienceOn
|
| 32 |
Singhal, S. S., Roth, C., Leake, K., Singhal, J., Yadav, S. and Awasthi, S. 2009. Regression of prostate cancer xenografts by RLIP76 depletion. Biochem Pharmacol 77, 1074-1083.
DOI
ScienceOn
|
| 33 |
Singhal, S. S., Singhal, J., Nair, M. P., Lacko, A. G., Awasthi, Y. C. and Awasthi, S. 2007 Doxorubicin transport by RALBP1 and ABCG2 in lung and breast cancer. Int J Oncol 30, 717-725.
|
| 34 |
Singhal, S. S., Singhal, J., Yadav, S., Dwivedi, S., Boor, P. J., Awasthi, Y. C. and Awasthi, S. 2007. Regression of lung and colon cancer xenografts by depleting or inhibiting RLIP76 (Ral-binding protein 1). Cancer Res 67, 4382-4389.
DOI
ScienceOn
|
| 35 |
Singhal, S. S., Singhal, J., Yadav, S., Sahu, M., Awasthi, Y. C. and Awasthi, S. 2009. RLIP76: a target for kidney cancer therapy. Cancer Res 69, 4244-4251.
DOI
ScienceOn
|
| 36 |
Sharma, R., Gupta, S., Singh, S. V., Medh, R. D., Ahmad, H., LaBelle, E. F. and Awasthi, Y. C. 1990. Purification and characterization of dinitrophenylglutathione ATPase of human erythrocytes and its expression in other tissues. Biochem Biophys Res Commun 171, 155-161.
DOI
ScienceOn
|
| 37 |
Saxena, M., Singhal, S. S., Awasthi, S., Singh, S. V., Labelle, E. F., Zimniak, P. and Awasthi, Y. C. 1992. Dinitrophenyl S-glutathione ATPase purified from human muscle catalyzes ATP hydrolysis in the presence of leukotrienes. Arch Biochem Biophys 298, 231-237.
DOI
ScienceOn
|
| 38 |
Mollberg, N. M., Steinert, G., Aigner, M., Hamm, A., Lin, F. J., Elbers, H., Reissfelder, C., Weitz, J., Buchler, M. W. and Koch, M. 2012. Overexpression of RalBP1 in colorectal cancer is an independent predictor of poor survival and early tumor relapse. Cancer Biol Ther 13, 694-700.
DOI
ScienceOn
|
| 39 |
Nakashima, S., Morinaka, K., Koyama, S., Ikeda, M., Kishida, M., Okawa, K., Iwamatsu, A., Kishida, S. and Kikuchi, A. 1999. Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors. EMBO J 18, 3629-3642.
DOI
ScienceOn
|
| 40 |
Sharma, R., Singhal, S. S., Wickramarachchi, D., Awasthi, Y. C. and Awasthi, S. 2004. RLIP76-mediated transport of leukotriene C4 (LTC4) in cancer cells: implications in drug resistance. Int J Cancer 112, 934-942.
DOI
ScienceOn
|
| 41 |
Awasthi, S., Singhal, S. S., Yadav, S., Singhal, J., Drake, K., Nadkar, A., Zajac, E., Wickramarachchi, D., Rowe, N., Yacoub, A., Boor, P., Dwivedi, S., Dent, P., Jarman, W. E., John, B. and Awasthi, Y. C. 2005. RLIP76 is a major determinant of radiation sensitivity. Cancer Res 65, 6022-6028.
DOI
ScienceOn
|
| 42 |
Singhal, S. S., Wickramarachchi, D., Yadav, S., Singhal, J., Leake, K., Vatsyayan, R., Chaudhary, P., Lelsani, P., Suzuki, S., Yang, S., Awasthi, Y. C. and Awasthi, S. 2011. Glutathione-conjugate transport by RLIP76 is required for clathrin-dependent endocytosis and chemical carcinogenesis. Mol Cancer Ther 10, 16-28.
|
| 43 |
Savai, R., Langheinrich, A. C., Schermuly, R. T., Pullamsetti, S. S., Dumitrascu, R., Traupe, H., Rau, W. S., Seeger, W., Grimminger, F. and Banat, G. A. 2009. Evaluation of angiogenesis using micro-computed tomography in a xenograft mouse model of lung cancer. Neoplasia 11, 48-56.
DOI
|
| 44 |
Sharma, R., Singhal, S. S., Cheng, J., Yang, Y., Sharma, A., Zimniak, P., Awasthi, S. and Awasthi, Y. C. 2001. RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes. Arch Biochem Biophys 391, 171-179.
DOI
ScienceOn
|
| 45 |
Margutti, P., Matarrese, P., Conti, F., Colasanti, T., Delunardo, F., Capozzi, A., Garofalo, T., Profumo, E., Rigano, R., Siracusano, A., Alessandri, C., Salvati, B., Valesini, G., Malorni, W., Sorice, M. and Ortona, E. 2008. Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis. Blood 111, 4559-4570.
DOI
ScienceOn
|
| 46 |
Cheng, J. Z., Sharma, R., Yang, Y., Singhal, S. S., Sharma, A., Saini, M. K., Singh, S. V., Zimniak, P., Awasthi, S. and Awasthi, Y. C. 2001. Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress. J Biol Chem 276, 41213-41223.
DOI
ScienceOn
|
webmaster
