• Journal of radiological science and technology
• /
• v.41 no.6
• /
• pp.627-635
• /
• 2018

The purpose of this study was to compare the job stress, job satisfaction, turnover intention, and job performance feelings of radiological technologists, physical therapists, and medical laboratory technologists working at university hospitals and general hospitals. The subjects were 114 general practitioners and 217 university hospital workers who are engaged in occupations of radiological technologists, physical therapists, and medical laboratory technologists in the age groups 20-50 years living in Incheon Metropolitan City. Data collection was conducted from April 1, 2017 to April 30, and data analysis was performed using the SPSS/WIN 23 statistical program. There were statistically significant difference in the job stress of medical technician by age, marriage, occupation, hospital size, position, parenting form, employment type, and lunch break. Job stress by occupation was highest in medical laboratory technologists, followed by radiological technologists and physical therapists. Job satisfaction was the highest among physical therapists. followed by radiological technologists and medical laboratory technologists. There were significant differences in age, occupation, parenting form, type of employment, and lunch break according to demographic characteristics. In order to reduce the job stress and job satisfaction of the medical technician working at the hospital, the development of the job environment should be sought and the hospital should also be removed from the authoritarian management system.

• Nuclear Engineering and Technology
• /
• v.55 no.9
• /
• pp.3417-3422
• /
• 2023

Recently, as the clinically positive biological effects of ultra-high dose rate (UHDR) radiation beams have been revealed, interest in flash radiation therapy has increased. Generally, FLASH preclinical experiments are performed using UHDR electron beams generated by linear accelerators. Real-time monitoring of UHDR beams is required to deliver the correct dose to a sample. However, it is difficult to use typical transmission-type ionization chambers for primary beam monitoring because there is no suitable electrometer capable of reading high pulsed currents, and collection efficiency is drastically reduced in pulsed radiation beams with ultra-high doses. In this study, a monitoring method using bremsstrahlung photons generated by irradiation devices and a water phantom was proposed. Charges collected in an ionization chamber located at the back of a water phantom were analyzed using the bremsstrahlung tail on electron depth dose curves obtained using radiochromic films. The dose conversion factor for converting a monitored charge into a delivered dose was determined analytically for the Advanced Markus® chamber and compared with experimentally determined values. It is anticipated that the method proposed in this study can be useful for monitoring sample doses in UHDR electron beam irradiation.

• Journal of the Korean Society of Radiology
• /
• v.10 no.6
• /
• pp.411-418
• /
• 2016

This study presented a mediation strategy of admittance quota of four year and three year colleges raising radiology technicians by investigating the demand and supply related literature for Radiological Technologists, a type of health and medical services personnel. Oh Yeong-ho et al.'s study on mid and long term supply system for health and medical services personnel resources, excess supply of 1,134~2,052 Radiological Technologists in 2015 was predicted and excess supply of 12,632~14,196 Radiological Technologists are to be expected in 2030. To settle excess supply of Radiological Technologists, Supernumerary quota over the entrance students of institutions raising Radiological Technologists should be less than 5% to reduce applicants for Radiological Technologists to be 308 people, reduce 387 applicants for radiology technicians every year by unifying three year colleges raising Radiological Technologists with four year colleges into education period unification, evaluate education conditions of colleges to restrict those colleges lacking the minimum requirements from getting eligibility for take the examination for Radiological Technologists by establishing tentatively 'Korean Institute of Radiologic Education and Evaluation.' For this, it is necessary to obtain cooperation from health and medical services personnel organizations in pertinent fields as well as related organizations of Radiological Technologists.

• Journal of radiological science and technology
• /
• v.34 no.2
• /
• pp.123-129
• /
• 2011

This study aimed at 1) investigating the perception, knowledge and behaviors of radiological technologists on radiation defence and 2) preparing plans to reduce the unnecessary radiation dose on practician, patients and their caretakers. For data collection, a structured questionnaire was used to survey 225 radiological technologists living in downtown Busan. To analyze the collected data, SPSS/PC+ Win 13 version was used. For verification of differences between groups, one-way ANOVA was conducted. In addition, multiple regression analysis was conducted to analyze the impact of general variables (knowledge, education, age and length of service) in radiation safety management perspective. No differences were found in terms of the knowledge on radiation/radioactivity according to educational background, age and length of service. In the perspective of radiation safety management, the highest figures were found among those in their 40s and higher and those with the education of college graduation and higher. As for the correlation between radiation safety management and knowledge on radiation/radioactivity, positive correlations were found in all cases. In addition, analysis on the impact of general variables in radiation safety management perspective indicated that the perception on radiation safety management was higher as the level of knowledge on radiation/radioactivity was higher. The correct radiation/radioactivity management through practician training was necessary to reduce radiation dose on radiological technologists and patients.

• Molecules and Cells
• /
• v.38 no.4
• /
• pp.327-335
• /
• 2015

Piperlongumine, a natural alkaloid isolated from the long pepper, selectively increases reactive oxygen species production and apoptotic cell death in cancer cells but not in normal cells. However, the molecular mechanism underlying piperlongumine-induced selective killing of cancer cells remains unclear. In the present study, we observed that human breast cancer MCF-7 cells are sensitive to piperlongumine-induced apoptosis relative to human MCF-10A breast epithelial cells. Interestingly, this opposing effect of piperlongumine appears to be mediated by heme oxygenase-1 (HO-1). Piperlongumine upregulated HO-1 expression through the activation of nuclear factor-erythroid-2-related factor-2 (Nrf2) signaling in both MCF-7 and MCF-10A cells. However, knockdown of HO-1 expression and pharmacological inhibition of its activity abolished the ability of piperlongumine to induce apoptosis in MCF-7 cells, whereas those promoted apoptosis in MCF-10A cells, indicating that HO-1 has anti-tumor functions in cancer cells but cytoprotective functions in normal cells. Moreover, it was found that piperlongumine-induced Nrf2 activation, HO-1 expression and cancer cell apoptosis are not dependent on the generation of reactive oxygen species. Instead, piperlongumine, which bears electrophilic ${\alpha},{\beta}$-unsaturated carbonyl groups, appears to inactivate Kelch-like ECH-associated protein-1 (Keap1) through thiol modification, thereby activating the Nrf2/HO-1 pathway and subsequently upregulating HO-1 expression, which accounts for piperlongumine-induced apoptosis in cancer cells. Taken together, these findings suggest that direct interaction of piperlongumine with Keap1 leads to the upregulation of Nrf2-mediated HO-1 expression, and HO-1 determines the differential response of breast normal cells and cancer cells to piperlongumine.

• Journal of the Society of Disaster Information
• /
• v.20 no.3
• /
• pp.573-583
• /
• 2024

Purpose: This study predicted the flow of chemical, biological, and radiological materials in chemical, biological, and radiological defense facilities within the base during a chemical, biological, and radiological attack based on the conditions of the facility before the existing improvement, analyzed the flow of pollutants and the human impact of toxic substances, and identified the occurrence of leakage. Method: Assuming that the simple chemical, biological, and radiological defense facility improvement plan, which reflects the characteristics of the building, has been improved to the facility standard, the flow of chemical, biological, and radiological materials in the chemical, biological, and radiological defense facility within the base was predicted in the event of a chemical, biological, and radiological attack under the same conditions, and the flow of contaminants and the impact on occupants by toxic substances were analyzed to determine spatial safety. Result: In the case of Plan 1, it was found that leakage occurred after approximately 250 seconds in spaces where existing flat-panel chemical, biological, and radiological defense facilities were not installed. In the cases of Plans 2 and 3, it was found that leakage occurred in spaces where existing flat-panel chemical, biological, and radiological defense facilities were not installed. Conclusion: n the case of plans 1, 2, and 3, it was found that airtightness was maintained because no leakage occurred in the improved plane. In the case of plan 4, airtightness was not maintained due to leakage in the space where the existing plane simple chemical, biological, and radiological protection facilities were not installed.

• Proceedings of the Korean Society of Medical Physics Conference
• /
• 2006.08a
• /
• pp.136-136
• /
• 2006

• Proceedings of the Korean Society of Medical Physics Conference
• /
• 2006.08a
• /
• pp.28-28
• /
• 2006

• 한국생물공학회:학술대회논문집
• /
• 2005.10a
• /
• pp.806-807
• /
• 2005

• Proceedings of the Korean Society of Medical Physics Conference
• /
• 2006.08a
• /
• pp.46-46
• /
• 2006