• Title/Summary/Keyword: Radiologic response

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Systemic Nocardiosis Mimicking Disease Flare-up after Discontinuation of Gefitinib in a Patient with EGFR-Mutant Lung Cancer

  • Choi, Mihong;Lee, Youngjoo;Hwang, Sang Hyun;Lee, Jin Soo
    • Tuberculosis and Respiratory Diseases
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    • v.77 no.6
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    • pp.271-273
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    • 2014
  • Disease flare-up after discontinuing epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) has been considered as a critical issue in lung cancer patients who have experienced radiologic progression after showing initial durable response. This is a case of systemic nocardiosis that occurred after chronic steroid use for radionecrosis from stereotactic radiosurgery. It was initially thought as a disease flare-up after stopping EGFR-TKI.

- Development of Digital Fluoroscopic Image Recording System for Customer Safety - (고객 안전을 위한 디지털 방사선장치(DRF)의 투시영상기록장치 개발)

  • Rhim Jae Dong;Kang Kyong Sik
    • Journal of the Korea Safety Management & Science
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    • v.6 no.3
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    • pp.303-309
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    • 2004
  • Many system devices for fluoroscopic and general X-ray studies in diagnostic radiographic system have been being changed from analog mode to digital mode. In addition, among diagnostic imaging and radiologic examinations, fluoroscopic studies that requires functional diagnosis is being widely used. The video recording method of fluoroscopic studies has been useful in functional image diagnosis and dynamic image observation, but the utility of its image quality is being reduced because of limitation in setting play segments of the video player, inconvenience of play, difficulties in preserving reproduced images, the change of image quality, etc. In order to complement these shortages, it is necessary to facilitate access to patient diagnosis information such as storing, editing and sharing functional diagnosis images in response to the trend of the digitalization of digital radiographic & fluoroscopic system(DRF). Thus this study designed and implemented a device of storing functional dynamic images real time using a computer rather than existing video recording, aiming at contribution to functional image diagnosis.

Allergic Bronchopulmonary Aspergillosis Presenting as Recurrent Mass-like Consolidation

  • Choe, Yeong Hun
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.2
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    • pp.133-136
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    • 2015
  • Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitive disease showing various radiographic and clinical manifestations. Its clinical course has not been fully understood. Here I describe a case of a 23-year-old immunocompetent man with frequently relapsing ABPA. He was asthmatic. He visited our hospital because of a chronic cough. Laboratory examination showed eosinophilia with increased total and Aspergillus-specific IgE as well as positive skin reaction to Aspergillus fumigatus. Radiologic feature was a dense consolidation. Histology showed organizing pneumonia with eosinophilic infiltration. On the diagnosis of ABPA, he was treated with systemic steroid and itraconazole. Although treatment response was excellent, he suffered from recurrent ABPA three times thereafter in the form of fleeting mass-like consolidation.

RWM Filter Adopting Fuzzy Cluster (퍼지 클러스터를 적용한 RWM 필터)

  • Lee, Bong-Young;Yun, Kwang-Ho;Lee, Hoo-Min;Nam, Moon-Hyon
    • Proceedings of the KIEE Conference
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    • 2001.07d
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    • pp.2078-2080
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    • 2001
  • 본 논문은 기존의 가중 메디안 필터에 음의 가중치를 갖는 recursive weighted median(RWM) 필터 구조를 소개하고자 한다. 이는 연산과정에 퍼지 클러스터를 적용하여 또 다른 구조의 RWM 필터를 제안하였다. 제안된 RWM 필터는 infinte impulse response(IIR) 선형 필터의 부류로 상사되는 것으로서 기존의 선형 IIR 필터와는 달리 강건한 대역 또는 고역통과 필터의 특성 뿐만 아니라 피드백 되어진 계수 값에 상관없이 항상 BIBO 시스템에서의 안정성과 잡음에 강건한 특성을 나타낸다. 특히 퍼지 클러스터를 적용하여 중앙값 주변의 값을 적절히 취함으로서 신뢰성과 보다 빠른 연산속도의 성능을 여러 다른 구조의 필터들과 성능 비교 실험을 통해 입증하였다.

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Pelvic Actinomycosis Mimicking Malignancy of the Uterus: a Case Report

  • Shin, Dahye;Hwang, Jiyoung;Hong, Seong Sook;Lee, Eun Ji;Kim, Yon Hee
    • Investigative Magnetic Resonance Imaging
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    • v.23 no.2
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    • pp.136-141
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    • 2019
  • Pelvic actinomycosis is an uncommon infectious disease. It induces a chronic, suppurative illness characterized by an infiltrative and granulomatous response and, thus, the clinical and radiologic findings may mimic other inflammatory and neoplastic conditions. A 56-year-old female with a long-standing intrauterine device was diagnosed with pelvic actinomycosis manifesting as a large uterine mass with locally infiltrative spread into surrounding tissue that mimicked uterine malignancy. Actinomyces israelii infection was confirmed with a surgical specimen, and the patient was treated with antibiotic medication. Pelvic actinomycosis must be included in the differential diagnoses of patients with an infiltrative pelvic mass extending across tissue planes or in patients with findings of multiple microabscesses, particularly in a patient with an intrauterine device, even the lesion primarily involves the uterus.

A Case of Klatskin Tumor Showing Slow Progression

  • Min Kyu Kang;Kook Hyun Kim;Joon Hyuk Choi;Tae Nyeun Kim
    • Journal of Digestive Cancer Research
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    • v.5 no.1
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    • pp.55-57
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    • 2017
  • A 64-year-old man was admitted due to jaundice for 2 weeks. Radiologic findings revealed biliary stricture at the hepatic hilum with intrahepatic duct dilation suggesting Bismuth type IV Klatskin tumor. Jaundice improved spontaneously several days after hospitalization. Surgical treatment was considered but he only wanted to observe without specific treatment. Ten months later, he was re-admitted due to the recurrence of jaundice. Computed tomography (CT) showed no significant difference compared to previous results. Serum cancer antigen 19-9 and Immunoglobulin G4 were normal. Endoscopic forcep biopsy during endoscopic retrograde cholagiopancreatography (ERCP) revealed chronic inflammation. After steroid use under possible diagnosis of IgG4 related cholangiopathy, biliary stricture improved slightly. Four years later, he was hospitalized with the occurrence of acute cholangitis. Endoscopic retrograde biliary drainage was performed following endobiliary forcep biopsy. Pathology revealed well-differentiated adenocarcinoma at this time. Combined chemotherapy based on gemcitabine and cisplatin was performed. Six months later, CT revealed partial response.

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Study of the Respiratory Monitoring System by Using the MEMS Acceleration Sensor (MEMS 가속도 센서를 이용한 환자 호흡동작 모니터링 체계 연구)

  • Sung, Jiwon;Yoon, Myonggeun;Chung, Weon Kuu;Kim, Dong Wook;Shin, Dong Oh
    • Progress in Medical Physics
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    • v.24 no.1
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    • pp.61-67
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    • 2013
  • In this study, we developed and evaluated the patient respiration training method which can help to avoid the problems for the limitation of RGRT applicable patient cases. By using the MEMS (micro-electro-mechanical-system) acceleration sensor, we measured movement of motion phantom. We had compared the response of MEMS with commercially introduced real time patient monitoring (RPM) system. We measured the response of the MEMS with 1 dimensional motion phantom movement for 2.5, 3.0, 3.5 second of period and the 2.0, 3.0, 4.0 cm of the amplitudes. The measured period error of the MEMS system was 0.6~6.0% compared with measured period using RPM system. We found that the shape of MEMS signals were similar with RPM system. From this study, we found the possibility of MEMS as patient training system.

Prognostic value of pretreatment 18F-FDG PET-CT in radiotherapy for patients with hepatocellular carcinoma

  • Jo, In Young;Son, Seok-Hyun;Kim, Myungsoo;Sung, Soo Yoon;Won, Yong Kyun;Kang, Hye Jin;Lee, So Jung;Chung, Yong-An;Oh, Jin Kyoung;Kay, Chul-Seung
    • Radiation Oncology Journal
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    • v.33 no.3
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    • pp.179-187
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    • 2015
  • Purpose: The purpose of this study was to investigate the predictable value of pretreatment $^{18}F$-fluorodeoxyglucose positron emission tomography-computed tomography ($^{18}F$-FDG PET-CT) in radiotherapy (RT) for patients with hepatocellular carcinoma (HCC) or portal vein tumor thrombosis (PVTT). Materials and Methods: We conducted a retrospective analysis of 36 stage I-IV HCC patients treated with RT. $^{18}F$-FDG PET-CT was performed before RT. Treatment target was determined HCC or PVTT lesions by treatment aim. They were irradiated at a median prescription dose of 50 Gy. The response was evaluated within 3 months after completion of RT using the Response Evaluation Criteria in Solid Tumors (RECIST). Response rate, overall survival (OS), and the pattern of failure (POF) were analyzed. Results: The response rate was 61.1%. The statistically significant prognostic factor affecting response in RT field was maximal standardized uptake value (maxSUV) only. The high SUV group (maxSUV ${\geq}5.1$) showed the better radiologic response than the low SUV group (maxSUV < 5.1). The median OS were 996.0 days in definitive group and 144.0 days in palliative group. Factors affecting OS were the %reduction of alpha-fetoprotein (AFP) level in the definitive group and Child-Pugh class in the palliative group. To predict the POF, maxSUV based on the cutoff value of 5.1 was the only significant factor in distant metastasis group. Conclusion: The results of this study suggest that the maxSUV of $^{18}F$-FDG PET-CT may be a prognostic factor for treatment outcome and the POF after RT. A %reduction of AFP level and Child-Pugh class could be used to predict OS in HCC.

Clinical Application and Limitations of Myeloma Response Assessment and Diagnosis System (MY-RADS) (골수종 반응평가와 진단체계의 임상적용 및 제한점)

  • Dong Kyun Kim;Sung-Soo Park; Joon-Yong Jung
    • Journal of the Korean Society of Radiology
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    • v.84 no.1
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    • pp.51-74
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    • 2023
  • Multiple myeloma, which is a proliferative disease of plasma cells that originate from a single clone, is the second most common hematologic malignancy following non-Hodgkin lymphoma. In the past, its diagnosis was made based on clinical findings (so-called "CRAB") and a skeletal survey using radiographs. However, since the implementation of the International Myeloma Working Group's revised guideline regarding the radiologic diagnosis of multiple myeloma, whole-body (WB) MRI has emerged to play a central role in the early diagnosis of multiple myeloma. Diffusion-weighted imaging and fat quantification using Dixon methods enable treatment response assessment by MRI. In keeping with the trend, a multi-institutional and multidisciplinary consensus for standardized image acquisition and reporting known as the Myeloma Response Assessment and Diagnostic System (MY-RADS) has recently been proposed. This review aims to describe the clinical application of WB-MRI based on MY-RADS in multiple myeloma, discuss its limitations, and suggest future directions for improvement.

Development of Hazardous Objects Detection Technology based on Metal/Non-Metal Detector (금속/비금속 복합센서기반 위험물 탐지기술 개발)

  • Yoo, Dong-Su;Kim, Seok-Hwan;Lee, Jeong-Yeob;Lee, Seok-Jae
    • Journal of Institute of Control, Robotics and Systems
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    • v.20 no.2
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    • pp.120-125
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    • 2014
  • Conventional handheld metal detectors use a single induction coil to detect the metallic parts of explosive objects, and the detector generates an acoustic signal from its magnetic response to a metallic object so that an operator can confirm the existence of mines. Though metal detectors have very useful detection mechanisms to find mines, it is easy to cause a high false alarm ratio due to the detection of non-explosive metallic items such as cans, nails and other pieces of metal, etc. Also, because of the physical characteristic of a metal detector it is hard to detect non-metallic objects such as mines made of wood or plastic. Furthermore, the operator must move it to the left and right slowly and repeatedly to attain enough sensor signals to confirm the existence of mines using only a monotonous acoustic signal. To resolve the disadvantages of handheld detectors, many new approaches have been attempted, such as an arrayed detector and a visualization algorithm based on metal/non-metal sensor. In this paper, we introduce a visualization algorithm with a metal/non-metal complex sensor, an arrayed metal/non-metal sensor and the their testing and evaluation.