• The Korean Journal of Nuclear Medicine
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• v.26 no.1
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• pp.95-100
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• 1992

The radioisotopic measurement of glomerular filtration rate (GFR) has required analysis of serial blood or urine samples over several hours, and does not allow measurement of separate renal function unless separate catherterization of individual ureters is done. Gates described isotopic method for the measurement of global and unilateral GFR based on the determination by scintillation camera of the fraction of the injected dose of $^{99m}Tc-diethylenetriaminepentaacetic$ acid (DTPA) present in the kidneys 2-3 minutes after its administration. We calculated GFR according to Gates' method in 58 adult patients with various levels of global renal function using $^{99m}Tc$ DTPA and validated this technique by correlation with 24 hour creatinine clearance. A good correlation was observed between 24 hour creatinine clearance and GFR calculated by Gates' formula, with an r value of 0.91 (p<0.01). We concluded that determination of GFR according to the Gates' formula allows good and reproducible prediction of GFR with great rapidity and simplicity rendering this technique suitable for clinical practice.

• Preventive Nutrition and Food Science
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• v.7 no.3
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• pp.293-298
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• 2002

Carnitine is considered a conditionally essential nutrient because dietary sources may become important under conditions which either reduce biosynthesis or increase urinary excretion of carnitine. Therefore, it is important to have a database for dietary analysis for carnitine content. Because there is limited data available for the carnitine content of Korean foods, this study was undertaken to analyze the total carnitine (TCNE) content of 146 commonly consumed Korean foods. TCNE concentrations were assayed using a modified radioisotopic method. Beef and pork contained 91.09 and 17.21 mg TCNE / 100 g weight, respectively. Fish and shellfish ranged from 0.28 to 24.87 mg TCNE / 100g weight. TCNE concentration in milk was 1.77 mg / 100 mL and cheese was 0.49 mg / 100 g weight. Cereals and pulses contained between 0 and 1.43 mg TCNE / 100 g weight. The TCNE concentration of most fruits and vegetables was between 0 and 0.7 mg 1100 g weight. However, mushrooms contained between 2.77 and 7.02 mg of TCNE / 100 g weight. Soy sauce, soybean paste and fermented red pepper soybean paste contained 1.05, 0.28 and 0.5 mg TCNE / 100 g weight, respectively. These results demonstrate that TCNE concentrations are high in meat, fish, shellfish and milk, but low or non-existent fruits and vegetables. However, mushrooms are a substantial source of vegetable derived TCNE. These data will be useful in establishing a database for determining the TCNE content of Korean diets.

• Journal of Radiation Protection and Research
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• v.40 no.2
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• pp.101-109
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• 2015

Alpha spectrometry is typically used for the assessment of uranium particle concentrations and its accuracy can be directly related to the accuracy in which the radiochemical pre-treatment is conducted. Ashing and alkali fusion methods are typically used but the ashing method requires longer analysis time and the alkali fusion method is extremely costly. Therefore, a new pre-treatment method using ultrasonic cleaning was developed and its experimental result was compared against the two conventional methods in terms of pre-treatment time, convenience, cost, and recovery rate of a target material. The results that were obtained by the conventional methods(ashing and alkali fusion) and the new method were compared. Consequently, even though the shorter pre-treatment time was required, the new technique showed almost same recovery rate comparing with two conventional methods. The new method was also featured by its relatively lower cost and a simpler process than two conventional methods.