• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.1
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• pp.50-67
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• 2015

The Cognitive Radio (CR) paradigm in tactical ad hoc networks is an important element of future military communications for network-centric warfare. This paper presents a novel Cognitive Link State Routing protocol for CR-based tactical ad hoc networks. The proposed scheme provides prompt and reliable routes for Primary User (PU) activity through procedures that incorporate two main functions: PU-aware power adaptation and channel switching. For the PU-aware power adaptation, closer multipoint relay nodes are selected to prevent network partition and ensure successful PU communication. The PU-aware channel switching is proactively conducted using control messages to switch to a new available channel based on a common channel list. Our simulation study based on the ns-3 simulator demonstrates that the proposed routing scheme delivers significantly improved performance in terms of average end-to-end delay, jitter, and packet delivery ratio.

• Proceedings of the Korea Information Processing Society Conference
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• 2009.11a
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• pp.607-608
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• 2009

최근 7.7 DDoS 대란과 폭발적인 SPAM 발송과 같은 다양한 봇넷의 악성행위는 정보 시스템에 막대한 악영향을 미친다. 특히, 봇넷의 구조적 특징인 좀비PC의 제어는 네트워크 환경에서는 다양한 악성 행위를 유발한다. 때문에, 봇넷 탐지와 관련한 다양한 연구가 시도되었지만, 탐지의 한계점을 지니고 있다. 즉, 기존의 봇넷 탐지 방법은 임의의 임계값을 설정하고, 그 값을 벗어나는 시점에서 경고를 보내어 탐지하게 된다. 하지만, 전문가에 의한 임계값 설정은 자칫 오탐율과 미탐율을 야기할 수 있다. 따라서, 본 논문에서는 봇넷 탐지를 보다 능동적으로 하기 위하여 특정 타임 윈도우 구간동안의 봇넷이 유발하는 네트워크 트래픽을 분석하고 마르코프 체인을 응용한 학습을 하여 능동적으로 적용 가능한 임계값을 측정 방법론에 대하여 고찰하고자 한다.

• BMB Reports
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• v.28 no.5
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• pp.437-442
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• 1995

The potency of yeast-derived methionyl-free human growth hormone (rhGH), which was obtained by removal of the N-terminal Met from methionyl-hGH, was estimated by in vitro and in vivo assays. In radio-receptor assay where the binding affinity of growth hormone to the receptor was estimated, the recombinant hGH showed 2.9 international units (IU) per mg of specific activity. In contrast, pitUitary-derived human growth hormone had a slightly lower receptor binding activity (2.5 IU/mg) compared with recombinant growth hormone. For the in vivo assay, efficacy of rhGH was tested by use of hypophysectomized rats, in which pituitary organs were surgically removed, resulting in the termination of growth hormone secretion. The weight-increase in rats by the injection of rhGH was almost identical to the result obtained by the injection of the same amount of pituitary-derived (international standard) hGH. A comparision of the secondary structures of rhGH and rMet-hGH by circular dichroism spectrophotometer demonstrated that the removal of the methionyl residue from rMet-hGH did not exert any effect on the structure of the growth hormone. In conclusion, methionyl-free human growth hormone produced from yeast was highly potent in biological activity and maintained a legitimate three dimensional structure.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.9
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• pp.4367-4375
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• 2016

The objective of the present study was to evaluate the anticancer and radio-sensitizing efficacy of a Withania somnifera extract/Gadolinium III oxide nanocomposite (WSGNC) in mice. WSGNC was injected to solid Ehrlich carcinoma-bearing mice via i.p. (227 mg/kg body weight) 3 times/week during 3 weeks. Irradiation was performed by whole body fractionated exposure to 6Gy, applied in 3 doses of 2 Gy/week over 3 weeks. Biochemical analyses as well as DNA fragmentation were performed. Treatment of solid Ehrlich carcinoma bearing mice with WSGNC combined with ${\gamma}$-radiation led to a significant decrease in the tumor size and weight associated with a significant decrease in mitochondrial enzyme activities, GSH content and SOD activity as well as a significant increase in caspase-3 activity, MDA concentration and DNA fragmentation in cancer tissues. Combined treatment of WSGNC and low dose of ${\gamma}$-radiation showed great amelioration in lipid peroxidation and antioxidant status (GSH content and SOD activity) in liver tissues in animals bearing tumors. It is concluded that WSGNC can be considered as a radio-sensitizer and anticancer modulator, suggesting a possible role in reducing the radiation exposure dose during radiotherapy.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.2
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• pp.36.3-37
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• 2015

4C39.25 (0923+392) is a distant radio loud AGN placed at redshift 0.695. The motivation of our work is peculiar properties 4C39.25. Firstly, it has a conspicuous distinction of jet direction between kilo-parsec scale observation made by VLA (Kollgaard et al. 1990) and the parsec scale observation by VLBA (Kellermann et al. 1998). This might indicate episodic-jet activity which recently turned on. This object currently shows two stationary compact parsec-scale components which are bright jet component on east and less luminous core on west. Also, it is known that there have been superluminal jet components which are flowing from the core toward east, and then merging with the bright jet component (Marscher et al. 1991, Alberdi et al. 2000, Lister et al. 2013). Although 4C39.25 seems to be a blazar-like source having broad emission lines (SDSS) and superluminal motion, its property that jet component is brighter than the core is different from ordinary blazars. Furthermore, it has young radio galaxy-like properties such as non-variation in total flux (Alberdi et al. 1997, 2000, MOJAVE database) and high frequency peak at spectral energy distribution (Orienti et al 2007). Such complex properties led us to make recent observations to reveal precise properties and new changes of the source. We used Korean VLBI Network (KVN) and VLBI Exploration of Radio Astronomy (VERA) Array (KaVA) which provide high-frequency (23GHz and 43GHz) and high spatial resolution (1.2mas and 0.6mas). Therefore, this system is suitable for morphological and physical research on parsec scale structure. We present results for several epochs observed during 2013 to 2014, mainly focusing on morphological changes of 4C39.25 using KaVA images.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37C no.11
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• pp.1112-1128
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• 2012

In cognitive radio networks, secondary users are allowed to utilize the channels currently not occupied by primary users opportunistically. Secondary users can communicate with each other using the commonly available channels (common channels) which may change dynamically based on the activity of the primary users. Even though many studies have dealt with cognitive radio behaviors, the detailed procedures for common channel configuration have not been paid much attention. In this paper, the fast and reliable dynamic common channel setup and reconstruction method for the point-to-point communications in military cognitive radio networks is proposed. The detailed time parameters are considered for common channel setup and reconstruction, such as the packet exchange time, channel request waiting time, and rendezvous time. Through numerical analyses, the delay and throughput performance of the proposed method is derived and evaluated.

• Journal of Life Science
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• v.17 no.5 s.85
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• pp.664-670
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• 2007

The propolis is natural product produced by honeybees and is known to have many biologically useful properties such as anti-microbial, anti-oxidative and anti-tumorigenic activity. However, its radio-protective property has not been well studied. To investigate radio-protective effect of propolis on mouse testis, mice were supplemented with propolis after 5 Gy irradiation. The histological changes of testis were detected by TEM. The results indicate that propolis may protect tissue deformation which is induced by 5 Gy of ionizing radiation. Furthermore, to elucidate the potential molecular mechanisms involved in radio-protective property of propolis, we performed microarray experiments using oligo DNA microarray. We found 65 up-regulated genes and 224 down-regulated genes, whose expression levels were affected more than 2-fold by propolis treatment in mice irradiated at 5 Gy. We confirmed microarray data with reverse transcription-PCR using gene specific primers. The results of RT-PCR are highly correlated with those of microarray. These results may help understanding molecular mechanisms of radioprotective effects by propolis in mouse model.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.10
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• pp.4661-4680
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• 2016

Cognitive radio (CR) technology is an effective solution to the spectrum scarcity issue. Collaborative spectrum sensing is known as a promising technique to improve the performance of spectrum sensing in cognitive radio networks (CRNs). However, collaborative spectrum sensing is vulnerable to spectrum data falsification (SSDF) attack, where malicious users (MUs) may send false sensing data to mislead other secondary users (SUs) to make an incorrect decision about primary user (PUs) activity, which is one of the key adversaries to the performance of CRNs. In this paper, we propose a coalition based malicious users detection (CMD) algorithm to detect the malicious user in CRNs. The proposed CMD algorithm can efficiently detect MUs base on the Geary'C theory and be modeled as a coalition formation game. Specifically, SSDF attack is one of the key issues to affect the resource allocation process. Focusing on the security issues, in this paper, we analyze the power allocation problem with MUs, and propose MUs detection based power allocation (MPA) algorithm. The MPA algorithm is divided into two steps: the MUs detection step and the optimal power allocation step. Firstly, in the MUs detection step, by the CMD algorithm we can obtain the MUs detection probability and the energy consumption of MUs detection. Secondly, in the optimal power allocation step, we use the Lagrange dual decomposition method to obtain the optimal transmission power of each SU and achieve the maximum utility of the whole CRN. Numerical simulation results show that the proposed CMD and MPA scheme can achieve a considerable performance improvement in MUs detection and power allocation.

• Archives of Pharmacal Research
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• v.14 no.4
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• pp.290-294
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• 1991

For the determination of peripheral COMT activity, we synthesized $[2-^{14}C]-3',4'-dihydroxyacetophenone([^{14}C]-DHAP)$, a model substrate closely related to catecholamines, which cannot be attacked by monoamine oxidase. After i.v.-injection of $[^{14}C]-DHAP$ in living animals, only 3',4'-dihydroxy-acetophenone (3',4'-DHAP) and 3'-methoxy-4'-hydroxyacetophenone (3'-MHAP) were detected in blood by thin layer radio chromatography. It could be speculated that 3',4'-DHAP was primarily O-methylated by COMT, followed by subsequent conjugations. The concentration of 3',4'-DHAP, a substrate for COMT, in blood at 5 min after injection of $[^{14}C]-DHAP$, were similar in all animals. The rate of 3'-MHAP formation can be therefore used as an indicator for peripheral COMT activity. The velocity of methylation in 15 min after i.v.-administration of $[^{14}C]-DHAP$ was $0.28\;{\mu}g/ml{\cdot}min$. From these results, 3',4'-DHAP was shown to be used as an appropriate substrate to determine the COMT activity in vivo.

• Nuclear Engineering and Technology
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• v.12 no.2
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• pp.106-110
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• 1980

The radio-equilibrium conditions of uranium and thorium in the Okcheon black shales and monazites have been studied. As the results. a radiometric method based on the measurements of gamma ray activity has been suggested for the simple analysis of many samples in the process of the prospecting and the grading of uranium and thorium minerals.