• Title/Summary/Keyword: Radio Activation

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Verification of MCNP/ORIGEN-2 Model and Preliminary Radiation Source Term Evaluation of Wolsung Unit 1 (월성 1호기 MCNP/ORIGEN-2 모델 검증 및 예비 선원항 계산)

  • Noh, Kyoungho;Hah, Chang Joo
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.13 no.1
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    • pp.21-34
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    • 2015
  • Source term analysis should be carried out to prepare the decommissioning of the nuclear power plant. In the planning phase of decommissioning, the classification of decommissioning wastes and the cost evaluation are performed based on the results of source term analysis. In this study, the verification of MCNP/ORIGEN-2 model is carried out for preliminary source term calculation for Wolsung Unit 1. The inventories of actinide nuclides and fission products in fuel bundles with different burn-up were obtained by the depletion calculation of MCNPX code modelling the single channel. Two factors affecting the accuracy of source terms were investigated. First, the neutron spectrum effect on neutron induced activation calculation was reflected in one-group microscopic cross-sections of relevant radio-isotopes using the results of MCNP simulation, and the activation source terms calculated by ORIGEN-2 using the neutron spectrum corrected library were compared with the results of the original ORIGEN-2 library (CANDUNAU.LIB) in ORIGEN-2 code package. Second, operation history effect on activation calculation was also investigated. The source terms on both pressure tubes and calandria tubes replaced in 2010 and calandria tank were evaluated using MCNP/ORIGEN-2 with the neutron spectrum corrected library if the decommissioning wastes can be classified as a low level waste.

Study on the creative development of China Cartoon & Animation - Focusing on changes in a production environment with supporting the policy of the State Administration of Press, Publication, Radio, Film and Television of China - (중국 만화 애니메이션 창작과 발전 방향에 관한 연구 -국가광전총국(國家廣電總局) 지원정책에 따른 제작환경 변화를 중심으로-)

  • Xie, Shu-Fu;Kim, Jong-Du
    • Cartoon and Animation Studies
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    • s.35
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    • pp.209-226
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    • 2014
  • Chinese cartoon industry lately was able to see a rapid development which changed cartoon creative personnel associated with increased production technology development, new technologies, government support policy and a variety of environments. It was likely to have high expectations for changes in the policy environment of the country supported the comic creators and authors to develop its own comic industry. The State Administration of Press, Publication, Radio, Film and Television of China promoted the production for the development of Chinese animation with "domestic little video about the development of the animation industry's opinion", and "documents Documents". Animation industrial base and animation education was established in institutions such as the organization one after another. In the meantime, the spread of Japanese comics picture on the creative activation admitted but their comic creation and activation was slump. It would produce that the creation of its traditional culture based activation strategy to built comics. Since 2004, It was well represented for the creators of the cartoon creation of the tradition and uniqueness of Chinese history. In the prior to 2004, comics and strategies was to be differentiated. Today, China is an important source of comic marked the fact that the tradition was recognized and it was further developed with combining creativity of the past and the present production system. Comic creators comic story of traditional culture were excavated in order to have a sense of awareness and modern. The difference between China Cartoon and comics in other Asian countries is true that cartoon story came out naturally in a traditional culture. In this study, It would lead in the future to allow directional presented for the digital cartoon making development policy awareness through the comic creation and production of new media content industry enabled to China. Now, in the new media industry for the development of China's neighboring countries coped with climate change for the active exchange of information. It poured out ceaseless technical development and a range of policies to support business expansion. New China Cartoon was leaped to re-fit the industry.

p53 Nuclear Accumulation as a Possible Biomarker for Biological Radio-dosimetry in Oral Mucosal Epithelial Cells

  • Kim, Youn-Young;Kim, Jong-il;Kim, Jin;Yook, Jong-In;Kim, The-Hwan;Son, Young-Sook
    • BMB Reports
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    • v.34 no.2
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    • pp.123-129
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    • 2001
  • Cellular response to ionizing radiation is affected by cell types, radiation doses, and post-irradiation time. Based on the trypan blue dye exclusion assay in normal oral mucosal cells (OM cells), a 48 h post-irradiation was sufffcient and an adequate time point for the evaluation of radiation sensitivity Its $LD_{50}$ was approximately 1.83 Gy To investigate possible biomarkers useful for the biological radiodosimetry of normal epithelial cells (p53, c-fos, cyclin D1, cdc-2, pRb) EGF receptor phosphorylation and Erk activation were evaluated at different radiation doses and different post-irradiation times. From 0.5 Gy, p53 was accumulated in the nucleus of basal cells of the OM raft culture at 4 h post-irradiation and sustained up to 24 h post-irradiation, which suggests that radiation-induced apoptosis or damage repair was not yet completed. The number of p53 positive cells and biosynthesis of p53 were correlated with radiation doses. Both cyclin D1 and c-fos were only transiently induced within 1 h post-irradiation. Cyclin D1 was induced at all radiation doses. However, cfos induction was highest at 0.1 Gy, approximately 7.3 fold more induction than the control, whose induction was reduced in a reverse correlation with radiation dose. The phosphorylation pattern of cdc-2 and pRb were unaffected by radiation. In contrast to A431 tails overexpressing the EGF receptor approximately 8.5 fold higher than normal epithelial, the OM cells reduced the basal level of the EGF receptor phosphorylation in a radiation dose dependent fashion. In conclusion, among radiation-induced biomolecules, the p53 nuclear accumulation may be considered for the future development of a useful marker far biological radiodosimetry in normal epithelial tissue since it was sustained for a longer period and showed a dose response relationship. Specific c-fos induction at a low dose may also be an important finding in this study It needs to be studied further for the elucidation of its possible connection with the low dose radio-adaptive response.

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Iodine Isotope Exchanges Between o-lodohippuric Acid and Radioiodide (오르토 요오도히퓨린산과 방사성요오드 이온간의 요오드 등위원소 교환반응)

  • Jae-Rok Kim;Ok-Doo Awh;Hyeon-Sook Koo;Kyung-Bae Park
    • Nuclear Engineering and Technology
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    • v.13 no.3
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    • pp.145-152
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    • 1981
  • Even though a lately reported method of high temperature exchange labelling of o-iodo-hippuric acid (Hippuran) in the absence of oxidizing agent was considered to be an attractive one, the exchange mechanism was somewhat unclear. In this study iodine isotope exchanges between o-iodohippuric acid (OIH) and radioiodide ($^{125}$ $I^{ }$) or between OIH and molecular radioiodine ($^{125}$ $I_2$) were carried out at two different temperatures. Rate constants and activation parameters were measured by applying a radio-paper chromatography technique. Since o-iodobenzoic acid is known as a by-product in the exchange labelling of OIH, data were also obtained for the OIB-iodide systems for comparison. The rate constant was increased in the order of OIB...$^{125}$ $I^{[-10]}$ >OIB...$^{125}$ $I_2$>OIH..$^{125}$ $I^{[-10]}$ >OIH...$^{125}$ $I_2$ and the activation parameters for OIH were generally larger than those for OIB :$\Delta$H$\neq$$_{OIH}$>$\Delta$H$\neq$$_{OIB}$, $\Delta$S$\neq$$_{OIH}$>$\Delta$S$\neq$$_{OIB}$. These results suggest that the mechanism of the high temperature exchange is predominantly nucleophilic even though some electrophilic character can also be involved depending upon reaction conditions. Such a fact may well be caused by a feasible formation of hydrogen bonding type transition state due probably to the ortho substituent effect of-CONHC $H_2$COOH. Thus, the high temperature exchange method is estimated to be quite effective for labelling Hippuran especially at a small research center where reducing agent-free $^{131}$ I is unavailable.ailable..

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Design and Implementation of Chatting Service and Common Use Phrase Function WIPI Platform (WIPI 환경에서 문자 대화 서비스 및 상용어구 기능의 설계 및 구현)

  • Lim Chang-Mook;Jung Sung-Hoon;Kim Chang-Soo;Park Si-Hyoung;Lim Jae-Hong
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2004.11a
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    • pp.9-13
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    • 2004
  • Mobile Internet has different platforms cause interrupt activation of mobile internet because contents providers have each different development environment. To use of WIPI(Wireless Internet Platform for Interoperability) developer by KWISF(Korea Wireless Internet Standard Forum) founded to solve this problem guarantee independence of hardware and interpretation of mobile application. In this paper, Examine WIPI's characteristic and main standard that is standard platform that can reduce expense that happen in current different platform in treatise. And. common use phrase function that consider convenience of chatting service between portable phone that is that is used recently design and embody. Wish to argue about elevation of the character input speed of portable phone and effect that happen thereby through this.

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Chlorination of Phenyl Derivatives : Chlorination of ethyl -${\alpha},{\beta}-dichloro-{\beta}$-phenyl propionate under gamma ray irradiation (芳香族 誘導體의 염素化反應 Ethyl-${\alpha},{\beta}-dichloro-{\beta}$-phenyl propionate의 gamma 線 鹽素化反應)

  • Kim, You-Sun;Kim, Ki-Soo
    • Journal of the Korean Chemical Society
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    • v.12 no.2
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    • pp.55-60
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    • 1968
  • Chlorination of aromatic derivatives under UV light and ${\gamma}$-ray irradiation was studied. Ethyl ${\alpha} ,{\beta} -dichloro-{\beta}$-phenyl propionate gave the p-chlorophenyl derivatives when chlorination was done under UV light. The same type of the product was obtained in the reaction where the mole ratio of the ester and chlorine was 1 to 2 and the chlorination was done under ${\gamma}$-ray irradiation. When the mole ratio of the ester and chlorine was 1 to 8, the chlorination reaction under ${\gamma}$-ray irradiation gave a poly-chlorinated derivatives which was identified as a side chain chlorinated p-chlorophenyl derivatives. Ethyl ${\alpha} ,{\beta} -dichloro-{\beta}$-(p-chlorophenyl) propionate gave the same type of the side chain chlorinated p-chloro derivatives by the chlorination under ${\gamma}$-ray irradiation, whereas ethyl ${\alpha} ,{\beta} -dichloro-{\beta}$-(o-chlorophenyl) derivatives gave o,p-dichlorophenyl derivatives. The identifications of the products were based on a radio thin layer chromatography and activation analysis of chlorine contents of product. The chlorination reaction was discussed in regards to the effect of phenyl substituents to the formation of reaction product and the procedures were described.

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Sirt1 Promotes DNA Damage Repair and Cellular Survival

  • Song, Seung-Hyun;Lee, Mi-Ok;Lee, Ji-Seon;Oh, Je-Sok;Cho, Sung-Uk;Cha, Hyuk-Jin
    • Biomolecules & Therapeutics
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    • v.19 no.3
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    • pp.282-287
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    • 2011
  • Sirt1, a nicotinamide adenine dinucleotide ($NAD^+$)-dependent histone deacetylase, is known to deacetylate a number of proteins that are involved in various cellular pathways such as the stress response, apoptosis and cell growth. Modulation of the stress response by Sirtuin 1 (Sirt1) is achieved by the deacetylation of key proteins in a cellular pathway, and leads to a delay in the onset of cancer or aging. In particular, Sirt1 is known to play an important role in maintaining genomic stability, which may be strongly associated with a protective effect during tumorigenesis and during the onset of aging. In these studies, Sirt1 was generated in stably expressing cells and during the stimulation of DNA damage to examine whether it promotes survival. Sirt1 expressing cells facilitated the repair of DNA damage induced by either ionizing radiation (IR) or bleomycin (BLM) treatment. Fastened damaged DNA repair in Sirt1 expressing cells corresponded to prompt activation of Chk2 and ${\gamma}$-H2AX foci formation and promoted survival. Inhibition of Sirt1 enzymatic activity by a chemical inhibitor, nicotinamide (NIC), delayed DNA damage repair, indicating that promoted DNA damage repair by Sirt1 functions to induce survival when DNA damage occurs.

Development of ATP Train Separation Control Simulator for Radio-based Train Control System (무선통신기반 열차제어시스템 ATP 열차간격제어알고리즘 시뮬레이터 개발)

  • Yoon, Yong-Ki;Oh, She-Chan;Choi, June-Young;Park, Jae-Young;Yang, Hai-Won
    • Journal of the Korean Society for Railway
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    • v.15 no.1
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    • pp.29-36
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    • 2012
  • This paper includes ATP(Automatic Train Protection) simulator development and ATP algorithm verification to allocate wayside and train-borne and verify ATP functions of communications based train control system. The train control system has some characteristics such as simple structure and high safety when wireless communication technology is applied to the train control system. Especially, vital functions can be performed with in wayside and train-borne ATP. However, different system can be realized because I/F contents vary in accordance with vital functional allocation of ATP. Drawing characteristics in accordance with wayside and train-borne functional allocation and drawing I/F details affected by such characteristics are needed accordingly. This paper includes ATP simulator development creating train location information by direct activation of an electric motor, verifies train safety distance control algorithm of ATP by functional allocation such as train movement authority and train speed limit to ATP, and draws any supplementation needed. Appropriate simulated environment for verify ATP algorithm and main factors that affect to the ATP function were confirmed.

Toxicity of Natural Uranium in Rats (천연우라늄의 독성에 관한 실험 연구)

  • Ryu, Yong-Wun;Lee, Jhin-Oh;Yun, Taik-Koo
    • Journal of Radiation Protection and Research
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    • v.11 no.1
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    • pp.44-50
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    • 1986
  • Tissue distribution and blood chemistry of uranium in serum levels of BUN, Creatinine, SGPT and SGOT were determined in rats after the administration of uranylnitrate. Determination of uranium in organ was done by radio activation analysis. Radioactivity of $^{239}Np$ in lung was higher than in other tissues (e.g. liver, kidneys, spleen, tibia, testes, stomach and brain). Correlations between BUN and Creatinine were positively increased after the administration of 25 mg/kg uranylnitrate. The SGPT and SGOT activities showed weak correlation with the control group. However, activities of SGPT and SGOT after the administration of lmg/kg uranylnitrate showed high peak at 90 min interval. Uranium uptake by liver and kidneys increased at early period and decreased immediately to the control level. Lung who confirmed to be the critical organ on toxic effect by uranylnitrate.

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Design and Implementation of J2ME-based Wired/Wireless Interworking Mobile Wallet (J2ME 기반 유.무선 연동의 모바일 전자지갑 설계 및 구현)

  • Park, Nam-Je;Song, You-Jin
    • The KIPS Transactions:PartC
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    • v.9C no.5
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    • pp.687-698
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    • 2002
  • Together with the activation of wireless Internet, the interest for various integrated methods of the existing wired and wireless e-commerces is on the rise. For the integrated wired and wireless e-commerce, firstly, the optimized security and authentication under the radio communication environment should be decided. And also the user-friendly usage is important. In this paper, we designed and implemented wired and wireless interworking Mobile Wallet on terminal that can be used through both wired and wireless methods by developing electronic wallet module for electronic payment using MIDP (Mobile Information Device Profile) based on J2ME (Java 2 Micro Edition). The characteristics of mobile wallet implemented in this paper provide the stability through encoding/decoding payment information and on-line usage on wired/wireless environments through downloading electronic wallet. In addition, we also present safe and convenient payment method for e-commerce based on wired/wireless Internet.