Sirt1 Promotes DNA Damage Repair and Cellular Survival |
Song, Seung-Hyun
(Department of Biomedical Science, CHA University)
Lee, Mi-Ok (Department of Biomedical Science, CHA University) Lee, Ji-Seon (Department of Life Sciences, College of Natural Sciences, Sogang University) Oh, Je-Sok (Department of Biotechnology and Environmental Engineering, Catholic University) Cho, Sung-Uk (Department of Biomedical Science, CHA University) Cha, Hyuk-Jin (Department of Life Sciences, College of Natural Sciences, Sogang University) |
1 | Sedding, D. G. (2008). FoxO transcription factors in oxidative stress response and ageing--a new fork on the way to longevity? Biol. Chem. 389, 279-283. DOI |
2 | Stunkel, W., Peh, B. K., Tan, Y. C., Nayagam, V. M., Wang, X., Salto- Tellez, M., Ni, B., Entzeroth, M. and Wood, J. (2007). Function of the SIRT1 protein deacetylase in cancer. Biotechnol. J. 2, 1360-1368. DOI |
3 | Vaziri, H., Dessain, S. K., Ng Eaton, E., Imai, S. I., Frye, R. A., Pandita, T. K., Guarente, L. and Weinberg, R. A. (2001). hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107, 149-159. DOI |
4 | Wang, R., Sengupta, K., Li, C., Kim, H., Cao, L., Xiao, C., Kim, S., Xu, X., Zheng, Y., Chilton, B., Jia, R., Zheng, Z., Appella, E., Wang, X., Ried, T. and Deng, C. (2008). Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell 14, 312-323. DOI |
5 | Yeung, F., Hoberg, J. E., Ramsey, C. S., Keller, M. D., Jones, D. R., Frye, R. A. and Mayo, M. W. (2004). Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23, 2369-2380. DOI |
6 | Yuan, Z., Zhang, X., Sengupta, N., Lane, W. and Seto, E. (2007). SIRT1 regulates the function of the Nijmegen breakage syndrome protein. Mol. Cell 27, 149-162. DOI |
7 | Huffman, D. M., Grizzle, W. E., Bamman, M. M., Kim, J. S., Eltoum, I. A., Elgavish, A. and Nagy, T. R. (2007). SIRT1 is signifi cantly elevated in mouse and human prostate cancer. Cancer Res. 67, 6612-6618. DOI |
8 | Kim, E. J., Kho, J. H., Kang, M. R. and Um, S. J. (2007). Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. Mol. Cell 28, 277-290. DOI |
9 | Jeong, J., Juhn, K., Lee, H., Kim, S., Min, B., Lee, K., Cho, M., Park, G. and Lee, K. (2007). SIRT1 promotes DNA repair activity and deacetylation of Ku70. Exp. Mol. Med. 39, 8-13. DOI ScienceOn |
10 | Keogh, M., Kim, J., Downey, M., Fillingham, J., Chowdhury, D., Harrison, J., Onishi, M., Datta, N., Galicia, S., Emili, A., Lieberman, J., Shen, X., Buratowski, S., Haber, J., Durocher, D., Greenblatt, J. and Krogan, N. (2006). A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature 439, 497-501. DOI |
11 | Lee, J. S., Lee, M. O., Moon, B. H., Shim, S. H., Fornace, A. J. Jr. and Cha, H. J. (2009). Senescent growth arrest in mesenchymal stem cells is bypassed by Wip1-mediated downregulation of intrinsic stress signaling pathways. Stem Cells 27, 1963-1975. DOI |
12 | Lee, J. S., Park, K. Y., Min, H. G., Lee, S. J., Kim, J. J., Choi, J. S., Kim, W. S. and Cha, H. J. (2010). Negative regulation of stress-induced matrix metalloproteinase-9 by Sirt1 in skin tissue. Exp. Dermatol. 19, 1060-1066. DOI |
13 | Michan, S. and Sinclair, D. (2007). Sirtuins in mammals: insights into their biological function. Biochem. J. 404, 1-13. DOI ScienceOn |
14 | Mochan, T. A., Venere, M., DiTullio, R. A. Jr. and Halazonetis, T. D. (2003). 53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage. Cancer Res. 63, 8586-8591. |
15 | Motta, M. C., Divecha, N., Lemieux, M., Kamel, C., Chen, D., Gu, W., Bultsma, Y., McBurney, M. and Guarente, L. (2004). Mammalian SIRT1 represses forkhead transcription factors. Cell 116, 551-563. DOI |
16 | Chang, C. J., Hsu, C. C., Yung, M. C., Chen, K. Y., Tzao, C., Wu, W. F., Chou, H. Y., Lee, Y. Y., Lu, K. H., Chiou, S. H. and Ma, H. I. (2009). Enhanced radiosensitivity and radiation-induced apoptosis in glioma CD133-positive cells by knockdown of SirT1 expression. Biochem. Biophys. Res. Commun. 380, 236-242. DOI |
17 | Brooks, C. L. and Gu, W. (2009). How does SIRT1 affect metabolism, senescence and cancer? Nat. Rev. Cancer 9, 123-128. DOI |
18 | Burma, S., Chen, B. P., Murphy, M., Kurimasa, A. and Chen, D. J. (2001). ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem. 276, 42462-42467. DOI |
19 | Cha, H., Lowe, J. M., Li, H., Lee, J. S., Belova, G. I., Bulavin, D. V. and Fornace, A. J. Jr. (2010). Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response. Cancer Res. 70, 4112-4122. DOI |
20 | Cohen, H. Y., Miller, C., Bitterman, K. J., Wall, N. R., Hekking, B., Kessler, B., Howitz, K. T., Gorospe, M., de Cabo, R. and Sinclair, D. A. (2004). Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305, 390-392. DOI ScienceOn |
21 | Dean, M., Fojo, T. and Bates, S. (2005). Tumour stem cells and drug resistance. Nat. Rev. Cancer 5, 275-284. DOI |
22 | Deng, C. (2009). SIRT1, is it a tumor promoter or tumor suppressor? Int. J. Biol. Sci. 5, 147-152. |
23 | Franken, N. A., Rodermond, H. M., Stap, J., Haveman, J. and van Bree, C. (2006). Clonogenic assay of cells in vitro. Nat. Protoc. 1, 2315-2319. DOI |
24 | Guarente, L. and Picard, F. (2005). Calorie restriction--the SIR2 connection. Cell 120, 473-482. DOI |
25 | Bradbury, C. A., Khanim, F. L., Hayden, R., Bunce, C. M., White, D. A., Drayson, M. T., Craddock, C. and Turner, B. M. (2005). Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors. Leukemia 19, 1751-1759. DOI |
26 | Hong, E. H., Lee, S. J., Kim, J. S., Lee, K. H., Um, H. D., Kim, J. H., Kim, S. J., Kim, J. I. and Hwang, S. G. (2010). Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase. J. Biol. Chem. 285, 1283-1295. DOI ScienceOn |
27 | Bao, S., Wu, Q., McLendon, R. E., Hao, Y., Shi, Q., Hjelmeland, A. B., Dewhirst, M. W., Bigner, D. D. and Rich, J. N. (2006). Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444, 756-760. DOI |
28 | Bitterman, K. J., Anderson, R. M., Cohen, H. Y., Latorre-Esteves, M. and Sinclair, D. A. (2002). Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J. Biol. Chem. 277, 45099-45107. DOI ScienceOn |