• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.2027-2030
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• 2016

Objective: To investigate the effect of peripheral blood CD4 + CD25 + regulatory T cell on postoperative immunotherapy in patients with renal carcinoma. Methods: 38 patients with renal cell carcinoma were recruited, and 20 patients from the operation group purely underwent the radical nephrectomy therapy, 18 patients from the combined group successively underwent the radical nephrectomy therapy and IFN-${\alpha}$ adjuvant immunotherapy. Additionally, 12 healthy subjects were recruited in the same period of time and regarded as the control group. Flow cytometry was used to detect CD4 +, CD8 +, CD4 + CD25+ T lymphocyte subset content and the ratio of all parts in the pre-operative period, in the first post-operative week and in the third post-operative month, compare and analyze its variation trend. Results: The CD4+CD25+ T lymphocyte subset content of individual renal carcinoma patients was significantly higher than that of the control group, also increases with the progression in the tumor stage (P<0.05). The post-operative CD4 + CD25+T lymphocytes of individual operation group and combined group patients showed different degrees of increment, but the increment of the combined group was significantly lower than that of the operation group (P<0.05). For the combined group patients with less pre-operative CD4 + CD25+T lymphocytes, their levels would increase after the immunotherapy, while the pre-operative patients with more CD4 + CD25+ T lymphocytes were the opposite situation. Conclusion: The detection of peripheral blood CD4+CD25+ regulatory T lymphocyte subset can reflect the anti-tumor immune status of renal cell carcinoma patient body. It can contribute to predict the prognosis of immunotherapy and provide reference for the choice of renal carcinoma post-operative adjuvant immunotherapy.

• Korean Journal of Bronchoesophagology
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• v.3 no.2
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• pp.287-292
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• 1997

We report 22 cases of well -differentiated thyroid carcinoma infiltrating the upper airway tract. This retrospective study was undertaken to evaluate the prognosis md to determine optimal therapy for thyroid carcinoma adhering to or invading the trachea or larynx from 1984.3 to 1996.12. The treatment was individualized depending on the extent of the cancer. There were 12 cases dissected free by an laryngotracheal shaving, 7 cases removed by an tracheal resection with end to end anastomosis, 3 cases removed by an total laryngectomy. In all of these cases, we performed a total thyroidectomy with an accompanying neck dissection. There were no major complications during the operation. Over the 5-years observation period, 11 patients are alive without a sign of recurrence, 4 Patients are alive with recurrence, 7 died of thyroid carcinoma; 2 of 12 in an laryngotracheal shaving cases, 2 of 7 in an tracheal resection with end to end anastomosis case, 3 of 3 in an total laryngectomy case. The result showed an radical operation for thyroid carcinoma invading the laryngotrachea improves the survival rate, but limits improving the cure rate, and the invasion of the thrchea or larynx must be treated whenever possible by an total resection followed by radioiodine and external beam radiation.

• International Commerce and Information Review
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• v.11 no.3
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• pp.47-71
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• 2009

In order to implement e-trade infrastructure through the radical innovation of trade process, e-trade platform which is called 'uTradehub' has been developed for three years. After pilot operation of this platform in 2007, the formal service of e-trade such as logistics, customs and foreign exchanges had been provided in 2008. However, the usage of e-Trade platform is not the level of users' satisfaction because trade-related communities have not actively participated into e-trade platform and several functions with users requirements are necessary to develop additionally. In this regard, there are strong demands to suggest some strategies for application and usage proliferation of e-trade platform. Therefore, this paper would like to evaluate the current status of e-trade platform service and usage by the theoretical consideration of preceding researches and practical analysis of statistical data. Then, it will explore several service improvement ideas in terms of system supplementation and integration, electronic documents standardization, radical change of using fee, global connection, user oriented education and advertisement.

• 제어로봇시스템학회:학술대회논문집
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• 1993.10b
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• pp.36-41
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• 1993

The adiabatic slirn-type autoclave reactor for free radical polymerization of LDPE is represented by a two-compartment four-cell model, which is proven effective to predict the reactor behavior as well as the polymer properties. Since the temperature distribution along the reactor axis plays the central role for the properties of the polymer product, it is important in practice to regulate the temperature in each compartment. The present study aims for the application of the adaptive control algorithm not only in the period of start-up but also during the steady state operation. It is shown that the temperature control is significantly improved over the conventional PID-control and this also brings about a reduction of variations in the polymer properties. This study demonstrates the potential application of the adaptive controller for the control of the polymerization reactor operated under the adiabatic condition.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.1
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• pp.41-51
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• 2019

This study examined the relationship between dynamic capabilities and innovation performance and the mediating effect of exploration/exploitation operational capabilities as well as the moderating effect of exploration/exploitation IT capabilities. The results are as follows: seizing capability and reconfiguration capability had positive effects on incremental and radical innovation performance. Exploration and exploitation operational capability had positive effects on incremental innovation performance. Furthermore, exploration operation capability had a positive effect on radical innovation performance. 'Exploration operational capability-exploration IT capability' had moderating effects on 'exploration operational capability-exploitation IT capability', and 'exploitation operational capability-exploitation IT capability' on incremental innovation performance. Lastly, 'exploration operational capability-exploration IT capability' had a significant mediating effect on radical innovation performance. This study is the first empirical research that divides the effects of dynamic capabilities into direct and indirect effects, and the operational/IT capabilities into exploration and exploitation.. Dynamic and operational capabilities play a complementary role in adapting and evolving companies.

• Journal of Chest Surgery
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• v.14 no.3
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• pp.195-201
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• 1981

The results of reconstruction of the lower esophagus with jejunum in a total of 24 cases of primary carcinoma of the lower third esophagus and gastroesophageal carcinoma were presented, and clinical values of substitution for the esophagus with jejunum were also discussed. They were operated in the department of thoracic and cardiovascular surgery, Hanyang University Hospital during the period of 9 years from 1972 to 1981. Surgical managements to lower esophageal reconstruction with jejunum were carded out with not the same procedure in all cases studied, but with three different procedure mentioned below/ In 13 cases of lower third esophagectomy with or without partial `8astrectomy of a total of 24 cases, interposition of jejunum between the esophagus and the stomach were performed after the fashion to esophagojejunostomy with mobilized jejunal loops and 8astro-JeJunostomy with side to side anastomosis. In 7 cases of lower third esophagectomy and total gastrectomy, the continuity of the esophagus were performed the fashion to esophagojejunostomy with mobilized jejunum. In 4 cases of unresectable gastro-esophageal carcinoma, bypass operation of the lower esophagus and the stomach were performed after the fashion to esophagojejunostomy with side to and anastomosis. After the bypass operation, it was observed that oral feeding to the patients was excellent. Following these consecutive series of 20 cases of radical operation for lower esophageal carcinomas and 4 cases of bypass operation for unresectable gastroesophageal carcinomas, no complication such as postoperative leakage and stenosis from anastomotic site or Infection In operating area and operative death were observed.

• Journal of Chest Surgery
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• v.14 no.3
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• pp.202-209
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• 1981

The results of reconstruction of the lower esophagus with jejunum in a total of 24 cases of primary carcinoma of the lower third esophagus and gastroesophageal carcinoma were presented, and clinical values of substitution for the esophagus with jejunum were also discussed. They were operated in the department of thoracic and cardiovascular surgery, Hanyang University Hospital during the period of 9 years from 1972 to 1981. Surgical managements to lower esophageal reconstruction with jejunum were carded out with not the same procedure in all cases studied, but with three different procedure mentioned below/ In 13 cases of lower third esophagectomy with or without partial `8astrectomy of a total of 24 cases, interposition of jejunum between the esophagus and the stomach were performed after the fashion to esophagojejunostomy with mobilized jejunal loops and 8astro-JeJunostomy with side to side anastomosis. In 7 cases of lower third esophagectomy and total gastrectomy, the continuity of the esophagus were performed the fashion to esophagojejunostomy with mobilized jejunum. In 4 cases of unresectable gastro-esophageal carcinoma, bypass operation of the lower esophagus and the stomach were performed after the fashion to esophagojejunostomy with side to and anastomosis. After the bypass operation, it was observed that oral feeding to the patients was excellent. Following these consecutive series of 20 cases of radical operation for lower esophageal carcinomas and 4 cases of bypass operation for unresectable gastroesophageal carcinomas, no complication such as postoperative leakage and stenosis from anastomotic site or Infection In operating area and operative death were observed.

• The Journal of the Korean dental association
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• v.13 no.2
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• pp.175-179
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• 1975

I had treated a patient, 58 years old male, with squamous cell carcinoma in mandible. In the patient, radical operation was made by hemimandiblectomy, neck dissection and gnathoplasty with resin made mandible. The patient was radically treated, and the results were excellent in point of view of mandibular functions and esthetics.

• The Journal of the Korean dental association
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• v.13 no.3
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• pp.235-238
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• 1975

The authors had treated a patient, 54years korean male, with malignant melanoma, egg sized, in the upper left molar region and hard palate. In the patient, radical operation was made by subtotal maxilectomy and prophylactic neck dissection. We could observe complete healing in the patient with malignant melanoma involving upper left molar region and hard palate.

• Proceedings of the Optical Society of Korea Conference
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• 1989.02a
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• pp.70-72
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• 1989

The laser magnetic resonance (LMR) which makes use of paramagnetic properties of transient species is a powerful technique for the study of molecular radical ions. A liquid nitrogen cooled cw CO laser is developed for the LMR spectrometer in the mid-infrared region of the spectrum. The laser mid-infrared region of the spectrum. The laser system is designed to allow broad-band operation from 5 to 8${\mu}{\textrm}{m}$. The design details will be presented.