• Toxicological Research
• /
• 제28권4호
• /
• pp.241-248
• /
• 2012

Exposure of cells to ultraviolet B (UVB) radiation can induce production of free radicals and reactive oxygen species (ROS), which damage cellular components. In addition, these agents can stimulate the expression of matrix metalloproteinase (MMP) and decrease collagen synthesis in human skin cells. In this study, we examined the anti-photoaging effects of extracts of Tetraselmis suecica (W-TS). W-TS showed the strongest scavenging activity against 2,2-difenyl-1-picrylhydrazyl (DPPH) and peroxyl radicals, followed by superoxide anions from the xanthine/xanthine oxidase system. We observed that the levels of both intracellular ROS and lipid peroxidation significantly increased in UVB-irradiated human skin fibroblast cells. Furthermore, the activities of enzymatic antioxidants (e.g., superoxide dismutase) and the levels of non-enzymatic antioxidants (e.g., glutathione) significantly decreased in cells. However, W-TS pretreatment, at the maximum tested concentration, significantly decreased intracellular ROS and malondialdehyde (MDA) levels, and increased superoxide dismutase and glutathione levels in the cells. At this same concentration, W-TS did not show cytotoxicity. Type 1 procollagen and MMP-1 released were quantified using RT-PCR techniques. The results showed that W-TS protected type 1 procollagen against UVB-induced depletion in fibroblast cells in a dose-dependent manner via inhibition of UVB-induced MMP-1. Taken together, the results of the study suggest that W-TS effectively inhibits UVB-induced photoaging in skin fibroblasts by its strong anti-oxidant ability.

• Nuclear Engineering and Technology
• /
• 제34권1호
• /
• pp.42-59
• /
• 2002

In order to transmute long-lived radioactive nuclides such as transuranics(TRU), Tc-99, and I- l29 in LWR spent fuel, a preliminary conceptual design study has been performed for the accelerator driven subcritical reactor system, called HYPER(Hybrid Power Extraction Reactor) The core has a hybrid neutron energy spectrum: fast and thermal neutrons for the transmutation of TRU and fission products, respectively. TRU is loaded into the HYPER core as a TRU-Zr metal form because a metal type fuel has very good compatibility with the pyre- chemical process which retains the self-protection of transuranics at all times. On the other hand, Tc-99 and I-129 are loaded as pure technetium metal and sodium iodide, respectively. Pb-Bi is chosen as a primary coolant because Pb-Bi can be a good spallation target and produce a very hard neutron energy spectrum. As a result, the HYPER system does not have any independent spallation target system. 9Cr-2WVTa is used as a window material because an advanced ferritic/martensitic steel is known to have a good performance under a highly corrosive and radiation environment. The support ratios of the HYPER system are about 4∼5 for TRU, Tc-99, and I-129. Therefore, a radiologically clean nuclear power, i.e. zero net production of TRU, Tc-99 and I-129 can be achieved by combining 4 ∼5 LWRs with one HYPER system. In addition, the HYPER system, having good proliferation resistance and high nuclear waste transmutation capability, is believed to provide a breakthrough to the spent fuel problems the nuclear industry is faced with.

• Nuclear Engineering and Technology
• /
• 제55권6호
• /
• pp.2315-2324
• /
• 2023

Space nuclear reactors are becoming popular in deep space exploration owing to their advantages of high-power density and stability. Following the fourth-generation nuclear reactor technology, a conceptual design of the dual drum-controlled space molten salt reactor (D²-SMSR) is proposed. The reactor concept uses molten salt as fuel and heat pipes for cooling. A new reactivity control strategy that combines control drums and safety drums was adopted. Critical physical characteristics such as neutron energy spectrum, neutron flux distribution, power distribution and burnup depth were calculated. Flow and heat transfer characteristics such as natural convection, velocity and temperature distribution of the D²-SMSR under low gravity conditions were analyzed. The reactivity control effect of the dual-drums strategy was evaluated. Results showed that the D²-SMSR with a fast spectrum could operate for 10 years at the full power of 40 kWth. The D²-SMSR has a high heat transfer coefficient between molten salt and heat pipe, which means that the core has a good heat-exchange performance. The new reactivity control strategy can achieve shutdown with one safety drum or three control drums, ensuring high-security standards. The present study can provide a theoretical reference for the design of space nuclear reactors.

• 한국전자파학회논문지
• /
• 제29권1호
• /
• pp.36-41
• /
• 2018

본 논문에서는 밀리미터파(W 대역) 다중개구각 혼안테나를 제안하였다. 제안된 안테나는 전계면 및 자계면 빔폭이 동일한 다중모드 이중편파 정사각형 혼으로서 다중모드 생성부, 4개의 정사각형 도파관 여기부, 합패턴 형성을 위한 직교모드 변환기와 전력결합기로 구성된다. 제작이 용이하도록 안테나 구조를 설계하고, 층별 기계가공과 확산접합 기법을 적용하여 ${\pm}0.02mm$ 오차 이내로 제작하였다. 회로망분석기와 원전계 측정시설을 이용하여 제작된 안테나의 입력 반사계수와 방사패턴을 측정하였다. 측정 결과, 제안한 안테나는 중심 주파수를 기준으로 1 GHz 이내에서 17.7~18.3 dBi의 이득, $25.2{\sim}28.5^{\circ}$의 빔폭, 1.02~1.75의 입력 VSWR 특성을 가짐을 확인하였다.

• 한국식생활문화학회지
• /
• 제13권3호
• /
• pp.169-182
• /
• 1998

This study was conducted to investigate the consumers' Dining-out preference and behavior for the chilled meat consumption strategy . A total of 328 persons in Seoul, Kyunggi areas were selected by stratified random sampling method and were responded to this study questionnaire which was composed of six parts with 65 statements about chilled meat consumption. 1. The frequency of Dining-out is characterized that 'once a month' is the highest pattern of consumers(46.3%) : In that cases, the married people showed 'once a month'(52.7%) and 'once biweekly'(23.3%), but the unmarried people showed the more frequent pattern as 'once a week'(27.3%) and 'twice a week'(27.3%). And the frequency of Dining-out in relation with the education level revealed that 'the graduate people' are the highest (37.5%). 2. Generally the first food for the Dining-out is 'Kalbi'(26.2%), and the others were 'pork grilling','chilled meat grilling','fish sasimi','chinese foods','pizza' etc.... But there were some variation in relation with incomes and housing types: For the agriculture/physical labor class, they prefers the 'pork griling'(25.0%), the office work class prefers the 'Kalbi' For the house-owner group, they prefers the 'Kalbi', but the house-renting/lodging group, they prefer the 'chinese food' or 'pork grilling' etc.... 3. In choosing the Dining-out place,'quality of food'(54.3%) and 'hygiene'(21.0%) were rated as the first important factor. 4.'Soups', 'Noodles' and 'Cooked rice in casserole' were chosen as good lunch menu : for male, they prefer the 'Soups', but females prefer 'Cooked rice in casserole'. 5. People with commercials/services(44.7%) and agriculture/physical labor(50.0%) ate their lunch in private restaurant, but peoples in the office work(57.0%)/public service personnel(70.4%) and industry use refectory; and it showed significant difference. 6. Consumers prefer the chilled meat as a Dining-out menu, but they didn't recognize the difference between chilled meat and frozen meat 7. For Dining-out menu, many people proper the beef, but the price of beef was so high than pork, agriculture/physical labor class choose the pork grilling instead of beef : commercials/services/office worker prefer the beef chilled meat . 8. The first admirable cooking method for chilled meat is direct radiation grilling with charcoal and many of consumers prefer tender, marbling, some chewy and juicy, flavor, soft as a quality of meat but physical labor class prefer the some tough and chewy texture.

• 한국식품영양과학회지
• /
• 제40권11호
• /
• pp.1604-1611
• /
• 2011

미역귀를 이용한 가공식품개발을 위해 비조사구와 감마선 조사구의 미역귀 열수추출 분말을 첨가(1, 3, 5, 7%)한 쿠키를 제조하여 품질 특성을 알아보았다. 쿠키 반죽의 pH는 미역귀 열수추출 분말 첨가에 의해 감소하였으나, 밀도에는 영향이 없는 것으로 나타났다. 쿠키의 퍼짐성은 분말 첨가량의 증가에 따라 점차 증가하였으며 같은 첨가량에서 비조사구에 비해 조사구의 퍼짐성이 높음이 나타났다. 손실률은 대조구 및 실험구 사이에 유의성이 없었으며, 팽창률은 첨가량이 높을수록 증가함을 보였고 비조사구와 조사구를 비교하였을 때는 조사구의 팽창률이 더 높음을 보였다. 쿠키의 색도 측정 결과 중 L값(lightness)은 첨가량이 증가할수록 감소하였으며, b값(yellowness)은 비조사구에서는 첨가구간 유의차를 나타내지 않았으나 조사구에서는 첨가량이 증가할수록 낮아지는 경향을 보였다. a값(redness)은 비조사구에서 첨가구간의 유의차를 보이지 않은 반면, 조사구에서는 첨가량이 증가할수록 증가함을 보였다. 쿠키의 경도는 미역귀 열수추출 분말 첨가량이 증가할수록 증가하였으며, 항산화 활성 또한 7% 첨가구에서 가장 높은 값을 보였으며, 같은 첨가량에서 비조사구에 비해 감마선 조사한 첨가구에서 높은 항산화 활성을 보였다. 쿠키의 관능검사 결과 미역귀 열수추출 분말 첨가는 색, 냄새, 맛, 질감 및 전체적인 기호도를 향상시키는 긍정적인 영향을 미치나 너무 많은 미역귀 열수추출 분말 첨가는 관능적인 기호도를 오히려 떨어 뜨리는 것으로 나타남에 따라 선호도 결과 비조사 3% 첨가구와 조사 1% 첨가구의 선호도가 가장 좋게 나타났다. 이에 미역귀의 항산화 활성은 첨가량의 증가에 따라 증가하는 경향을 나타내었으나 항산화 활성의 유의적인 증가 지점에서 쿠키의 관능 선호도가 감소되므로, 적은 첨가량으로 쿠키의 품질 및 관능 특성, 기능성에서 우수하며 산업적으로도 활용 가능한 조사 1% 첨가구가 최적 조건일 것으로 판단되었다.

• 방사선산업학회지
• /
• 제9권2호
• /
• pp.85-90
• /
• 2015

Purpose: Time of operation has been reduced and accuracy of operation has been improved since C-arm, which offer real-time image of patient, was introduced in operation room. However, because of the contamination of patient, C-arm could not be used more appropriately. Therefore, this study is to know factors of controlling exposure dose, image quality and the exposed dose of health professional in operation room. Materials and methods: Height of Wilson frame (bed for operation) was fixed at 130 cm. Then, Model 76-2 Phantom, which was set by assembling manual of Fluke Company, was set on the bed. Head/Spine Fluoroscopy AEC mode was set for exposure condition. According to detector size of C-arm, the absorbed dose per min was measured in the 7 steps OFD (cm) from 10 cm to 40 cm (10, 15, 20, 25, 30, 35, 40 cm). In each step of OFD, the absorbed dose per min of same diameter of collimation was measured. Moreover, using Nero MAX Model 8000, exposure dose per min was measured according to 3 step of distance from detector (20 cm, 60 cm, 100 cm). Finally, resolution was measured by CDRH Disc Phantom and magnification of each OFD was measured by aluminum stick bar. Result: According to detector size of C-arm, difference of absorbed dose shows that the dose of 20 cm OFD is 1.750 times higher than the dose of 40 cm OFD. It means that the C-arm, which has smaller size of detector, shows the bigger difference of absorbed dose per min (p<0.05). In the difference of absorbed dose in the same step of OFD (from 20 cm to 40 cm), the absorbed dose of 9 inch detect or C-arm was 1.370 times higher than 12 inch' s (p<0.05). When OFD was set to 20 cm OFD, the absorbed dose of non-collimation case was approximately 0.816 times lower than the absorbed dose of collimation cases (p<0.05). When the distance was 20 cm from detector, exposed does includes first-ray and scatter-ray. When the distance was 60 cm and 100 cm from detector, exposed does includes just scatter-ray. So, there was the 2.200 times difference of absorbed does. Finally, when OFD was increased, spatial resolution was 4 to 5 step was increased. However, low contrast resolution was not relative. Moreover, there was 1.363 times difference of magnification (p<0.05). Conclusion: When C-Arm is used, avoiding contamination of patient is more important factor than reducing exposed dose of health professional in operation room. Just controlling exposure time is just way to reduce the exposed does of workers. However, in the case, non-probability influence could be occurred. Therefore, this study proved that the exposed dose will be reduced if the factors such as using small detector size of C-arm, setting OFD from 20 cm to 25 cm and non-collimating. Moreover, dose management of C-arm in the non-interesting area will be considered additionally.

• 방사선산업학회지
• /
• 제7권1호
• /
• pp.7-14
• /
• 2013

In this study, we investigated the applicability of the photostimulated luminescence (PSL), thermoluminescence (TL) and electron spin resonance (ESR) methods for various foods. The analysed samples consist of 11 items including dried fruits (6 items) and mushrooms (5 items). To compare between non-irradiated and irradiated food, all samples were irradiated with $^{60}Co$ gamma-ray source. In PSL study, the photon counts of all the unirradiated sample were identified negative (lower than 700). The photon counts irradiated (1, 5, 10 kGy) dried date-palm, dried jujube and mushrooms (Auricularia auricula, Phellinus linteus and Sarcodon aspratus) showed positive (higher than 5,000) and the results for the other samples were negative or intermediate (>700 and >5,000). In TL analysis most of items can be applicable to detect irradiated foods because of showing TL ratio above 0.1. The glow curves by TL method were estimated in the range of $150{\sim}250^{\circ}C$ in irradiated samples. In ESR measurements, the intensity of ESR signal (single-line) increased as the dose of irradiation increased. In particular, the specific ESR signals of irradiation-induced radical were detected in dried papaya, dried date-palm, dried banana, dried pineapple and S. aspratus. According to the results, PSL, TL and ESR methods were successfully applied to detect the irradiated foods. It is concluded that PSL, TL and ESR methods are suitable for detection of irradiated samples and a combined method is recommendable for enhancing the reliability of detection results.

• 한국방사선학회논문지
• /
• 제15권1호
• /
• pp.45-54
• /
• 2021

본 연구는 혼합현실을 기반으로 하는 비파괴 분야의 교육용콘텐츠를 만들기 위해 시행되었다. 현재 방사선 분야에는 교육용 혼합현실 기반 교육용 콘텐츠는 거의 없는 실정이다. 그리고 비파괴검사분야는 작업 환경이 열악하고, 종사자 수도 한 업체당 직원 수가 10인 이하인 곳이 많고, 교육적 인프라도 잘 구축되어 있지 않다. 강의식으로 전달만 하는 실습교육과 안전교육이 시행되고 있다. 이를 해결하기 위해 혼합현실을 기반으로 한 비파괴 종사자 교육용 콘텐츠를 개발하게 되었다. 이 콘텐츠는 Microsoft사의 HoloLens 2 HMD 디바이스를 기반으로 개발되었고, 1280⁎720의 해상도를 기준으로 제작되었고, 디바이스마다 해상도가 달라 Anchor의 Left, Right, Bottom, TOP위치를 맞추어 Side를 제작하였고, 이미지가 큰 것은 Atlas의 크기에 영향을 미치기 때문에 배경화면이나 상단 바와 같이 부피가 큰 것은 UITexture로 대체하여 제작되었다. UI Widget Wizard에서는 Label, Buttom, ScrollView, Sprite를 제작하였다. 본 연구는 종사자에게 현장감 있는 교육내용을 제공하고, 자기 주도적인 교육을 가능하게 하고, 현실을 바탕으로 한 3D 입체영상으로 교육할 수 있어 흥미와 몰입도 있는 교육을 시행할 수 있다. 혼합현실에서 제공되는 영상을 통해 현실세계와 가상현실 간에 상호작용을 통해 학습자가 직접 사물을 조작할 수 있어 학습자의 학습 능률을 높일 수 있다. 또한 혼합현실 교육을 시행하면 시간과 장소에 구해를 받지 않아 코로나 시대에 비대면 학습 콘텐츠로 큰 역할을 할 수 있을 것으로 사료된다.

• 공업화학
• /
• 제29권1호
• /
• pp.81-96
• /
• 2018

본 연구에서는 천연 소재인 경옥가루의 물리화학적 특성을 조사하고 이를 함유한 워시오프 팩과 리퀴드 파운데이션을 제조하였다. 또한 이들 제형을 대상으로 각 제형이 주는 효과와 사용자 관능 평가, 제형 안정성 및 피부 안전성 평가를 수행하였다. 워시오프 팩 중의 경옥가루의 함량이 증가할수록 원적외선 방사율과 방사에너지 값이 증가하였고, 경옥가루를 3% 함유한 제품에서는 피부 적용 시 피부 온도가 약 $0.5^{\circ}C$ 상승하였다. 경옥가루를 첨가한 리퀴드 파운데이션은 피부 본래의 색을 더욱 선명하게 표현할 수 있는 채도를 나타냈다. 경옥가루를 첨가한 워시오프 팩과 리퀴드 파운데이션은 각각의 수분 보유량이 최대 5.0% 및 63.0%로 나타났다. 사용자 관능 평가에서 경옥가루를 함유한 워시오프 팩 제형은 피부친화력, 밀착력, 가려움 및 촉촉함을 개선시켰다. 경옥가루를 함유한 리퀴드 파운데이션도 대조군 제형과 비교했을 때 커버력을 제외한 모든 항목에서 개선이 이루어졌다. 경옥가루 함유 제형에 대해 8주간 안정성 평가를 한 결과 육안상으로 변색이나 분리현상은 관찰되지 않았으며 pH는 8주까지, 점도는 4주까지 안정함을 확인하였다. 또한, 피부 안전성 평가에서 경옥가루 함유 제형은 모두 자극이 없는 것으로 나타났다. 결론적으로, 경옥가루는 무기안료로써 안정성과 안전성이 확보된 새로운 다기능 소재로써 화장품에 응용 가능성이 있음을 시사하였다.